Clinical Nurse Jobs in Iowa

Clinical Nurse jobs in Iowa are concentrated in hospital systems, long-term care facilities, and outpatient clinics, with steady demand from entry-level staff nurses through senior clinical roles. The heaviest hiring is in Des Moines, Iowa City, and Cedar Rapids, where established employers like UnityPoint Health, University of Iowa Hospitals and Clinics, and Mercy Medical Center consistently post openings. Medical-surgical, critical care, and behavioral health are among the most in-demand specialties statewide. Find a role that fits below and apply directly.

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Overview

Open roles28
Top employerUnityPoint Health
Top cityIowa City, IA
Cities hiring14
Work type86% On-site
Top industryHealthcare

Showing 5 of 28+ Clinical Nurse jobs

The University of Iowa
Nurse Clinical Coordinator - UI Health Care Urbandale Infusion Clinic 100%
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The University of Iowa
New 15h ago
Nurse Clinical Coordinator - UI Health Care Urbandale Infusion Clinic 100%
The University of Iowa
Urbandale, Iowa
Project Management
Solutions Engineering & Architecture
Technical Product & Program Management
$59k - $107k/yr
On-Site
Managed Registered Nurses (RNs)
10,000+

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MercyOne
RN - Clinical Specialist Registered Nurse - Clinical / Professional Development
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MercyOne
Added 1w ago
RN - Clinical Specialist Registered Nurse - Clinical / Professional Development
MercyOne
Dubuque, Iowa
Executive Leadership & C-Suite
Program Management
Project Management
Master's degree in nursing

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Naven Health, Inc
Clinical Care Transition Educator / Registered Nurse - Per Diem - Iowa City
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Naven Health, Inc
Added 1w ago
Clinical Care Transition Educator / Registered Nurse - Per Diem - Iowa City
Naven Health, Inc
Iowa City, Iowa
Customer Service
Customer Support
Hospitality & Guest Services
$36.89 - $61.49/hr
1,001-5,000

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MercyOne
Clinical Specialist Registered Nurse
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MercyOne
Added 1w ago
Clinical Specialist Registered Nurse
MercyOne
Dubuque, Iowa
Nursing
Healthcare Administration
Corporate Training & Learning Development
On-Site
Master's

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UnityPoint Health
As Needed* Clinical Nurse - RN - Sunnybrook Urgent Care
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UnityPoint Health
Added 1w ago
As Needed* Clinical Nurse - RN - Sunnybrook Urgent Care
UnityPoint Health
Sioux City, Iowa
Healthcare Administration
Nursing
Patient Services & Wellbeing
10,000+

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Clinical Nurse Jobs by City in Iowa

Where Iowa roles are concentrated, by current openings.

Iowa City
6 jobs
Des Moines
4 jobs
Dubuque
3 jobs
Sioux City
3 jobs
Ames
2 jobs
Cedar Rapids
2 jobs
Solon
1 job
Norwalk
1 job
Waterloo
1 job

Clinical Nurse Job Market in Iowa

A snapshot from current Iowa openings, updated as new roles post.

Who's Hiring

  • UnityPoint Health
    UnityPoint Health10
  • The University of Iowa
    The University of Iowa5
  • MercyOne
    MercyOne2
  • Option Care Health
    Option Care Health2
  • U
    UIHC1

Top Industries Hiring

  • Healthcare & Medical Services
  • Education
  • Biotechnology & Pharmaceuticals

What Iowa Employers Look For

The qualifications that appear most often in clinical nurse jobs across Iowa.

  • Active RN license issued or recognized by the Iowa Board of Nursing
  • Associate or Bachelor of Science in Nursing degree from an accredited program
  • Current BLS certification required prior to start date
  • One or more years of clinical nursing experience in a hospital or healthcare setting
  • Strong documentation skills and proficiency with electronic health record systems
  • Ability to work rotating shifts including nights, weekends, and holidays as assigned

Clinical Nurse Jobs in Iowa: Frequently Asked Questions

How do you become a clinical nurse in Iowa?

You become a clinical nurse in Iowa by completing an accredited Associate Degree in Nursing or Bachelor of Science in Nursing program, then passing the NCLEX-RN examination. The Iowa Board of Nursing issues and governs RN licensure in the state. Iowa participates in the Nurse Licensure Compact, so nurses licensed in other compact states can practice in Iowa without obtaining a separate state license.

How much do clinical nurses make in Iowa?

Clinical nurses in Iowa earn a median of about $78,630 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,840 for the lowest 10% to over $100,500 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical nurses in Iowa?

Companies currently hiring clinical nurses in Iowa include UnityPoint Health, The University of Iowa, and MercyOne, per current listings on Migrate Mate as of August 2026. Iowa's largest health systems and regional medical centers drive the bulk of consistent clinical nurse hiring across the state.

Which Iowa cities have the most clinical nurse jobs?

Iowa City, Des Moines, and Dubuque have the most clinical nurse openings in Iowa. Des Moines anchors the market as the state's largest metro, home to major health systems like UnityPoint Health and MercyOne, while Iowa City benefits from the concentration of clinical activity around University of Iowa Hospitals and Clinics, and Cedar Rapids supports a substantial base of regional hospital and specialty care employment.

Are there remote clinical nurse jobs in Iowa?

Yes, but they're rare. Clinical nursing is a hands-on, patient-facing role, so the vast majority of positions require on-site work in a hospital, clinic, or care facility. About 14% of clinical nurse openings tied to Iowa are remote or hybrid as of August 2026, and those tend to be in telephonic triage, care management, or utilization review functions rather than direct bedside care.

How can I get hired as a clinical nurse in Iowa with little or no experience?

The most realistic entry path is applying to a nurse residency program, which Iowa's largest health systems run specifically for new graduates. UnityPoint Health and University of Iowa Hospitals and Clinics offer structured residency tracks that pair new RNs with experienced preceptors in med-surg or general medical units. Candidates who have worked as certified nursing assistants or patient care technicians hold a practical advantage, and holding an active Iowa RN license before applying shortens the time to hire considerably.

Where can I find and apply to clinical nurse jobs in Iowa?

You can find and apply to clinical nurse jobs in Iowa on Migrate Mate, which lists current Iowa openings across hospital systems, outpatient clinics, and long-term care facilities. Search the listings, find roles that fit your specialty and schedule, and apply directly to each employer through the posting.

See All 28 Clinical Nurse Jobs in Iowa

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