Principal Scientist Jobs in Mississippi

Principal Scientist jobs in Mississippi are concentrated in pharmaceutical research, agrochemical development, and federal contract science, with demand steady across mid-career to director-adjacent levels. Jackson, Oxford, and the Gulf Coast corridor around Gulfport and Biloxi account for the largest share of openings, anchored by employers such as the University of Mississippi Medical Center, Chemours, and Tetra Tech. Regulatory affairs, analytical chemistry, and environmental science are the most consistently sought specialties across Mississippi's research and industry sectors. See the openings below and apply to the ones that match your experience.

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Overview

Open roles16
Top employerUniversity of Mississippi Medical Center
Top cityJackson, MS
Cities hiring7
Work type100% On-site
Top industryHealthcare

Showing 5 of 16+ Principal Scientist jobs

Singing River Health System
Medical Laboratory Technician (MLT) or Medical Laboratory Scientist (MLS) | Laboratory | Days
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Singing River Health System
New 1m ago
Medical Laboratory Technician (MLT) or Medical Laboratory Scientist (MLS) | Laboratory | Days
Singing River Health System
Pascagoula, Mississippi
Clinical Support
Healthcare Administration
Project Management
Associate's degree in Medical Laboratory Technology
1,001-5,000

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Singing River Health System
Medical Laboratory Scientist | Lab - Blood Bank
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Singing River Health System
New 1m ago
Medical Laboratory Scientist | Lab - Blood Bank
Singing River Health System
Pascagoula, Mississippi
Clinical Support
Healthcare Administration
Project Management
Medical Laboratory Scientist Certification
1,001-5,000

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Singing River Health System
Medical Laboratory Scientist | Lab - Hematology
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Singing River Health System
New 1m ago
Medical Laboratory Scientist | Lab - Hematology
Singing River Health System
Gulfport, Mississippi
Clinical Support
Healthcare Administration
Project Management
Medical Laboratory Scientist Certification
1,001-5,000

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Singing River Health System
Medical Laboratory Scientist | Lab - Blood Bank
We won't show you this job again
Singing River Health System
New 1m ago
Medical Laboratory Scientist | Lab - Blood Bank
Singing River Health System
Gulfport, Mississippi
Clinical Support
Healthcare Administration
Project Management
Medical Laboratory Scientist Certification
1,001-5,000

Have you applied for this role?

Methodist Le Bonheur Healthcare
Med Lab Scientist III | Olive Branch | Nights
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Methodist Le Bonheur Healthcare
New 1m ago
Med Lab Scientist III | Olive Branch | Nights
Methodist Le Bonheur Healthcare
Olive Branch, Mississippi
Biotech & Life Sciences
Clinical Support
Laboratory Science
Medical Laboratory Scientist Certification
10,000+

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Principal Scientist Jobs by City in Mississippi

Where Mississippi roles are concentrated, by current openings.

Jackson
6 jobs
Stennis Space Center
3 jobs
Gulfport
2 jobs
Pascagoula
2 jobs
Morton
1 job
Horn Lake
1 job
Olive Branch
1 job

Principal Scientist Job Market in Mississippi

A snapshot from current Mississippi openings, updated as new roles post.

Who's Hiring

  • University of Mississippi Medical Center
    University of Mississippi Medical Center5
  • Singing River Health System
    Singing River Health System4
  • Leidos
    Leidos1
  • Onterris
    Onterris1
  • Tetra Tech
    Tetra Tech1

Top Industries Hiring

  • Healthcare & Medical Services4
  • Education2
  • Technology & Software1

What Mississippi Employers Look For

The qualifications that appear most often in principal scientist jobs across Mississippi.

  • PhD in chemistry, biology, environmental science, or a closely related scientific field
  • Minimum eight years of progressive research or applied science experience
  • Demonstrated record of leading cross-functional research projects from design through publication
  • Experience with regulatory submissions including EPA, FDA, or USDA compliance frameworks
  • Proficiency with statistical analysis software such as SAS, R, or JMP
  • Strong technical writing skills for scientific reports, grant proposals, and peer-reviewed manuscripts

Principal Scientist Jobs in Mississippi: Frequently Asked Questions

How do you become a principal scientist in Mississippi?

Most principal scientist roles in Mississippi require a doctoral degree in a relevant scientific discipline and substantial postdoctoral or industry research experience. Mississippi does not maintain a state-issued license specifically for the principal scientist title, so employers set their own standards. Candidates who have published peer-reviewed research, led grant-funded projects, or hold professional credentials such as Certified Environmental Professional through the Academy of Board Certified Environmental Professionals are consistently competitive in Mississippi's market.

Which companies hire principal scientists in Mississippi?

Employers hiring principal scientists in Mississippi right now include University of Mississippi Medical Center, Singing River Health System, and Leidos, based on current listings on Migrate Mate as of July 2026. Mississippi's mix of research universities, federal facilities such as the Army Corps of Engineers research center in Vicksburg, and Gulf Coast environmental consultancies creates a varied employer base across the state.

Which Mississippi cities have the most principal scientist jobs?

Jackson, Stennis Space Center, and Gulfport account for the most principal scientist openings in Mississippi. Jackson dominates because of the University of Mississippi Medical Center and state agency research divisions, while Oxford benefits from the University of Mississippi's research programs, and Gulf Coast cities like Gulfport draw openings tied to federal environmental and defense contractors operating along the coast.

Are there remote principal scientist jobs in Mississippi?

Yes, but they're rare. About 0% of principal scientist openings tied to Mississippi are remote or hybrid as of July 2026, reflecting how much of the work involves laboratory equipment, field sampling, or on-site collaboration. The portions of the role most likely to be performed remotely are data analysis, manuscript preparation, and regulatory writing for scientists whose bench work is handled by supporting staff.

How can I get hired as a principal scientist in Mississippi with little or no experience?

The most realistic entry path is a postdoctoral research appointment, and the University of Mississippi, Mississippi State University, and the University of Mississippi Medical Center all run active postdoc programs across life sciences, chemistry, and public health. From there, candidates typically move into associate or staff scientist roles before advancing. Building a publication record, securing even a co-investigator credit on a federal grant, and earning a Certified Environmental Professional credential if your background is environmental all accelerate that progression within Mississippi institutions.

Where can I find and apply to principal scientist jobs in Mississippi?

You can find and apply to principal scientist jobs in Mississippi on Migrate Mate, which lists current openings from employers across the state. Search the listings to find roles that match your specialty and experience level, then apply directly to the ones that fit.

See All 16 Principal Scientist Jobs in Mississippi

Find roles in Mississippi that match your experience and apply in just a few clicks.

Find Principal Scientist Jobs