Clinical Research Jobs in North Carolina
Clinical Research jobs in North Carolina are concentrated in pharmaceutical development, academic medical research, and contract research organizations, with openings at every level from clinical research coordinator to principal investigator. The heaviest hiring activity is in the Research Triangle Park area, Charlotte, and Greensboro, anchored by institutions and employers such as Duke University Health System, GlaxoSmithKline, and PPD. The most in-demand specialties include oncology trials, cardiovascular studies, and regulatory affairs coordination. Find a role that fits below and apply directly.
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NC Retina Associates is looking for a Research Assistant to join our team! The research assistant is primarily responsible for assisting in research patient visits according to International Council for Harmonisation Good Clinical Practice (ICH-GCP) guidelines and according to the Institutional Review Board (IRB)-approved study protocol and/or manual of procedures.
Duties:
- Coordinate and schedule subject visits within study/subject specific windows per protocol guidelines.
- Prepare visit-specific documentation and charts for Clinical Research Coordinator.
- Observe Coordinator in patient care and management.
- Assist Coordinator in monitoring subject flow and assist in subject care and management.
- Observe, assist, collect and record all necessary data for follow up (e.g. adverse events, concomitant medications, etc.) study visits (Phase 2 & 3; NO Gene Therapy).
- Transcribe subject study information from source documents to the Electronic Case Report Forms.
- Administer all mandatory questionnaires to study subjects.
- Set up, prepare subject, and conduct electrocardiograms (ECG) on subjects as required per study protocol.
- Promptly request all necessary medical records for Serious Adverse Event Reporting.
- Process and ship laboratory biological samples for analysis.
- Perform intraocular pressure checks after injections.
- Perform trial frame refraction and Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity testing (For Investigator Sponsored Trials (IST)s only, at selected sites).
- Inform subjects and obtain written re-consents in regard to Informed Consent Form (ICF)’s (selected studies)
- Observe and assist scribe in ocular exams for doctors and confirm appropriate treatment per protocol.
- Perform other duties as assigned.
- Obtain any applicable additional/required sponsor training and/or certifications.
Minimum Qualifications:
- High School diploma or the equivalent, with significant relevant experience.
- College degree preferred.
- Ophthalmic experience preferred.
- Effective oral and written communication.
- Delivers safe and appropriate care to patients in addition to the requirements outlined by study protocols.
Pay: $23.00 - $28.00 per hour
Expected hours: 35.0 – 40.0 per week
Benefits:
- 401(k)
- 401(k) matching
- Dental insurance
- Health insurance
- Health savings account
- Life insurance
- Paid time off
- Retirement plan
- Vision insurance
Application Question(s):
- Do you have any Ophthalmology or Retina specific study experience?
- Do you currently reside in North Carolina?
Experience:
- Clinical research: 1 year (Required)
Work Location: In person
See All 58 Clinical Research Jobs in North Carolina
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Find Clinical Research JobsClinical Research Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Clinical Research Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Science & Research
- Healthcare & Medical Services
- Staffing & Recruiting
- Biotechnology & Pharmaceuticals
- Consulting & Professional Services
What North Carolina Employers Look For
The qualifications that appear most often in clinical research jobs across North Carolina.
- Bachelor's degree in life sciences, nursing, or a related clinical field
- ACRP or SOCRA certification preferred or required by most North Carolina employers
- Demonstrated experience with ICH-GCP guidelines and federal clinical trial regulations
- Proficiency with electronic data capture systems such as Medidata Rave or REDCap
- Strong documentation and source data verification skills from prior trial coordination
- Familiarity with IRB submission processes and North Carolina institutional review requirements
Clinical Research Jobs in North Carolina: Frequently Asked Questions
How do you become a clinical research professional in North Carolina?
Most clinical research positions in North Carolina require at least a bachelor's degree in a life science, health science, or nursing field, followed by hands-on trial coordination experience. While North Carolina does not issue a state-specific clinical research license, employers widely expect candidates to hold or pursue certification from the Association of Clinical Research Professionals or the Society of Clinical Research Associates. Many coordinators enter through academic medical centers affiliated with UNC Health, Duke Health, or Wake Forest Baptist.
Which companies hire clinical research professionals in North Carolina?
Employers hiring clinical research professionals in North Carolina right now include Thermo Fisher Scientific, University of North Carolina at Chapel Hill, and IQVIA, based on current listings on Migrate Mate as of August 2026. North Carolina's Research Triangle Park corridor hosts a dense cluster of contract research organizations and pharmaceutical sponsors that sustain ongoing demand for trial staff.
Which North Carolina cities have the most clinical research jobs?
The cities with the most clinical research openings in North Carolina are Durham, Raleigh, and North Carolina. The Research Triangle area dominates because of its concentration of pharmaceutical headquarters, contract research organizations headquartered at Research Triangle Park, and major academic medical centers in Durham, Raleigh, and Chapel Hill, while Charlotte's expanding hospital systems drive demand in the western part of the state.
Are there remote clinical research jobs in North Carolina?
Yes, but they are less common than in purely desk-based fields, since most trial roles require on-site patient contact or facility monitoring. About 46% of clinical research openings tied to North Carolina are remote or hybrid as of August 2026. The positions most likely to allow remote work are regulatory affairs roles, data management, medical writing, and sponsor-side clinical monitoring where site visits are scheduled rather than daily.
How can I get hired as a clinical research professional in North Carolina with little or no experience?
The most realistic entry path is a clinical research coordinator role at a large academic medical center, where new-graduate programs and formal coordinator training tracks exist at institutions such as Duke Health, UNC Health, and Atrium Health. Candidates with backgrounds in nursing, pharmacy technician work, or clinical data entry have a natural edge, and earning a ACRP Clinical Research Associate certification before applying strengthens any application significantly in a competitive Research Triangle market.
Where can I find and apply to clinical research jobs in North Carolina?
You can find and apply to clinical research jobs in North Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, find positions that match your experience and preferred location, and apply directly to each one.
See All 58 Clinical Research Jobs in North Carolina
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