Senior Staff Engineer Jobs in North Carolina
Senior Staff Engineer jobs in North Carolina are open across Morrisville, Raleigh, and Charlotte and other North Carolina metros, with employers like Thermo Fisher Scientific, Google, and Becton, Dickinson and Company hiring at every experience level. Find a role that fits below and apply directly.
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Work Schedule
Standard (Mon-Fri)
Environmental Conditions
Office
Job Description
We are seeking an experienced HL7 Developer to design, develop, and maintain healthcare data interfaces that enable seamless interoperability between clinical systems. The ideal candidate will have strong expertise in HL7 standards, healthcare data workflows, and integration engines, ensuring accurate, secure, and compliant data exchange across systems.
Key Responsibilities
- Design, develop, and maintain HL7 interfaces (v2.x, v3, CDA, FHIR) between healthcare systems
- Build and support integrations with EHR/EMR systems (e.g., Epic, Cerner, Allscripts)
- Configure and manage integration engines (e.g., Mirth Connect, Rhapsody, Cloverleaf)
- Analyze, transform, and map healthcare data formats and message structures
- Troubleshoot interface issues, message failures, and data discrepancies
- Implement data validation, error handling, and logging mechanisms
- Ensure compliance with HIPAA and healthcare data security standards
- Collaborate with clinical, technical, and vendor teams to define integration requirements
- Support real-time and batch data exchange workflows
- Maintain documentation for interfaces, mappings, and workflows
Required Qualifications
- Bachelor’s degree in Computer Science, Health Informatics, or related field
- 10+ years of experience in healthcare IT, interface development, or systems integration
- 7+ years of hands-on experience with HL7 v2.x, HL7 FHIR, X12, or other healthcare messaging standards
- Strong knowledge of HL7 v2.x messaging standards (ADT, ORU, ORM, etc.)
- Experience with FHIR APIs and modern interoperability frameworks
- Hands-on experience with integration engines (Mirth Connect preferred)
- Proficiency in Java, JavaScript, or similar scripting languages
- Experience with XML, JSON, and RESTful APIs
- Understanding of healthcare workflows and clinical data
Preferred Qualifications
- Experience with HL7 v3, CDA/CCD documents
- Familiarity with FHIR resources and SMART on FHIR
- Knowledge of healthcare interoperability standards (HL7, DICOM, X12)
- Experience integrating with Epic, Cerner, or other major EHR systems
- Understanding of cloud platforms (AWS, Azure, GCP)
- Certification in HL7 or healthcare integration technologies
Key Skills
- HL7 message parsing and transformation
- Data mapping and interface development
- Problem-solving and debugging
- Communication with technical and non-technical stakeholders
- Attention to detail and data accuracy
See All 11 Senior Staff Engineer Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find Senior Staff Engineer JobsSenior Staff Engineer Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Senior Staff Engineer Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
- Thermo Fisher Scientific4

- Google3

- Becton, Dickinson and Company1

- Intuit1

- OneMain Financial1

Top Industries Hiring
- Consulting & Professional Services6
- Science & Research3
- Medical Devices1
- Technology & Software1
What North Carolina Employers Look For
The qualifications that appear most often in senior staff engineer jobs across North Carolina.
- 8 or more years of software engineering experience with progressive technical scope
- Deep expertise in distributed systems, large-scale infrastructure, or platform architecture
- Proven experience leading technical design reviews and cross-team engineering decisions
- Proficiency in one or more of Java, Go, Python, C++, or Scala at production scale
- Experience mentoring senior engineers and driving org-wide technical standards
- Bachelor's or master's degree in computer science, engineering, or a closely related field
Senior Staff Engineer Jobs in North Carolina: Frequently Asked Questions
How many senior staff engineer jobs are there in North Carolina?
There are 11+ senior staff engineer openings in North Carolina on Migrate Mate as of June 2026, with the most roles in Morrisville, Raleigh, and Charlotte. New positions post regularly as employers across North Carolina hire.
Which North Carolina cities have the most senior staff engineer jobs?
Morrisville, Raleigh, and Charlotte have the most senior staff engineer openings in North Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire senior staff engineers in North Carolina?
Employers hiring senior staff engineers in North Carolina include Thermo Fisher Scientific, Google, and Becton, Dickinson and Company, based on current listings on Migrate Mate as of June 2026.
Are there remote senior staff engineer jobs in North Carolina?
Yes. About 9% of senior staff engineer openings tied to North Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in North Carolina metros.
How do I apply for senior staff engineer jobs in North Carolina?
You can apply to senior staff engineer jobs in North Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred North Carolina location, then apply to each one that fits.
See All 11 Senior Staff Engineer Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
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