Medical Technologist Jobs in Minnesota
Medical Technologist jobs in Minnesota are consistently in demand, concentrated in hospital laboratory systems, large integrated health networks, and academic medical centers across the Twin Cities, Rochester, and Duluth. Major employers with deep roots in Minnesota include Mayo Clinic, M Health Fairview, and Allina Health. The most sought-after specialties are clinical chemistry, hematology, microbiology, and blood bank. See the openings below and apply to the ones that match your experience.
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Hennepin Healthcare is an integrated system of care that includes HCMC, a nationally recognized Level I Adult and Pediatric Trauma Center and acute care hospital. The comprehensive healthcare system includes a 484 bed academic medical center, a large outpatient Clinic & Specialty Center, and a network of primary and specialty care clinics in Minneapolis and in suburban communities. Hennepin Healthcare has a large psychiatric program, home care and hospice, and operates a research institute, innovation center and philanthropic foundation.
Equal Employment Opportunities: We believe equity is essential for optimal health outcomes and are committed to achieve optimal health for all by actively eliminating barriers due to racism, poverty, gender identity, and other determinants of health. We are committed to equitable care and working in an environment that celebrates, promotes, and protects diversity, equity, inclusion, and belonging. We are committed to bringing in individuals with new cultural perspectives to assist in creating a more equitable healthcare organization.
JOB DETAILS
Department: Toxicology Lab
FTE: 1.0 (80hours per pay period)
Shift(s): Evenings // rotating weekends and holidays
Location: In-Person
RESPONSIBILITIES
- Follows all laboratory established procedures and processes, including but not limited to patient identification, specimen collection, diagnostic clinical testing, and documentation and data entry into the laboratory information system and /or patient result logs
- Based on training and protocol recognize, document, and communicate unusual and/or critical result values
- Must be competent in (5) work stations or work areas as defined by their section
- Performs and monitors quality control processes, establish and monitor quality assurance and record keeping systems, participates in quality improvement programs, according the standard operating procedures to assure accuracy and validity of test results
- Performs calibration, maintenance, and performance checks on instrumentation according to standard operating procedures and participates in the preparation and evaluation of maintenance schedules and operating procedures for new instrumentation, including writing technical procedures according to regulatory protocol
- Performs troubleshooting processes for instrumentation, reagents, and inventory and/or patient samples as they occur and evaluates methods for solutions
- Takes a leadership role by acting as charge tech when assigned, assisting in the training/teaching of new staff members and /or student interns
Toxicology: In addition to the duties above, Medical Technologists in Toxicology perform the following additional duties:
- Able to perform testing utilizing Gas Chromatography (GC), Liquid Chromatography (LC), and Mass Spectrometry (MS)
- Able to discuss the theory of and perform Therapeutic Drug Monitoring (TDM) testing
- Able to perform testing utilizing Chain of Custody documentation and procedures
QUALIFICATIONS
Minimum Qualifications:
- Bachelor's degree in medical technology, clinical laboratory science or Medical Laboratory Science
- Completion of a CLS/MLS/MT training program approved by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS),
-OR-
- An approved equivalent combination of education and experience
For Medical Technologists in Toxicology:
- Current certification as a Medical Technologist MT(ASCP), Clinical Laboratory Scientist CLS(NCA), or Medical Laboratory Scientist MLS (ASCP), or Chemistry Technologist C(ASCP)
-OR-
- Eligible for certification as a Medical Laboratory Scientist MLS (ASCP)
- As a condition of employment, those hired “as eligible” must take the first available examination after their date of hire and pass one of these certifying exams within three consecutive administrations of the exam within a 12 month period
-OR-
- Eligible for certification as a Chemistry Technologist C (National Registry of Certified Chemists)
- As a condition of employment, those hired “as eligible” must take the first available examination after one year of employment and pass the certifying exam within two consecutive administrations of the exam within a 6 month period. (Certified within 24 months of hire date)
Preferred Qualifications:
- One year experience
Knowledge/ Skills/ Abilities:
- Customer service skills
You've made the right choice in considering Hennepin Healthcare for your employment. We offer a wealth of opportunities for individuals who want to make an impact in our patients' lives. We are dedicated to providing Equal Employment Opportunities to both current and prospective employees. We are driven to connect talented individuals with life-changing career opportunities, enabling you to provide exceptional care without exception. Thank you for considering Hennepin Healthcare as a future employer.
Please Note: Offers of employment from Hennepin Healthcare are conditional and contingent upon successful clearance of all background checks and pre-employment requirements.
- We offer a competitive pay rate based on your skills, licensure/certifications, education, experience related to this position, and internal equity.
- We provide an extensive benefits program that includes Medical; Dental; Vision; Life, Short and Long-term Term Disability Insurance; Retirement Funds; Paid Time Off; and Tuition reimbursement.
- For a complete list of our benefits, please visit our career site on why you should work for us.
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Where Minnesota roles are concentrated, by current openings.
Medical Technologist Job Market in Minnesota
A snapshot from current Minnesota openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Education
- Healthcare & Medical Services
What Minnesota Employers Look For
The qualifications that appear most often in medical technologist jobs across Minnesota.
- Active Minnesota medical laboratory technologist licensure through the Minnesota Department of Health
- Bachelor's degree in medical laboratory science or a closely related field
- ASCP Board of Certification or equivalent national certification required or preferred
- Proficiency with laboratory information systems such as Epic Beaker or Sunquest
- Experience in one or more core disciplines including chemistry, hematology, or microbiology
- Ability to work rotating shifts including evenings, weekends, and holidays as required
Medical Technologist Jobs in Minnesota: Frequently Asked Questions
How do you become a medical technologist in Minnesota?
Minnesota requires medical laboratory personnel to hold a state license issued through the Minnesota Department of Health, which oversees laboratory personnel licensing for the state. To qualify, you need a bachelor's degree in medical laboratory science or a related life science field and national certification, most commonly through the ASCP Board of Certification. After submitting your application and documentation to the Minnesota Department of Health, you receive a state license that employers verify before hire.
Which companies hire medical technologists in Minnesota?
Employers hiring medical technologists in Minnesota right now include Mayo Clinic, Hennepin Healthcare, and Winona Health, based on current listings on Migrate Mate as of August 2026. Minnesota's large integrated health systems and the concentration of specialty care around the Mayo Clinic in Rochester and the Twin Cities metro drive consistent year-round hiring across disciplines.
Which Minnesota cities have the most medical technologist jobs?
The cities with the most medical technologist openings in Minnesota are Minneapolis, Austin, and Winona. The Twin Cities metro drives volume through its dense cluster of hospital systems and academic medical centers, while Rochester's openings are anchored heavily by Mayo Clinic, one of the largest laboratory employers in the country, and Duluth benefits from regional health systems serving both the city and the broader Lake Superior area.
How can I get hired as a medical technologist in Minnesota with little or no experience?
The most realistic entry path is applying directly to new-graduate laboratory scientist programs at large Minnesota health systems such as Mayo Clinic, M Health Fairview, and Allina Health, which regularly onboard candidates who are newly certified. Many candidates also enter through adjacent roles such as laboratory assistant or phlebotomist while completing their degree, then transition internally once licensed. Holding your Minnesota Department of Health license and ASCP certification before applying gives you a clear edge over candidates still awaiting credentials.
Where can I find and apply to medical technologist jobs in Minnesota?
You can find and apply to medical technologist jobs in Minnesota on Migrate Mate, which lists current Minnesota openings. Search the listings, find roles that match your specialty and experience level, and apply directly to the ones that fit.
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