Registered Nurse Jobs in San Antonio, TX

Registered Nurse jobs in San Antonio are in high demand, concentrated in the South Texas Medical Center corridor, downtown, and the Stone Oak area across hospital systems, long-term care, and outpatient clinics. Employers hiring right now include Methodist Healthcare System, CHRISTUS Health, and Optum. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles286+
Top employerMethodist Healthcare System
Work type86% On-site
Top credentialManaged Registered Nurses (RNs)
Companies hiring10

Showing 5 of 286+ Registered Nurse jobs

Registered Nurse (Risk Manager)
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Added 1d ago
Registered Nurse (Risk Manager)
US Department of Veterans Affairs
San Antonio, Texas
Clinical Support
Healthcare Administration
Human Resources
Nursing
$86k - $174k/yr
Hybrid
Bachelor of Science
10,000+

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Registered Nurse - Post Anesthesia Care Unit (PACU)
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Added 1d ago
Registered Nurse - Post Anesthesia Care Unit (PACU)
US Department of Veterans Affairs
San Antonio, Texas
Clinical Support
Healthcare Administration
Human Resources
Nursing
$86k - $174k/yr
On-Site
Doctoral degree
10,000+

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Registered Nurse Shift Supervisor (RN) - SDSC
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Added 2d ago
Registered Nurse Shift Supervisor (RN) - SDSC
Tenet Healthcare
San Antonio, Texas
Business Operations
Human Resources
Project Management
Managed Registered Nurses (RNs)
10,000+

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Clinical Nurse Coordinator Emergency Department RN
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Added 3d ago
Clinical Nurse Coordinator Emergency Department RN
Methodist Healthcare System
San Antonio, Texas
Customer Service
Healthcare Administration
Human Resources
5,001-10,000

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Clinical Nurse Coordinator Emergency Room RN
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Added 3d ago
Clinical Nurse Coordinator Emergency Room RN
Methodist Healthcare System
San Antonio, Texas
Customer Service
Healthcare Administration
Human Resources
5,001-10,000

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See All 286+ Registered Nurse Jobs in San Antonio

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Registered Nurse Job Market in San Antonio

Who's Hiring

  • Methodist Healthcare System99
  • CHRISTUS Health62
  • Optum25
  • US Department of Veterans Affairs25
  • HCA Healthcare12

Top Industries Hiring

  • Healthcare & Medical Services

Registered Nurse Jobs in San Antonio: Frequently Asked Questions

How do I get a registered nurse job in San Antonio?

San Antonio's strongest hiring comes from its large hospital systems clustered in the South Texas Medical Center, military-affiliated medical facilities like Brooke Army Medical Center, and a growing network of urgent care and outpatient clinics across the North Side and Stone Oak. Candidates with ICU, emergency, or med-surg experience move fastest here. Bilingual Spanish skills are a genuine edge in a city where a large share of patients prefer Spanish.

Which companies hire registered nurses in San Antonio?

Employers hiring registered nurses in San Antonio right now include Methodist Healthcare System, CHRISTUS Health, and Optum, based on current listings on Migrate Mate as of October 2026. San Antonio's market is anchored by large health systems, federal military hospitals, and a growing number of specialty and rehabilitation facilities.

Are there remote registered nurse jobs in San Antonio?

Yes, though remote work is uncommon for most registered nurse roles given the hands-on nature of direct patient care. About 14% of registered nurse openings tied to San Antonio are remote or hybrid as of October 2026. The roles most likely to offer remote flexibility in San Antonio are case management, utilization review, and telehealth triage positions.

How can I get a registered nurse job in San Antonio with little or no experience?

The most realistic entry path in San Antonio is through a new-graduate residency program, which several of the city's major hospital systems offer specifically to bridge new nurses into clinical practice. Community hospitals and long-term care facilities in areas like the West Side and Southeast San Antonio also tend to be more open to new graduates. Starting in a medical-surgical or telemetry unit and adding bilingual Spanish communication to your application strengthens your candidacy locally.

Which industries hire the most registered nurses in San Antonio?

The sectors hiring the most registered nurses in San Antonio are Healthcare & Medical Services, based on current listings on Migrate Mate as of October 2026. San Antonio's large military population, substantial retiree community, and the concentration of specialty hospitals in the Medical Center district sustain consistent demand across those sectors.

See All 286+ Registered Nurse Jobs in San Antonio

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