Vice President of Clinical Operations Jobs
Vice President of Clinical Operations jobs are open across health systems, pharmaceutical companies, CROs, and biotech firms, at levels from director-track to C-suite-adjacent, with specializations in trial operations, care delivery, and regulatory affairs. Find a role that fits below and apply directly.
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The Vice President develops the overarching operational approach across CCBHC and behavioral health service lines, including mental health, substance use/SUPR, crisis, outpatient and community-based services, care coordination, psychiatric rehabilitation, targeted case management, and peer support.
Working in close partnership with the Vice President of Clinical Services, medical leadership, and organizational functions, this role determines how clinical strategy will be operationalized across programs and locations. Program directors and operational leaders are responsible for implementing these strategies within their respective service areas.
Responsibilities:
Enterprise Clinical Operations Strategy
- Translate the organization’s clinical model and strategic priorities into enterprise operating strategies, implementation frameworks, and measurable operational objectives.
- Design scalable approaches to service delivery that support consistency across programs while allowing for program- and population-specific needs.
- Identify system-level operational barriers affecting access, capacity, client experience, workforce performance, or financial sustainability and develop strategies to address them.
- Establish operational performance expectations and provide strategic direction to directors and leaders responsible for day-to-day implementation.
Access, Capacity & Service Delivery
- Establish enterprise strategies to improve timely access to CCBHC and non-CCBHC services across the continuum of care.
- Use trends in referrals, intake, scheduling, treatment initiation, utilization, and service demand to guide capacity planning and resource allocation.
- Develop approaches to optimize clinical capacity, service availability, hours of operation, and transitions between levels of care.
- Partner with Clinical Services to ensure operational strategies support the intended model of care and continuity across service lines.
Operating Model & Implementation
- Determine the operational infrastructure required to implement clinical models across crisis, mental health, substance use/SUPR, care coordination, rehabilitation, case management, and peer support services.
- Develop enterprise frameworks for staffing models, workflows, scheduling, technology, facilities, administrative support, and implementation sequencing.
- Lead operational planning for new services, changes to the clinical model, and expansion or redesign of existing programs.
- Provide directors with clear operational strategy, performance expectations, and implementation priorities.
Workforce & Leadership Strategy
- Develop organization-wide workforce and capacity strategies aligned with service demand, clinical requirements, and organizational priorities.
- Partner with Human Resources and Clinical Services on workforce planning, recruitment, retention, leadership development, and succession strategies.
- Establish expectations for operational leadership and management accountability across programs.
- Use workforce data and organizational trends to identify systemic staffing or leadership needs requiring enterprise-level intervention.
Performance, Financial & Resource Strategy
- Establish enterprise approaches to productivity, capacity, utilization, and operational performance in partnership with Finance, Clinical Services, and executive leadership.
- Use operational and financial data to identify trends, establish priorities, guide resource allocation, and recommend system-level improvements.
- Partner with Finance to align staffing models, service demand, budgets, reimbursement, and program sustainability.
- Partner with Revenue Cycle and other functions to address systemic barriers affecting documentation completion, billing, reimbursement, and financial performance.
Integrated Care & Community Operations
- Design operational frameworks that support integration of behavioral health, substance use, primary care, and social services.
- Establish organization-wide approaches for referrals, transitions of care, information sharing, hospital follow-up, and coordination with external partners.
- Develop operational strategies for relationships with hospitals, FQHCs, healthcare providers, social service organizations, governmental entities, and collaborating organizations.
- Ensure partnership structures and workflows support the clinical model and organizational performance expectations.
Quality, Compliance & CCBHC Implementation
- Partner with Clinical Services, Quality, and Compliance to translate CCBHC, Medicaid, IDHS/SUPR, licensing, accreditation, and contractual requirements into effective operational systems.
- Develop enterprise implementation strategies in response to audits, regulatory reviews, accreditation findings, and corrective action requirements.
- Ensure operational policies, processes, and performance structures support continuous CCBHC readiness and consistent implementation across programs.
Technology, Infrastructure & Business Continuity
- Provide strategic direction for EHR workflows, reporting, scheduling, referrals, and other technology required to support service delivery.
- Assess complete facility, technology, equipment, space, and infrastructure needs in relation to the clinical model and projected service demand.
- Guide business continuity and operational preparedness strategies for service disruptions, workforce shortages, emergencies, and other significant events.
Client Experience & Operational Improvement
- Establish strategies that support accessible, responsive, welcoming, trauma-informed, and person-centered service delivery throughout the organization.
- Use client experience, grievance, access, and utilization trends to identify systemic operational issues and opportunities for improvement.
- Partner with Clinical Services when client experience or operational trends indicate a potential need to reconsider the care model or clinical approach.
Experience:
- Minimum of 10 years of progressive healthcare, behavioral health, or human services experience, including at least 5 years in senior leadership with responsibility for multiple programs, service lines, departments, or locations.
- Demonstrated experience developing and implementing enterprise operational strategies within complex behavioral health or healthcare environments.
- Experience with CCBHC, community mental health, crisis services, substance use/SUPR programs, Medicaid, and integrated care strongly preferred.
- Demonstrated experience with workforce and capacity planning, productivity, financial management, performance improvement, technology-enabled workflows, and regulatory compliance.
- Experience leading large-scale change, service expansion, operational redesign, or implementation across multidisciplinary and geographically dispersed programs preferred.
- Strong ability to analyze complex operational data, identify system-level trends, and translate strategy into scalable implementation models.
Education:
- Master’s degree in Healthcare Administration, Business Administration, Public Health, Behavioral Health Administration, Social Work, Human Services, or a related field strongly preferred.
- Bachelor’s degree with significant senior-level behavioral health operations experience may be considered.
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Find JobsVice President of Clinical Operations Job Market
Who's Hiring


Top Industries Hiring
- Insurance
- Banking & Financial Services
- Biotechnology & Pharmaceuticals
What Employers Look For
The qualifications that appear most often in vice president of clinical operations jobs.
- 10 or more years of progressive clinical operations or clinical research experience
- Proven leadership of multi-site or multi-functional clinical teams
- Deep knowledge of FDA regulations, GCP guidelines, and clinical trial protocols
- Experience with clinical trial management systems and electronic data capture platforms
- Advanced degree in life sciences, healthcare administration, or a related field
- Demonstrated ability to manage operational budgets and vendor contracts
Tips for Your Vice President of Clinical Operations Job Search
Quantify your clinical oversight impact
Hiring committees for VP-level clinical roles want to see scope, not just titles. Reframe your resume around patient volume managed, sites overseen, budget authority, and measurable outcomes like reduced adverse event rates or faster protocol implementation timelines.
Align credentials to your target sector
A VP of Clinical Operations role at a CRO reads differently from one at a health system or biotech. Tailor which certifications and regulatory frameworks you lead with: ICH-GCP and FDA 21 CFR Part 11 for trials, Joint Commission and CMS for care delivery roles.
Apply early to roles that fit
Migrate Mate lists vice president of clinical operations openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Target postings by organizational growth stage
Early-stage biotechs and health tech companies often need a VP who builds infrastructure from scratch, while mature health systems want operators who optimize existing teams. Reading the job description for phrases like 'build' versus 'scale' tells you which mode the employer is in.
Prepare a cross-functional leadership narrative
VP-level clinical operations panels typically include CMO, CFO, and legal stakeholders, not just HR. Practice articulating how you've navigated conflicts between clinical quality, compliance timelines, and budget constraints. Interviewers at this level probe for enterprise thinking, not departmental execution.
Negotiate scope before you negotiate compensation
Before accepting a VP of Clinical Operations offer, clarify reporting structure, number of direct reports, and capital allocation authority in writing. Titles vary enormously across organizations, and two roles with identical names can differ by an order of magnitude in real decision-making power.
Vice President of Clinical Operations Jobs: Frequently Asked Questions
Which companies are hiring the most vice president of clinical operationss?
The most active employers for vice president of clinical operationss right now are Beacon Health Management, BNY, and Journey, and the most openings are in Georgia, New York, and California, based on current listings on Migrate Mate as of November 2026. Activity shifts with clinical pipeline expansions and health system mergers, so checking current listings regularly gives you the most accurate picture.
How many vice president of clinical operations jobs are remote?
About 80% of vice president of clinical operations openings are fully remote or hybrid as of November 2026, with remote flexibility most common in clinical research and CRO settings where site oversight is delegated to on-the-ground monitors. Roles tied to direct care delivery or hospital operations tend to require a physical presence at the organization's primary location.
How do you become a vice president of clinical operations?
Most vice presidents of clinical operations progress through clinical coordinator, manager, and director roles over many years, building expertise in regulatory compliance, budget management, and cross-functional leadership along the way. An advanced degree in a life sciences or healthcare field strengthens candidacy, as does hands-on experience leading large-scale trials, care programs, or multi-site teams through regulatory submissions or accreditation reviews.
Can you get a vice president of clinical operations job without direct VP experience?
Yes, candidates who have served as a director of clinical operations or held a senior leadership role with equivalent scope are regularly considered for VP openings, particularly at growing companies building out their leadership layer for the first time. The clearest path is demonstrating that you've already owned the core responsibilities: team leadership, budget authority, regulatory accountability, and cross-functional stakeholder management, even if the title on your resume was one level below.
What does the vice president of clinical operations interview process look like?
The process typically starts with an HR or talent screen focused on background and leadership style, followed by a panel interview with the CMO, CFO, and sometimes the board, where you'll be expected to present your operational philosophy and a vision for the function. Many organizations also include a case-style exercise asking you to respond to a scenario involving a site shutdown, budget overrun, or regulatory finding, so preparing concrete examples from your own experience is essential before each stage.
Where can I find and apply to vice president of clinical operations jobs?
You can find and apply to vice president of clinical operations jobs on Migrate Mate, which lists current openings from across the United States in one place. Find roles that match your background and apply directly to each listing without being redirected through additional sign-up steps.
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