H-1B Visa Vendor Manager Jobs
Vendor Manager roles qualify for H-1B sponsorship as specialty occupations requiring a bachelor's degree in supply chain, business, or a related field. Employers in tech, retail, and manufacturing regularly file LCAs for this title. The 85,000-slot annual cap and lottery make employer selection critical.
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INTRODUCTION
Who Are We?
Our company is based on the science of our founder, Stanley Qi, one of the original CRISPR co-inventors who then furthered the technology so that DNA does not need to be cut to accomplish gene regulation. Instead, we regulate the epigenome to suppress and activate multiple genes simultaneously. We are further evolving the platform and leveraging its strengths to address unmet medical needs.
We are looking for exceptional team members who want an active role in building a rapidly growing biotech.
Position Summary
Position: Vendor Manager, Clinical Operations
LOCATION
Location: South San Francisco, CA
OPPORTUNITY:
Epicrispr Biotechnologies is seeking a Vendor Manager to join our growing Clinical Operations team. This role will play a critical part in overseeing vendor relationships, contracts, and budgets to support the successful execution of our clinical programs. This is a highly cross-functional role partnering closely with Clinical Operations, Finance, Legal, and external vendors to ensure studies are executed efficiently and in alignment with timelines, scope, and budget.
ROLES AND RESPONSIBILITIES:
- Primary administrative point of contact for vendor coordination and communications, ensuring alignment with study priorities defined by Clinical Operations.
- Handle logistical setup of new vendors including coordinating contract reviews with internal stakeholders and legal and budget negotiation, in alignment with study scope and requirements defined by Clinical Operations.
- Manage all existing clinical vendors, requiring contract oversight and coordination with legal and internal teams, budget and PO oversight alongside internal finance and accounting, while partnering with the CTM and other Clinical Operations team members to ensure vendor deliverables align with study needs.
- Oversee site master budgets and ensure alignment with protocol updates, in coordination with CTM and Clin Ops priorities.
- Approve vendor invoices and budgets, including pass throughs from CRO, ensuring consistency with agreed scopes of work and escalation of discrepancies as needed.
- Support CMO, CTM, and Clinical Operations Lead with review of budget reporting from CRO alongside finance and accounting team.
- Track vendor performance, deliverables, contractual obligations, and escalate risks or delays to the Clinical Operations Lead.
REQUIREMENTS
- Bachelor’s degree in life sciences, business, or related field required
- Typically 5+ years of experience in clinical operations, vendor management, or clinical trial management within biotech, pharma, or CRO environments
- Strong understanding of clinical trial processes, vendor oversight, and GCP/ICH guidelines
- Experience managing contracts, budgets, and vendor relationships across multiple studies or programs
- Familiarity with CRO models, pass-through costs, and financial tracking processes
- Excellent organizational and project management skills with strong attention to detail
- Strong communication and stakeholder management skills, with the ability to work cross-functionally
- Ability to manage multiple priorities in a fast-paced, evolving environment
- Proficiency with clinical systems (e.g., CTMS, eTMF) and financial tracking tools preferred
COMPENSATION
Compensation: The salary range for this position is $135,000 to $145,000 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.
Epicrispr Biotechnologies is an early-stage biotechnology company developing a novel technology platform that can provide safe and persistent control of targeted gene regulation. Our proprietary platform represents an entirely new class of therapeutics that can be leveraged to treat severe disease across numerous therapeutic areas, including complex diseases impacted by multiple genes.
Epicrispr Biotechnologies provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
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Get Access To All JobsTips for Finding H-1B Visa Sponsorship as a Vendor Manager
Match your degree to the LCA job description
USCIS scrutinizes whether your degree field directly supports the Vendor Manager role. Supply chain, business administration, or operations management degrees align cleanest. A mismatch between your transcript and the employer's LCA job duties is a common RFE trigger.
Filter employers by LCA filing history
Use Migrate Mate to identify companies that have filed Labor Condition Applications for Vendor Manager titles specifically. Employers with consistent LCA history for this role are far more likely to have an established H-1B sponsorship process already in place.
Target cap-exempt employers to skip the lottery
Universities, nonprofits affiliated with higher education, and certain research institutions are cap-exempt. Vendor Manager roles exist at procurement offices within these organizations, and a cap-exempt filing means your petition gets adjudicated without waiting for an April lottery slot.
Verify the prevailing wage tier before negotiating
Run your target job title and location through the OFLC Wage Search before accepting an offer. The LCA must certify wages at or above the DOL prevailing wage for your metro area, and knowing your wage level upfront prevents offers that can't legally support your H-1B petition.
Confirm the specialty occupation classification with O*NET
Vendor Manager maps to multiple SOC codes depending on the employer's industry. Pull the O*NET occupation profile for your specific role to confirm the listed education requirements match your credentials before the employer files, since USCIS will use the same profile to evaluate specialty occupation status.
Ask about premium processing during offer negotiation
Standard H-1B adjudication can run several months, leaving you in limbo between jobs. USCIS offers premium processing for a faster decision. Clarify during the offer stage whether the employer will cover this cost, since it's not guaranteed and isn't included in most standard sponsorship packages.
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Find Vendor Manager JobsVendor Manager H-1B Visa: Frequently Asked Questions
Does a Vendor Manager role qualify as an H-1B specialty occupation?
Yes, provided the employer's job description requires at minimum a bachelor's degree in a directly related field such as supply chain management, business administration, or operations. USCIS evaluates each petition individually, so the employer's LCA and job duties documentation needs to establish that a specific degree is an actual requirement, not merely preferred.
Which industries sponsor H-1B visas most often for Vendor Manager roles?
Technology companies, large retailers, logistics firms, and manufacturers are the most active H-1B sponsors for Vendor Manager titles based on DOL LCA disclosure data. These industries operate complex supplier networks that regularly justify dedicated vendor management headcount at the specialty occupation level. You can browse verified H-1B sponsoring employers in this category on Migrate Mate.
Can my employer file an H-1B for a Vendor Manager role if I'm currently on OPT?
Yes. Your employer files the H-1B petition in April for an October 1 start date while you remain authorized on OPT. If your OPT expires before October 1 and you're selected in the lottery, the cap-gap rule extends your OPT authorization through September 30, bridging the gap between your OPT end date and your H-1B start date.
What documentation strengthens an H-1B petition for a Vendor Manager position?
The employer needs a certified LCA that matches the actual job duties and wage level, a detailed support letter explaining why the role requires a specific degree, and evidence that vendor management at their organization is genuinely a specialty occupation. On your end, official transcripts, any professional certifications in supply chain or procurement, and employment verification letters all support the petition.
How does the H-1B lottery affect my job search strategy as a Vendor Manager candidate?
With a 85,000-slot annual cap and significantly more registrations filed each year, selection is not guaranteed. Prioritizing employers that are cap-exempt, have a history of filing multiple H-1B petitions, or are willing to use premium processing narrows your risk. Starting your search early enough to receive and accept an offer before the March registration window is essential to any realistic timeline.
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