Green Card Cloud Infrastructure Engineer Jobs
Cloud Infrastructure Engineer roles qualify for EB-2 and EB-3 green card sponsorship when employers run PERM labor certification through DOL. Most positions require a bachelor's degree in computer science or a related field, making EB-3 the common filing path. Sponsorship timelines vary by country of birth, so starting your job search early matters.
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Get Access To All JobsINTRODUCTION
Personalis, Inc. is a leader in advanced cancer genomics for enabling the next generation of precision cancer therapies and diagnostics. The Personalis NeXT Platform® is designed to adapt to the complex and evolving understanding of cancer, providing its biopharmaceutical customers and clinicians with information on all of the approximately 20,000 human genes, together with the immune system, from a single tissue sample. In population sequencing, Personalis operates one of the largest sequencing operations globally and is currently the sole sequencing provider to Veterans Affairs' Million Veteran Program. To enable cancer and population sequencing, Personalis' Clinical Laboratory was built with a focus on clinical accuracy, quality, big data, scale and efficiency. The laboratory is GxP-aligned as well as Clinical Laboratory Improvement Amendments of 1988-certified and College of American Pathologists-accredited. Personalis is based in Fremont, California.
SUMMARY
We are seeking a highly skilled Senior Cloud Infrastructure Engineer to architect, implement, and support cloud-first infrastructure platforms across AWS, Azure, and hybrid environments. This role will be responsible for designing scalable, secure, and highly available cloud infrastructure, managing containerized platforms, automating infrastructure deployments, and supporting critical enterprise and laboratory systems.
The ideal candidate has deep expertise in cloud technologies, Kubernetes, Docker, Infrastructure as Code (IaC), DevOps practices, and cloud security. This individual will work closely with software engineering, bioinformatics, security, laboratory operations, and compliance teams to ensure reliable and compliant infrastructure services supporting business-critical applications.
ONSITE: Monday, Tuesday, and Thursday
Responsibilities:
- Design, deploy, and manage enterprise cloud infrastructure primarily within AWS and/or Azure environments.
- Architect highly available, scalable, secure, and cost-effective cloud solutions.
- Implement cloud networking, identity management, storage, compute, monitoring, and security services.
- Support integration between cloud and on-premises infrastructure environments.
- Manage hybrid networking, VPNs, Direct Connect, ExpressRoute, and secure connectivity solutions.
- Support virtualization platforms and legacy infrastructure during cloud transformation initiatives.
- Design, deploy, and manage Kubernetes clusters in cloud and hybrid environments.
- Administer container orchestration platforms including Amazon EKS, Azure AKS, or self-managed Kubernetes environments.
- Build and maintain containerized application platforms using Docker.
- Automate infrastructure provisioning, configuration management, and deployment processes.
- Support and optimize CI/CD pipelines using GitHub Actions, GitLab CI, Azure DevOps, Jenkins, or similar platforms.
- Implement automated monitoring, alerting, scaling, backup, and recovery solutions.
- Partner with Security and Compliance teams to support HIPAA/CLIA/CAP/FDA requirements, where applicable.
- Ensure secure management of Protected Health Information (PHI) and sensitive business data.
- Partner with software engineering teams to optimize cloud-native application architectures.
REQUIRED QUALIFICATIONS:
- Bachelor's degree in Computer Science, Information Technology, Engineering, or related field.
- 7+ years of infrastructure engineering experience.
- 5+ years of hands-on cloud engineering experience in AWS, Azure, or GCP.
- 3+ years of Kubernetes administration and container platform management experience.
- Strong experience with Docker and containerized application deployment.
- Experience implementing Infrastructure as Code using Terraform or equivalent tools.
- Experience with Linux systems administration and cloud networking.
- Strong scripting and automation skills using Python, PowerShell, Bash, or similar languages.
- Experience supporting production-critical environments with high availability requirements.
TECHNICAL SKILLS:
- AWS (EC2, EKS, RDS, S3, IAM, VPC, Route53, CloudWatch, Lambda)
- Azure (AKS, Virtual Networks, Azure AD, Storage, Monitor, Key Vault)
- Multi-cloud and hybrid-cloud architectures
- Kubernetes, Docker, Helm, EKS, Terraform, Ansible and other adjacent cloud services
- Monitoring services like Splunk, Datadog or other cloud-native monitoring tools
KEY COMPETENCIES:
- Cloud Architecture & Engineering
- Kubernetes Administration
- Docker & Container Platforms
- Infrastructure Automation
- DevOps & CI/CD
- Cloud Security & Compliance
- Site Reliability Engineering (SRE)
- Disaster Recovery & Business Continuity
- Technical Leadership
- Problem Solving & Incident Management
SUCCESS METRICS:
- Cloud platform availability and reliability.
- Kubernetes cluster health and operational efficiency.
- Infrastructure automation coverage and deployment success rates.
- Compliance with HIPAA, CLIA, CAP, and security requirements.
- Cloud cost optimization and resource utilization.
- Incident response and recovery performance.
- Successful delivery of cloud modernization initiatives.
- Security and audit readiness.
The hiring range for this position is $150,000 to $180,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.
Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.
Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.
Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)
INTRODUCTION
Personalis, Inc. is a leader in advanced cancer genomics for enabling the next generation of precision cancer therapies and diagnostics. The Personalis NeXT Platform® is designed to adapt to the complex and evolving understanding of cancer, providing its biopharmaceutical customers and clinicians with information on all of the approximately 20,000 human genes, together with the immune system, from a single tissue sample. In population sequencing, Personalis operates one of the largest sequencing operations globally and is currently the sole sequencing provider to Veterans Affairs' Million Veteran Program. To enable cancer and population sequencing, Personalis' Clinical Laboratory was built with a focus on clinical accuracy, quality, big data, scale and efficiency. The laboratory is GxP-aligned as well as Clinical Laboratory Improvement Amendments of 1988-certified and College of American Pathologists-accredited. Personalis is based in Fremont, California.
SUMMARY
We are seeking a highly skilled Senior Cloud Infrastructure Engineer to architect, implement, and support cloud-first infrastructure platforms across AWS, Azure, and hybrid environments. This role will be responsible for designing scalable, secure, and highly available cloud infrastructure, managing containerized platforms, automating infrastructure deployments, and supporting critical enterprise and laboratory systems.
The ideal candidate has deep expertise in cloud technologies, Kubernetes, Docker, Infrastructure as Code (IaC), DevOps practices, and cloud security. This individual will work closely with software engineering, bioinformatics, security, laboratory operations, and compliance teams to ensure reliable and compliant infrastructure services supporting business-critical applications.
ONSITE: Monday, Tuesday, and Thursday
Responsibilities:
- Design, deploy, and manage enterprise cloud infrastructure primarily within AWS and/or Azure environments.
- Architect highly available, scalable, secure, and cost-effective cloud solutions.
- Implement cloud networking, identity management, storage, compute, monitoring, and security services.
- Support integration between cloud and on-premises infrastructure environments.
- Manage hybrid networking, VPNs, Direct Connect, ExpressRoute, and secure connectivity solutions.
- Support virtualization platforms and legacy infrastructure during cloud transformation initiatives.
- Design, deploy, and manage Kubernetes clusters in cloud and hybrid environments.
- Administer container orchestration platforms including Amazon EKS, Azure AKS, or self-managed Kubernetes environments.
- Build and maintain containerized application platforms using Docker.
- Automate infrastructure provisioning, configuration management, and deployment processes.
- Support and optimize CI/CD pipelines using GitHub Actions, GitLab CI, Azure DevOps, Jenkins, or similar platforms.
- Implement automated monitoring, alerting, scaling, backup, and recovery solutions.
- Partner with Security and Compliance teams to support HIPAA/CLIA/CAP/FDA requirements, where applicable.
- Ensure secure management of Protected Health Information (PHI) and sensitive business data.
- Partner with software engineering teams to optimize cloud-native application architectures.
REQUIRED QUALIFICATIONS:
- Bachelor's degree in Computer Science, Information Technology, Engineering, or related field.
- 7+ years of infrastructure engineering experience.
- 5+ years of hands-on cloud engineering experience in AWS, Azure, or GCP.
- 3+ years of Kubernetes administration and container platform management experience.
- Strong experience with Docker and containerized application deployment.
- Experience implementing Infrastructure as Code using Terraform or equivalent tools.
- Experience with Linux systems administration and cloud networking.
- Strong scripting and automation skills using Python, PowerShell, Bash, or similar languages.
- Experience supporting production-critical environments with high availability requirements.
TECHNICAL SKILLS:
- AWS (EC2, EKS, RDS, S3, IAM, VPC, Route53, CloudWatch, Lambda)
- Azure (AKS, Virtual Networks, Azure AD, Storage, Monitor, Key Vault)
- Multi-cloud and hybrid-cloud architectures
- Kubernetes, Docker, Helm, EKS, Terraform, Ansible and other adjacent cloud services
- Monitoring services like Splunk, Datadog or other cloud-native monitoring tools
KEY COMPETENCIES:
- Cloud Architecture & Engineering
- Kubernetes Administration
- Docker & Container Platforms
- Infrastructure Automation
- DevOps & CI/CD
- Cloud Security & Compliance
- Site Reliability Engineering (SRE)
- Disaster Recovery & Business Continuity
- Technical Leadership
- Problem Solving & Incident Management
SUCCESS METRICS:
- Cloud platform availability and reliability.
- Kubernetes cluster health and operational efficiency.
- Infrastructure automation coverage and deployment success rates.
- Compliance with HIPAA, CLIA, CAP, and security requirements.
- Cloud cost optimization and resource utilization.
- Incident response and recovery performance.
- Successful delivery of cloud modernization initiatives.
- Security and audit readiness.
The hiring range for this position is $150,000 to $180,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.
Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.
Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.
Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)
See all 483+ Green Card Cloud Infrastructure Engineer Jobs
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Get Access To All JobsTips for Finding Green Card Sponsorship as a Cloud Infrastructure Engineer
Document your cloud certifications before applying
AWS, Azure, and GCP certifications strengthen your PERM file by demonstrating that your qualifications align with the posted job requirements. Gather official certificates and transcripts now so your employer's attorney can build a clean I-140 petition.
Target employers with active PERM filing history
Search OFLC disclosure data to identify companies that have filed PERM applications for cloud infrastructure roles in the past two years. Repeat filers have established internal processes, which shortens the time from offer to petition.
Use Migrate Mate to filter green card sponsoring roles
Search Migrate Mate specifically for Cloud Infrastructure Engineer positions tagged with EB-2 or EB-3 sponsorship. This filters out employers who only sponsor H-1B visas, saving you weeks of follow-up during offer-stage conversations.
Understand how your birth country affects your priority date
If you were born in India or China, EB-3 backlogs can extend wait times significantly. Confirm the current priority date in the USCIS Visa Bulletin before accepting an offer, so your timeline expectations are grounded in your actual situation.
Negotiate who covers PERM advertising costs
PERM requires the employer to run a mandatory recruitment campaign before DOL will certify the role. Employers must legally bear these costs, but you can ask upfront whether the company has run PERM before and has a law firm already engaged.
Confirm the job description matches your specialty occupation
PERM filings are tied to a specific job description. If the posted role lists duties across networking, DevOps, and security without a defined specialty, DOL audits become more likely. Ask hiring managers to verify the description before PERM is filed.
Green Card Cloud Infrastructure Engineer: Frequently Asked Questions
Does a Cloud Infrastructure Engineer role qualify for EB-2 or EB-3 sponsorship?
Most Cloud Infrastructure Engineer positions qualify for EB-3 because they require a bachelor's degree in computer science, information technology, or a related field. EB-2 applies when the role requires an advanced degree or when your credentials are strong enough for a National Interest Waiver self-petition. Your employer's attorney will assess which category fits the specific job description and your qualifications.
How does green card sponsorship differ from H-1B for this role?
H-1B is a temporary work status, while green card sponsorship via PERM leads to permanent residency. EB-3 has no annual lottery and no cap that resets each year the way the H-1B general cap does, though country-of-birth backlogs apply separately. PERM also requires your employer to run a formal recruitment process and file with DOL before submitting the I-140 petition to USCIS, making the overall timeline longer but the outcome permanent.
What does the PERM labor certification process look like for a cloud infrastructure role?
Your employer files an Application for Permanent Employment Certification with DOL after completing a mandatory recruitment campaign to show no qualified U.S. workers are available for the role. For Cloud Infrastructure Engineer positions, the job description must specify a defined minimum requirement, typically a bachelor's degree in a technical field. Once DOL certifies the application, your employer files the I-140 immigrant petition with USCIS, which sets your priority date.
How do I find employers who will sponsor a green card for cloud infrastructure roles?
Search Migrate Mate for Cloud Infrastructure Engineer positions with active EB-2 or EB-3 sponsorship. You can also review OFLC PERM disclosure data to identify companies that have successfully filed for similar roles. Prioritizing employers with existing PERM filing history reduces the risk of starting a process the company isn't equipped to complete.
Can my employer use E-Verify enrollment to speed up my green card process?
E-Verify enrollment does not directly accelerate PERM certification or I-140 adjudication, but it signals that the employer maintains compliant hiring practices, which can matter during DOL audit reviews. E-Verify participation is required for federal contractors and STEM OPT sponsoring employers but is not mandatory for all PERM filers. Asking whether a prospective employer is enrolled in E-Verify is a reasonable due-diligence step during your offer evaluation.