Cloud Software Engineer Jobs in Massachusetts
Cloud software engineer jobs in Massachusetts are among the most active in the country, concentrated in life sciences technology, financial services, and defense and aerospace sectors, with openings at every level from entry-level associate engineer through principal and staff engineer. The heaviest hiring is in Greater Boston, Cambridge, and the Route 128 corridor, where companies like Amazon Web Services, Raytheon Technologies, and MathWorks maintain large engineering operations. The most in-demand specialties are cloud-native application development, DevOps and infrastructure automation, and multi-cloud architecture across AWS, Azure, and Google Cloud Platform. Find a role that fits below and apply directly.
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Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.
The Opportunity
You will own and shape how Praxis designs, governs, secures, and operates AWS at scale—from account structure and identity to the platforms and applications that run on them. You will be a hands-on builder, using your depth in cloud infrastructure and software engineering to create secure, reliable systems that enable our teams to move quickly.
You will work at the intersection of software engineering, cloud infrastructure, security, and operations. You will build and improve the systems that keep our teams moving fast while maintaining high standards for reliability, security, and compliance. You will work primarily in TypeScript and Python, use modern AI tooling as part of your daily engineering workflow, and take direct accountability for production operations, including on-call.
You will be expected to see problems, take ownership, and drive them through resolution. You will move quickly through incremental, well-controlled changes, question assumptions when there is a better path, and turn operational learnings into durable improvements. Just as importantly, you will raise the bar for the people and systems around you by sharing what you know, communicating clearly, and helping the broader team build and operate better.
Primary Responsibilities
- Own and evolve AWS architecture for enterprise workloads, including multi-account foundations, landing zone / Control Tower patterns, networking, security baselines, and shared platforms.
- Establish and continuously improve AWS governance, including organizational structure, SCPs, tagging, cost controls, compliance, audit readiness, and durable operational standards.
- Design and operate identity and access across AWS, including IAM, IAM Identity Center, and Microsoft Entra ID integrations for SSO, federation, role mapping, access reviews, and least-privilege access.
- Build, harden, and operate AWS platforms and full-stack services using TypeScript and Python, including compute, containers, serverless, data stores, messaging, and cloud automation as needed.
- Drive operational excellence across AWS platforms and workloads by building effective monitoring, alerting, dashboards, SLOs/SLIs, runbooks, incident response practices, and durable fixes to recurring problems; participate in the on-call rotation and own incidents through resolution and learning.
- Automate infrastructure and delivery through Infrastructure as Code—preferably Pulumi and/or SST—and CI/CD using Bitbucket Pipelines and/or GitHub Actions, with an emphasis on safe, incremental delivery and low blast radius.
- Partner across engineering and IT to translate needs into secure, maintainable solutions, improve production readiness and operational practices, mentor other engineers, and use sound judgment to move fast without breaking things.
Qualifications
- Senior-level software engineering experience, with substantial hands-on experience building and operating production systems on AWS.
- Strong full-stack engineering capability in TypeScript and Python, including APIs, services, tooling, and cloud automation.
- Deep experience with core AWS services used in enterprise environments, including IAM, Organizations, VPC, EC2, ECS/EKS or Lambda, S3, RDS/DynamoDB, CloudWatch, KMS, Config, and GuardDuty.
- Proven ability to design and operate AWS governance at scale, including multi-account strategy, policy guardrails, access control, security standards, and operational controls.
- Strong AWS networking fundamentals, including VPNs, peering, Transit Gateway, routing, DNS, and hybrid connectivity.
- Experience with enterprise SSO; Microsoft Entra ID (Azure AD) federation into AWS is strongly preferred, including SAML/OIDC, IAM Identity Center, application and role mapping, and access lifecycle practices.
- Experience working in regulated or audit-ready environments, with strong habits around change control, evidence and traceability, least privilege, and durable controls.
- Demonstrated operational ownership: able to establish meaningful alerts and monitors, reduce noise, improve reliability, respond to incidents, and turn operational learnings into engineering improvements.
- Strong Infrastructure as Code experience; Pulumi and/or SST strongly preferred. Terraform or AWS CDK experience is transferable and welcome.
- Experience with Bitbucket Pipelines and/or GitHub Actions.
- Proficient with modern AI coding and productivity tools, with the judgment to validate outputs, test changes, manage risk, and maintain production quality.
- The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.
Compensation & Benefits
At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let's achieve the impossible together!
Company Overview
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.
Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.
Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.
Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.
See All 15 Cloud Software Engineer Jobs in Massachusetts
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Find Cloud Software Engineer JobsCloud Software Engineer Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Cloud Software Engineer Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring



What Massachusetts Employers Look For
The qualifications that appear most often in cloud software engineer jobs across Massachusetts.
- Bachelor's degree in computer science, software engineering, or a closely related technical field
- Hands-on experience with at least one major cloud platform such as AWS, Azure, or Google Cloud
- Proficiency in one or more programming languages including Python, Java, Go, or TypeScript
- Familiarity with containerization and orchestration tools such as Docker and Kubernetes
- Experience designing and deploying CI/CD pipelines and infrastructure-as-code using tools like Terraform
- Strong understanding of cloud security practices, IAM policies, and compliance frameworks such as SOC 2
Cloud Software Engineer Jobs in Massachusetts: Frequently Asked Questions
How do you become a cloud software engineer in Massachusetts?
There is no state-issued license required to work as a cloud software engineer in Massachusetts. Most employers in the state expect a bachelor's degree in computer science, software engineering, or a related field, along with demonstrated cloud platform skills. Earning vendor certifications from AWS, Microsoft Azure, or Google Cloud strengthens your candidacy significantly, and many Massachusetts employers in life sciences and defense also value prior experience with regulated or high-compliance cloud environments.
How much do cloud software engineers make in Massachusetts?
Cloud software engineers in Massachusetts earn a median of about $165,210 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $102,810 for the lowest 10% to over $213,970 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire cloud software engineers in Massachusetts?
Employers hiring cloud software engineers in Massachusetts right now include Sonos, Google, and NASDAQ, based on current listings on Migrate Mate as of September 2026. Massachusetts's concentration of biotech firms along Route 128, major financial institutions in Boston, and defense contractors in the greater Lowell and Bedford areas makes it one of the most consistent hiring markets in the Northeast.
Which Massachusetts cities have the most cloud software engineer jobs?
Boston, Cambridge, and Salem have the most cloud software engineer openings in Massachusetts. Boston and Cambridge lead because of the dense concentration of technology companies, academic medical centers, and venture-backed startups, while the Route 128 corridor cities like Waltham and Burlington anchor demand from established defense contractors and enterprise software firms that have operated in the region for decades.
Are there remote cloud software engineer jobs in Massachusetts?
Yes, and more than most fields. About 83% of cloud software engineer openings tied to Massachusetts are remote or hybrid as of September 2026, reflecting the desk-based and platform-driven nature of the work. Roles focused on cloud infrastructure management, backend services, and DevOps automation tend to carry the highest remote flexibility, while positions requiring close collaboration with on-site hardware or regulated lab environments are more likely to require in-person attendance.
How can I get hired as a cloud software engineer in Massachusetts with little or no experience?
The most realistic entry path is through an associate or junior software engineer role at a Massachusetts technology company or large enterprise. Companies like MathWorks in Natick and HubSpot in Cambridge run structured new-graduate hiring programs each year. Building a portfolio of cloud projects on AWS or Azure, earning an entry-level cloud certification, and targeting companies with internship pipelines at universities like MIT, Northeastern, and UMass Amherst gives candidates without professional experience a concrete edge in the Massachusetts market.
Where can I find and apply to cloud software engineer jobs in Massachusetts?
You can find and apply to cloud software engineer jobs in Massachusetts on Migrate Mate, which lists current openings tied to the state. Search the available roles, find the ones that match your experience and preferred location, and apply directly to the employers posting them.
See All 15 Cloud Software Engineer Jobs in Massachusetts
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