Process Engineer Jobs in Maryland
Process engineer jobs in Maryland are concentrated in biotechnology, pharmaceuticals, defense manufacturing, and chemical processing, with demand steady across junior, mid-level, and senior roles. The largest hiring activity is in and around Baltimore, Rockville, and Gaithersburg, where companies like Lockheed Martin, AstraZeneca, and W. R. Grace have long-established operations. Bioprocess and pharmaceutical manufacturing engineering are among the most in-demand specializations in the state, driven by Maryland's dense corridor of life sciences employers. See the openings below and apply to the ones that match your experience.
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Position Summary
We are seeking a highly motivated Senior Process Engineer to support cell therapy process characterization and commercialization activities. In this role, you will play critical role in advancing late-stage cell therapy process development, process characterization, PPQ readiness, BLA‑enabling studies, and technology transfer to different manufacturing sites. This position focuses specifically on cell therapy unit operations, including T-cell enrichment, activation, transduction, washes and harvest either semi-automated or automated equipment.
The ideal candidate brings deep technical expertise, hands-on experience with cell therapy unit operations, and demonstrates success in supporting clinical and commercial readiness.
Key Responsibilities
Process development and characterization
- Design, execute, and support autologous or allogenic cell therapy process optimization and robustness studies.
- Drive implementation of closed-system operations and automation strategies to support scalability and compliance.
- Plan and execute process characterization studies (DOE, multivariate studies, scale‑down models, and scale‑up assessments) in alignment with QbD and ICH guidelines.
- Perform risk assessment, data analysis, write technical reports, and present outcome of the studies to cross‑functional teams and governance forums.
- Support development and refinement of control strategies for cell therapy processes, including raw materials, and cell therapy process parameters.
- Conduct batch record review, deviation assessment, and data trending to ensure robustness of cell therapy manufacturing processes.
- Apply AI‑enabled tools and digital analytics to accelerate data review, trend analysis, batch record evaluation, and process understanding.
PPQ, Tech Transfer & Manufacturing Readiness
- Contribute to PPQ planning, readiness, execution, and documentation for cell therapy processes.
- Support technology transfer of cell therapy processes to internal manufacturing sites including make-a-batch assessments and drafting manufacturing batch record.
- Provide on‑the‑floor technical support during scale‑up, engineering runs, PPQ batches, and commercial manufacturing campaigns (including off‑shift support when required).
- Support raw material risk assessments, comparability studies, and process risk evaluations across facilities and platforms.
Regulatory Support
- Contribute to authoring and reviewing CMC documentation, including cell therapy process descriptions, characterization summaries, PPQ protocols and reports, and control strategy elements.
- Support preparation of BLA/MAA submissions and responses to regulatory questions related to cell therapy manufacturing.
Cross‑Functional Collaboration
- Work closely with analytical sciences, quality, regulatory, and manufacturing teams to ensure end‑to‑end process alignment.
- Represent cell therapy characterization activities in technical meetings, reviews, and governance discussions.
- Support lifecycle management, post‑approval changes, and continuous improvement initiatives for cell therapy processes.
Required Qualifications
- Ph.D. in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field with 2+ years of industry experience; OR M.S. with 5+ years; OR B.S. with 7+ years of hands‑on industry experience.
- Strong technical expertise in key cell therapy unit operations (e.g., cell isolation, activation, transduction, expansion, harvest, formulation, cryopreservation).
- Demonstrated experience with GMP operations and late‑stage / commercial readiness.
- Proven ability to analyze complex datasets, develop sound recommendations, and communicate clearly across levels
- Experience with late‑stage development, process characterization, and PPQ principles for cell therapy processes.
- Demonstrated proficiency in applying AI tools and digital solutions to data analysis, documentation, and workflow automation.
- Experience working in GMP environments, including batch record execution or review, deviations, and investigations.
- Strong technical writing, data analysis, and problem‑solving skills.
Preferred Qualifications
- Experience with viral vector handling (Lentivirus, AAV) in manufacturing processes.
- Familiarity with automation platforms (e.g., CliniMACS Prodigy, Lovo, G-Rex, Wave bioreactors).
- Experience implementing closed, automated, or high‑throughput systems.
- Experience designing and executing DOE and multivariate data analysis for cell therapy processes.
- Experience with JMP or similar statistical analysis tools.
- Experience contributing to BLA/MAA submissions or regulatory interactions.
- Knowledge of control strategy development and risk assessment tools (e.g., FMEA).
- Formal training or demonstrated application of digitalization, automation, or AI‑enabled tools in bioprocess development.
Key Competencies
- Strong experimental design and execution skills.
- Excellent cross‑functional communication and collaboration.
- Ability to operate effectively in fast‑paced, late‑stage development environments.
- Scientific curiosity, ownership mindset, and willingness to support manufacturing operations.
The annual base pay for this position ranges from $96K to $144K. Our positions offer eligibility for multiple incentives an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
# Cell Therapy
Date Posted
12-Nov-2026Closing Date
19-Nov-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
Position Summary
We are seeking a highly motivated Senior Process Engineer to support cell therapy process characterization and commercialization activities. In this role, you will play critical role in advancing late-stage cell therapy process development, process characterization, PPQ readiness, BLA‑enabling studies, and technology transfer to different manufacturing sites. This position focuses specifically on cell therapy unit operations, including T-cell enrichment, activation, transduction, washes and harvest either semi-automated or automated equipment.
The ideal candidate brings deep technical expertise, hands-on experience with cell therapy unit operations, and demonstrates success in supporting clinical and commercial readiness.
Key Responsibilities
Process development and characterization
- Design, execute, and support autologous or allogenic cell therapy process optimization and robustness studies.
- Drive implementation of closed-system operations and automation strategies to support scalability and compliance.
- Plan and execute process characterization studies (DOE, multivariate studies, scale‑down models, and scale‑up assessments) in alignment with QbD and ICH guidelines.
- Perform risk assessment, data analysis, write technical reports, and present outcome of the studies to cross‑functional teams and governance forums.
- Support development and refinement of control strategies for cell therapy processes, including raw materials, and cell therapy process parameters.
- Conduct batch record review, deviation assessment, and data trending to ensure robustness of cell therapy manufacturing processes.
- Apply AI‑enabled tools and digital analytics to accelerate data review, trend analysis, batch record evaluation, and process understanding.
PPQ, Tech Transfer & Manufacturing Readiness
- Contribute to PPQ planning, readiness, execution, and documentation for cell therapy processes.
- Support technology transfer of cell therapy processes to internal manufacturing sites including make-a-batch assessments and drafting manufacturing batch record.
- Provide on‑the‑floor technical support during scale‑up, engineering runs, PPQ batches, and commercial manufacturing campaigns (including off‑shift support when required).
- Support raw material risk assessments, comparability studies, and process risk evaluations across facilities and platforms.
Regulatory Support
- Contribute to authoring and reviewing CMC documentation, including cell therapy process descriptions, characterization summaries, PPQ protocols and reports, and control strategy elements.
- Support preparation of BLA/MAA submissions and responses to regulatory questions related to cell therapy manufacturing.
Cross‑Functional Collaboration
- Work closely with analytical sciences, quality, regulatory, and manufacturing teams to ensure end‑to‑end process alignment.
- Represent cell therapy characterization activities in technical meetings, reviews, and governance discussions.
- Support lifecycle management, post‑approval changes, and continuous improvement initiatives for cell therapy processes.
Required Qualifications
- Ph.D. in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field with 2+ years of industry experience; OR M.S. with 5+ years; OR B.S. with 7+ years of hands‑on industry experience.
- Strong technical expertise in key cell therapy unit operations (e.g., cell isolation, activation, transduction, expansion, harvest, formulation, cryopreservation).
- Demonstrated experience with GMP operations and late‑stage / commercial readiness.
- Proven ability to analyze complex datasets, develop sound recommendations, and communicate clearly across levels
- Experience with late‑stage development, process characterization, and PPQ principles for cell therapy processes.
- Demonstrated proficiency in applying AI tools and digital solutions to data analysis, documentation, and workflow automation.
- Experience working in GMP environments, including batch record execution or review, deviations, and investigations.
- Strong technical writing, data analysis, and problem‑solving skills.
Preferred Qualifications
- Experience with viral vector handling (Lentivirus, AAV) in manufacturing processes.
- Familiarity with automation platforms (e.g., CliniMACS Prodigy, Lovo, G-Rex, Wave bioreactors).
- Experience implementing closed, automated, or high‑throughput systems.
- Experience designing and executing DOE and multivariate data analysis for cell therapy processes.
- Experience with JMP or similar statistical analysis tools.
- Experience contributing to BLA/MAA submissions or regulatory interactions.
- Knowledge of control strategy development and risk assessment tools (e.g., FMEA).
- Formal training or demonstrated application of digitalization, automation, or AI‑enabled tools in bioprocess development.
Key Competencies
- Strong experimental design and execution skills.
- Excellent cross‑functional communication and collaboration.
- Ability to operate effectively in fast‑paced, late‑stage development environments.
- Scientific curiosity, ownership mindset, and willingness to support manufacturing operations.
The annual base pay for this position ranges from $96K to $144K. Our positions offer eligibility for multiple incentives an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
# Cell Therapy
Date Posted
12-Nov-2026Closing Date
19-Nov-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
See All 47 Process Engineer Jobs in Maryland
Find roles in Maryland that match your experience and apply in just a few clicks.
Find Process Engineer JobsProcess Engineer Jobs by City in Maryland
Where Maryland roles are concentrated, by current openings.
Process Engineer Job Market in Maryland
A snapshot from current Maryland openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Food & Beverage
- Technology & Software
What Maryland Employers Look For
The qualifications that appear most often in process engineer jobs across Maryland.
- Bachelor's degree in chemical, industrial, or mechanical engineering from an accredited program
- Experience with GMP or FDA-regulated manufacturing environments in biotech or pharma
- Proficiency with process simulation tools such as Aspen or similar platforms
- Ability to develop and execute process validation protocols and equipment qualification studies
- Familiarity with Lean, Six Sigma, or continuous improvement methodologies in a production setting
- Strong technical writing skills for SOPs, batch records, and deviation investigations
Process Engineer Jobs in Maryland: Frequently Asked Questions
How do you become a process engineer in Maryland?
Most process engineer positions in Maryland require a bachelor's degree in chemical, mechanical, or industrial engineering from an ABET-accredited program. While Maryland does not mandate a state-issued license for most private-sector process engineering roles, candidates pursuing licensed professional engineer status can apply through the Maryland State Board of Professional Engineers, which accepts both the FE and PE exams. Life sciences employers in particular prioritize GMP training and industry certifications alongside the core degree.
Which companies hire process engineers in Maryland?
Maryland process engineer roles are posted by Peraton, Coty, and Saft and others right now, based on current listings on Migrate Mate as of November 2026. Maryland's concentration of defense contractors, pharmaceutical manufacturers, and biotech firms means openings appear consistently across both the Baltimore metro and the Montgomery County life sciences corridor.
Which Maryland cities have the most process engineer jobs?
Fort Meade, Rockville, and Salisbury account for the largest share of process engineer openings in Maryland. Baltimore anchors the market through its refining, food processing, and hospital supply chain operations, while Rockville and Gaithersburg draw volume from the dense cluster of biopharmaceutical and federal contractor campuses along the Interstate 270 technology corridor.
Are there remote process engineer jobs in Maryland?
Yes, but they're rare. Process engineering is largely hands-on work tied to physical equipment, production lines, and regulated manufacturing floors, so most roles require an on-site presence. About 63% of process engineer openings tied to Maryland are remote or hybrid as of November 2026, and those positions tend to focus on process design, documentation review, or validation planning rather than direct floor support.
How can I get hired as a process engineer in Maryland with little or no experience?
The most realistic entry path is a co-op or internship with one of Maryland's large biotech or defense manufacturers, which often convert to full-time roles. Companies operating regulated manufacturing sites in the Baltimore-Washington corridor frequently hire process engineering associates or validation engineers as entry-level titles. Earning a Lean Six Sigma White or Yellow Belt certificate and building familiarity with GMP documentation strengthens a new-graduate application considerably. Community college continuing education programs in the region also offer GMP and bioprocess fundamentals that Maryland life sciences employers recognize.
Where can I find and apply to process engineer jobs in Maryland?
You can find and apply to process engineer jobs in Maryland on Migrate Mate, which lists current Maryland openings. Search the listings to find roles that match your background and apply directly to the ones that fit your experience and location preferences.
See All 47 Process Engineer Jobs in Maryland
Find roles in Maryland that match your experience and apply in just a few clicks.
Find Process Engineer Jobs