Senior Bioinformatics Scientist Jobs
Senior Bioinformatics Scientist jobs are open across pharmaceuticals, genomics, biotech, and academic research, from mid-level to principal, with specializations in computational genomics, structural bioinformatics, and multi-omics data analysis. Find a role that fits from the openings below and apply directly.
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Battelle delivers when others can’t. We conduct research and development, manage national laboratories, design and manufacture products and deliver critical services for our clients—whether they are a multi-national corporation, a small start-up or a government agency.
We recognize and appreciate the value and contributions of individuals from a wide range of backgrounds and experiences and welcome all qualified individuals to apply.
Job Summary
We are currently seeking a Biologist / Bioinformatics Scientist. This position is a full-time opportunity located in Fort Belvoir, VA.
This role supports the Defense Threat Reduction Agency's (DTRA) Technical Reachback Division, which provides round-the-clock, dedicated, and independent CBRNE technical and analytical decision support. The selected candidate will bring subject matter expertise in bioinformatics, epidemiology, and/or microbiology to assist government agencies, Combatant Commands, and first responders with critical CBRNE planning, operations, and post-event analyses.
The position requires shift work and offers the opportunity to contribute to high-impact national security missions through modeling, simulation, and scientific advisory support.
Responsibilities
As a Biologist / Bioinformatics Scientist, the selected individual will provide subject matter expertise and modeling support to the DTRA Technical Reachback biology team across a range of high-priority national security missions. Responsibilities may include:
- Providing CBRNE biological decision support and technical reachback capabilities to Combatant Commands (COCOMs), the Office of the Secretary of Defense (OSD), Joint Staff (JS), the Intelligence Community (IC), first responders, and federal, state, and local government organizations in accordance with DoD directives
- Developing, integrating, testing, verifying, validating, and applying CBRNE software and scenario models based on experimental results and theoretical and computational methods
- Presenting modeling results and decision support materials to internal and external customers through written reports and oral presentations
- Providing subject matter expertise (SME) in bioinformatics, epidemiology, and/or microbiology to implement and sustain functional capabilities within DTRA Reachback
- Reviewing current research across diverse subject areas to assess relevance and applicability to ongoing projects
- Evaluating new experimental data for quality and relevance; providing biomedical defense SME in hazard prediction modeling involving CBRNE phenomena
- Working closely with scientists and engineers to define modeling objectives and obtain, verify, and validate required model inputs and outputs
- Attending technical and programmatic meetings to coordinate responses from the scientific community and review assembled materials for accuracy, consistency, and completeness
- Reviewing the technical work of other team members to ensure quality and rigor
- Shift work is required
Key Qualifications
- Master's or PhD degree in bioinformatics, epidemiology, and/or microbiology with 1–3 years of relevant experience
- Subject matter expertise in at least one of the following: bioinformatics, epidemiology, or microbiology, with application to CBRNE or biomedical defense contexts
- Strong oral and written communication skill
- \s, including technical presentation capabilities
- Proficiency in Microsoft Office and graphic visualization tools
- Collaborative, team-oriented mindset with the ability to work across scientific and operational communities
- Ability to travel up to 10% domestically, with potential for international travel
- Must be a US citizen. Must possess or have the ability to obtain and maintain a DoD Top Secret/SCI security clearance.
Preferred Qualifications
- Current DoD Top Secret/SCI clearance
- Experience combating WMD threats through modeling, simulation, and/or testing
- Working knowledge of ArcGIS tools in an operational environment
- Experience with public health threats such as COVID-19, Ebola, pandemic influenza, emerging infectious agents, and biological warfare agents
- Prior experience working with Department of Defense organizations on WMD-related issues, or with agencies such as HHS, CDC, or similar federal entities
Compensation Data
Battelle is committed to fair and equitable compensation practices. The salary range for this role is $90,000 – $120,000 per year, in addition to our comprehensive benefits package. A candidate's salary is determined by various factors, including but not limited to education, relevant work experience, skills, and certifications. Salary ranges may vary based on geographic location and market conditions.
Benefits: Live an Extraordinary Life
We care about your well-being, not just on the job. Battelle offers comprehensive and competitive benefits to help you live your best life.
- Balance life through a compressed work schedule: Most of our team follows a flexible, compressed work schedule that allows for every other Friday off—giving you a dedicated day to accomplish things in your personal life without using vacation time.
- Enjoy enhanced work flexibility, including a hybrid arrangement: You have options for where and when you work. Our Together with Flexibility model allows you to work 60% in-office and 40% remote, with Monday and Tuesday as common in-office days, dependent on team and position needs.
- Take time to recharge: You get paid time off to support work-life balance and keep motivated.
- Prioritize wellness: Stay healthy with medical, dental, and vision coverage with wellness incentives and benefits plus a variety of optional supplemental benefits.
- Better together: Coverage for partners, gender-affirming care and health support, and family formation support.
- Build your financial future: Build financial stability with an industry-leading 401(k) retirement savings plan. For most employees, we put in 5 percent whether you contribute or not, and match your contributions on top of that.
- Advance your education: Tuition assistance is available to pursue higher education.
A Work Environment Where You Succeed
For brilliant minds in science, technology, engineering and business operations, Battelle is the place to do the greatest good by solving humanity’s most pressing challenges and creating a safer, healthier and more secure world.
You will have the opportunity to thrive in a culture that inspires you to:
- Apply your talent to challenging and meaningful projects
- Receive select funding to pursue ideas in scientific and technological discovery
- Partner with world-class experts in a collaborative environment
- Nurture and develop the next generation of scientific leaders
- Give back to and improve our communities
Vaccinations & Safety Protocols
Battelle may require employees, based on job duties, work location, and/or its clients’ requirements to follow certain safety protocols and to be vaccinated against a variety of viruses, bacteria, and diseases as a condition of employment and continued employment and to provide documentation that they are fully vaccinated. If applicable, Battelle will provide reasonable accommodations based on a qualified disability or medical condition through the Americans with Disabilities Act or the Rehabilitation Act or for a sincerely held religious belief under Title VII of the Civil Rights Act of 1964 (and related state laws).
Battelle is an equal opportunity employer. We provide employment and opportunities for advancement, compensation, training, and growth according to individual merit, without regard to race, color, religion, sex (including pregnancy), national origin, sexual orientation, gender identity or expression, marital status, age, genetic information, disability, veteran-status veteran or military status, or any other characteristic protected under applicable Federal, state, or local law. Our goal is for each staff member to have the opportunity to grow to the limits of their abilities and to achieve personal and organizational objectives. We will support positive programs for equal treatment of all staff and full utilization of all qualified employees at all levels within Battelle.
The above statements are intended to describe the nature and level of work being performed by people assigned to this job. They are not intended to be an exhaustive list of all responsibilities, activities and skills required of staff members. No statement herein is intended to imply any authorities to commit Battelle unless special written permission is granted by Battelle's Legal Department.
For more information about our other openings, please visit www.battelle.org/careers
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Who's Hiring



Top Industries Hiring
- Science & Research
- Biotechnology & Pharmaceuticals
- Consulting & Professional Services
- Healthcare & Medical Services
- Education
What Employers Look For
The qualifications that appear most often in senior bioinformatics scientist jobs.
- PhD in bioinformatics, computational biology, genomics, or a closely related field
- Proficiency in Python and R for statistical analysis and pipeline development
- Experience with next-generation sequencing data analysis including RNA-seq, WGS, or scRNA-seq
- Hands-on use of workflow management systems such as Snakemake, Nextflow, or WDL
- Familiarity with cloud computing environments including AWS, Google Cloud, or Microsoft Azure
- Strong record of peer-reviewed publication or contributions to open-source bioinformatics tools
Tips for Your Senior Bioinformatics Scientist Job Search
Tailor your resume to pipeline specifics
Generic bioinformatics resumes lose reviewers fast. For each application, name the exact pipelines you built or maintained, the genome assemblers or alignment tools you used, and the scale of datasets you processed. Quantify compute time saved or variant calls improved.
Apply early to roles that fit
Migrate Mate lists senior bioinformatics scientist openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Highlight reproducibility and documentation habits
Senior-level hiring panels care deeply about whether your analyses can be reproduced by the next scientist. Call out your use of workflow managers like Snakemake or Nextflow, containerization with Docker or Singularity, and version-controlled notebooks in your resume and cover letter.
Distinguish wet-lab familiarity from pure computation
Many senior roles sit at the interface of experimental and computational work. If you can interpret a sequencing QC report, design an experiment alongside bench scientists, or translate biological questions into algorithmic tasks, say so explicitly. Panels often screen for this bridge.
Prepare a technical take-home or code sample
Most senior bioinformatics scientist interviews include a coding or analysis exercise. Before your first screen, clean up a public GitHub repository or Jupyter notebook that demonstrates your end-to-end thinking on a real dataset, so you can share it on short notice.
Negotiate scope before discussing compensation
In senior bioinformatics roles, reporting structure, compute budget, and collaboration access vary enormously and affect your day-to-day output. Clarify what resources and autonomy the role actually carries before the offer stage so you negotiate from a clear picture of the position.
Senior Bioinformatics Scientist Jobs: Frequently Asked Questions
Which companies are hiring the most senior bioinformatics scientists?
The companies hiring the most senior bioinformatics scientists right now include Thermo Fisher Scientific, GAP Solutions, and St. Jude Children's Research Hospital, with the largest share of openings in California, Maryland, and New York, based on current listings on Migrate Mate as of August 2026. Pharmaceutical companies, genomics platforms, and large academic medical centers consistently drive the highest volume of postings.
How many senior bioinformatics scientist jobs are remote?
About 46% of senior bioinformatics scientist openings are fully remote or hybrid as of August 2026, making it one of the more flexible roles in the life sciences. Sub-specialties focused on computational pipeline development, machine learning model building, and data engineering tend to appear as remote most often, while roles tied to wet-lab collaboration or clinical data governance are more commonly on-site.
How do you become a senior bioinformatics scientist?
Most senior bioinformatics scientists start with a PhD in computational biology, bioinformatics, or genomics, followed by a postdoctoral fellowship or industry research role where they lead independent analyses. From there, building a portfolio of end-to-end pipeline work, contributing to publications, and demonstrating cross-functional collaboration with bench scientists positions candidates for senior individual-contributor or team-lead roles.
Can you get hired as a senior bioinformatics scientist without extensive experience?
A strong PhD plus postdoctoral or industry research experience is typically required for senior-level roles, but candidates coming from adjacent fields like computational chemistry, machine learning, or clinical data science can compete by demonstrating direct bioinformatics output. Open-source contributions, a clean public code portfolio, and domain-specific publications can offset gaps in formal job title history when applying to growth-stage biotech teams.
What does the senior bioinformatics scientist interview process look like?
The process typically starts with a recruiter screen, followed by a technical phone interview covering your pipeline architecture, tool choices, and statistical reasoning. A take-home analysis exercise or live coding session usually comes next, where you work through a real or simulated dataset. Final rounds involve presentations to the science team and conversations with cross-functional partners such as biologists, software engineers, or clinical researchers.
Where can I find and apply to senior bioinformatics scientist jobs?
You can find and apply to senior bioinformatics scientist jobs on Migrate Mate, which lists current openings from across the United States. Search the listings, find roles that match your background and research interests, and apply directly to each one. No intermediaries, no gatekeeping, just a straightforward path from opening to application.
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