Clinic Registered Nurse Jobs in Minnesota
Clinic Registered Nurse jobs in Minnesota are concentrated in the Twin Cities metro, Rochester, and Duluth, where major systems like Mayo Clinic, M Health Fairview, and HealthPartners maintain large outpatient and specialty clinic networks. Demand is strongest in primary care, pediatrics, and chronic disease management, with openings at every level from new-grad to experienced ambulatory care. Minnesota's well-developed integrated health system creates steady clinic hiring across both urban campuses and suburban care sites. See the openings below and apply to the ones that match your experience.
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Careers With Purpose
Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.
Facility: East Grand Forks Clinic 625 Demers Clinic
Location: East Grand Forks, MN
Address: 625 Demers Ave, East Grand Forks, MN 56721, USA
Shift: 8 Hours - Day Shifts
Job Schedule: Full time
Weekly Hours: 40.00
Salary Range: $29.50 - $44.50
Pay Info: Sign on bonus available!
Department Details
Join our friendly, close knit team at the East Grand Forks Dermatology Clinic as a full time registered nurse (RN)!
In this role, you'll partner with our dermatology team to set up and prep for Mohs surgery, assist with procedures within your scope of practice along with restarting home sleep studies and heart screens.
Hours are Mon - Fri 8:00am - 5:00pm with no nights, weekends, or major federal holidays.
$15,000 sign on bonus available for eligible new hires!
If you're looking for variety in your day, strong team support, and the chance to make a real impact in a rural community, this is the perfect opportunity for you!
Job Summary
Responsible for the coordination of care, patient assessment, patient education, triage, and various other interventions. We are seeking a compassionate and skilled Registered Nurse (RN) to join our clinic team. Registered nurses who thrive are adaptable, great communicators, detail-oriented and have excellent time management skills. This role collaborates with providers and assists during surgical and non-surgical procedures.
Your day to day may include:
Providing individualized and hands on care
Utilizing nursing and assessment skills
Patient and family education
In clinic procedures
Available for you:
A supportive team dedicated to patient-centered care
Specialized on-boarding and on the job training
Continued growth and development as a RN
Fun and fast paced work environment
Qualifications
Graduate from an accredited nursing program required, including, but not limited to, American Association of Colleges of Nursing (AACN), Accreditation Commission for Education in Nursing (ACEN), and National League for Nursing Commission for Nursing Education Accreditation (NLN CNEA). Bachelor’s Degree in nursing preferred.
Currently holds an unencumbered RN license with the State Board of Nursing where the practice of nursing is occurring and/or possess multistate licensure if in a Nurse Licensure Compact (NLC) state. Obtains and subsequently maintains required department specific licensure, competencies and certifications.
Benefits
Sanford offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, and a generous time off package to maintain a healthy home-work balance. For more information about Total Rewards, visit https://sanfordcareers.com/benefits .
Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to talent@sanfordhealth.org .
Sanford has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment.
Req Number: R-0272026
Job Function: Nursing
Featured: No
See All 37 Clinic Registered Nurse Jobs in Minnesota
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Find Clinic Registered Nurse JobsClinic Registered Nurse Jobs by City in Minnesota
Where Minnesota roles are concentrated, by current openings.
Clinic Registered Nurse Job Market in Minnesota
A snapshot from current Minnesota openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Education
- Insurance
- Technology & Software
What Minnesota Employers Look For
The qualifications that appear most often in clinic registered nurse jobs across Minnesota.
- Active registered nurse license issued or recognized by the Minnesota Board of Nursing
- Associate or bachelor's degree in nursing from an accredited program
- Current BLS certification and often ACLS depending on clinic specialty
- At least one year of clinical nursing experience in an outpatient or ambulatory setting
- Proficiency with electronic health record systems such as Epic or Cerner
- Strong patient education skills and experience managing chronic condition populations
Clinic Registered Nurse Jobs in Minnesota: Frequently Asked Questions
How do you become a clinic registered nurse in Minnesota?
You become a clinic registered nurse in Minnesota by earning an associate or bachelor's degree in nursing, passing the NCLEX-RN exam, and obtaining an active RN license through the Minnesota Board of Nursing. Minnesota participates in the Nurse Licensure Compact, so nurses licensed in other compact states can practice in Minnesota without a separate state license. Most clinic roles also expect relevant clinical experience before hire, though new-grad positions exist at larger integrated systems.
How much do clinic registered nurses make in Minnesota?
Clinic registered nurses in Minnesota earn a median of about $101,510 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $79,960 for the lowest 10% to over $132,430 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinic registered nurses in Minnesota?
Companies currently hiring clinic registered nurses in Minnesota include Sanford Health, Mayo Clinic, and Allina Health, per current listings on Migrate Mate as of August 2026. Minnesota's large integrated health systems operate extensive outpatient clinic networks across the Twin Cities, Rochester, and smaller regional markets, making them the most consistent sources of clinic RN openings in the state.
Which Minnesota cities have the most clinic registered nurse jobs?
Rochester, Saint Paul, and Onamia have the most clinic registered nurse openings in Minnesota. The Twin Cities metro drives the largest share of listings because of the concentration of major health system headquarters and specialty clinic campuses there, while Rochester's volume reflects Mayo Clinic's vast ambulatory care operations and Duluth serves as the regional hub for northeastern Minnesota's clinic network.
Are there remote clinic registered nurse jobs in Minnesota?
Yes, but they're rare. About 0% of clinic registered nurse openings tied to Minnesota are remote or hybrid as of August 2026, reflecting how hands-on the role is by nature. The portions of clinic nursing most likely to involve remote or hybrid work are telephone triage, care coordination, and chronic disease management coaching, where patient interaction happens primarily over phone or video.
How can I get hired as a clinic registered nurse in Minnesota with little or no experience?
The most realistic entry path is applying to new-graduate or nurse residency programs at large Minnesota health systems such as Mayo Clinic, M Health Fairview, or HealthPartners, which run structured ambulatory care onboarding tracks for nurses without outpatient experience. Candidates coming from inpatient roles like med-surg or pediatrics often transition successfully into clinic settings. A current Minnesota RN license and Epic experience give applicants a meaningful edge during the selection process.
Where can I find and apply to clinic registered nurse jobs in Minnesota?
You can find and apply to clinic registered nurse jobs in Minnesota on Migrate Mate, which lists current Minnesota openings across clinic settings and specialties. Search the listings to find roles that match your experience level and preferred location, then apply directly to the ones that fit.
See All 37 Clinic Registered Nurse Jobs in Minnesota
Find roles in Minnesota that match your experience and apply in just a few clicks.
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