Clinical Project Manager Jobs in Illinois
Clinical Project Manager jobs in Illinois are in strong demand, with openings concentrated in pharmaceutical development, medical device manufacturing, contract research, and academic medical centers, and roles available from entry-level coordinators through senior and principal-level managers. Chicago anchors the bulk of hiring, alongside the suburban corridor stretching through Deerfield and Lake County, where established employers like AbbVie, Takeda, and Northwestern Medicine maintain deep clinical operations teams. The most sought-after specialties in Illinois include oncology trial management, regulatory affairs-aligned project oversight, and Phase II-IV trial coordination. Find a role that fits below and apply directly.
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See related jobsVoted one of Chicago's Best Places to Work by the Chicago Tribune for the ninth year in a row, Clarity Partners is hiring!
Clarity Partners is seeking an Epic Applications & Project Manager to provide dedicated leadership and oversight for one track of our client's Epic inpatient clinical application portfolio. In this role, you will lead application build, clinical workflows, testing, dependencies, readiness, go-live, and transition to ongoing operations for your assigned track — either the inpatient orders and pharmacy/inventory systems, or the emergency and inpatient clinical documentation systems. This is a full-time opportunity on a large-scale client facing project.
Responsibilities
- Lead Epic application build and configuration decisions for the assigned application track.
- Lead clinical and, where applicable, medication workflow design and validation sessions
- Direct testing activities (unit, integration, end-to-end) across the assigned applications.
- Manage cross-application and cross-team dependencies through the implementation timeline.
- Lead go-live readiness assessments and go-live execution for the assigned track.
- Own the transition from go-live support into ongoing operations.
Requirements
- Bachelor’s degree in information technology, Computer Science, Healthcare Administration, Pharmacy, Clinical Informatics, Business, or a related field required; equivalent progressively responsible experience may be considered.
- Minimum of 7 years of progressively responsible healthcare IT experience, including significant experience implementing and supporting clinical applications.
- Recent, hands-on experience leading Epic implementations within academic medical centers, safety-net hospitals, large integrated health systems, or similarly complex healthcare environments required.
- Current or very recent experience leading Epic application and technical teams through the full implementation lifecycle, including design, workflow and build decisions, testing, readiness, cutover, go-live, and stabilization.
-
Background in at least one of the following application tracks required:
- Track A – Inpatient Orders & Pharmacy: EpicCare Inpatient Orders, Willow Inpatient Pharmacy, and Willow Inpatient Inventory
- Track B – Emergency & Clinical Documentation: Epic ASAP and EpicCare Inpatient Clinical Documentation
- Direct experience with the Epic applications in the assigned track strongly preferred.
- Strong understanding of inpatient, pharmacy, and emergency department workflows, healthcare operations, and the technical and operational considerations of enterprise EHR implementations.
- Proven ability to lead large, cross-functional teams and manage relationships with executive-level clinical, operational, and IT stakeholders.
- Experience managing complex project budgets, implementation schedules, staffing plans, vendors, and subcontractors, along with strong organizational change management and end-user adoption experience.
- Excellent written, verbal, presentation, and executive communication skills, including the ability to translate complex technical concepts for clinical and business audiences.
- Epic certification or accreditation in a relevant application area preferred; ability to obtain required Epic certification or accreditation within established program timelines required.
- PMP or comparable project management certification preferred.
- Experience working with public health systems, safety-net institutions, or county or government healthcare organizations preferred.
- Previous experience in a consulting or staff augmentation environment preferred.
Clarity is committed to fair and equitable compensation practices. For the Epic Applications & Project Manager, the base salary pay range is $125,000 - $145,000. The range represents a good faith estimate that Clarity reasonably expects to pay for this job at the time of posting. Compensation will depend upon an individual's skills, experience, qualifications, location, and other relevant factors. The salary pay range is subject to change and may be modified at any time.
Voted one of Chicago's Best Places to Work by the Chicago Tribune for the ninth year in a row, Clarity Partners is hiring!
Clarity Partners is seeking an Epic Applications & Project Manager to provide dedicated leadership and oversight for one track of our client's Epic inpatient clinical application portfolio. In this role, you will lead application build, clinical workflows, testing, dependencies, readiness, go-live, and transition to ongoing operations for your assigned track — either the inpatient orders and pharmacy/inventory systems, or the emergency and inpatient clinical documentation systems. This is a full-time opportunity on a large-scale client facing project.
Responsibilities
- Lead Epic application build and configuration decisions for the assigned application track.
- Lead clinical and, where applicable, medication workflow design and validation sessions
- Direct testing activities (unit, integration, end-to-end) across the assigned applications.
- Manage cross-application and cross-team dependencies through the implementation timeline.
- Lead go-live readiness assessments and go-live execution for the assigned track.
- Own the transition from go-live support into ongoing operations.
Requirements
- Bachelor’s degree in information technology, Computer Science, Healthcare Administration, Pharmacy, Clinical Informatics, Business, or a related field required; equivalent progressively responsible experience may be considered.
- Minimum of 7 years of progressively responsible healthcare IT experience, including significant experience implementing and supporting clinical applications.
- Recent, hands-on experience leading Epic implementations within academic medical centers, safety-net hospitals, large integrated health systems, or similarly complex healthcare environments required.
- Current or very recent experience leading Epic application and technical teams through the full implementation lifecycle, including design, workflow and build decisions, testing, readiness, cutover, go-live, and stabilization.
-
Background in at least one of the following application tracks required:
- Track A – Inpatient Orders & Pharmacy: EpicCare Inpatient Orders, Willow Inpatient Pharmacy, and Willow Inpatient Inventory
- Track B – Emergency & Clinical Documentation: Epic ASAP and EpicCare Inpatient Clinical Documentation
- Direct experience with the Epic applications in the assigned track strongly preferred.
- Strong understanding of inpatient, pharmacy, and emergency department workflows, healthcare operations, and the technical and operational considerations of enterprise EHR implementations.
- Proven ability to lead large, cross-functional teams and manage relationships with executive-level clinical, operational, and IT stakeholders.
- Experience managing complex project budgets, implementation schedules, staffing plans, vendors, and subcontractors, along with strong organizational change management and end-user adoption experience.
- Excellent written, verbal, presentation, and executive communication skills, including the ability to translate complex technical concepts for clinical and business audiences.
- Epic certification or accreditation in a relevant application area preferred; ability to obtain required Epic certification or accreditation within established program timelines required.
- PMP or comparable project management certification preferred.
- Experience working with public health systems, safety-net institutions, or county or government healthcare organizations preferred.
- Previous experience in a consulting or staff augmentation environment preferred.
Clarity is committed to fair and equitable compensation practices. For the Epic Applications & Project Manager, the base salary pay range is $125,000 - $145,000. The range represents a good faith estimate that Clarity reasonably expects to pay for this job at the time of posting. Compensation will depend upon an individual's skills, experience, qualifications, location, and other relevant factors. The salary pay range is subject to change and may be modified at any time.
See All 5 Clinical Project Manager Jobs in Illinois
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Find Clinical Project Manager JobsClinical Project Manager Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Clinical Project Manager Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring
What Illinois Employers Look For
The qualifications that appear most often in clinical project manager jobs across Illinois.
- Bachelor's degree in life sciences, nursing, or a related clinical field required
- PMP or CAPM certification preferred or required by most Illinois employers
- Minimum two to five years of clinical trial or research project management experience
- Proficiency with clinical trial management systems such as Veeva Vault or Medidata Rave
- Working knowledge of ICH-GCP guidelines and FDA regulatory requirements
- Strong stakeholder communication skills for cross-functional site and vendor coordination
Clinical Project Manager Jobs in Illinois: Frequently Asked Questions
How do you become a clinical project manager in Illinois?
The most direct path is a bachelor's degree in a life science, nursing, or health administration field followed by experience in clinical research coordination or trial operations. Illinois does not require a state-issued license specific to clinical project managers, but employers strongly favor candidates who hold the Project Management Professional credential through the Project Management Institute or the Clinical Research Associate certification through the Association of Clinical Research Professionals. Building experience within Illinois's large academic medical centers or CROs accelerates the transition into a full project management role.
How much do clinical project managers make in Illinois?
Clinical project managers in Illinois earn a median of about $103,470 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $65,300 for the lowest 10% to over $163,910 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinical project managers in Illinois?
Employers hiring clinical project managers in Illinois right now include Endeavor Health, Clarity Partners, and Humboldt Park Health, based on current listings on Migrate Mate as of November 2026. Illinois's concentration of global pharmaceutical headquarters, contract research organizations, and major academic health systems means the hiring pipeline is consistently active, particularly in the northern suburbs and the Chicago medical district.
Which Illinois cities have the most clinical project manager jobs?
Chicago, Illinois, and Naperville have the most clinical project manager openings in Illinois. Chicago leads because of its academic medical centers, hospital networks, and regional CRO offices, while the Lake County and North Shore suburbs draw significant volume from pharmaceutical and biotech headquarters such as AbbVie and Takeda that run large global clinical teams from those locations.
Are there remote clinical project manager jobs in Illinois?
Yes, and more than most clinical roles. Because clinical project managers handle trial oversight, vendor coordination, and documentation rather than direct patient care, a meaningful share of the work can be done remotely. About 100% of clinical project manager openings tied to Illinois are remote or hybrid as of November 2026, reflecting the desk-based and digital nature of much of the role. Site monitoring responsibilities and sponsor kick-off meetings still pull many positions toward hybrid schedules.
How can I get hired as a clinical project manager in Illinois with little or no experience?
Starting as a clinical research coordinator or trial assistant is the most realistic entry point, and Illinois offers strong opportunities through Northwestern Medicine, Rush University Medical Center, and the University of Chicago Medicine, all of which run structured research programs that bring in coordinators at the associate level. Earning a Clinical Research Coordinator credential early and volunteering on IRB-approved studies through Illinois academic institutions builds the portfolio that Illinois hiring managers look for when promoting into project management roles.
Where can I find and apply to clinical project manager jobs in Illinois?
You can find and apply to clinical project manager jobs in Illinois on Migrate Mate, which lists current Illinois openings across pharmaceutical companies, contract research organizations, hospital systems, and medical device firms. Find the roles that fit your experience and specialization and apply directly from the listings below.
See All 5 Clinical Project Manager Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
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