Human Resources Assistant Jobs in Boston, MA
Human Resources Assistant jobs in Boston are concentrated in the Longwood Medical Area, Back Bay, and the Seaport District, driven by the city's large healthcare systems, universities, and financial services firms. Employers actively hiring right now include Boston University, Omni Hotels, and Boston Public Schools. Scan the live roles below and apply to whichever ones fit.
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About Avalyn:
Avalyn aims to transform the treatment paradigm for pulmonary fibrosis and other serious, rare respiratory diseases. The company is advancing optimized inhaled formulations of established antifibrotic medicines designed to deliver drug directly to the lungs, enhance local efficacy, and reduce systemic side effects. Avalyn's AP01 program is an optimized inhaled formulation of pirfenidone currently being evaluated in MIST, a global Phase 2b clinical trial in patients with progressive pulmonary fibrosis (PPF). AP01 has demonstrated encouraging safety and clinical activity across Phase 1b and an ongoing, multi-year open-label extension trial, with long-term data supporting the potential to preserve lung function while improving tolerability relative to historical oral pirfenidone. Avalyn's AP02 program is an optimized inhaled formulation of nintedanib currently being evaluated in AURA, a global Phase 2 clinical trial in patients with idiopathic pulmonary fibrosis (IPF). Avalyn is also advancing AP03, an inhaled fixed-dose combination of pirfenidone and nintedanib, designed to deliver multiple antifibrotic mechanisms through a single lung-targeted platform. By leveraging its proprietary drug-device approach and deep expertise in rare respiratory disease development, Avalyn aims to establish a new standard of care in pulmonary fibrosis through inhaled, lung-targeted therapies. For more information, please visit avalynpharma.com and follow the company on LinkedIn.
Position Overview:
As Avalyn Pharma advance from a pre-commercial company into the next phase of our growth, we are seeking an HR Manager or Sr. Manager who is eager to develop broad, cross-functional HR expertise rather than specialize narrowly in a single function.
This opportunity is ideal for an HR professional early-to-mid in their career who is naturally curious about the discipline and excited by variety. One day you may partner on full-cycle recruiting, another you may lead a compliance audit, build an intern program from the ground up, or improve the systems that support our People operations. This is intentionally a broad role designed to build expertise across the full employee lifecycle while working alongside a small, collaborative HR team committed to your development. This role will report into the VP, HR.
Key Responsibilities:
Talent Acquisition — Partner on the Hiring Journey
- Partner with hiring managers and external recruiting partners to define hiring strategies, role requirements, success profiles, and interview processes
- Contribute to sourcing strategy and help maintain strong candidate pipelines across clinical, regulatory, and G&A functions
- Manage and continuously improve Greenhouse workflows, including coordination with external recruiting partners
- Help ensure a candidate's experience consistent with Avalyn's culture and standards
- Support offer development and compensation alignment, with guidance from HR leadership as this skill set develops
Intern Program — Build and Lead a HR Initiative
- Own Avalyn's summer intern program from design through execution
- Partner with business leaders to identify meaningful project work and deliver a strong intern experience
- Use this initiative as an opportunity to build program management and leadership capability
Compliance & Audit — Build a Strong HR Foundation
- Own compliance tracking across federal, state, and multi-state employment law requirements
- Lead leave of absence administration, including FMLA and MA PFML
- Manage I-9 processing, background checks, and employment verifications
- Take the lead on internal and external audits, including payroll, benefits, and worker classification, as a means of developing deep HR expertise
- Maintain audit-ready records and partner with HR leadership on policy interpretation
HR Operations & Systems — Shape How We Work
- Play a leading role in core lifecycle processes, including onboarding, offboarding, transfers, and employee data integrity
- Support HRIS and systems administration, ensuring data accuracy across Greenhouse, ADP Workforce Now, Absorb, and related platforms
- Identify process inefficiencies and implement scalable solutions, including checklists, templates, and documentation
- Partner with payroll to ensure accurate, timely processing
Qualifications:
Required
- A minimum of a Bachelor's degree with 5–8+ years of progressive Human Resources experience, including exposure to talent acquisition, HR operations, or a combination of both
- Demonstrated curiosity and a desire to build expertise across multiple Human Resources disciplines
- Comfort operating in a fast-paced, evolving environment with shifting priorities and expanding scope
- Strong interpersonal, communication, and organizational skills, with a collaborative, team-oriented approach
- Experience with an ATS (e.g., Greenhouse) and/or HRIS platform (e.g., ADP Workforce Now) preferred but not required; training will be provided
Preferred
- Experience in biotech, life sciences, or another high-growth industry
- Exposure to compliance, leave administration, audit support, or other core HR operational functions
- A demonstrated track record of building a program, process, or workflow from the ground up
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Who's Hiring
- Boston University11

- Omni Hotels7

- Boston Public Schools7

- Sunrise Senior Living7

- BXP4

Top Industries Hiring
- Airlines
- Education
- Medical Devices
- Science & Research
- Staffing & Recruiting
Human Resources Assistant Jobs in Boston: Frequently Asked Questions
How do I get a human resources assistant job in Boston?
Target Boston's dominant hiring sectors: healthcare systems in Longwood, universities along Commonwealth Avenue, and financial services firms in Back Bay and the Financial District. Candidates who stand out here typically have experience with HR information systems, benefits administration, or recruiting coordination. Familiarity with the fast-paced, compliance-heavy environments common to Boston's hospital networks and higher-ed institutions gives applicants a clear edge over generalist candidates.
Which companies hire human resources assistants in Boston?
Companies currently hiring human resources assistants in Boston include Boston University, Omni Hotels, and Boston Public Schools, per current listings on Migrate Mate as of August 2026. Boston's mix of large academic medical centers, research universities, and established financial services employers makes it a consistently active market for HR support roles across both large enterprise teams and mid-size organizations.
Are there remote human resources assistant jobs in Boston?
Yes, though remote availability varies since many HR assistant duties involve in-person employee interactions, onboarding, and file management. About 42% of human resources assistant openings tied to Boston are remote or hybrid as of August 2026, with fully remote roles most common in recruiting coordination and HR data entry functions at Boston's larger tech and financial services employers.
How can I get a human resources assistant job in Boston with little or no experience?
The most realistic entry path in Boston is through administrative or receptionist roles at healthcare systems, universities, or staffing agencies, which regularly hire for HR support without requiring prior HR titles. Boston-area community colleges and Northeastern University's cooperative education program also place entry-level candidates directly with local employers. Proficiency in HRIS platforms like Workday or ADP and strong organizational skills consistently give new candidates an advantage in this market.
Which industries hire the most human resources assistants in Boston?
Most human resources assistant openings in Boston sit in Airlines, Education, and Medical Devices, per current listings on Migrate Mate as of August 2026. Boston's concentration of world-class hospitals, research universities, and asset management firms creates sustained, year-round demand for HR support staff across all experience levels.
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