Clinical Research Manager Jobs in USA with Visa Sponsorship
Clinical Research Managers oversee trial operations, regulatory submissions, and site coordination, roles that consistently qualify as specialty occupations under H-1B visa and E-3 visas. Most employers in this field sponsor because qualified candidates are scarce and degree requirements are clearly defined. For detailed occupation requirements, see the O*NET profile.
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Get Access To All JobsJob Ref:
JR-8588
Location:
10 Brookline Place, BROOKLINE, MA 02445
Category:
Clinical Research
Employment Type:
Full time
Work Location:
Hybrid: 2-3 days onsite/week
Salary/Pay Rate:
$77,400.00 - $102,800.00 per year
Overview
The Clinical Research Manager (CRM) will work within the Gynecologic Oncology Translational/Biobanking research program & manage the research team in the overall conduct of clinical trials using Good Clinical Practice under the auspices of the Principal Investigator and the Clinical Trials Office. The Clinical Research Manager, in collaboration with the program’s physicians and research nursing staff, are responsible for the design, implementation and evaluation of their program’s clinical research activities (therapeutic and non-therapeutic), all related regulatory and compliance oversight, and direct supervision of their program’s clinical research staff. The Clinical Research Manager is responsible for tracking and complying with clinical trial performance benchmarks; e.g. protocol and regulatory compliance, patient safety, staff development & training and financial goals, as defined by Senior Research Leadership and the DFCI Clinical Trials Office.
This position’s work location is hybrid with 2-3 days onsite in Boston, MA per week. The selected candidate may only work remote days from a New England state (ME, VT, NH, MA, CT, RI). Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
PRIMARY DUTIES AND RESPONSIBILITIES:
- Clinical Research Managers (CRM) are responsible for the oversight of their disease group’s clinical trial portfolio and all related regulatory, compliance and performance metrics requirements.
- Oversee the processing of protocols through DFCI Institutional Review Board (and other institutions’ IRBs) when appropriate. The CRM will collaborate with the DFCI Clinical Trials Office (CTO), the Office for Human Research Studies (OHRS), and the Office of Data Quality (ODQ) to fulfill local and federal requirements governing human clinical trials.
- Identify and manage operational, logistical, and regulatory challenges related to the conduct of clinical trials and acts as a leader in overseeing their resolution.
- Oversees and coordinates the purchase, receipt, inventory and distribution of equipment utilized in the conduct of clinical trials.
- In collaboration with clinical research administration and grant managers, may maintain, monitor and reconcile all study and related grant finances. These may include budget development, expenditure tracking, procurement, salary offset worksheets and staffing.
- Assists the principal investigator in preparing manuscripts for publication.
- Collaborate with the DFCI CTO, and DF/HCC ODQ to develop study forms, database information, and to establish guidelines for monitoring data quality control for PI Initiated studies / Multi-Center Trials.
- Oversee the subject enrollment, protocol treatment and follow-up care processes for protocol patients.
- Oversees registration of protocol patients with ODQ or OnCore policies and pharmaceutical company as outlined in protocol.
- If applicable for coverage or trial assignments, responsible for data entry of study-specific activity, including but not limited to subject visit tracking, monitor visits, external site enrollment, amendments, receipt of Safety Reports, etc. into Clinical Trial Management System contemporaneously with activity completed.
- Responsible for reviewing, approving, and reporting on data entry completed by supervised research staff in Clinical Trial Management System. The data entry oversight may include, but is not limited to, Subject Visit Tracking for subject-specific visits, time and effort spent on study-specific activities and other administrative tasks, etc.
Regulatory & Compliance
- Assumes responsibility for essential document compliance for entire portfolio. Implements systems to monitor and ensure regulatory document collection and maintenance compliance.
- Assumes responsibilities for all clinical trial reporting requirements; safety event, annual approval, deviations etc. Implements systems to monitor portfolio compliance.
- Responsible for the disease group’s transition from paper to electronic regulatory binders. Will maintain per DFCI CTO standards.
Data Management & Clinical Trial Monitoring
- Assumes responsibilities for data management and compliance for entire portfolio. Maintains schedules and procedures necessary for timely and complete data collection.
- Regularly reports data compliance status to key stakeholders; i.e. DFCI PI, study Sponsor, DFCI CTO. Implements corrective action to maintain data compliance when necessary.
- Submits required “progress / tracking” reports to key stakeholders, when applicable.
Staff Hiring, Supervision, Training & Development
- Responsible for the recruitment and oversight of all of the research staff. Ensure that all staff complete required mandatory and ongoing training in a timely manner. Develops and oversees a program specific onboarding and orientation process and conducts annual performance evaluations and competency assessments of research staff.
- Develops a standard supervision schedule with research staff including periodic individual and group supervision meeting. Will develop an agenda, take attendance and document all applicable meetings.
- Will communicate all personnel concerns to their immediate supervisor and to DFCI HR partner for the appropriate response and follow up.
SUPERVISORY RESPONSIBILITIES:
Supervises study management staff, including clinical research coordinators, students, volunteers, and other research assistants. Number of direct reports 1-5.
COMPETENCIES:
- Must be able to perform day to day responsibilities independently with minimal supervision from manager.
- Must be somewhat proficient in the following; identifying complex regulatory scenarios that require consultation, clinical trials start-up, active and close out phases, clinical research local policy and federal regulation.
- Must have some proficiency to manage personnel issues and to provide critical feedback to supervisees, when applicable.
MINIMUM QUALIFICATIONS:
Bachelor’s Degree required, with a minimum of 5 years of related experience preferred. Must be able to function independently and must have previous supervisory experience.
KNOWLEDGE, TECHNICAL SKILLS, AND ABILITIES REQUIRED:
- Knowledge of cancer as a disease process, cancer treatment modalities, and the clinical trial process.
- Experience in protocol development, data compilation and analysis.
- Skilled at developing tracking systems to ensure timely data management by the clinical research staff.
- Expert knowledge of Federal and State regulations as they relate to research. Strong interpersonal, organizational and communication skills are required.
- Must have computer skills including the use of Microsoft Office and working knowledge of Livelink; EPIC and OnCore applications.
PATIENT CONTACT:
May have contact with patients of all ages and populations.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEO Poster
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$77,400.00 - $102,800.00
Job Ref:
JR-8588
Location:
10 Brookline Place, BROOKLINE, MA 02445
Category:
Clinical Research
Employment Type:
Full time
Work Location:
Hybrid: 2-3 days onsite/week
Salary/Pay Rate:
$77,400.00 - $102,800.00 per year
Overview
The Clinical Research Manager (CRM) will work within the Gynecologic Oncology Translational/Biobanking research program & manage the research team in the overall conduct of clinical trials using Good Clinical Practice under the auspices of the Principal Investigator and the Clinical Trials Office. The Clinical Research Manager, in collaboration with the program’s physicians and research nursing staff, are responsible for the design, implementation and evaluation of their program’s clinical research activities (therapeutic and non-therapeutic), all related regulatory and compliance oversight, and direct supervision of their program’s clinical research staff. The Clinical Research Manager is responsible for tracking and complying with clinical trial performance benchmarks; e.g. protocol and regulatory compliance, patient safety, staff development & training and financial goals, as defined by Senior Research Leadership and the DFCI Clinical Trials Office.
This position’s work location is hybrid with 2-3 days onsite in Boston, MA per week. The selected candidate may only work remote days from a New England state (ME, VT, NH, MA, CT, RI). Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
PRIMARY DUTIES AND RESPONSIBILITIES:
- Clinical Research Managers (CRM) are responsible for the oversight of their disease group’s clinical trial portfolio and all related regulatory, compliance and performance metrics requirements.
- Oversee the processing of protocols through DFCI Institutional Review Board (and other institutions’ IRBs) when appropriate. The CRM will collaborate with the DFCI Clinical Trials Office (CTO), the Office for Human Research Studies (OHRS), and the Office of Data Quality (ODQ) to fulfill local and federal requirements governing human clinical trials.
- Identify and manage operational, logistical, and regulatory challenges related to the conduct of clinical trials and acts as a leader in overseeing their resolution.
- Oversees and coordinates the purchase, receipt, inventory and distribution of equipment utilized in the conduct of clinical trials.
- In collaboration with clinical research administration and grant managers, may maintain, monitor and reconcile all study and related grant finances. These may include budget development, expenditure tracking, procurement, salary offset worksheets and staffing.
- Assists the principal investigator in preparing manuscripts for publication.
- Collaborate with the DFCI CTO, and DF/HCC ODQ to develop study forms, database information, and to establish guidelines for monitoring data quality control for PI Initiated studies / Multi-Center Trials.
- Oversee the subject enrollment, protocol treatment and follow-up care processes for protocol patients.
- Oversees registration of protocol patients with ODQ or OnCore policies and pharmaceutical company as outlined in protocol.
- If applicable for coverage or trial assignments, responsible for data entry of study-specific activity, including but not limited to subject visit tracking, monitor visits, external site enrollment, amendments, receipt of Safety Reports, etc. into Clinical Trial Management System contemporaneously with activity completed.
- Responsible for reviewing, approving, and reporting on data entry completed by supervised research staff in Clinical Trial Management System. The data entry oversight may include, but is not limited to, Subject Visit Tracking for subject-specific visits, time and effort spent on study-specific activities and other administrative tasks, etc.
Regulatory & Compliance
- Assumes responsibility for essential document compliance for entire portfolio. Implements systems to monitor and ensure regulatory document collection and maintenance compliance.
- Assumes responsibilities for all clinical trial reporting requirements; safety event, annual approval, deviations etc. Implements systems to monitor portfolio compliance.
- Responsible for the disease group’s transition from paper to electronic regulatory binders. Will maintain per DFCI CTO standards.
Data Management & Clinical Trial Monitoring
- Assumes responsibilities for data management and compliance for entire portfolio. Maintains schedules and procedures necessary for timely and complete data collection.
- Regularly reports data compliance status to key stakeholders; i.e. DFCI PI, study Sponsor, DFCI CTO. Implements corrective action to maintain data compliance when necessary.
- Submits required “progress / tracking” reports to key stakeholders, when applicable.
Staff Hiring, Supervision, Training & Development
- Responsible for the recruitment and oversight of all of the research staff. Ensure that all staff complete required mandatory and ongoing training in a timely manner. Develops and oversees a program specific onboarding and orientation process and conducts annual performance evaluations and competency assessments of research staff.
- Develops a standard supervision schedule with research staff including periodic individual and group supervision meeting. Will develop an agenda, take attendance and document all applicable meetings.
- Will communicate all personnel concerns to their immediate supervisor and to DFCI HR partner for the appropriate response and follow up.
SUPERVISORY RESPONSIBILITIES:
Supervises study management staff, including clinical research coordinators, students, volunteers, and other research assistants. Number of direct reports 1-5.
COMPETENCIES:
- Must be able to perform day to day responsibilities independently with minimal supervision from manager.
- Must be somewhat proficient in the following; identifying complex regulatory scenarios that require consultation, clinical trials start-up, active and close out phases, clinical research local policy and federal regulation.
- Must have some proficiency to manage personnel issues and to provide critical feedback to supervisees, when applicable.
MINIMUM QUALIFICATIONS:
Bachelor’s Degree required, with a minimum of 5 years of related experience preferred. Must be able to function independently and must have previous supervisory experience.
KNOWLEDGE, TECHNICAL SKILLS, AND ABILITIES REQUIRED:
- Knowledge of cancer as a disease process, cancer treatment modalities, and the clinical trial process.
- Experience in protocol development, data compilation and analysis.
- Skilled at developing tracking systems to ensure timely data management by the clinical research staff.
- Expert knowledge of Federal and State regulations as they relate to research. Strong interpersonal, organizational and communication skills are required.
- Must have computer skills including the use of Microsoft Office and working knowledge of Livelink; EPIC and OnCore applications.
PATIENT CONTACT:
May have contact with patients of all ages and populations.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEO Poster
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$77,400.00 - $102,800.00
See all 8,133+ Clinical Research Manager Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Clinical Research Manager roles.
Get Access To All JobsTips for Finding Visa Sponsorship as a Clinical Research Manager
Target employers with existing IND or NDA filings
Pharmaceutical companies and CROs actively running clinical trials are far more likely to sponsor. They have established immigration infrastructure and ongoing hiring needs that make the sponsorship process routine rather than a one-off exception.
Emphasize your regulatory and protocol experience
Employers sponsoring Clinical Research Managers want evidence you can manage FDA-regulated trials independently. GCP certification, experience with IRB submissions, and protocol deviation management all strengthen the case for your visa petition significantly.
Clarify your degree field upfront in applications
H-1B specialty occupation requires a directly related degree. Life sciences, nursing, public health, or clinical research degrees are strong fits. Unrelated degrees can complicate petitions, so address the connection to your role explicitly in your cover letter.
Ask about cap-exempt employers during your search
Research hospitals affiliated with universities and nonprofit research institutions are often cap-exempt H-1B employers. That means no lottery and faster hiring timelines, a major advantage if you missed the H-1B registration window this cycle.
Understand the LCA's prevailing wage requirement
Your employer must certify they'll pay at least the prevailing wage for Clinical Research Managers in your work location. This is filed before your visa petition and protects both you and the employer from compliance issues down the line.
Use Migrate Mate to filter for verified sponsor-ready roles
Not every Clinical Research Manager listing comes from an employer willing to sponsor. Migrate Mate surfaces jobs from companies with documented sponsorship history, so you spend less time on applications that lead nowhere.
Frequently Asked Questions
Does a Clinical Research Manager role qualify as an H-1B specialty occupation?
Yes, consistently. USCIS treats Clinical Research Manager positions as specialty occupations because the role typically requires at minimum a bachelor's degree in a specific field, life sciences, nursing, pharmacy, or public health being the most common. The key is that your employer's job description must reflect these degree requirements explicitly, not just list them as preferred.
Which visa types do Clinical Research Managers most commonly use to work in the U.S.?
H-1B visa is the most common path for non-Australian nationals. Australians can use the E-3 visa, which has no lottery and shorter processing times. Canadian and Mexican nationals may qualify under the TN visa if the role maps to an eligible TN category, though this requires careful review. O-1A is an option for senior researchers with demonstrated national or international recognition.
How often do employers actually sponsor Clinical Research Managers?
Sponsorship is relatively common in this field compared to many others. Large pharmaceutical companies, contract research organizations like ICON and Labcorp Drug Development, and academic medical centers regularly sponsor because the talent pool is specialized. Employers with ongoing trial portfolios treat sponsorship as a standard hiring cost rather than an exception.
Does my degree field matter for a Clinical Research Manager H-1B petition?
It matters significantly. USCIS looks for a direct connection between your degree and the role. Degrees in biology, clinical science, nursing, pharmacy, or public health are strong. A degree in an unrelated field, such as business or engineering, can trigger an RFE. In those cases, your attorney may need to document how the degree nonetheless supports the specific duties of the position.
Where can I find Clinical Research Manager jobs from employers willing to sponsor?
Migrate Mate is built specifically for this, it aggregates roles from employers with verified sponsorship history, so you're not guessing which companies will actually support a visa petition. Filtering by visa type lets you focus on H-1B, E-3, or TN visa-eligible roles without wading through listings from employers who won't sponsor.
What is the prevailing wage requirement for sponsored Clinical Research Manager jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.