H-1B Visa People Operations Manager Jobs
People Operations Manager roles qualify for H-1B sponsorship as specialty occupations requiring a bachelor's degree in human resources, business administration, or a related field. Many mid-size and enterprise employers sponsor H-1B holders for these roles, particularly where HR systems expertise, workforce analytics, or multi-state compliance knowledge is central to the position.
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Get Access To All JobsINTRODUCTION
Ready to redefine what's possible in molecular diagnostics? Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
ABOUT THE ROLE
BillionToOne is looking for a People Operations Manager to join our growing People team and play a critical role in scaling our people programs, systems, and operations. This role will own and enhance core People Ops programs while serving as a key partner in driving operational excellence, vendor strategy, and data-informed decision-making.
The ideal candidate brings deep expertise in benefits, strong program and project management skills, and a data-driven mindset, with the ability to anticipate needs and proactively improve processes in a fast-paced, high-growth environment.
This is a hybrid role (2–3 days onsite per week at our Menlo Park and/or Union City office) reporting to the Associate Director of People Operations.
Responsibilities:
- Design, optimize, and scale core People Ops programs (onboarding, offboarding, performance cycles, engagement/recognition, and compliance), driving strategy, scalability, and continuous improvement
- Own and scale benefits strategy and operations, serving as the primary lead for vendor partnerships (benefits brokers, payroll providers, etc.)
- Act as the program manager for performance cycles, driving end-to-end execution, stakeholder alignment, and continuous improvement
- Design and implement scalable processes and systems, proactively identifying gaps and driving operational efficiency
- Partner with the Associate Director to operationalize strategic initiatives (e.g., recognition program, engagement survey, etc.)
- Maintain strong policy and compliance knowledge, recommending updates to enhance both compliance and employee experience
- Serve as the Tier 2 escalation point for complex employee inquiries, resolving issues independently and escalating only critical matters as needed
QUALIFICATIONS
- 5+ years of experience in People Operations, HR Generalist, or similar roles, preferably in a high-growth or startup environment
- Strong expertise in benefits administration and vendor management
- Proven experience leading cross-functional programs or cycles (e.g., performance management, compensation, or engagement programs)
- Demonstrated ability to design and improve scalable processes and systems
- Strong analytical skills with experience using data to drive decisions
- Excellent project management, organizational, and prioritization skills
- Strong communication skills with the ability to influence and partner across levels
- High attention to detail, sound judgment, and a proactive mindset
- “Scrappy,” solutions-oriented approach with a focus on continuous improvement
- Previous experience in start-up is highly desired
BENEFITS AND PERKS:
- Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousands patients
- Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
- Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
- Supplemental fertility benefits coverage
- Retirement savings program including a 4% Company match
- Increase paid time off with increased tenure
- Latest and greatest hardware (laptop, lab equipment, facilities)
- Daily on-site lunches provided from top eateries
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).
For this position, we offer a total compensation package of $259,893 per year, including a base pay range of $139,340 - $160,777 per year.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
INTRODUCTION
Ready to redefine what's possible in molecular diagnostics? Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
ABOUT THE ROLE
BillionToOne is looking for a People Operations Manager to join our growing People team and play a critical role in scaling our people programs, systems, and operations. This role will own and enhance core People Ops programs while serving as a key partner in driving operational excellence, vendor strategy, and data-informed decision-making.
The ideal candidate brings deep expertise in benefits, strong program and project management skills, and a data-driven mindset, with the ability to anticipate needs and proactively improve processes in a fast-paced, high-growth environment.
This is a hybrid role (2–3 days onsite per week at our Menlo Park and/or Union City office) reporting to the Associate Director of People Operations.
Responsibilities:
- Design, optimize, and scale core People Ops programs (onboarding, offboarding, performance cycles, engagement/recognition, and compliance), driving strategy, scalability, and continuous improvement
- Own and scale benefits strategy and operations, serving as the primary lead for vendor partnerships (benefits brokers, payroll providers, etc.)
- Act as the program manager for performance cycles, driving end-to-end execution, stakeholder alignment, and continuous improvement
- Design and implement scalable processes and systems, proactively identifying gaps and driving operational efficiency
- Partner with the Associate Director to operationalize strategic initiatives (e.g., recognition program, engagement survey, etc.)
- Maintain strong policy and compliance knowledge, recommending updates to enhance both compliance and employee experience
- Serve as the Tier 2 escalation point for complex employee inquiries, resolving issues independently and escalating only critical matters as needed
QUALIFICATIONS
- 5+ years of experience in People Operations, HR Generalist, or similar roles, preferably in a high-growth or startup environment
- Strong expertise in benefits administration and vendor management
- Proven experience leading cross-functional programs or cycles (e.g., performance management, compensation, or engagement programs)
- Demonstrated ability to design and improve scalable processes and systems
- Strong analytical skills with experience using data to drive decisions
- Excellent project management, organizational, and prioritization skills
- Strong communication skills with the ability to influence and partner across levels
- High attention to detail, sound judgment, and a proactive mindset
- “Scrappy,” solutions-oriented approach with a focus on continuous improvement
- Previous experience in start-up is highly desired
BENEFITS AND PERKS:
- Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousands patients
- Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
- Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
- Supplemental fertility benefits coverage
- Retirement savings program including a 4% Company match
- Increase paid time off with increased tenure
- Latest and greatest hardware (laptop, lab equipment, facilities)
- Daily on-site lunches provided from top eateries
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).
For this position, we offer a total compensation package of $259,893 per year, including a base pay range of $139,340 - $160,777 per year.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
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Get Access To All JobsTips for Finding H-1B Visa Sponsorship as a People Operations Manager
Verify your role meets specialty occupation
USCIS scrutinizes People Operations roles more than technical positions. Pull the O*NET profile for HR Managers to document that your specific duties require a directly related bachelor's degree, not just any degree.
Target employers with active LCA filings
Use Migrate Mate to filter People Operations Manager openings by employers who have certified Labor Condition Applications for HR titles. This confirms the employer has already navigated DOL prevailing wage requirements for the role.
Confirm prevailing wage before the offer stage
Run your target job title and location through the OFLC Wage Search before you negotiate. DOL sets four wage levels for HR Managers, and your offer must meet at least Level I or your employer's LCA will be rejected.
Ask whether the employer uses a staffing or PEO model
H-1B sponsorship for People Operations roles gets complicated when a professional employer organization is the legal employer of record. USCIS requires the petitioning entity to control your day-to-day work, so clarify this before accepting an offer.
Document systems expertise in your petition materials
USCIS RFEs on People Operations petitions often challenge whether the role genuinely requires a specialized degree. Your resume and support letter should tie your HRIS, benefits administration, or workforce planning work directly to your degree field.
File premium processing if your start date is firm
USCIS standard processing for I-129 petitions can run several months. If your employer sets a definite start date, premium processing upgrades USCIS adjudication to 15 business days and protects you against delays that would void your offer.
People Operations Manager jobs are hiring across the US. Find yours.
Find People Operations Manager JobsPeople Operations Manager H-1B Visa: Frequently Asked Questions
Does a People Operations Manager role qualify as a specialty occupation for H-1B purposes?
Yes, but the petition needs to be built carefully. USCIS requires that the role normally requires a bachelor's degree in a specific field such as human resources, organizational psychology, or business administration. Generic management duties can trigger an RFE, so the job description and support letter must tie each core responsibility directly to a specialized body of knowledge.
Which types of employers sponsor H-1B visas for People Operations Manager positions?
Technology companies, healthcare systems, financial services firms, and large professional services organizations are the most consistent H-1B sponsors for People Operations roles. These employers typically have in-house immigration counsel and established HR compliance infrastructure. You can browse verified H-1B sponsoring employers hiring for this title on Migrate Mate, filtered by LCA filing history.
How does the H-1B prevailing wage requirement affect People Operations Manager offers?
DOL requires your employer to pay at least the prevailing wage for HR Managers in your specific metro area, as determined by the OFLC Wage Search. The wage level assigned to your role, from Level I for entry-level to Level IV for senior positions, directly shapes your minimum offer. Employers who underpay relative to your actual seniority risk DOL audits and LCA decertification.
Can a People Operations Manager transfer their H-1B to a new employer mid-status?
Yes. Under H-1B portability rules, you can start working for a new employer as soon as the new I-129 petition is filed with USCIS, as long as your previous H-1B was approved and you've maintained lawful status. The new employer must file a new LCA with DOL and a new I-129 petition before or on your start date. You don't need to wait for approval to begin work.
What makes a People Operations Manager petition more likely to receive an RFE?
USCIS issues RFEs on these petitions most often when the job description includes duties that don't require a specific degree, such as general administrative oversight or employee relations tasks that a non-specialist could perform. Employers can reduce RFE risk by drafting job descriptions that emphasize HR technology implementation, compliance program management, or workforce analytics, and by tying each duty to a relevant academic discipline.
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