Clinical Lead Jobs in New York
Clinical Lead jobs in New York are in strong demand, with the market concentrated in healthcare systems, behavioral health networks, and research-driven academic medical centers serving candidates from senior clinician through department director level. The heaviest hiring is in New York City, Buffalo, and Albany, where institutions such as NewYork-Presbyterian, Northwell Health, and NYC Health and Hospitals consistently fill clinical lead openings. The most in-demand specialties include behavioral health program leadership, oncology care coordination, and quality improvement. Find a role that fits below and apply directly.
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Syndax Pharmaceuticals is looking for an Executive Director, Asset Strategy Lead and Clinical Lead, Early Development
At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. Syndax Pharmaceuticals is a commercial stage biopharmaceutical company developing an innovative pipeline of cancer therapies.
The Role:
The Asset Strategy Lead (ASL), Early Development provides leadership to a cross-functional strategic asset team and leads the development and execution of the asset strategy. Further, the ASL champions the product/brand at all levels of Syndax and is responsible for managing the alignment on communication on all Asset Strategy Team (AST) matters, as appropriate.
We are seeking an Executive Director, Asset Strategy Lead for our recently announced Next Generation Menin Program. During the early stages of development, the role will also assume the responsibility of clinical lead for the program. The ideal candidate will bring a demonstrated record of strategic leadership and operational excellence in global oncology product development, with experience leading early-stage programs through pre-IND activities through pivotal studies, and potentially regulatory approval and commercialization.
This role will be a key member of the Syndax senior leadership team, influencing portfolio strategy and execution. The ideal candidate will lead the asset with a long-term enterprise view, integrating scientific, clinical, regulatory, commercial, and financial perspectives to optimize asset value.
Key Responsibilities:
- Own end-to-end leadership of the asset strategy, from early development through regulatory filings, approval, launch, and lifecycle management.
- Drive the strategic direction of the program in alignment with corporate objectives, balancing scientific innovation, clinical value, and commercial opportunity.
- Identifies potential issues and leads contingency planning; leads AST problem solving and applies decision-making tools and techniques. Drives AST to make effective and efficient decisions.
- Serve as a key liaison to the Executive Leadership Team, providing updates, insights, and recommendations that inform enterprise decisions.
- Lead long-range planning, including scenario planning, investment strategy, and external innovation assessments related to the asset.
- Partner with Commercial, Medical Affairs, Regulatory, and Development to shape Target Product Profile (TPP) and ensure robust lifecycle and global expansion planning.
- Leads resolution of conflict at the AST and oversees governance engagement, ensuring timely and transparent communication on key decisions, risks, budgets, and timelines.
- Foster a culture of accountability, innovation, and excellence, modeling strong leadership and collaborative behaviors.
- Represent Syndax in strategic partnerships, collaborations, and scientific/medical forums as appropriate.
Desired Experience/Education and Personal Attributes:
- Educational Requirements: Advanced degree in life sciences, medicine, or business (e.g., PhD, MD, MBA) highly preferred.
- A minimum of 10 or more years of experience in leading clinical development programs in oncology is required.
- Equivalent experience in a leadership role as a part of a research-driven pharmaceutical company is required.
- Proven track record of successfully leading global cross-functional teams through IND, early development and pivotal studies; experience with BLA/NDA and launch phases is a plus.
- Deep knowledge of oncology product development, regulatory environments, and commercialization strategies.
- Strong strategic acumen with the ability to anticipate market dynamics and influence enterprise-level decisions.
- Prior experience interacting with C-suite executives, external partners, and regulators.
- Highly collaborative, with strong influencing skills and ability to work across multiple levels and functions.
- Executive presence and outstanding communication skills, including comfort presenting to senior and external audiences.
- Experience with portfolio management, financial modeling, and program valuation is highly desirable.
Location: Syndax's corporate office is in New York, NY.
Syndax offers a total compensation and rewards package that is among the most competitive in the industry. Base pay is just one element of our package and is determined within a range based on several factors including market data, experience, qualifications, demonstrated skills, relevant education or training, travel requirements and internal equity. Our overall package also includes an equity offering, annual target bonuses, and an outstanding benefits program. The anticipated annualized salary range for this role is $370,000 - $400,000.
About Syndax:
Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company advancing innovative cancer therapies. Highlights of the Company's pipeline include a menin inhibitor for R/R acute leukemia and a monoclonal antibody that blocks the CSF-1 receptor for chronic graft-versus-host disease. Fueled by our commitment to reimagining cancer care, Syndax is working to unlock the full potential of its pipeline and is conducting several clinical trials across the continuum of treatment. For more information, please visit www.syndax.com/ or follow the Company on X and LinkedIn.
Syndax Pharmaceuticals is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
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Syndax Pharmaceuticals is looking for an Executive Director, Asset Strategy Lead and Clinical Lead, Early Development
At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. Syndax Pharmaceuticals is a commercial stage biopharmaceutical company developing an innovative pipeline of cancer therapies.
The Role:
The Asset Strategy Lead (ASL), Early Development provides leadership to a cross-functional strategic asset team and leads the development and execution of the asset strategy. Further, the ASL champions the product/brand at all levels of Syndax and is responsible for managing the alignment on communication on all Asset Strategy Team (AST) matters, as appropriate.
We are seeking an Executive Director, Asset Strategy Lead for our recently announced Next Generation Menin Program. During the early stages of development, the role will also assume the responsibility of clinical lead for the program. The ideal candidate will bring a demonstrated record of strategic leadership and operational excellence in global oncology product development, with experience leading early-stage programs through pre-IND activities through pivotal studies, and potentially regulatory approval and commercialization.
This role will be a key member of the Syndax senior leadership team, influencing portfolio strategy and execution. The ideal candidate will lead the asset with a long-term enterprise view, integrating scientific, clinical, regulatory, commercial, and financial perspectives to optimize asset value.
Key Responsibilities:
- Own end-to-end leadership of the asset strategy, from early development through regulatory filings, approval, launch, and lifecycle management.
- Drive the strategic direction of the program in alignment with corporate objectives, balancing scientific innovation, clinical value, and commercial opportunity.
- Identifies potential issues and leads contingency planning; leads AST problem solving and applies decision-making tools and techniques. Drives AST to make effective and efficient decisions.
- Serve as a key liaison to the Executive Leadership Team, providing updates, insights, and recommendations that inform enterprise decisions.
- Lead long-range planning, including scenario planning, investment strategy, and external innovation assessments related to the asset.
- Partner with Commercial, Medical Affairs, Regulatory, and Development to shape Target Product Profile (TPP) and ensure robust lifecycle and global expansion planning.
- Leads resolution of conflict at the AST and oversees governance engagement, ensuring timely and transparent communication on key decisions, risks, budgets, and timelines.
- Foster a culture of accountability, innovation, and excellence, modeling strong leadership and collaborative behaviors.
- Represent Syndax in strategic partnerships, collaborations, and scientific/medical forums as appropriate.
Desired Experience/Education and Personal Attributes:
- Educational Requirements: Advanced degree in life sciences, medicine, or business (e.g., PhD, MD, MBA) highly preferred.
- A minimum of 10 or more years of experience in leading clinical development programs in oncology is required.
- Equivalent experience in a leadership role as a part of a research-driven pharmaceutical company is required.
- Proven track record of successfully leading global cross-functional teams through IND, early development and pivotal studies; experience with BLA/NDA and launch phases is a plus.
- Deep knowledge of oncology product development, regulatory environments, and commercialization strategies.
- Strong strategic acumen with the ability to anticipate market dynamics and influence enterprise-level decisions.
- Prior experience interacting with C-suite executives, external partners, and regulators.
- Highly collaborative, with strong influencing skills and ability to work across multiple levels and functions.
- Executive presence and outstanding communication skills, including comfort presenting to senior and external audiences.
- Experience with portfolio management, financial modeling, and program valuation is highly desirable.
Location: Syndax's corporate office is in New York, NY.
Syndax offers a total compensation and rewards package that is among the most competitive in the industry. Base pay is just one element of our package and is determined within a range based on several factors including market data, experience, qualifications, demonstrated skills, relevant education or training, travel requirements and internal equity. Our overall package also includes an equity offering, annual target bonuses, and an outstanding benefits program. The anticipated annualized salary range for this role is $370,000 - $400,000.
About Syndax:
Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company advancing innovative cancer therapies. Highlights of the Company's pipeline include a menin inhibitor for R/R acute leukemia and a monoclonal antibody that blocks the CSF-1 receptor for chronic graft-versus-host disease. Fueled by our commitment to reimagining cancer care, Syndax is working to unlock the full potential of its pipeline and is conducting several clinical trials across the continuum of treatment. For more information, please visit www.syndax.com/ or follow the Company on X and LinkedIn.
Syndax Pharmaceuticals is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
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See All 30 Clinical Lead Jobs in New York
Find roles in New York that match your experience and apply in just a few clicks.
Find Clinical Lead JobsClinical Lead Jobs by City in New York
Where New York roles are concentrated, by current openings.
Clinical Lead Job Market in New York
A snapshot from current New York openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
- Education
- Science & Research
- Non-Profit & Social Services
What New York Employers Look For
The qualifications that appear most often in clinical lead jobs across New York.
- Active New York State clinical license relevant to the care setting and specialty
- Bachelor's degree in nursing, social work, or a related clinical field required
- Minimum three years of direct clinical practice in a relevant care setting
- Demonstrated experience supervising or mentoring clinical staff or care teams
- Proficiency with electronic health record systems such as Epic or Cerner
- Strong knowledge of Joint Commission standards and New York State DOH regulations
Clinical Lead Jobs in New York: Frequently Asked Questions
How do you become a clinical lead in New York?
The path to a clinical lead role in New York starts with an active New York State license in your clinical discipline, issued through the New York State Education Department Office of the Professions. For nurses, that means passing NCLEX and holding a current RN license. Employers typically also expect a bachelor's degree and several years of hands-on clinical practice before moving into a lead role. Pursuing a specialty certification recognized by your field strengthens your candidacy considerably.
Which companies hire clinical leads in New York?
Employers hiring clinical leads in New York right now include St. Peter's Health Partners, American Heart Association, and MetroPlusHealth, based on current listings on Migrate Mate as of August 2026. New York's large integrated health systems and public hospital networks make it one of the most active states for this role, with consistent openings across inpatient, outpatient, and community health settings.
Which New York cities have the most clinical lead jobs?
The cities with the most clinical lead openings in New York are New York, Albany, and Syracuse. New York City dominates the distribution because it anchors the state's largest academic medical centers and public hospital systems, while Buffalo and Albany generate steady demand through regional health networks and state government-affiliated health programs serving their surrounding communities.
Are there remote clinical lead jobs in New York?
Yes, but they're rare. Clinical lead roles are largely hands-on positions requiring direct oversight of care teams and in-person patient environment accountability, so remote work is the exception rather than the norm. About 67% of clinical lead openings tied to New York are remote or hybrid as of August 2026, and those positions tend to sit in utilization review, care management, or telehealth program leadership rather than bedside or unit-based lead roles.
How can I get hired as a clinical lead in New York with little or no experience?
The most realistic entry path is moving from a staff clinician role into a charge nurse, senior care coordinator, or team lead position first. Large New York employers such as Northwell Health and NYC Health and Hospitals run new-graduate residency and clinical development programs that build the supervisory skills needed for a lead title. Earning a specialty certification through a recognized nursing or clinical body and volunteering for quality improvement or preceptor duties signals leadership readiness to New York hiring managers before you carry an official lead title.
Where can I find and apply to clinical lead jobs in New York?
You can find and apply to clinical lead jobs in New York on Migrate Mate, which lists current New York openings from employers actively hiring. Search the listings, find roles that match your credentials and preferred setting, and apply directly to the ones that fit.
See All 30 Clinical Lead Jobs in New York
Find roles in New York that match your experience and apply in just a few clicks.
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