Clinical Nurse Jobs in Iowa

Clinical Nurse jobs in Iowa are concentrated in hospital systems, long-term care facilities, and outpatient clinics, with steady demand from entry-level staff nurses through senior clinical roles. The heaviest hiring is in Des Moines, Iowa City, and Cedar Rapids, where established employers like UnityPoint Health, University of Iowa Hospitals and Clinics, and Mercy Medical Center consistently post openings. Medical-surgical, critical care, and behavioral health are among the most in-demand specialties statewide. Find a role that fits below and apply directly.

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Overview

Open roles13
Top employerUnityPoint Health
Top cityDes Moines, IA
Cities hiring9
Work type100% On-site
Top industryHealthcare

Showing 5 of 13+ Clinical Nurse jobs

Clinical Nurse Manager - Full Time
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Added 6d ago
Clinical Nurse Manager - Full Time
RestorixHealth
Carroll, Iowa
Project Management
Software Engineering
Technical Product & Program Management
Managed Registered Nurses (RNs)
1,001-5,000

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Clinical Assistant (Registered Nurse / Licensed Practical Nurse/Certified Medical Assistant)
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Added 2w ago
Clinical Assistant (Registered Nurse / Licensed Practical Nurse/Certified Medical Assistant)
Iowa Kidney Physicians, P.C.
Des Moines, Iowa
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$24 - $39.5/hr
On-Site
CPR Certification

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PRN Clinical Support Nurse (CMA, LPN, or RN)
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Added 2w ago
PRN Clinical Support Nurse (CMA, LPN, or RN)
Magnolia Connection, PC
Ames, Iowa
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$33 - $37/hr
On-Site

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Nurse Clinical Coordinator 100% - UIHC Infusion Clinic Des Moines Area
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Added 1mo ago
Nurse Clinical Coordinator 100% - UIHC Infusion Clinic Des Moines Area
The University of Iowa
Des Moines, Iowa
Customer Service
Customer Support
Hospitality & Guest Services
$59k - $107k/yr
On-Site
Managed Registered Nurses (RNs)
10,000+

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Clinical Nurse Supervisor/Nurse Educator
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Added 1mo ago
Clinical Nurse Supervisor/Nurse Educator
GREENE COUNTY MEDICAL CENTER
Jefferson, Iowa
Higher Education
K-12 Teaching
Teaching & Instruction
Managed Registered Nurses (RNs)
201-500

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See All 13 Clinical Nurse Jobs in Iowa

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Clinical Nurse Jobs by City in Iowa

Where Iowa roles are concentrated, by current openings.

Des Moines
3 jobs
Iowa City
2 jobs
Sioux City
2 jobs
Ames
1 job
Carroll
1 job
Dubuque
1 job
Waterloo
1 job
Jefferson
1 job
Cedar Rapids
1 job

Clinical Nurse Job Market in Iowa

A snapshot from current Iowa openings, updated as new roles post.

Who's Hiring

UnityPoint Health3 open roles
The University of Iowa2 open roles
RestorixHealth1 open role

Top Industries Hiring

  • Healthcare & Medical Services

What Iowa Employers Look For

The qualifications that appear most often in clinical nurse jobs across Iowa.

  • Active RN license issued or recognized by the Iowa Board of Nursing
  • Associate or Bachelor of Science in Nursing degree from an accredited program
  • Current BLS certification required prior to start date
  • One or more years of clinical nursing experience in a hospital or healthcare setting
  • Strong documentation skills and proficiency with electronic health record systems
  • Ability to work rotating shifts including nights, weekends, and holidays as assigned

Clinical Nurse Jobs in Iowa: Frequently Asked Questions

How do you become a clinical nurse in Iowa?

You become a clinical nurse in Iowa by completing an accredited Associate Degree in Nursing or Bachelor of Science in Nursing program, then passing the NCLEX-RN examination. The Iowa Board of Nursing issues and governs RN licensure in the state. Iowa participates in the Nurse Licensure Compact, so nurses licensed in other compact states can practice in Iowa without obtaining a separate state license.

How much do clinical nurses make in Iowa?

Clinical nurses in Iowa earn a median of about $78,630 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,840 for the lowest 10% to over $100,500 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical nurses in Iowa?

Companies currently hiring clinical nurses in Iowa include UnityPoint Health, The University of Iowa, and RestorixHealth, per current listings on Migrate Mate as of October 2026. Iowa's largest health systems and regional medical centers drive the bulk of consistent clinical nurse hiring across the state.

Which Iowa cities have the most clinical nurse jobs?

Des Moines, Iowa City, and Sioux City have the most clinical nurse openings in Iowa. Des Moines anchors the market as the state's largest metro, home to major health systems like UnityPoint Health and MercyOne, while Iowa City benefits from the concentration of clinical activity around University of Iowa Hospitals and Clinics, and Cedar Rapids supports a substantial base of regional hospital and specialty care employment.

Are there remote clinical nurse jobs in Iowa?

Yes, but they're rare. Clinical nursing is a hands-on, patient-facing role, so the vast majority of positions require on-site work in a hospital, clinic, or care facility. About 0% of clinical nurse openings tied to Iowa are remote or hybrid as of October 2026, and those tend to be in telephonic triage, care management, or utilization review functions rather than direct bedside care.

How can I get hired as a clinical nurse in Iowa with little or no experience?

The most realistic entry path is applying to a nurse residency program, which Iowa's largest health systems run specifically for new graduates. UnityPoint Health and University of Iowa Hospitals and Clinics offer structured residency tracks that pair new RNs with experienced preceptors in med-surg or general medical units. Candidates who have worked as certified nursing assistants or patient care technicians hold a practical advantage, and holding an active Iowa RN license before applying shortens the time to hire considerably.

Where can I find and apply to clinical nurse jobs in Iowa?

You can find and apply to clinical nurse jobs in Iowa on Migrate Mate, which lists current Iowa openings across hospital systems, outpatient clinics, and long-term care facilities. Search the listings, find roles that fit your specialty and schedule, and apply directly to each employer through the posting.

See All 13 Clinical Nurse Jobs in Iowa

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