Senior Level Regulatory Affairs Specialist Jobs
Senior level regulatory affairs specialist jobs place experienced professionals in charge of submission strategy, cross-functional program leadership, and the regulatory outcomes their organizations depend on. Roles are concentrated in Biotechnology & Pharmaceuticals, Medical Devices, and Science & Research, with 34% offering remote or hybrid arrangements and employers like Revolution Medicines, Revolution Medicines, and Insmed Incorporated hiring at this level now.
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Responsibilities:
Regulatory Affairs Liaison: Communication with Regulators and Bank Management
- Serve as the primary liaison with regulatory agencies and the Bank during periodic examinations and BAU or ad hoc inquiries; facilitate prompt review and approval of submissions and commitment closures
- Oversee the bank examination process for exams and enhanced continuous monitoring reviews conducted by the different U.S. regulatory authorities
- Lead in maintaining fluid and regular communications between the Bank and its regulators
- Convey regulators’ inquiry/advice/comments/instruction/concerns to relevant parties and drive a resolution to address those in a timely manner
- Support key stakeholders in the writing of regulatory responses ensuring comprehensiveness and consistency across lines of business
- Manage escalations related to regulatory matters and/or deliverables, and provide support to ensure proper awareness and communication to applicable stakeholders including the regulators and Executive Management as applicable
- Ensure standards are maintained and followed related to the Bank’s regulatory interactions, including exam management, regulatory meeting, request for information and other ad hoc communications
- Drive and Execute quality reviews of all regulatory submissions to ensure deliverables meet strict deadlines and fulfil regulatory and quality standards; leverage knowledge of U.S. Banking regulations and compliance rules
- Oversee all facets of compliance-related regulatory exams, as well as additional exams covering other Independent Risk Management (IRM) functions, such as Operational Risk Management, etc., as requested by CRO; manage exam requests, meeting preparation and presentation, exam logistics, and communication of exam deadlines and updates to relevant parties, and Senior and Executive Management; and ensure efficient, effective and accurate communication between regulators and the Bank.
- Oversee the documentation and maintenance of comprehensive records of communications and regulatory affairs in line with both the Bank’s policies/standards and regulatory expectations
- Review minutes for regulatory meetings; consider internal stakeholder feedback; maintain RAO records of such
- Maintain and communicate the regulatory exam schedule, including exam results and documentation (SL) and key metrics related to RAO functions
- Establish and maintain RAO Procedure and relevant processes; facilitate procedure approvals and relevant training, as needed
- Periodically review and update the RAO Procedure, and conduct ad-hoc amendment per regulatory requirement or instruction from Management
- Develop and drive other regulatory affairs processes, as needed
- Oversee coordination and review of regulatory-related information and status updates for periodic reporting to Management and committees
- Review and assess items to be submitted for remediation validation and evaluation against stated regulatory expectations
- Review supporting documents for remediation to confirm regulatory MRAs/MRIAs are addressed
- Provide guidance and support in the development of remediation documentation and supporting information
- Monitor and track corrective actions regarding Regulatory Enforcement Action and MRA remediation plan progress; facilitate the preparation and reporting of overall remediation status of open issues to the management team; manage related communication with the regulators on ongoing and timely basis
- Organize and participate in internal meetings with stakeholders and management to discuss progress in corrective actions; and Report to Management with most updated information regarding regulatory affairs
- Other tasks or projects assigned by the Supervisor, including ad hoc regulatory updates or communications, as requested
- Bachelor’s degree required; advanced degree (i.e., MBA, JD, etc.) preferred.
- Minimum 10 years of work experience in banking, preferrably in a risk management and/or compliance-related function; prefer experience managing regulatory affairs, managing teams, and/or prior experience working at a regulatory agency. Or combination of 5 years exerience in banking and 5 years managing regulatory affairs, and/or prior experience at a regulatory agency. Understanding of bank processes, risks, controls, and overall governance framework.
- Experience in managing high-priority, cross-functional projects involving multiple stakeholders, and/or experience related to regulatory issue remediation a plus.
- Experience with committee and senior management-level reporting; development and review of policies/procedures.
- Strong knowledge of regulatory environment; knowledge of BSA/AML and Sanctions Compliance preferred.
- Excellent verbal and written communication skills
- Solid analytical and computer skills (Microsoft Office, with a focus on Excel/pivot tables) and detail-oriented.
- Strong relationship management/leadership skills; ability to work well under high-pressure situations and use negotiation/influencing skills to reach positive conclusions.
- Task oriented with sound time management skills; ability to manage and deliver against multiple priorities to meet critical deadlines.
- Strong team player mindset and effective collaborator.
- Sound problem-solving skills, able to drive solutions; possesses independent judgement and discernment.
- Strong knowledge of industry best practices, regulations, and industry developments.
- CAMS or other relevant certification preferred.
Actual salary is commensurate with candidate’s relevant years of experience, skillset, education and other qualifications.
: USD $110,000.00 - USD $230,000.00 /Yr.
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Find JobsSenior Level Regulatory Affairs Specialist Job Market
Who's Hiring
- Revolution Medicines25

- Insmed Incorporated5
- Azurity Pharmaceuticals4

- Abbott3
Top Industries Hiring
- Biotechnology & Pharmaceuticals99
- Medical Devices14
- Science & Research10
- Healthcare & Medical Services10
- Technology & Software8
Senior Level Regulatory Affairs Specialist Jobs: Frequently Asked Questions
How do I get a senior level regulatory affairs specialist job?
Employers hiring at this level look for professionals who have owned regulatory submissions end-to-end, navigated agency interactions independently, and mentored junior staff. A strong candidate brings demonstrated expertise in a specific product category or regulatory pathway, a history of cross-functional project leadership, and the ability to translate complex regulatory requirements into actionable strategy for development and commercial teams.
Which companies hire senior level regulatory affairs specialists?
Companies hiring senior level regulatory affairs specialists right now include Revolution Medicines, Revolution Medicines, and Insmed Incorporated, based on current listings on Migrate Mate as of July 2026. Hiring at this level covers large pharmaceutical and medical device manufacturers, mid-size biotech companies advancing products through approval, and contract regulatory organizations supporting multiple clients.
Are there remote senior level regulatory affairs specialist jobs?
Yes, though availability varies by employer and submission workload. About 34% of senior level regulatory affairs specialist openings are remote or hybrid as of July 2026, reflecting the document-intensive nature of the work. Roles tied to active agency meetings, site audits, or cross-site team leadership tend to require more on-site presence.
What makes a regulatory affairs specialist role senior level?
Senior level roles are defined by ownership rather than execution under supervision. A senior regulatory affairs specialist sets the submission strategy, makes independent decisions on regulatory pathways, represents the organization in agency correspondence, and is accountable for project timelines and outcomes. These roles also typically involve mentoring associates and coordinating across clinical, quality, and commercial functions.
Which industries hire the most senior level regulatory affairs specialists?
Senior Level regulatory affairs specialist roles concentrate in Biotechnology & Pharmaceuticals, Medical Devices, and Science & Research, based on current listings on Migrate Mate as of July 2026. These sectors drive hiring at this level because they operate under strict product approval requirements, face ongoing post-market compliance obligations, and need experienced professionals who can manage regulatory strategy independently.