Physician Substitute Jobs
Physician substitute jobs are open across primary care, urgent care, rural health, and hospital systems, from locum tenens to permanent placement, with specializations in internal medicine, family practice, and emergency care. Find a role that fits below and apply directly.
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KEDPLASMA is a subsidiary of Kedrion Biopharma Inc. KEDPLASMA specializes in the collection and procurement of high-quality plasma that is processed into plasma-based therapies. Kedrion Biopharma Inc. is an international company specializing in the collection and fractionation of blood plasma to produce and distribute plasma-derived therapeutic products. Our therapies help treat and prevent serious diseases, including Hemophilia, Primary Immune System Deficiencies, and Rh-Sensitization.
Job Summary
Are you a healthcare professional (EMT, LPN/LVN, or RN) looking to make a difference in a unique clinical setting? Join our team and play a vital role in ensuring donor safety and supporting the plasma donation process. This is a great opportunity to apply your clinical expertise in a fast-paced, mission-driven environment.
When you join our team, you’ll be responsible for evaluating donor eligibility, managing medical incidents, and supporting the overall health and safety of donors. You’ll work closely with the Center Medical Director and other team members to ensure compliance with regulatory standards and provide a positive donor experience.
What you'll do
- Perform physical exams and assess donor eligibility for plasmapheresis and immunization programs.
- Review donor health history and lab results to determine suitability, consulting with the Center Medical Director as needed.
- Educate donors on the donation process, risks, benefits, and informed consent, ensuring they understand and feel comfortable.
- Administer immunizations and monitor adverse reactions, documenting all procedures accurately.
- Respond to donor reactions (e.g., hypotensive, citrate, allergic) with appropriate treatment and escalate when necessary.
- Maintain and monitor emergency medical equipment and ensure readiness for any situation.
- Notify donors of positive viral marker results (e.g., Hepatitis B/C, HIV, Syphilis) and provide confidential counseling.
- Participate in safety committee activities and educate staff on donor suitability and medical protocols.
- Manage employee immunization programs and ensure compliance with SOPs and regulatory guidelines.
- Assist with plasmapheresis and whole blood procedures when needed.
- Maintain accurate documentation in donor charts and ensure all medical incidents are reviewed appropriately.
- Promote donor retention by creating a welcoming, informative, and safe experience.
Qualifications and need-to-know
- Must be currently licensed to practice in the state where the center operates.
- Acceptable licenses include EMT-B, EMT-I, EMT-A, Paramedic, LPN, LVN, or RN (accepted for hires prior to May 30, 2019).
- Graduate of a recognized healthcare-related educational program (e.g., Nursing, Physician Assistant, or advanced EMT).
- Current CPR certification.
- At least 1 year of experience in a healthcare setting is preferred.
- Experience in plasma or blood collection is a plus.
- Strong interpersonal skills and a commitment to donor care and safety.
- Ability to remain calm and professional in high-pressure situations.
- Familiarity with FDA, OSHA, CLIA, and cGMP regulations is beneficial.
- Comfortable working in a regulated environment with exposure to bloodborne pathogens and cold storage areas.
Employment eligibility verification will be required at the time of hire. This position does not offer visa sponsorship now or in the future.
Kedrion Biopharma Inc. is committed to providing equal employment opportunities to all employees and applicants. We prohibit discrimination and harassment based on race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws. This policy applies to all employment terms, including recruitment, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.
Salary ranges are determined based on relevant experience, education, and certifications.
If you require assistance with your employment application or need reasonable accommodations to perform job duties, please contact our Talent Acquisition team at kedtalent@kedrion.com.
Employee Benefits: At Kedrion Biopharma Inc., we believe in taking care of our people. Our benefits package is designed to support your health, happiness, and future, including:
- Health & Wellness – Full medical, dental, and vision coverage
- Financial Security – Life insurance, AD&D, and retirement savings plans
- Work-Life Balance – Paid time off, sick leave, and paid holidays
- Career Growth – Training programs and development opportunities
- Extra Perks – Employee discounts, wellness initiatives, and more!
For specific inquiries please reach out to us
Kedrion Biopharma Inc. participates in E-Verify and provides the federal government with Form I-9 information to confirm employment authorization. For more information, please contact the Department of Homeland Security.
KEDPLASMA is a subsidiary of Kedrion Biopharma Inc. KEDPLASMA specializes in the collection and procurement of high-quality plasma that is processed into plasma-based therapies. Kedrion Biopharma Inc. is an international company specializing in the collection and fractionation of blood plasma to produce and distribute plasma-derived therapeutic products. Our therapies help treat and prevent serious diseases, including Hemophilia, Primary Immune System Deficiencies, and Rh-Sensitization.
Job Summary
Are you a healthcare professional (EMT, LPN/LVN, or RN) looking to make a difference in a unique clinical setting? Join our team and play a vital role in ensuring donor safety and supporting the plasma donation process. This is a great opportunity to apply your clinical expertise in a fast-paced, mission-driven environment.
When you join our team, you’ll be responsible for evaluating donor eligibility, managing medical incidents, and supporting the overall health and safety of donors. You’ll work closely with the Center Medical Director and other team members to ensure compliance with regulatory standards and provide a positive donor experience.
What you'll do
- Perform physical exams and assess donor eligibility for plasmapheresis and immunization programs.
- Review donor health history and lab results to determine suitability, consulting with the Center Medical Director as needed.
- Educate donors on the donation process, risks, benefits, and informed consent, ensuring they understand and feel comfortable.
- Administer immunizations and monitor adverse reactions, documenting all procedures accurately.
- Respond to donor reactions (e.g., hypotensive, citrate, allergic) with appropriate treatment and escalate when necessary.
- Maintain and monitor emergency medical equipment and ensure readiness for any situation.
- Notify donors of positive viral marker results (e.g., Hepatitis B/C, HIV, Syphilis) and provide confidential counseling.
- Participate in safety committee activities and educate staff on donor suitability and medical protocols.
- Manage employee immunization programs and ensure compliance with SOPs and regulatory guidelines.
- Assist with plasmapheresis and whole blood procedures when needed.
- Maintain accurate documentation in donor charts and ensure all medical incidents are reviewed appropriately.
- Promote donor retention by creating a welcoming, informative, and safe experience.
Qualifications and need-to-know
- Must be currently licensed to practice in the state where the center operates.
- Acceptable licenses include EMT-B, EMT-I, EMT-A, Paramedic, LPN, LVN, or RN (accepted for hires prior to May 30, 2019).
- Graduate of a recognized healthcare-related educational program (e.g., Nursing, Physician Assistant, or advanced EMT).
- Current CPR certification.
- At least 1 year of experience in a healthcare setting is preferred.
- Experience in plasma or blood collection is a plus.
- Strong interpersonal skills and a commitment to donor care and safety.
- Ability to remain calm and professional in high-pressure situations.
- Familiarity with FDA, OSHA, CLIA, and cGMP regulations is beneficial.
- Comfortable working in a regulated environment with exposure to bloodborne pathogens and cold storage areas.
Employment eligibility verification will be required at the time of hire. This position does not offer visa sponsorship now or in the future.
Kedrion Biopharma Inc. is committed to providing equal employment opportunities to all employees and applicants. We prohibit discrimination and harassment based on race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws. This policy applies to all employment terms, including recruitment, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.
Salary ranges are determined based on relevant experience, education, and certifications.
If you require assistance with your employment application or need reasonable accommodations to perform job duties, please contact our Talent Acquisition team at kedtalent@kedrion.com.
Employee Benefits: At Kedrion Biopharma Inc., we believe in taking care of our people. Our benefits package is designed to support your health, happiness, and future, including:
- Health & Wellness – Full medical, dental, and vision coverage
- Financial Security – Life insurance, AD&D, and retirement savings plans
- Work-Life Balance – Paid time off, sick leave, and paid holidays
- Career Growth – Training programs and development opportunities
- Extra Perks – Employee discounts, wellness initiatives, and more!
For specific inquiries please reach out to us
Kedrion Biopharma Inc. participates in E-Verify and provides the federal government with Form I-9 information to confirm employment authorization. For more information, please contact the Department of Homeland Security.
Physician Substitute Jobs by Experience Level
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Find Physician Substitute JobsPhysician Substitute Job Market
Who's Hiring
- Join Parachute25
- KEDPlasma5
- Saint Johns Catholic Church2S
- Kamada1
- ADMA Biologics1
What Employers Look For
The qualifications that appear most often in physician substitute jobs.
- Current state medical licensure or physician associate certification required
- Board certification or board eligibility in a primary specialty
- Active DEA registration for controlled substance prescribing
- Minimum two years of clinical experience in a relevant care setting
- BLS and ACLS certification current at time of hire
- Experience with electronic health record systems in a clinical environment
Tips for Your Physician Substitute Job Search
Tailor your resume for each setting
Physician substitute roles in urgent care demand different skills than rural primary care or hospital inpatient coverage. Rewrite your summary and bullet points to match the clinical setting in each posting, not just the job title.
Highlight your scope of practice clearly
Employers need to know immediately what procedures you can perform independently and where supervising physician requirements apply. Put your state-specific scope of practice and any collaborative agreement details near the top of your resume.
Apply early to roles that fit
Migrate Mate lists physician substitute openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare for clinical scenario questions
Interviews for physician substitute positions almost always include case-based questions testing your independent decision-making. Practice walking through your diagnostic and treatment reasoning out loud, especially for high-acuity presentations you'd manage without immediate backup.
Get your credentials verified before you apply
Many physician substitute postings require DEA registration, state licensure, and board certification to be active and verifiable before an offer is extended. Confirm your primary source verifications are current so credentialing doesn't delay your start date.
Negotiate schedule terms, not just compensation
Coverage ratios, on-call frequency, and patient panel size affect your workload far more than base pay alone. When you receive an offer, ask specifically how many patients you're expected to see per shift and what after-hours responsibilities are included.
Physician Substitute Jobs: Frequently Asked Questions
Which companies are hiring the most physician substitutes?
The companies hiring the most physician substitutes right now include Join Parachute, KEDPlasma, and Saint Johns Catholic Church, with the largest share of openings in Maryland, Georgia, and Arkansas, based on current listings on Migrate Mate as of November 2026. Rural health systems and urgent care networks tend to post the highest volume of openings consistently.
How many physician substitute jobs are remote?
About 0% of physician substitute openings are fully remote or hybrid as of November 2026, reflecting the hands-on nature of most clinical roles. Telehealth-focused positions in chronic disease management and behavioral health integration represent the sub-areas with the highest share of remote opportunities.
How do you become a physician substitute?
To become a physician substitute, complete an accredited physician assistant or medical degree program, pass your national licensing examination, and obtain a state medical license in the states where you plan to practice. Secure a DEA registration if you will prescribe controlled substances, and pursue board certification in your primary specialty to strengthen your candidacy for independent or supervisory roles.
How do you get hired as a physician substitute with little experience?
Start by targeting roles at federally qualified health centers, rural health clinics, and urgent care chains, which are more likely to hire new graduates and provide structured onboarding. Emphasize your clinical rotation hours in underserved or high-volume settings, obtain your DEA number before applying, and be flexible about geographic location, since less competitive markets move candidates through the hiring process faster.
What does the physician substitute interview process look like?
The process typically begins with a phone or video screen by a physician leader or department director, followed by an on-site or virtual clinical interview that includes patient scenario questions and a review of your prescribing approach. Final stages often involve a credentialing review, a tour of the facility or shadow shift, and a committee decision before an offer is extended.
Where can I find and apply to physician substitute jobs?
You can find and apply to physician substitute jobs on Migrate Mate, which lists current openings from across the United States. Search the listings to find roles that match your specialty, preferred setting, and location, then apply directly to each opening that fits.
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