Pharmacist Jobs in South Carolina
Pharmacist jobs in South Carolina draw steady demand from retail chains, hospital systems, and specialty care networks, with openings at every level from new-graduate staff pharmacist to clinical pharmacy director. Columbia, Greenville, and Charleston are the state's primary hiring centers, anchored by large employers such as Prisma Health, MUSC Health, and Walmart Pharmacy. The most consistent openings are in clinical pharmacy, ambulatory care, and long-term care settings. See the openings below and apply to the ones that match your experience.
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Publix is continually recognized as one of the best places in America to work; see why Publix should be part of your list of top places to work in Pharmacy. And, with growth potential of up to 50 new pharmacies per year, our promote from within culture allows for a rewarding career path into any one of the following areas: retail management, specialty pharmacy, out-patient hospital pharmacy, corporate or centralized pharmacy operations.
Your passion for health and wellness, combined with our reputation and commitment to excellence, are what sets Publix apart from the crowd. We know you want to make a career out of caring. We want your career to be with Publix Pharmacy. Join the team that pharmacists and patients feel good about.
In addition to the shared basic responsibilities of all Publix associates, a Floating Pharmacist’s responsibilities include, but are not limited to, the following. As a Floating Pharmacist, you will:
- provide dedication to each pharmacies success, by executing strategy, motivating and inspiring staff as the pharmacist-on-duty
- set priorities to maximize contribution, executing daily tasks, supporting the team and building rapport with both customers and associates
- provide best-in-class pharmacy service to patients, empower your staff in providing value and service through counseling, building personalized relationships, promoting customer loyalty, offering pharmacist led clinical services to improve health and wellness and preventative care through services available at Publix
- inspire each team you work with to do the right thing, gaining buy in, and empowering the team to be accountable
- provide enthusiasm for all new pharmacy initiatives at your assigned location
- manage team performance, such as prescription promised time, by assigning tasks to ensure complex operational activities are met in a timely and efficient manner in the absence of the pharmacist-in-charge
- use best practices to make sound business decisions while covering as the pharmacist-on-duty
- be regarded as an expert on the pharmacy technology system and how it is used for both routine and complex prescription processing
- mentor others on Publix pharmacy best practices to maximize sales, minimize shrink while meeting customers’ needs, using programs such as auto refill and Sync Your Refills
- proactively advance pharmacy clinical initiatives including Medication Therapy Management (MTM) and immunizations
- maintain a flexible work-week schedule in order to meet the needs of our customers, and
- assist in all other duties as assigned.
See All 58 Pharmacist Jobs in South Carolina
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Find Pharmacist JobsPharmacist Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Pharmacist Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- CVS Health26

- Walgreens6

- Walmart4

- Publix3

- McLeod Health2

Top Industries Hiring
- Retail
- Insurance
What South Carolina Employers Look For
The qualifications that appear most often in pharmacist jobs across South Carolina.
- Active pharmacist license issued or recognized by the South Carolina Board of Pharmacy
- Doctor of Pharmacy degree from an ACPE-accredited college of pharmacy
- Successful completion of NAPLEX and MPJE licensing examinations
- Experience with pharmacy dispensing software and electronic health records
- Strong clinical knowledge in one or more therapeutic areas such as oncology or cardiology
- Current immunization certification or willingness to obtain one upon hire
Pharmacist Jobs in South Carolina: Frequently Asked Questions
How do you become a pharmacist in South Carolina?
You must earn a Doctor of Pharmacy degree from an accredited program, pass the NAPLEX and MPJE exams, and obtain a license from the South Carolina Board of Pharmacy. The Board also requires a background check and completion of a supervised internship before licensure. Pharmacists licensed in another state may apply for licensure by endorsement through the same Board.
How much do pharmacists make in South Carolina?
Pharmacists in South Carolina earn a median of about $135,700 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $82,430 for the lowest 10% to over $170,270 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire pharmacists in South Carolina?
South Carolina pharmacist roles are posted by CVS Health, Walgreens, and Walmart and others right now, based on current listings on Migrate Mate as of August 2026. Major health systems like Prisma Health and MUSC Health, alongside retail chains, account for a large share of ongoing openings across the state.
Which South Carolina cities have the most pharmacist jobs?
Columbia, Charleston, and Taylors lead South Carolina in pharmacist openings. Columbia's concentration of large hospital systems and state government health facilities drives volume there, while Greenville's growing Upstate medical corridor and Charleston's academic medical center at MUSC Health sustain consistent demand in those metros.
Are there remote pharmacist jobs in South Carolina?
Yes, but they're rare. About 0% of pharmacist openings tied to South Carolina are remote or hybrid as of August 2026, reflecting how hands-on dispensing and patient-facing responsibilities keep most roles on-site. The positions most likely to allow remote work are telepharmacy, utilization review, and prior authorization roles.
How can I get hired as a pharmacist in South Carolina with little or no experience?
The most realistic entry path is completing a postgraduate pharmacy residency, and both Prisma Health and MUSC Health run accredited PGY-1 residency programs in South Carolina for new graduates. Retail pharmacy technician roles at major chains also offer a bridge into staff pharmacist positions once licensure is secured. Candidates who have finished their IPPE and APPE rotations in South Carolina institutions and hold an active intern registration with the South Carolina Board of Pharmacy move to the front of the line.
Where can I find and apply to pharmacist jobs in South Carolina?
You can find and apply to pharmacist jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the listings, find the roles that fit your experience and preferred location, and apply directly to the ones that match.
See All 58 Pharmacist Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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