Clinical Trial Manager Jobs in Massachusetts
Clinical Trial Manager jobs in Massachusetts are among the most active in the country, concentrated in pharmaceutical development, biotechnology, and academic medical research with openings at every level from entry-level clinical research associate to senior trial manager. Boston, Cambridge, and Worcester are the primary hiring centers, anchored by large employers like Pfizer, Bristol Myers Squibb, and Massachusetts General Hospital. The most in-demand specialties include oncology trials, rare disease studies, and Phase II through Phase IV drug development. Find a role that fits below and apply directly.
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Job Description:
Company Overview
Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world’s first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary
Working closely with the Clinical Trial Manager, the Clinical Trial Associate (CTA) position will assist with daily clinical trial execution activities including the coordination of documents associated with the conduct of investigational clinical studies in accordance with applicable regulations, Good Clinical Practice (GCP), and CRISPR Therapeutics standard operating procedures (SOPs). The ideal candidate will have keen attention to detail and has the ability both to prioritize and independently handle multiple tasks effectively.
This incredible opportunity will put the right candidate at the forefront of medicine, working on ground breaking trials with tremendous potential to impact patient's lives. You will join a team of incredibly dedicated professionals whose talent is matched by their commitment and passion for the work we are doing. A team that remains focused on what's important for the patient and also has an incredible track record of growth and development among them. If you are looking to learn, work hard, and make a difference, we would like to speak with you.
Responsibilities
- Help maintain tracking systems and tools to support the conduct of a clinical study from start-up to close-out
- Collect trial information and disseminate it to the internal project team, the CRO, and other stakeholders
- Coordinate study meetings, materials and agendas; recording and disseminating decisions and actions
- Responsible for internal meeting agendas/minutes as applicable
- Responsible for updating, maintaining and quality control of the eTMF, SharePoint site and shared drive
- Responsible for study laboratory sample tracking and vendor management support
- Coordinate version control of clinical documents, prioritize multiple tasks and/or projects
- Assist in coordination and tracking of clinical supply shipments, including review and approval of Regulatory Greenlight Documentation Packages
- Support Clinical Operations team in new process development or optimization
- Effectively communicate with study team members and work closely to address challenges
Minimum Qualifications
- BS/BA degree or equivalent and at least 1-3+ years experience in clinical research
- Knowledge of drug development, clinical operation processes and documentation including study start up procedures, maintenance phase, and study close out procedures
- Knowledge and implementation of the processes involved in clinical studies following Good Clinical Practice (GCP) and the Code of Federal Regulations
- Experience with eTMF; ability to directly apply essential document knowledge to file documents
- Effective communication, organizational and interpersonal/team skills
- Proficient in MS Excel, Word and PowerPoint.
- Established ability to prioritize and manage multiple tasks simultaneously, demonstrated ability to identify and resolve issues, and effectively manage timelines
- Participate in inter-departmental workgroups to create or enhance processes
- Strong attention to quality/detail
- Good organizational and time management skills
- Willingness to work in a flexible environment
Preferred Qualifications
- Experience inside a Sponsor or CRO company
- Experience with global studies, using an outsourced CRO model
- Experience in clinical drug development with knowledge of First in Human trials
- Experience with regulatory affairs, including IND/CTA submissions
Competencies
- Collaborative – Openness, One Team
- Undaunted – Fearless, Can-do attitude
- Results Orientation – Delivering progress toward our mission. Sense of urgency in solving problems.
- Entrepreneurial Spirit – Proactive. Ownership mindset.
CRISPR Therapeutics believes in fostering a dynamic workplace that balances remote work flexibility with the benefits of in-person interactions. Our employees work at least three days on-site, creating a collaborative work environment, where we cultivate mentorship opportunities, increase cross-functional communication and offer opportunities for our employees to connect. Certain lab based and manufacturing positions are located fully on-site.
Base pay range of $85,000 to $95,000+ bonus, equity and benefits
The range provided is CRISPR Therapeutics’ reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy
Job Description:
Company Overview
Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world’s first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary
Working closely with the Clinical Trial Manager, the Clinical Trial Associate (CTA) position will assist with daily clinical trial execution activities including the coordination of documents associated with the conduct of investigational clinical studies in accordance with applicable regulations, Good Clinical Practice (GCP), and CRISPR Therapeutics standard operating procedures (SOPs). The ideal candidate will have keen attention to detail and has the ability both to prioritize and independently handle multiple tasks effectively.
This incredible opportunity will put the right candidate at the forefront of medicine, working on ground breaking trials with tremendous potential to impact patient's lives. You will join a team of incredibly dedicated professionals whose talent is matched by their commitment and passion for the work we are doing. A team that remains focused on what's important for the patient and also has an incredible track record of growth and development among them. If you are looking to learn, work hard, and make a difference, we would like to speak with you.
Responsibilities
- Help maintain tracking systems and tools to support the conduct of a clinical study from start-up to close-out
- Collect trial information and disseminate it to the internal project team, the CRO, and other stakeholders
- Coordinate study meetings, materials and agendas; recording and disseminating decisions and actions
- Responsible for internal meeting agendas/minutes as applicable
- Responsible for updating, maintaining and quality control of the eTMF, SharePoint site and shared drive
- Responsible for study laboratory sample tracking and vendor management support
- Coordinate version control of clinical documents, prioritize multiple tasks and/or projects
- Assist in coordination and tracking of clinical supply shipments, including review and approval of Regulatory Greenlight Documentation Packages
- Support Clinical Operations team in new process development or optimization
- Effectively communicate with study team members and work closely to address challenges
Minimum Qualifications
- BS/BA degree or equivalent and at least 1-3+ years experience in clinical research
- Knowledge of drug development, clinical operation processes and documentation including study start up procedures, maintenance phase, and study close out procedures
- Knowledge and implementation of the processes involved in clinical studies following Good Clinical Practice (GCP) and the Code of Federal Regulations
- Experience with eTMF; ability to directly apply essential document knowledge to file documents
- Effective communication, organizational and interpersonal/team skills
- Proficient in MS Excel, Word and PowerPoint.
- Established ability to prioritize and manage multiple tasks simultaneously, demonstrated ability to identify and resolve issues, and effectively manage timelines
- Participate in inter-departmental workgroups to create or enhance processes
- Strong attention to quality/detail
- Good organizational and time management skills
- Willingness to work in a flexible environment
Preferred Qualifications
- Experience inside a Sponsor or CRO company
- Experience with global studies, using an outsourced CRO model
- Experience in clinical drug development with knowledge of First in Human trials
- Experience with regulatory affairs, including IND/CTA submissions
Competencies
- Collaborative – Openness, One Team
- Undaunted – Fearless, Can-do attitude
- Results Orientation – Delivering progress toward our mission. Sense of urgency in solving problems.
- Entrepreneurial Spirit – Proactive. Ownership mindset.
CRISPR Therapeutics believes in fostering a dynamic workplace that balances remote work flexibility with the benefits of in-person interactions. Our employees work at least three days on-site, creating a collaborative work environment, where we cultivate mentorship opportunities, increase cross-functional communication and offer opportunities for our employees to connect. Certain lab based and manufacturing positions are located fully on-site.
Base pay range of $85,000 to $95,000+ bonus, equity and benefits
The range provided is CRISPR Therapeutics’ reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy
See All 20 Clinical Trial Manager Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Clinical Trial Manager JobsClinical Trial Manager Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Clinical Trial Manager Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Science & Research
- Biotechnology & Pharmaceuticals
What Massachusetts Employers Look For
The qualifications that appear most often in clinical trial manager jobs across Massachusetts.
- Bachelor's degree in life sciences, nursing, or a related clinical field required
- Minimum two to five years of clinical research or CRA experience preferred
- Demonstrated knowledge of ICH-GCP guidelines and FDA regulatory requirements
- Experience managing site relationships, budgets, and trial timelines simultaneously
- Proficiency with clinical trial management systems such as Medidata or Veeva Vault
- Strong written communication skills for protocol documentation and regulatory submissions
Clinical Trial Manager Jobs in Massachusetts: Frequently Asked Questions
How do you become a clinical trial manager in Massachusetts?
Most clinical trial managers in Massachusetts start with a bachelor's degree in a life science, nursing, or health-related field and build experience as a clinical research associate or study coordinator before moving into management. While Massachusetts does not require a state-issued license specific to clinical trial management, many employers prioritize the Certified Clinical Research Professional credential from the Society of Clinical Research Associates. Candidates who gain experience at Massachusetts academic medical centers or contract research organizations typically have the strongest hiring prospects.
Which companies hire clinical trial managers in Massachusetts?
Employers hiring clinical trial managers in Massachusetts right now include Moderna, Biogen, and Galderma, based on current listings on Migrate Mate as of August 2026. Massachusetts's dense concentration of pharmaceutical headquarters and academic research hospitals means hiring activity is consistent year-round, with particularly strong demand in the Greater Boston and Cambridge biotech corridor.
Which Massachusetts cities have the most clinical trial manager jobs?
The cities with the most clinical trial manager openings in Massachusetts are Boston, Cambridge, and Waltham. Boston and Cambridge lead because of their concentration of major pharmaceutical companies, contract research organizations, and world-class academic medical centers, while Worcester draws consistent demand from UMass Memorial Health and its affiliated research programs.
Are there remote clinical trial manager jobs in Massachusetts?
Yes, and more than many clinical roles, since a meaningful portion of clinical trial management involves protocol oversight, vendor communication, and data review that can be done off-site. About 90% of clinical trial manager openings tied to Massachusetts are remote or hybrid as of August 2026, reflecting how common flexible arrangements have become in this field. Site-facing responsibilities like investigator meetings and on-site monitoring visits typically still require in-person presence.
How can I get hired as a clinical trial manager in Massachusetts with little or no experience?
The most realistic entry path is a clinical research coordinator or clinical research associate role at a Massachusetts academic medical center or contract research organization, where structured mentorship and exposure to multiple therapeutic areas build the skills hiring managers look for. Large Massachusetts institutions such as Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Boston Children's Hospital regularly post study coordinator openings that serve as direct pipelines into management. Pursuing the Clinical Research Coordinator certification early signals commitment and gives candidates an edge over others with similar experience levels.
Where can I find and apply to clinical trial manager jobs in Massachusetts?
You can find and apply to clinical trial manager jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings across pharmaceutical companies, contract research organizations, and academic medical centers. Search the listings, find roles that fit your experience and preferred location, and apply directly.
See All 20 Clinical Trial Manager Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Clinical Trial Manager Jobs