Clinical Project Manager Jobs in California
Clinical Project Manager jobs in California are among the most active in the country, concentrated in the life sciences, biotech, and pharmaceutical sectors that define the state's economy, with openings at every level from associate clinical project manager through senior and program director. The heaviest hiring is in the San Francisco Bay Area, San Diego, and Los Angeles, where employers like Genentech, AstraZeneca, and Kaiser Permanente maintain major operations. Oncology trials, rare disease programs, and biologics development generate the most consistent demand for clinical project managers statewide. Find a role that fits below and apply directly.
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Showing 5 of 33+ Clinical Project Manager jobs
Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn , X (Twitter) and Facebook .
The Clinical Laboratory Scientist is responsible for performing high complexity laboratory testing (Next generation DNA sequencing) on patient specimens, performing quality control and quality assurance procedures, interpreting and reporting patient results, and complying with all applicable local, state and federal laboratory requirements. The work requires keeping meticulous and organized records, excellent attention to detail, the ability to multi-task, and be flexible with tasks and schedules.
Shift Details: Thursday-Monday; PM Shift 2:30pm-11pm PT
Essential Duties and Responsibilities:
- Perform laboratory tests, procedures and analyses per the laboratory’s standard operating procedures
- Review, interpret and report patient results in LIMS
- Independently identify and troubleshoot high complexity problems that adversely affect the test performance
- Perform, review and document laboratory quality control procedures
- Document all corrective actions taken when test systems deviate from the laboratory’s established performance specifications
- Perform and document routine preventive maintenance
- Assist with training of new laboratory personnel
- Maintain sufficient inventory of laboratory supplies for daily operations and prepare reagents required for testing
- Perform and document reagent qualification per the approved protocols
- Perform annual review of Standard Operating Procedures
- Report all concerns of test quality and/or safety to the Laboratory Supervisor or Safety Officer
- Participate in introduction of assay improvements, new assay configurations and validation
- Perform other miscellaneous laboratory duties as assigned and assist others as time allows
Qualifications:
EDUCATION AND EXPERIENCE
- California Clinical Laboratory Scientist Generalist license
- Bachelor of Arts or Science in Biomedical Laboratory Science, Clinical Science or related field
- Working knowledge of local, state, and federal laboratory regulations
- Able to integrate and apply feedback in a professional manner
- Able to prioritize and drive to results with a high emphasis on quality
- Ability to work as part of a team
PHYSICAL DEMANDS/WORKING ENVIRONMENT
- Hours and days may vary depending on operational needs
- Standing or sitting for long periods of time may be necessary.
- May be exposed to hazardous materials, blood specimens and instruments with moving parts, heating or freezing elements, and high speed centrifugation (Generally Laboratory and Client Services employees only)
- Repetitive manual pipetting may be necessary Some lifting (up to 25 pounds) may be necessary
AI & Digital Fluency
Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI-enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work.
Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com
A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants .
Please visit our career page at: http://www.guardanthealth.com/jobs/
Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn , X (Twitter) and Facebook .
The Clinical Laboratory Scientist is responsible for performing high complexity laboratory testing (Next generation DNA sequencing) on patient specimens, performing quality control and quality assurance procedures, interpreting and reporting patient results, and complying with all applicable local, state and federal laboratory requirements. The work requires keeping meticulous and organized records, excellent attention to detail, the ability to multi-task, and be flexible with tasks and schedules.
Shift Details: Thursday-Monday; PM Shift 2:30pm-11pm PT
Essential Duties and Responsibilities:
- Perform laboratory tests, procedures and analyses per the laboratory’s standard operating procedures
- Review, interpret and report patient results in LIMS
- Independently identify and troubleshoot high complexity problems that adversely affect the test performance
- Perform, review and document laboratory quality control procedures
- Document all corrective actions taken when test systems deviate from the laboratory’s established performance specifications
- Perform and document routine preventive maintenance
- Assist with training of new laboratory personnel
- Maintain sufficient inventory of laboratory supplies for daily operations and prepare reagents required for testing
- Perform and document reagent qualification per the approved protocols
- Perform annual review of Standard Operating Procedures
- Report all concerns of test quality and/or safety to the Laboratory Supervisor or Safety Officer
- Participate in introduction of assay improvements, new assay configurations and validation
- Perform other miscellaneous laboratory duties as assigned and assist others as time allows
Qualifications:
EDUCATION AND EXPERIENCE
- California Clinical Laboratory Scientist Generalist license
- Bachelor of Arts or Science in Biomedical Laboratory Science, Clinical Science or related field
- Working knowledge of local, state, and federal laboratory regulations
- Able to integrate and apply feedback in a professional manner
- Able to prioritize and drive to results with a high emphasis on quality
- Ability to work as part of a team
PHYSICAL DEMANDS/WORKING ENVIRONMENT
- Hours and days may vary depending on operational needs
- Standing or sitting for long periods of time may be necessary.
- May be exposed to hazardous materials, blood specimens and instruments with moving parts, heating or freezing elements, and high speed centrifugation (Generally Laboratory and Client Services employees only)
- Repetitive manual pipetting may be necessary Some lifting (up to 25 pounds) may be necessary
AI & Digital Fluency
Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI-enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work.
Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com
A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants .
Please visit our career page at: http://www.guardanthealth.com/jobs/
See All 33 Clinical Project Manager Jobs in California
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Find Clinical Project Manager JobsClinical Project Manager Jobs by City in California
Where California roles are concentrated, by current openings.
Clinical Project Manager Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring
What California Employers Look For
The qualifications that appear most often in clinical project manager jobs across California.
- Bachelor's degree in life sciences, nursing, or a related clinical or scientific field
- PMP or CAPM certification strongly preferred by most California employers
- Minimum two to five years of clinical trial management or CRO experience
- Working knowledge of ICH-GCP guidelines and FDA regulatory requirements
- Proficiency with clinical trial management systems such as Veeva or Medidata Rave
- Strong cross-functional communication skills for managing sites and sponsor relationships
Clinical Project Manager Jobs in California: Frequently Asked Questions
How do you become a clinical project manager in California?
The most direct path is a bachelor's degree in a life sciences or clinical field followed by experience in clinical operations, data management, or regulatory affairs. California does not require a state-issued license specific to clinical project management, but most employers expect PMP or CAPM certification alongside hands-on clinical trial experience. Many candidates move into the role from clinical research associate or clinical trial coordinator positions at California biotech companies, academic medical centers, or contract research organizations.
How much do clinical project managers make in California?
Clinical project managers in California earn a median of about $120,910 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $69,180 for the lowest 10% to over $188,560 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinical project managers in California?
Employers hiring clinical project managers in California right now include Success Education Colleges, PIH Health, and CenExel Clinical Research, based on current listings on Migrate Mate as of September 2026. California's dense concentration of biotech headquarters and large integrated health systems means openings appear consistently across both established pharmaceutical companies and high-growth clinical-stage firms.
Which California cities have the most clinical project manager jobs?
The cities with the most clinical project manager openings in California are California, San Diego, and West Covina. The Bay Area and San Diego drive the largest share of postings because of their dense clusters of biotech and pharmaceutical headquarters, while Los Angeles openings tend to come from large hospital systems and medical device companies with significant clinical programs.
Are there remote clinical project manager jobs in California?
Yes, and more than most clinical roles. Because clinical project managers coordinate rather than deliver direct patient care, a meaningful portion of the work can be done remotely. About 60% of clinical project manager openings tied to California are remote or hybrid as of September 2026, reflecting how the role has shifted since decentralized trial models became standard. Sponsor-side roles and those focused on data oversight and vendor management are the most likely to offer full remote flexibility.
How can I get hired as a clinical project manager in California with little or no experience?
The most realistic entry path is starting as a clinical research associate or clinical trial coordinator, roles that California CROs and biotech companies hire for regularly and that build directly transferable skills. Large employers in the Bay Area and San Diego, including contract research organizations with California offices, run associate CRA and trial coordinator development programs designed for candidates with a life sciences degree and limited field experience. Earning a CAPM certification and gaining protocol exposure through academic medical centers or community oncology sites strengthens a candidate's profile considerably.
Where can I find and apply to clinical project manager jobs in California?
You can find and apply to clinical project manager jobs in California on Migrate Mate, which lists current openings tied to the California market. Search the listings to find roles that match your experience level, specialty area, and preferred location, then apply directly to the ones that fit.
See All 33 Clinical Project Manager Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
Find Clinical Project Manager Jobs