STEM OPT Jobs in Maryland
Maryland's concentration of federal agencies, defense contractors, and life sciences employers in the Baltimore-Washington corridor makes it one of the stronger markets for F-1 STEM OPT sponsorship. Biotechnology, cybersecurity, and federal contracting roles dominate, with major hubs in Bethesda, Rockville, Baltimore, and the I-270 tech corridor.
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Position Objective: The Bioinformatics Scientist will provide support services to the National Cancer Institute within the National Institutes of Health.
Duties and Responsibilities:
- Use existing infrastructure and optimize Exome/Targeted/RNA Sequencing Data
- Analysis pipelines for clinical sequencing projects
- Develop pipelines to integrate complex genomic data including germ line, somatic DNA mutations, RNAseq and SNP assays
- Work with staff on the production of a data compendium enumerating the frequency of variations from tumor/normal samples
- Install and maintain local version of cBIO Portal
- Upload Labs Data on cBIO Portal for easy visualization
- Work with staff to utilize NIH Biowulf computer clusters to process data streamed off the next generation sequencers (NGS); process data in a batch mode
- Perform biological sequence analysis/assembly and public genome databases
- Collect and review data; analyze and interpret data and results; provide reports based on analysis of scientific data
- Report research outcomes and make recommendations for future work
- Work with staff on data visualization to support the preparation of presentations and manuscripts for submission to scientific journals
- Bioinformatics Lab meetings, scheduling and notes writing
- Co-write manuscripts
- Develop annotation algorithms and databases with all publically available data including Annovar, 1000genomes, ExAC, MyCancerGenome, ClinSeq, ESP, ClinVar, HGMD and other databases as released
- Develop new algorithms for analysis of next generation sequencing and other genomics data
- Support implementation of publically available tools in local server environment
- Write manuals to implement tools for other users
- Teach staff to use NGS and other genomic analysis tools
- Provide advice to staff about data analysis pipelines
- Work products and documents related to using existing infrastructure and optimizing pipelines for clinical sequencing projects; develop pipelines to integrate data; work with staff on the production of a data compendium enumerating the frequency of variations from tumor/normal samples
- Work products and documents related to installing and maintaining local version of cBIO Portal; upload data on cBIO Portal; process data streamed off the NGS; process data in a batch mode
- Work products and documents related to performing biological sequence analysis/assembly; collect, review, analyze and interpret data; prepare reports; manage Bioinformatics Lab meetings; co-write manuscripts
- Work products and documents related to developing annotation algorithms and databases; develop new algorithms for analysis of next generation sequencing and other genomics data
- Work products and documents related to implementing tools in local server environment; write manuals; teach staff
Basic Qualifications:
- Master’s degree in Bioinformatics or related field of study
- Skilled in R, Next gen sequencing data analysis: Bulk RNA-Sequencing, Single Cell RNA-Sequencing, and working with large data sets
Preferred Qualifications:
- Ability to communicate effectively, orally and in writing, with non-technical and technical staff
- Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects
This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required by this position.
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
GAP Solutions provides reasonable accommodations to qualified individuals with disabilities. If you need an accommodation to apply for a job, email us at recruiting@gapsi.com. You will need to reference the requisition number of the position in which you are interested. Your message will be routed to the appropriate recruiter who will assist you. Please note, this email address is only to be used for those individuals who need an accommodation to apply for a job. Emails for any other reason or those that do not include a requisition number will not be returned.
Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by law.
This position is contingent upon contract award.
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Tips for Finding STEM OPT Jobs in Maryland
Verify your role qualifies under STEM OPT
Cross-check your job title against O*NET to confirm the Standard Occupational Classification code aligns with a STEM-designated field before accepting any offer. Maryland employers in federal contracting often post hybrid roles that blend policy and technical work, and only the technical component qualifies.
Target E-Verify enrolled employers in Maryland
STEM OPT extension requires your employer to be enrolled in E-Verify. Many smaller Maryland biotech firms and defense subcontractors are not yet enrolled, so confirm enrollment status before investing time in their interview process rather than after an offer.
Search F-1 STEM OPT jobs on Migrate Mate
Migrate Mate filters Maryland employers by their DOL Labor Condition Application filing history, so you can see which companies have actively sponsored STEM OPT workers rather than guessing from job descriptions alone. Focus your search on the Bethesda and Rockville corridors for life sciences roles.
Map your DSO filing timeline against Maryland hiring cycles
Federal agencies and contractors in Maryland often have hiring freezes tied to budget cycles, particularly around the federal fiscal year end in September. Your DSO must file your STEM OPT extension application 90 days before your OPT end date, so coordinate early if your offer lands near that window.
See all 434+ F-1 STEM OPT jobs in Maryland
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Get Access To All JobsF-1 STEM OPT Jobs in Maryland: Frequently Asked Questions
Which industries in Maryland sponsor the most F-1 STEM OPT visas?
Life sciences and biotechnology employers concentrated along the I-270 corridor in Rockville and Gaithersburg sponsor heavily, as do cybersecurity and defense technology firms near Fort Meade and Annapolis Junction. Federal contractors in the Baltimore-Washington corridor and research institutions affiliated with the National Institutes of Health in Bethesda are also consistent F-1 STEM OPT sponsors.
Which cities in Maryland have the most F-1 STEM OPT sponsorship jobs?
Bethesda and Rockville lead for life sciences and health IT roles, anchored by proximity to federal health agencies. Baltimore has a growing cluster of biotech and data analytics employers. The suburban Maryland corridor running from Silver Spring through College Park into Greenbelt concentrates federal contractor and engineering roles that routinely sponsor F-1 STEM OPT workers.
What types of roles typically qualify for F-1 STEM OPT sponsorship in Maryland?
Roles must fall under a STEM-designated Standard Occupational Classification code as defined by DHS. In Maryland, this commonly includes software engineers, data scientists, biomedical researchers, cybersecurity analysts, electrical engineers, and bioinformatics specialists. Administrative, project management, or policy-focused roles at the same employers generally do not qualify even when posted under a technical team.
How do I find F-1 STEM OPT sponsorship jobs in Maryland?
Migrate Mate lets you filter Maryland employers by their DOL filing history, showing which companies have actively filed Labor Condition Applications for STEM OPT workers rather than relying on job description language alone. Prioritize employers already enrolled in E-Verify, which is a hard STEM OPT requirement, and focus searches on Bethesda, Rockville, Baltimore, and the College Park area.
Are there any Maryland-specific considerations for F-1 STEM OPT sponsorship?
Maryland's high concentration of federal contractors means many employers require security clearance eligibility, which can complicate STEM OPT placement since clearances take time to process. Additionally, employers in Maryland's life sciences sector sometimes use contract-to-hire arrangements where the contracting agency, not the end client, must be E-Verify enrolled and sign the Form I-983 Training Plan with USCIS.