Senior Bioinformatics Scientist Jobs

Senior Bioinformatics Scientist jobs are open across pharmaceuticals, genomics, biotech, and academic research, from mid-level to principal, with specializations in computational genomics, structural bioinformatics, and multi-omics data analysis. Find a role that fits from the openings below and apply directly.

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Overview

Open roles54
Top stateCalifornia
Top employerThermo Fisher Scientific
Top citySouth San Francisco, CA
Work type54% On-site
Top industryScience

Showing 5 of 54+ Senior Bioinformatics Scientist jobs

Battelle
Biologist/ Bioinformatics Scientist
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Battelle
Added 3d ago
Biologist/ Bioinformatics Scientist
Battelle
Fort Belvoir, Virginia
Customer Support
IT Support
Technical Program Management
$90k - $120k/yr
Hybrid
Master's degree in epidemiology
1,001-5,000

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St. Jude Children's Research Hospital
Bioinformatics Research Scientist
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St. Jude Children's Research Hospital
Added 1w ago
Bioinformatics Research Scientist
St. Jude Children's Research Hospital
Memphis, Tennessee
Laboratory Research
Biotech & Life Sciences
Data Science & Analytics
Data Science
Data Analytics
$155k/yr
On-Site
Bachelor's

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St. Jude Children's Research Hospital
Bioinformatics Research Scientist - Center of Excellence for Pediatric Immuno-Oncology
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St. Jude Children's Research Hospital
Added 1w ago
Bioinformatics Research Scientist - Center of Excellence for Pediatric Immuno-Oncology
St. Jude Children's Research Hospital
Memphis, Tennessee
Biotech & Life Sciences
Clinical Trials
Research & Academia
$86k - $155k/yr
Bachelor's degree in statistics
5,001-10,000

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Veritas Management Group, Inc.
Bioinformatics Scientist
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Veritas Management Group, Inc.
Added 1w ago
Bioinformatics Scientist
Veritas Management Group, Inc.
Research Triangle Park, North Carolina
Biotech & Life Sciences
Data Science
Research & Academia
Master's degree in molecular biology

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ChromoLogic LLC
Senior Scientist, Bioinformatics
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ChromoLogic LLC
Added 1w ago
Senior Scientist, Bioinformatics
ChromoLogic LLC
Monrovia, California
Biotech & Life Sciences
Environmental & Physical Sciences
Laboratory Research
Research & Academia
Doctoral degree in statistics
11-50

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Senior Bioinformatics Scientist Job Market

Who's Hiring

Thermo Fisher Scientific
Thermo Fisher Scientific7 open roles
GAP Solutions
GAP Solutions3 open roles
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital3 open roles

Top Industries Hiring

  • Science & Research
  • Biotechnology & Pharmaceuticals
  • Consulting & Professional Services
  • Healthcare & Medical Services
  • Education

What Employers Look For

The qualifications that appear most often in senior bioinformatics scientist jobs.

  • PhD in bioinformatics, computational biology, genomics, or a closely related field
  • Proficiency in Python and R for statistical analysis and pipeline development
  • Experience with next-generation sequencing data analysis including RNA-seq, WGS, or scRNA-seq
  • Hands-on use of workflow management systems such as Snakemake, Nextflow, or WDL
  • Familiarity with cloud computing environments including AWS, Google Cloud, or Microsoft Azure
  • Strong record of peer-reviewed publication or contributions to open-source bioinformatics tools

Tips for Your Senior Bioinformatics Scientist Job Search

Tailor your resume to pipeline specifics

Generic bioinformatics resumes lose reviewers fast. For each application, name the exact pipelines you built or maintained, the genome assemblers or alignment tools you used, and the scale of datasets you processed. Quantify compute time saved or variant calls improved.

Apply early to roles that fit

Migrate Mate lists senior bioinformatics scientist openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Highlight reproducibility and documentation habits

Senior-level hiring panels care deeply about whether your analyses can be reproduced by the next scientist. Call out your use of workflow managers like Snakemake or Nextflow, containerization with Docker or Singularity, and version-controlled notebooks in your resume and cover letter.

Distinguish wet-lab familiarity from pure computation

Many senior roles sit at the interface of experimental and computational work. If you can interpret a sequencing QC report, design an experiment alongside bench scientists, or translate biological questions into algorithmic tasks, say so explicitly. Panels often screen for this bridge.

Prepare a technical take-home or code sample

Most senior bioinformatics scientist interviews include a coding or analysis exercise. Before your first screen, clean up a public GitHub repository or Jupyter notebook that demonstrates your end-to-end thinking on a real dataset, so you can share it on short notice.

Negotiate scope before discussing compensation

In senior bioinformatics roles, reporting structure, compute budget, and collaboration access vary enormously and affect your day-to-day output. Clarify what resources and autonomy the role actually carries before the offer stage so you negotiate from a clear picture of the position.

Senior Bioinformatics Scientist Jobs: Frequently Asked Questions

Which companies are hiring the most senior bioinformatics scientists?

The companies hiring the most senior bioinformatics scientists right now include Thermo Fisher Scientific, GAP Solutions, and St. Jude Children's Research Hospital, with the largest share of openings in California, Maryland, and New York, based on current listings on Migrate Mate as of August 2026. Pharmaceutical companies, genomics platforms, and large academic medical centers consistently drive the highest volume of postings.

How many senior bioinformatics scientist jobs are remote?

About 46% of senior bioinformatics scientist openings are fully remote or hybrid as of August 2026, making it one of the more flexible roles in the life sciences. Sub-specialties focused on computational pipeline development, machine learning model building, and data engineering tend to appear as remote most often, while roles tied to wet-lab collaboration or clinical data governance are more commonly on-site.

How do you become a senior bioinformatics scientist?

Most senior bioinformatics scientists start with a PhD in computational biology, bioinformatics, or genomics, followed by a postdoctoral fellowship or industry research role where they lead independent analyses. From there, building a portfolio of end-to-end pipeline work, contributing to publications, and demonstrating cross-functional collaboration with bench scientists positions candidates for senior individual-contributor or team-lead roles.

Can you get hired as a senior bioinformatics scientist without extensive experience?

A strong PhD plus postdoctoral or industry research experience is typically required for senior-level roles, but candidates coming from adjacent fields like computational chemistry, machine learning, or clinical data science can compete by demonstrating direct bioinformatics output. Open-source contributions, a clean public code portfolio, and domain-specific publications can offset gaps in formal job title history when applying to growth-stage biotech teams.

What does the senior bioinformatics scientist interview process look like?

The process typically starts with a recruiter screen, followed by a technical phone interview covering your pipeline architecture, tool choices, and statistical reasoning. A take-home analysis exercise or live coding session usually comes next, where you work through a real or simulated dataset. Final rounds involve presentations to the science team and conversations with cross-functional partners such as biologists, software engineers, or clinical researchers.

Where can I find and apply to senior bioinformatics scientist jobs?

You can find and apply to senior bioinformatics scientist jobs on Migrate Mate, which lists current openings from across the United States. Search the listings, find roles that match your background and research interests, and apply directly to each one. No intermediaries, no gatekeeping, just a straightforward path from opening to application.

See All 54 Senior Bioinformatics Scientist Jobs

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