Technology OPT Jobs in Massachusetts
Massachusetts is one of the strongest states for F-1 OPT students pursuing technology careers, with a dense concentration of employers in Greater Boston, Cambridge, and the Route 128 corridor. Companies like HubSpot, Wayfair, Raytheon Technologies, and hundreds of biotech and fintech firms actively hire international students for software, data, and engineering roles.
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Get Access To All JobsCOMPANY INTRODUCTION
Triveni Bio is breaking new ground in the identification of novel disease targets – working at the convergence of human genetics, best-in-class antibody design, and precision medicine. We are pioneering a Mendelian genetics-informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory (I&I) disorders. Our lead antibody program (TRIV-509) targets kallikreins 5 and 7 (KLK5/7) to directly impact skin barrier function, inflammation, and itch – providing a meaningful and much needed potential treatment option for patients with atopic dermatitis and other barrier disorders. In all the work we do, we adhere to our core values: patient impact, bold and rigorous science, open collaboration, kindness & respect.
SUMMARY
We are seeking a motivated, detail-oriented Senior Scientist to join our Clinical Pharmacology team. In this hands-on role, you will contribute directly to data analysis, modeling, and operational tracking across our clinical-stage and pipeline programs. Working closely with cross-functional teams, you will perform non-compartmental analyses (NCA), population PK/PD modeling, help define and implement bioanalytical strategies, manage bioanalytical data, and actively participate in clinical study team meetings. This is an exciting opportunity for an early-career scientist with 2–3 years of experience looking to expand their skills in hands-on quantitative clinical pharmacology and biologic drug development. Reporting into the Exec. Director, Clinical Pharmacology, and working closely with Clinical Development, Translational Medicine, Biometrics, Regulatory Affairs, and external partners, the Senior Scientist will help generate data and insights that inform dose selection, study design, and key development decisions.
Responsibilities
- Support the development and implementation of clinical pharmacology plans for clinical development programs
- Contribute to the design of PK, PD, biomarker, immunogenicity, and exposure-response assessments in clinical studies
- Perform Non-Compartmental Analysis (NCA) using standard software (e.g., Monolix or R) to support clinical study
- Execute data assembly, dataset generation, and preliminary quantitative analyses for Population PK/PD (popPK/PD) and exposure-response modeling using R, Monolix, or equivalent platforms
- Generate high-quality graphical visualizations and summary tables of clinical PK/PD for internal study team updates
- Attend and participate in cross-functional clinical study team meetings, representing the Clinical Pharmacology function
- Collaborate with internal teams and external vendors to ensure timely execution of clinical pharmacology analyses and deliverables
- Assist in the preparation and review of clinical study protocols, statistical analysis plans, clinical study reports, and other development documents
- Support the preparation of clinical pharmacology components of regulatory submissions and health authority responses
- Contribute to model-informed drug development activities and pharmacometric analyses through collaboration with internal and external experts
- Present study results and data interpretations to project teams and functional leadership
- Maintain knowledge of current scientific, regulatory, and industry trends in clinical pharmacology and pharmacometrics
- Other duties as assigned
EXPERIENCE & QUALIFICATIONS
- Ph.D. or M.S. in Clinical Pharmacology, Pharmaceutical Sciences, Pharmacometrics, Pharmacokinetics, Biomedical Sciences, or a related scientific discipline
- 2+ years (Ph.D.) or 5+ years (M.S.) years of relevant industry experience in biotechnology, pharmaceutical, or CRO environments; postdoctoral experience may be considered
- Proficiency with R for data manipulation, statistical reporting, and data visualization. Hands-on experience or academic exposure to pharmacometric platforms such as Monolix, or NONMEM
- Experience supporting clinical development programs, preferably involving biologics, antibodies, or immunology/inflammation therapeutics
- Knowledge of PK, PD, exposure-response relationships, immunogenicity assessments, and clinical pharmacology principles
- Experience working with external CROs and bioanalytical laboratories
- Strong scientific communication and data presentation skills
- Experience contributing to regulatory documentation is preferred
- Ability to travel up to 10% as needed
The posted range reflects the current reasonable and good faith estimate of the base salary for this full-time position. Actual compensation will be based on a variety of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location and other organizational needs. This role also offers a competitive target bonus, equity, and a comprehensive benefits package.
We are committed to fair pay practices, and we regularly review our compensation programs to ensure they are competitive, equitable, and aligned with our values. Please note that the advertised pay range is not a guarantee or promise of a specific wage.
Triveni Bio, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Official Triveni Bio applications will always be submitted through Lever, our ATS. Any applications that take you to other platforms could be fraudulent. We do not use text or chat applications to conduct interviews or make job offers. Official Triveni Bio correspondence will always be conducted from email addresses ending in @triveni.bio or @hire.lever.co. Please disregard any other communications that do not originate from these domain names. If you receive any suspicious requests or communications, please verify their authenticity before responding.
COMPANY INTRODUCTION
Triveni Bio is breaking new ground in the identification of novel disease targets – working at the convergence of human genetics, best-in-class antibody design, and precision medicine. We are pioneering a Mendelian genetics-informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory (I&I) disorders. Our lead antibody program (TRIV-509) targets kallikreins 5 and 7 (KLK5/7) to directly impact skin barrier function, inflammation, and itch – providing a meaningful and much needed potential treatment option for patients with atopic dermatitis and other barrier disorders. In all the work we do, we adhere to our core values: patient impact, bold and rigorous science, open collaboration, kindness & respect.
SUMMARY
We are seeking a motivated, detail-oriented Senior Scientist to join our Clinical Pharmacology team. In this hands-on role, you will contribute directly to data analysis, modeling, and operational tracking across our clinical-stage and pipeline programs. Working closely with cross-functional teams, you will perform non-compartmental analyses (NCA), population PK/PD modeling, help define and implement bioanalytical strategies, manage bioanalytical data, and actively participate in clinical study team meetings. This is an exciting opportunity for an early-career scientist with 2–3 years of experience looking to expand their skills in hands-on quantitative clinical pharmacology and biologic drug development. Reporting into the Exec. Director, Clinical Pharmacology, and working closely with Clinical Development, Translational Medicine, Biometrics, Regulatory Affairs, and external partners, the Senior Scientist will help generate data and insights that inform dose selection, study design, and key development decisions.
Responsibilities
- Support the development and implementation of clinical pharmacology plans for clinical development programs
- Contribute to the design of PK, PD, biomarker, immunogenicity, and exposure-response assessments in clinical studies
- Perform Non-Compartmental Analysis (NCA) using standard software (e.g., Monolix or R) to support clinical study
- Execute data assembly, dataset generation, and preliminary quantitative analyses for Population PK/PD (popPK/PD) and exposure-response modeling using R, Monolix, or equivalent platforms
- Generate high-quality graphical visualizations and summary tables of clinical PK/PD for internal study team updates
- Attend and participate in cross-functional clinical study team meetings, representing the Clinical Pharmacology function
- Collaborate with internal teams and external vendors to ensure timely execution of clinical pharmacology analyses and deliverables
- Assist in the preparation and review of clinical study protocols, statistical analysis plans, clinical study reports, and other development documents
- Support the preparation of clinical pharmacology components of regulatory submissions and health authority responses
- Contribute to model-informed drug development activities and pharmacometric analyses through collaboration with internal and external experts
- Present study results and data interpretations to project teams and functional leadership
- Maintain knowledge of current scientific, regulatory, and industry trends in clinical pharmacology and pharmacometrics
- Other duties as assigned
EXPERIENCE & QUALIFICATIONS
- Ph.D. or M.S. in Clinical Pharmacology, Pharmaceutical Sciences, Pharmacometrics, Pharmacokinetics, Biomedical Sciences, or a related scientific discipline
- 2+ years (Ph.D.) or 5+ years (M.S.) years of relevant industry experience in biotechnology, pharmaceutical, or CRO environments; postdoctoral experience may be considered
- Proficiency with R for data manipulation, statistical reporting, and data visualization. Hands-on experience or academic exposure to pharmacometric platforms such as Monolix, or NONMEM
- Experience supporting clinical development programs, preferably involving biologics, antibodies, or immunology/inflammation therapeutics
- Knowledge of PK, PD, exposure-response relationships, immunogenicity assessments, and clinical pharmacology principles
- Experience working with external CROs and bioanalytical laboratories
- Strong scientific communication and data presentation skills
- Experience contributing to regulatory documentation is preferred
- Ability to travel up to 10% as needed
The posted range reflects the current reasonable and good faith estimate of the base salary for this full-time position. Actual compensation will be based on a variety of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location and other organizational needs. This role also offers a competitive target bonus, equity, and a comprehensive benefits package.
We are committed to fair pay practices, and we regularly review our compensation programs to ensure they are competitive, equitable, and aligned with our values. Please note that the advertised pay range is not a guarantee or promise of a specific wage.
Triveni Bio, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Official Triveni Bio applications will always be submitted through Lever, our ATS. Any applications that take you to other platforms could be fraudulent. We do not use text or chat applications to conduct interviews or make job offers. Official Triveni Bio correspondence will always be conducted from email addresses ending in @triveni.bio or @hire.lever.co. Please disregard any other communications that do not originate from these domain names. If you receive any suspicious requests or communications, please verify their authenticity before responding.
OPT Technology Job Roles in Massachusetts
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Search Technology Jobs in MassachusettsTechnology OPT Sponsorship Jobs in Massachusetts: Frequently Asked Questions
Which technology companies in Massachusetts commonly sponsor F-1 OPT visas?
Massachusetts has a high concentration of technology employers with established international hiring programs. Companies like HubSpot, Wayfair, MathWorks, PTC, Akamai Technologies, and Raytheon Technologies have histories of hiring F-1 OPT students. Boston's biotech sector, including firms like Biogen and Moderna, also regularly employs OPT holders in software and data engineering roles supporting their research and product infrastructure.
Which cities in Massachusetts have the most technology F-1 OPT sponsorship jobs?
Greater Boston and Cambridge account for the largest share of technology OPT sponsorship opportunities in the state. The Route 128 corridor, spanning Waltham, Burlington, and Lexington, hosts major tech campuses and defense contractors. Worcester has a growing technology sector tied to its university ecosystem. Somerville and Kendall Square in Cambridge are particularly active for startups and life sciences technology roles.
What types of technology roles typically qualify for F-1 OPT sponsorship in Massachusetts?
Roles in software engineering, data science, machine learning, cybersecurity, cloud infrastructure, and product engineering are the most common OPT-eligible positions in Massachusetts. For STEM OPT, your degree field must directly relate to the job. Massachusetts employers in fintech, defense technology, and biotech also hire OPT holders for DevOps, QA engineering, and embedded systems roles where the STEM degree alignment is straightforward to document.
How do I find technology F-1 OPT sponsorship jobs in Massachusetts?
Migrate Mate is built specifically for international students searching for OPT-eligible technology roles, with filters for visa type, state, and industry so you can focus on Massachusetts employers who actively sponsor. Beyond job searching, attending university career fairs at MIT, Northeastern, and Boston University connects you directly with recruiters from local technology firms that have existing OPT hiring pipelines.
Are there any Massachusetts-specific considerations for F-1 OPT students in the technology industry?
Massachusetts employers in defense and government contracting, including many Route 128 firms, often require security clearances that F-1 OPT holders are generally not eligible for, which can limit certain roles. However, the commercial technology sector in Boston and Cambridge is highly international-student-friendly. Massachusetts is also a STEM-designated degree state in many universities, meaning graduates frequently qualify for the 24-month STEM OPT extension, giving employers a longer window to pursue H-1B visa sponsorship.