H-1B Visa Clinical Laboratory Scientist Jobs
Clinical Laboratory Scientist roles qualify as H-1B specialty occupations because they require at least a bachelor's degree in clinical laboratory science or a related field. Many hospital systems, reference labs, and diagnostic companies sponsor H-1B visas for CLS professionals, particularly in high-demand specialties like microbiology, hematology, and molecular diagnostics.
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Get Access To All JobsINTRODUCTION
Ready to redefine what's possible in molecular diagnostics? Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
ROLE AND RESPONSIBILITIES
We are looking for driven contract Clinical Laboratory Scientists (with California Clinical Laboratory Scientist License) to join our team on a part-time basis (up to 20 hours per week). In this role, you will perform UNITY, the only non-invasive prenatal test (NIPT) that can detect inherited disorders such as sickle cell disease, spinal muscular atrophy, and cystic fibrosis in the baby directly from maternal blood. These disorders are extremely severe, but early detection and intervention can significantly improve outcomes. You will join our growing superstar CLIA team responsible for end-to-end processing of pregnancy blood samples in a high complexity, high-growth CLIA setting. The Clinical Laboratory Scientist is an onsite contractor position.
Shift Hours: Flexible (Preferably Saturday AM/PM, Sunday AM, Monday PM)
Responsibilities:
- Performs clinical laboratory assays to provide data for diagnosis, treatment, and prevention of disease.
- Performs quality control studies to ensure the accuracy of clinical data.
- Verifies instrument performance by checking and calibrating specific lab instruments and documents data.
- Contributes to troubleshooting, training, and continuous process improvement.
BASIC QUALIFICATIONS
- Bachelor's degree in the chemical, physical or biological sciences
- 0-2 years of CLS experience in a clinical setting
- A current California Clinical Laboratory Scientist License that meets requirements for Testing Personnel under CLIA regulations (42 CFR, part 493) (California, CGMBS or Generalist license is required).
- Advanced knowledge of Google Docs, Word, Excel, basic statistics and familiarity with LIMS systems
- Strong attention to detail and ability to work flexibly and well under given timeframes.
- Self-starter and dynamic team player with excellent verbal and written skills.
PREFERRED QUALIFICATIONS
Nice-To-Haves:
- Start-up experience
- Knowledge of medical genetics
- Experience in a cell-free DNA setting and manual molecular biology protocols
BENEFITS AND PERKS
- Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
- The ability to indirectly or directly change the lives of hundreds of thousands patients
- Daily on-site lunches provided from top eateries
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
For this position, the target hourly rate is: $70 per hour.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
INTRODUCTION
Ready to redefine what's possible in molecular diagnostics? Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
ROLE AND RESPONSIBILITIES
We are looking for driven contract Clinical Laboratory Scientists (with California Clinical Laboratory Scientist License) to join our team on a part-time basis (up to 20 hours per week). In this role, you will perform UNITY, the only non-invasive prenatal test (NIPT) that can detect inherited disorders such as sickle cell disease, spinal muscular atrophy, and cystic fibrosis in the baby directly from maternal blood. These disorders are extremely severe, but early detection and intervention can significantly improve outcomes. You will join our growing superstar CLIA team responsible for end-to-end processing of pregnancy blood samples in a high complexity, high-growth CLIA setting. The Clinical Laboratory Scientist is an onsite contractor position.
Shift Hours: Flexible (Preferably Saturday AM/PM, Sunday AM, Monday PM)
Responsibilities:
- Performs clinical laboratory assays to provide data for diagnosis, treatment, and prevention of disease.
- Performs quality control studies to ensure the accuracy of clinical data.
- Verifies instrument performance by checking and calibrating specific lab instruments and documents data.
- Contributes to troubleshooting, training, and continuous process improvement.
BASIC QUALIFICATIONS
- Bachelor's degree in the chemical, physical or biological sciences
- 0-2 years of CLS experience in a clinical setting
- A current California Clinical Laboratory Scientist License that meets requirements for Testing Personnel under CLIA regulations (42 CFR, part 493) (California, CGMBS or Generalist license is required).
- Advanced knowledge of Google Docs, Word, Excel, basic statistics and familiarity with LIMS systems
- Strong attention to detail and ability to work flexibly and well under given timeframes.
- Self-starter and dynamic team player with excellent verbal and written skills.
PREFERRED QUALIFICATIONS
Nice-To-Haves:
- Start-up experience
- Knowledge of medical genetics
- Experience in a cell-free DNA setting and manual molecular biology protocols
BENEFITS AND PERKS
- Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
- The ability to indirectly or directly change the lives of hundreds of thousands patients
- Daily on-site lunches provided from top eateries
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
For this position, the target hourly rate is: $70 per hour.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
See all 1,238+ Clinical Laboratory Scientist jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Clinical Laboratory Scientist roles.
Get Access To All JobsTips for Finding H-1B Visa Sponsorship as a Clinical Laboratory Scientist
Verify your ASCP certification before applying
USCIS expects documentary proof that your role meets specialty occupation standards. Your ASCP Board of Certification credential is the strongest evidence linking your degree to the CLS job classification. Have it ready before submitting any application.
Target reference labs and hospital networks first
Large reference laboratories and multi-site hospital systems file H-1B petitions regularly and have established immigration programs. Smaller independent labs often lack the infrastructure to sponsor, so filtering by employer type saves significant time in your search.
Check prevailing wage levels using OFLC Wage Search
Your H-1B petition requires a wage at or above the DOL prevailing wage for your CLS specialty and work location. Pull the current wage level before negotiating an offer so you can confirm the employer's proposed salary clears the legal threshold.
Search H-1B filing history on Migrate Mate
Filter by occupation code to see which employers have filed H-1B petitions for Clinical Laboratory Scientist roles. This lets you prioritize outreach to labs and health systems with a documented sponsorship track record rather than guessing.
Ask about E-Verify enrollment during the offer stage
If you're on STEM OPT or a cap-gap extension, your employer must be E-Verify enrolled to maintain your work authorization. Confirm enrollment before accepting an offer, not after, since unenrolled employers can't legally employ you under those statuses.
Get your foreign credentials evaluated early in the process
If your clinical laboratory degree is from outside the U.S., USCIS will scrutinize the equivalency to a U.S. bachelor's degree. A credential evaluation from a NACES-member organization strengthens the specialty occupation argument in your employer's I-129 petition.
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Find Clinical Laboratory Scientist JobsClinical Laboratory Scientist H-1B Visa: Frequently Asked Questions
Does a Clinical Laboratory Scientist role qualify as an H-1B specialty occupation?
Yes. USCIS treats Clinical Laboratory Scientist as a specialty occupation because the position typically requires at least a bachelor's degree in clinical laboratory science, medical laboratory science, or a closely related field. The O*NET profile for this occupation confirms the degree requirement, which is the core test for specialty occupation status. Your employer documents this in the H-1B petition.
Which types of employers sponsor H-1B visas for Clinical Laboratory Scientists?
Hospital systems, large reference laboratories, public health departments, and academic medical centers are the most consistent H-1B sponsors for CLS roles. These organizations file petitions regularly and have immigration counsel on retainer. Smaller community labs and physician office labs sponsor far less often because the administrative overhead of H-1B sponsorship doesn't fit their operational model. Use Migrate Mate to identify employers with verified H-1B filing history in this occupation.
Does my ASCP certification affect my H-1B eligibility?
It strengthens your petition significantly. USCIS evaluates whether the specific job requires a degree in a directly related field. The ASCP Board of Certification credential documents that you meet the professional standards tied to that degree requirement, which reduces the likelihood of a Request for Evidence challenging specialty occupation status. Some employers list ASCP certification as a condition of employment, which further supports the argument.
Can a Clinical Laboratory Scientist change employers while on H-1B status?
Yes, through H-1B portability under AC21. Once your current petition has been approved and you've been in valid H-1B status, a new employer can file a transfer petition and you can start working as soon as that petition is received by USCIS. The new employer must file before your current status expires, and the new role must still qualify as a specialty occupation in the same or a related field.
How does the H-1B cap lottery affect Clinical Laboratory Scientists at cap-exempt employers?
If your employer is a nonprofit research institution, university, or government research organization, the H-1B cap and lottery don't apply. You can file at any time of year and start work once the petition is approved. Most hospital systems and commercial reference labs are cap-subject, meaning your petition enters the annual lottery held each March. Understanding this distinction matters when comparing job offers.
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