Manufacturing Jobs in Washington
Manufacturing jobs in Washington are concentrated in the Puget Sound corridor, Spokane, and the Tri-Cities, where aerospace, food processing, and defense supply chains sustain demand from entry-level assemblers to senior process engineers. Boeing, PACCAR, and Darigold are among the employers with deep, lasting manufacturing footprints in the state. Precision machining, semiconductor fabrication support, and advanced composites are among the most sought-after specialties in current Washington postings. Find a role that fits below and apply directly.
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Join Us in Bringing Hope to Life
Our purpose is to bring hope to life by enabling life‑changing therapies for patients around the globe, creating a healthier and happier tomorrow. To advance this purpose, we rely on team members who value excellence, collaboration, and meaningful work. If this resonates with you, we invite you to explore the role further and apply.
Job Summary
We are looking for an Upstream Manufacturing Manager to lead GMP upstream manufacturing operations across mammalian and microbial production platforms. This role is responsible for overseeing daily manufacturing activities, ensuring compliance with established processes and standards, and delivering safe, reliable, and efficient execution of clinical and commercial production campaigns.
The Upstream Manufacturing Manager provides leadership and direction to manufacturing teams, ensuring operational readiness, schedule adherence, and continuous improvement while supporting technology transfer, process implementation, and commercial manufacturing activities.
About the Manufacturing Team
You'll join a Manufacturing organization responsible for the production of biologics across multiple modalities and stages of development. The team partners closely with Quality, MSAT, Engineering, Supply Chain, and other operational functions to ensure safe, compliant, and efficient manufacturing operations that support both clinical and commercial programs.
Key Responsibilities
Lead upstream manufacturing operations across mammalian and microbial processes.
Monitor and improve compliance with quality systems, safety procedures, and company policies.
Determine production priorities, staffing requirements, and shift schedules to support manufacturing objectives.
Ensure effective communication and operational alignment across shifts through the Daily Management System (DMS).
Monitor manufacturing operations to ensure compliance with SOPs, batch records, and GMP requirements.
Identify, address, and prevent operational issues that may impact safety, quality, reliability, identity, or purity (SQRIP).
Train, coach, and mentor manufacturing associates and supervisors.
Review and approve manufacturing documentation.
Manage team performance, goal setting, development planning, and performance reviews.
Coordinate resources and activities across manufacturing areas to meet production goals and timelines.
Ensure equipment, personnel, materials, and manufacturing suites are prepared for scheduled operations.
Support technology transfer, process implementation, PPQ, clinical manufacturing, and commercial manufacturing activities.
Monitor production performance, equipment availability, schedule adherence, and operational risks.
Drive continuous improvement initiatives focused on safety, quality, productivity, reliability, and cost.
Establish and maintain manufacturing KPIs and performance metrics.
Skills
Demonstrated knowledge of upstream biologics manufacturing, including mammalian cell culture and/or microbial fermentation.
Experience supporting stainless steel and/or single-use bioreactor systems, harvest operations, aseptic processing, and CIP/SIP systems.
Ability to lead manufacturing operations across multiple production areas, shifts, and modalities.
Strong leadership, coaching, and employee development skills.
Effective communication, problem-solving, and decision-making abilities.
Ability to build cross-functional partnerships and drive operational results.
Qualifications & Experience
Required:
Bachelor's degree with 8+ years of industry experience, or Master's degree with 6+ years of industry experience. Equivalent education and experience may be considered.
Experience leading upstream biologics manufacturing operations in a GMP environment.
Experience with mammalian cell culture and/or microbial fermentation manufacturing processes.
Prior experience managing teams in a regulated manufacturing environment.
Formalities
Location: Bothell, WA
Schedule: Full-time
Compensation: $108,080 - $148,610
We offer a comprehensive Total Rewards package that may include annual bonus opportunities, paid time off, medical, dental and vision coverage, parental leave, education assistance, employee referral and recognition programs, and additional wellbeing benefits. Eligibility and benefits may vary based on role, location, and employment status.
Who We Are
AGC Biologics is a global Contract Development and Manufacturing Organization with a strong presence in the United States. From our headquarters in Bothell, Washington, we develop and manufacture life‑changing advanced biologics for some of the world’s most innovative pharmaceutical companies. Together with our team members across Europe, the U.S., and Japan, we deliver development and manufacturing of mammalian and microbial-based therapeutic proteins, plasmid DNA (pDNA), messenger RNA (mRNA), viral vectors, and genetically engineered cells therapies. Across our global network, we are united by one mission: To work side by side with our customers in order to improve patients’ lives by bringing new biopharmaceuticals to market.
We are a collaborative, inclusive, and equal‑opportunity organization where team members are valued for their expertise, teamwork, and ingenuity.
See All 80 Manufacturing Jobs in Washington
Find roles in Washington that match your experience and apply in just a few clicks.
Find Manufacturing JobsManufacturing Jobs by City in Washington
Where Washington roles are concentrated, by current openings.
Manufacturing Job Market in Washington
A snapshot from current Washington openings, updated as new roles post.
Who's Hiring
- Amazon11

- Blue Origin4

- Shield AI3

- nLIGHT3

- Meta2

Top Industries Hiring
- Manufacturing
- Biotechnology & Pharmaceuticals
- Aerospace & Defense
What Washington Employers Look For
The qualifications that appear most often in manufacturing jobs across Washington.
- High school diploma or GED with relevant vocational or technical training preferred
- Experience operating CNC machinery, automated assembly lines, or industrial equipment
- Familiarity with quality control standards such as ISO 9001 or AS9100 in aerospace settings
- Ability to read and interpret technical drawings, blueprints, or engineering specifications
- Knowledge of Lean manufacturing or Six Sigma principles used widely in Washington facilities
- Physical ability to stand for extended periods, lift up to 50 pounds, and work rotating shifts
Manufacturing Jobs in Washington: Frequently Asked Questions
How do you become a manufacturing worker in Washington?
Most manufacturing roles in Washington require a high school diploma or equivalent, though many employers strongly prefer completion of a vocational program at a Washington community or technical college such as Bellingham Technical, Renton Technical, or Spokane Community College. Some specialized roles, such as electrical work within a facility, require a Washington State electrical license issued through the Department of Labor and Industries. Apprenticeship programs through the Washington State Apprenticeship and Training Council offer another structured path into the trades.
Which companies hire manufacturing workers in Washington?
Washington manufacturing roles are posted by Amazon, Blue Origin, and Shield AI and others right now, based on current listings on Migrate Mate as of September 2026. Washington's aerospace, food and beverage processing, and defense sectors consistently drive hiring volume across the state.
Which Washington cities have the most manufacturing jobs?
Seattle, Redmond, and Everett have the most manufacturing openings in Washington right now. The greater Seattle and Everett area is anchored by aerospace and technology manufacturing, Spokane draws from food processing and defense suppliers, and the Tri-Cities region supports agricultural processing and energy-related manufacturing tied to the Hanford Site.
Are there remote manufacturing jobs in Washington?
Yes, but they're rare. Most manufacturing roles require a physical presence on a production floor, warehouse, or facility. About 0% of manufacturing openings tied to Washington are remote or hybrid as of September 2026, reflecting how hands-on the work is by nature. The positions most likely to offer remote or hybrid arrangements are quality assurance documentation roles, supply chain coordination, and manufacturing engineering support functions.
How can I get hired as a manufacturing worker in Washington with little or no experience?
The most realistic entry path is applying for production associate or general assembly roles, which many Washington manufacturers fill without prior experience and train on the job. Boeing's manufacturing apprenticeship program and PACCAR's production hiring pipelines regularly bring in candidates from vocational backgrounds rather than requiring prior factory floor experience. Community and technical colleges across Washington offer short-term certificates in manufacturing technology that give candidates a clear edge. Roles such as warehouse associate, material handler, or quality inspector are common lateral entry points.
Where can I find and apply to manufacturing jobs in Washington?
You can find and apply to manufacturing jobs in Washington on Migrate Mate, which lists current Washington openings across industries and experience levels. Search the listings, find roles that match your background and location, and apply directly to the ones that fit.
See All 80 Manufacturing Jobs in Washington
Find roles in Washington that match your experience and apply in just a few clicks.
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