Entry Level Safety Manager Jobs
New grad safety manager jobs open doors for recent graduates and entry level candidates with zero to two years of experience, where a strong internship background or hands-on safety coursework can matter more than a long resume. Most openings are on-site roles across Construction & Real Estate, Technology & Software, and Retail, with employers like TikTok, Chewy, and EMCOR hiring at this level now.
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Job Description
GENERAL POSITION SUMMARY
The Global Patient Safety (GPS) Pharmacovigilance Science (PVSci) Manager leads assigned activities related to cross-functional safety data monitoring, assessment, and aggregate reporting to regulatory agencies, and support signal and risk management activities.
KEY RESPONSIBILITIES
- Leads PVSci activities for assigned Vertex product, including coordinating review of emerging safety data and ensuring timely identification and communication of any potential safety issues
- Prepares aggregate safety report content, including risk management plans and responses to regulatory authority requests
- Conducts signal detection/tracking and other assessments/risk management activities
- Provides project management support for PVSci deliverables by establishing and managing timelines, content planning and tracking, and coordinating activities across multiple GPS functions (e.g., safety database report requests)
- Develops meeting materials to enable safety discussions within GPS forums (Aggregate Clinical Safety Data Review, Signal Management Team, and Disease Area Safety Team) and other cross-functional forums (e.g., data monitoring committee meetings, key results memos)
- Supports development of safety content according to program strategy and timelines (e.g., clinical study reports, drug authorization applications)
- Supports GPS Epidemiology-led study documentation
- Liaises with Regulatory Affairs and other functions to coordinate submission of aggregate safety reports
GENERAL RESPONSIBILITIES AND REQUIRED SKILLS
- Communicates clearly and proactively with cross-functional teams and stakeholders
- Demonstrates independence in managing assigned safety deliverables and timelines
- Applies strong organizational and project management skills to coordinate multiple priorities and multi-task effectively
- Analyzes, interprets, and summarizes data with guidance
- Demonstrates firm comprehension of established procedures and may identify opportunities for improvement
- Applies understanding of industry practices for drug development and pharmacovigilance
- Fluent in use of electronic systems and rapidly adopts new technology to support documentation and reporting
- Demonstrates a commitment to ongoing learning and professional development
- Seeks feedback and incorporates it to enhance deliverables and processes
EDUCATION AND EXPERIENCE
- Advanced healthcare degree (preferred) or equivalent professional experience Minimum of 2 years pharmacovigilance or relevant experience, with data analysis and medical/scientific writing; preference for aggregate/periodic safety report preparation
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$120,800 - $181,200Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Remote-EligibleFlex Eligibility Status:
In this Remote-Eligible role, you can choose to be designated as:
1. Remote : work remotely five days per week and come into the office on occasion – you’re always welcome on-site; or select
2. Hybrid : work remotely up to two days per week; or select
3. On-Site : work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Remote
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
Job Description
GENERAL POSITION SUMMARY
The Global Patient Safety (GPS) Pharmacovigilance Science (PVSci) Manager leads assigned activities related to cross-functional safety data monitoring, assessment, and aggregate reporting to regulatory agencies, and support signal and risk management activities.
KEY RESPONSIBILITIES
- Leads PVSci activities for assigned Vertex product, including coordinating review of emerging safety data and ensuring timely identification and communication of any potential safety issues
- Prepares aggregate safety report content, including risk management plans and responses to regulatory authority requests
- Conducts signal detection/tracking and other assessments/risk management activities
- Provides project management support for PVSci deliverables by establishing and managing timelines, content planning and tracking, and coordinating activities across multiple GPS functions (e.g., safety database report requests)
- Develops meeting materials to enable safety discussions within GPS forums (Aggregate Clinical Safety Data Review, Signal Management Team, and Disease Area Safety Team) and other cross-functional forums (e.g., data monitoring committee meetings, key results memos)
- Supports development of safety content according to program strategy and timelines (e.g., clinical study reports, drug authorization applications)
- Supports GPS Epidemiology-led study documentation
- Liaises with Regulatory Affairs and other functions to coordinate submission of aggregate safety reports
GENERAL RESPONSIBILITIES AND REQUIRED SKILLS
- Communicates clearly and proactively with cross-functional teams and stakeholders
- Demonstrates independence in managing assigned safety deliverables and timelines
- Applies strong organizational and project management skills to coordinate multiple priorities and multi-task effectively
- Analyzes, interprets, and summarizes data with guidance
- Demonstrates firm comprehension of established procedures and may identify opportunities for improvement
- Applies understanding of industry practices for drug development and pharmacovigilance
- Fluent in use of electronic systems and rapidly adopts new technology to support documentation and reporting
- Demonstrates a commitment to ongoing learning and professional development
- Seeks feedback and incorporates it to enhance deliverables and processes
EDUCATION AND EXPERIENCE
- Advanced healthcare degree (preferred) or equivalent professional experience Minimum of 2 years pharmacovigilance or relevant experience, with data analysis and medical/scientific writing; preference for aggregate/periodic safety report preparation
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$120,800 - $181,200Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Remote-EligibleFlex Eligibility Status:
In this Remote-Eligible role, you can choose to be designated as:
1. Remote : work remotely five days per week and come into the office on occasion – you’re always welcome on-site; or select
2. Hybrid : work remotely up to two days per week; or select
3. On-Site : work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Remote
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
See All 34 Entry Level Safety Manager Jobs
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Who's Hiring
Top Industries Hiring
- Construction & Real Estate
- Technology & Software
- Retail
- Healthcare & Medical Services
- Education
Entry Level Safety Manager Jobs: Frequently Asked Questions
How do I get an entry level safety manager job?
Start by earning a relevant degree in occupational health, environmental science, or a related field, and pursue certifications like OSHA 10 or OSHA 30 to signal baseline competency. Internship experience in a safety role carries significant weight at this level. Tailoring your resume to highlight any hazard assessments, incident reporting, or compliance work, even from coursework or volunteer settings, gives you a real edge over candidates with generic backgrounds.
Which companies hire entry level safety managers?
Companies hiring entry level safety managers right now include TikTok, Chewy, and EMCOR, based on current listings on Migrate Mate as of September 2026. Both large industrial employers and mid-size contractors tend to hire at this level, especially those with active worksites that require dedicated safety oversight and compliance support.
Are there remote entry level safety manager jobs?
Yes, though on-site roles remain more common given the hands-on nature of safety work. About 10% of entry level safety manager openings are remote or hybrid as of September 2026, typically in roles focused on safety training coordination, compliance documentation, or program administration rather than direct field supervision.
Are these new grad safety manager jobs?
Yes, many of these listings are new grad and junior roles that explicitly welcome recent graduates and candidates with little to no professional experience. A new grad-friendly posting typically accepts zero to two years of experience, counts internships or co-ops toward requirements, and values a safety-focused degree or relevant certifications over an extensive work history.
Which industries hire the most entry level safety managers?
Entry Level safety manager roles concentrate in Construction & Real Estate, Technology & Software, and Retail, based on current listings on Migrate Mate as of September 2026. These sectors tend to drive hiring at this level because their operational environments, active construction sites, manufacturing floors, and logistics facilities, require consistent on-the-ground safety presence and compliance oversight.