Clinical Project Manager Jobs in Minnesota

We anticipate the application window for this opening will close on - 6 Jul 2026

At Medtronic you can begin a life-long career of exploration and innovation, while helping champion healthcare access and equity for all. You’ll lead with purpose, breaking down barriers to innovation in a more connected, compassionate world.

A Day in the Life

Peripheral Vascular Health therapies are a critical part of the Medtronic vascular portfolio, treating patients with a broad range of conditions, including Peripheral and Carotid Disease, End Stage Renal Disease, Peripheral Embolization, and Superficial and Deep Venous Disease. We lead the way in the Superficial Venous and Drug Coated Balloon markets, caring for hundreds of millions of patients globally with lifesaving and life-enhancing therapies.

At Medtronic, we bring bold ideas forward with speed and decisiveness to put patients first in everything we do. In-person exchanges are invaluable to our work. We’re working a minimum of 4 days a week onsite as part of our commitment to fostering a culture of professional growth and cross-functional collaboration as we work together to engineer the extraordinary.

This position will be based in Plymouth, MN.

In this exciting role as a Clinical Program Manager (CPM), you will be responsible for leading the development and execution of the global clinical evidence strategy and roadmap for multiple medical device products in the Peripheral Vascular Health portfolio. You will define clinical evidence needs across released and pipeline products, identify evidence gaps, and implement fit-for-purpose strategies to generate data that supports regulatory, clinical, and business objectives. The CPM collaborates with internal and external stakeholders, builds partnerships with key opinion leaders to understand therapy and market needs, and maintains strong knowledge of product applications, relevant anatomy, and clinical use of Medtronic technologies.

Role and Responsibilities

• Plans and oversees clinical research programs from concept through completion
• Develops and maintains detailed project plans, including timelines, budgets, resource allocations, decision logs, risks & mitigations
• Prepares program dashboards to communicate the portfolio status, highlights, risks, mitigations
• Present to, and partner with, clinical and medical science team members and leadership on the overall health of the portfolio, successes, and areas of opportunity
• Interacts and works cross-functionally with (but not limited to) Clinical, Medical Science, Quality, Medical Safety, Regulatory Affairs, Marketing, Market Development, R&D, and regions (US and OUS) to ensure program execution to achieve business goals within regulatory requirements.
• Ensure that clinical trials are conducted in accordance with regulatory requirements, Good Clinical Practice (GCP) guidelines, and company SOPs
• Identifies and leverage innovative real-world data and real-world evidence opportunities to fulfill evidence requirements, optimizing time and costs
• Identifies, builds and maintains meaningful partnerships with key opinion leaders and innovators to understand clinical therapy/market needs from a clinician’s perspective
• Coordinates clinical evidence strategies with other cross-functions to ensure robust CRMS strategy
• Serves as Core Team representative:
• Provides clinical subject matter expertise (SME) and CRMS representation on various technology development (pre-PDP), product development (PDP), continued development (CDP) and remediation projects
• Leverages competitive intelligence around clinical/regulatory pathways, indications and labeling, claims, clinical evidence to inform and execute on differentiated and market leading evidence that support business stakeholders
• Determines burden of evidence for our products and partners with core team stakeholders to develop innovative clinical development plans to ensure timely product launch in target regions and market access and adoption
• Involved in changes to systems/products and what may be required to support this from a clinical perspective
• Keeps current on over-arching core team project priorities and deliverables
• Clinical Study Support and Oversight:
• Provides input into clinical investigation documents to ensure alignment with overall business strategy, including: Protocols, Case Report Forms, Informed Consent Forms, Clinical Study Reports etc.
• May lead document development and execution of studies
• Interprets and ensures dissemination of results of clinical investigations in preparation for new device or supporting application
• Works with statistical team on analysis of data from MDT-internal and external databases, as appropriate
• Leads cross-functional project teams
• Facilitates communication and collaboration among team members, stakeholders, and external partners
• Provide regular updates to senior management and cross-functional leaders on project status, risks, and issues
• Regulatory Compliance and Engagement:
• Ensures that all clinical research activities comply with applicable regulatory requirements and ethical standards
• May prepare and submit regulatory documents, including protocols, informed consent forms, and progress reports
• May coordinate with regulatory authorities and ethics committees to obtain necessary approvals
• Provides input and review, as appropriate, clinical evaluation documents to ensure alignment with overall product MDR strategy, including: Clinical Evidence Plan (CEP), PMCF plan, PMCF report, Clinical Evaluation Report (CER)
• Risk management file and IFU development
• Supports global regulatory submissions
• Data and Results Interpretation:
• Oversees data collection, management, and analysis to ensure accuracy and integrity
• Works with data management and biostatistics teams to develop data management plans and statistical analysis plans
• Ensures timely and accurate reporting of study results
• Drives the global publication and evidence dissemination strategy through close collaborations with Medical Science, healthcare economics, global portfolio and marketing functions
• Budget Management:
• Performs financial budget modeling and scenario planning around evidence needs
• Advocates for appropriate support and funding for highest priority projects, in conjunction with cross-functional evidence team
• Develops and manages program budgets, including forecasting and tracking expenses
• Ensures that projects are completed within budget and on schedule
• Identifies and mitigates financial risks

Additional Responsibilities:

• Builds and maintains a strong network and close relationship with the various internal and external parties.
• Maintains strong understanding of product knowledge, relevant anatomy, and accepted applications and uses associated with our products
• Utilizes subject matter expertise to provide clinical input to various functions (General Management, Global Strategy & Portfolio Management, Business Development & Licensing, Research & Development, & Marketing) and organizational units to facilitate insightful decision-making and enable achievement of business objectives.
• Critically evaluates due diligence information for inorganic opportunities
• Understands that needs and funding will change over time
• Effective leadership and team facilitation skills to motivate cross-functional and cross-business unit partners to work towards common clinical evidence goals
• Assesses project issues and develops resolutions
• Develops mechanisms for monitoring project progress and for intervention and problem solving
• Understands the market and competitive space
• Provides marketing material review for clinical evidence claims as needed
• Provides scientific input for evidence generation including sponsored research, ERPs, Scientific Services, Collaborative Research and Alternative Data Source projects

Must Have (Minimum Requirements):

To be considered for this role, please ensure the minimum requirements are evident in your applicant profile.

• Bachelor's degree with 5+ years of experience in clinical research/clinical strategy in the healthcare industry
• Or an advanced degree with 3+ years of experience in clinical research/clinical strategy in the healthcare industry

Nice To Have

• Degree in engineering, life sciences, or related medical/scientific field
• Clinical research/clinical trials experience at Medtronic or within a medical device industry
• Experience in clinical operations
• Experience developing clinical strategies and study design
• Experience in Peripheral or Endovenous therapies/product
• Experience working on a global study team
• Basic understanding of biostatistics and trial design
• Experience in Research and Development (R&D)
• Project/program management skills/experience
• Ability to appropriately apply different standards related to medical devices/clinical research (SOPs, GCP, ISO, ICH, FDA, MEDDEV, MDR, etc.) as needed
• Proficiency in MS Office applications: Excel, PowerPoint and Word, Project (or similar scheduling software), project management techniques and tools; and web-based applications
• PMP certification; Project Management Certification (preferably PMI) and/or Green Belt Certification
• Thrives in a dynamic environment and flexibility to adapt to changing priorities

For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required.

Physical Job Requirements

The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.

The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role.

U.S. Work Authorization & Sponsorship

At Medtronic, we are committed to fostering an environment where employees can thrive and make a meaningful impact. In alignment with our enterprise-wide workforce planning approach, U.S. work authorization sponsorship (H-1B, TN, J, etc.) is offered exclusively for Principal-level roles and above, where specialized expertise aligns with long-term business needs. Roles below the Principal level require candidates to possess unrestricted U.S. work authorization at the time of hire and for the duration of employment.

Join us in our mission to alleviate pain, restore health, and extend life—where your unique background and perspective are valued.

Benefits & Compensation

Medtronic offers a competitive Salary and flexible Benefits Package

A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create. We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage.

Salary ranges for U.S (excl. PR) locations (USD): $132,800.00 - $199,200.00

This position is eligible for a short-term incentive called the Medtronic Incentive Plan (MIP). The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others). The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance, Health Savings Account, Healthcare Flexible Spending Account, Life insurance, Long-term disability leave, Dependent daycare spending account, Tuition assistance/reimbursement, and Simple Steps (global well-being program).

The following benefits and additional compensation are available to all regular employees: Incentive plans, 401(k) plan plus employer contribution and match, Short-term disability, Paid time off, Paid holidays, Employee Stock Purchase Plan, Employee Assistance Program, Non-qualified Retirement Plan Supplement (subject to IRS earning minimums), and Capital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums).

Regular employees are those who are not temporary, such as interns. Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico.

Further details are available at the link below:

Medtronic benefits and compensation plans

About Medtronic

We lead global healthcare technology and boldly attack the most challenging health problems facing humanity by searching out and finding solutions.

Our Mission — to alleviate pain, restore health, and extend life — unites a global team of 95,000+ passionate people.

We are engineers at heart—putting ambitious ideas to work to generate real solutions for real people. From the R&D lab, to the factory floor, to the conference room, every one of us experiments, creates, builds, improves and solves. We have the talent, diverse perspectives, and guts to engineer the extraordinary.

It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities.

If you are applying to perform work for Medtronic, Inc. (“Medtronic”) in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.