Technology H-1B Sponsorship Jobs in Massachusetts
Massachusetts is one of the strongest states for H-1B visa technology sponsorship, anchored by major employers in Greater Boston including Microsoft, Amazon, Google, IBM, and thousands of biotech and enterprise software firms. The Route 128 corridor and Cambridge's Kendall Square concentration mean consistent demand for software engineers, data scientists, and cloud architects requiring H-1B support.
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Get Access To All JobsCOMPANY INTRODUCTION
Triveni Bio is breaking new ground in the identification of novel disease targets – working at the convergence of human genetics, best-in-class antibody design, and precision medicine. We are pioneering a Mendelian genetics-informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory (I&I) disorders. Our lead antibody program (TRIV-509) targets kallikreins 5 and 7 (KLK5/7) to directly impact skin barrier function, inflammation, and itch – providing a meaningful and much needed potential treatment option for patients with atopic dermatitis and other barrier disorders. In all the work we do, we adhere to our core values: patient impact, bold and rigorous science, open collaboration, kindness & respect.
SUMMARY
We are seeking a motivated, detail-oriented Senior Scientist to join our Clinical Pharmacology team. In this hands-on role, you will contribute directly to data analysis, modeling, and operational tracking across our clinical-stage and pipeline programs. Working closely with cross-functional teams, you will perform non-compartmental analyses (NCA), population PK/PD modeling, help define and implement bioanalytical strategies, manage bioanalytical data, and actively participate in clinical study team meetings. This is an exciting opportunity for an early-career scientist with 2–3 years of experience looking to expand their skills in hands-on quantitative clinical pharmacology and biologic drug development. Reporting into the Exec. Director, Clinical Pharmacology, and working closely with Clinical Development, Translational Medicine, Biometrics, Regulatory Affairs, and external partners, the Senior Scientist will help generate data and insights that inform dose selection, study design, and key development decisions.
Responsibilities
- Support the development and implementation of clinical pharmacology plans for clinical development programs
- Contribute to the design of PK, PD, biomarker, immunogenicity, and exposure-response assessments in clinical studies
- Perform Non-Compartmental Analysis (NCA) using standard software (e.g., Monolix or R) to support clinical study
- Execute data assembly, dataset generation, and preliminary quantitative analyses for Population PK/PD (popPK/PD) and exposure-response modeling using R, Monolix, or equivalent platforms
- Generate high-quality graphical visualizations and summary tables of clinical PK/PD for internal study team updates
- Attend and participate in cross-functional clinical study team meetings, representing the Clinical Pharmacology function
- Collaborate with internal teams and external vendors to ensure timely execution of clinical pharmacology analyses and deliverables
- Assist in the preparation and review of clinical study protocols, statistical analysis plans, clinical study reports, and other development documents
- Support the preparation of clinical pharmacology components of regulatory submissions and health authority responses
- Contribute to model-informed drug development activities and pharmacometric analyses through collaboration with internal and external experts
- Present study results and data interpretations to project teams and functional leadership
- Maintain knowledge of current scientific, regulatory, and industry trends in clinical pharmacology and pharmacometrics
- Other duties as assigned
EXPERIENCE & QUALIFICATIONS
- Ph.D. or M.S. in Clinical Pharmacology, Pharmaceutical Sciences, Pharmacometrics, Pharmacokinetics, Biomedical Sciences, or a related scientific discipline
- 2+ years (Ph.D.) or 5+ years (M.S.) years of relevant industry experience in biotechnology, pharmaceutical, or CRO environments; postdoctoral experience may be considered
- Proficiency with R for data manipulation, statistical reporting, and data visualization. Hands-on experience or academic exposure to pharmacometric platforms such as Monolix, or NONMEM
- Experience supporting clinical development programs, preferably involving biologics, antibodies, or immunology/inflammation therapeutics
- Knowledge of PK, PD, exposure-response relationships, immunogenicity assessments, and clinical pharmacology principles
- Experience working with external CROs and bioanalytical laboratories
- Strong scientific communication and data presentation skills
- Experience contributing to regulatory documentation is preferred
- Ability to travel up to 10% as needed
The posted range reflects the current reasonable and good faith estimate of the base salary for this full-time position. Actual compensation will be based on a variety of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location and other organizational needs. This role also offers a competitive target bonus, equity, and a comprehensive benefits package.
We are committed to fair pay practices, and we regularly review our compensation programs to ensure they are competitive, equitable, and aligned with our values. Please note that the advertised pay range is not a guarantee or promise of a specific wage.
Triveni Bio, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Official Triveni Bio applications will always be submitted through Lever, our ATS. Any applications that take you to other platforms could be fraudulent. We do not use text or chat applications to conduct interviews or make job offers. Official Triveni Bio correspondence will always be conducted from email addresses ending in @triveni.bio or @hire.lever.co. Please disregard any other communications that do not originate from these domain names. If you receive any suspicious requests or communications, please verify their authenticity before responding.
COMPANY INTRODUCTION
Triveni Bio is breaking new ground in the identification of novel disease targets – working at the convergence of human genetics, best-in-class antibody design, and precision medicine. We are pioneering a Mendelian genetics-informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory (I&I) disorders. Our lead antibody program (TRIV-509) targets kallikreins 5 and 7 (KLK5/7) to directly impact skin barrier function, inflammation, and itch – providing a meaningful and much needed potential treatment option for patients with atopic dermatitis and other barrier disorders. In all the work we do, we adhere to our core values: patient impact, bold and rigorous science, open collaboration, kindness & respect.
SUMMARY
We are seeking a motivated, detail-oriented Senior Scientist to join our Clinical Pharmacology team. In this hands-on role, you will contribute directly to data analysis, modeling, and operational tracking across our clinical-stage and pipeline programs. Working closely with cross-functional teams, you will perform non-compartmental analyses (NCA), population PK/PD modeling, help define and implement bioanalytical strategies, manage bioanalytical data, and actively participate in clinical study team meetings. This is an exciting opportunity for an early-career scientist with 2–3 years of experience looking to expand their skills in hands-on quantitative clinical pharmacology and biologic drug development. Reporting into the Exec. Director, Clinical Pharmacology, and working closely with Clinical Development, Translational Medicine, Biometrics, Regulatory Affairs, and external partners, the Senior Scientist will help generate data and insights that inform dose selection, study design, and key development decisions.
Responsibilities
- Support the development and implementation of clinical pharmacology plans for clinical development programs
- Contribute to the design of PK, PD, biomarker, immunogenicity, and exposure-response assessments in clinical studies
- Perform Non-Compartmental Analysis (NCA) using standard software (e.g., Monolix or R) to support clinical study
- Execute data assembly, dataset generation, and preliminary quantitative analyses for Population PK/PD (popPK/PD) and exposure-response modeling using R, Monolix, or equivalent platforms
- Generate high-quality graphical visualizations and summary tables of clinical PK/PD for internal study team updates
- Attend and participate in cross-functional clinical study team meetings, representing the Clinical Pharmacology function
- Collaborate with internal teams and external vendors to ensure timely execution of clinical pharmacology analyses and deliverables
- Assist in the preparation and review of clinical study protocols, statistical analysis plans, clinical study reports, and other development documents
- Support the preparation of clinical pharmacology components of regulatory submissions and health authority responses
- Contribute to model-informed drug development activities and pharmacometric analyses through collaboration with internal and external experts
- Present study results and data interpretations to project teams and functional leadership
- Maintain knowledge of current scientific, regulatory, and industry trends in clinical pharmacology and pharmacometrics
- Other duties as assigned
EXPERIENCE & QUALIFICATIONS
- Ph.D. or M.S. in Clinical Pharmacology, Pharmaceutical Sciences, Pharmacometrics, Pharmacokinetics, Biomedical Sciences, or a related scientific discipline
- 2+ years (Ph.D.) or 5+ years (M.S.) years of relevant industry experience in biotechnology, pharmaceutical, or CRO environments; postdoctoral experience may be considered
- Proficiency with R for data manipulation, statistical reporting, and data visualization. Hands-on experience or academic exposure to pharmacometric platforms such as Monolix, or NONMEM
- Experience supporting clinical development programs, preferably involving biologics, antibodies, or immunology/inflammation therapeutics
- Knowledge of PK, PD, exposure-response relationships, immunogenicity assessments, and clinical pharmacology principles
- Experience working with external CROs and bioanalytical laboratories
- Strong scientific communication and data presentation skills
- Experience contributing to regulatory documentation is preferred
- Ability to travel up to 10% as needed
The posted range reflects the current reasonable and good faith estimate of the base salary for this full-time position. Actual compensation will be based on a variety of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location and other organizational needs. This role also offers a competitive target bonus, equity, and a comprehensive benefits package.
We are committed to fair pay practices, and we regularly review our compensation programs to ensure they are competitive, equitable, and aligned with our values. Please note that the advertised pay range is not a guarantee or promise of a specific wage.
Triveni Bio, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Official Triveni Bio applications will always be submitted through Lever, our ATS. Any applications that take you to other platforms could be fraudulent. We do not use text or chat applications to conduct interviews or make job offers. Official Triveni Bio correspondence will always be conducted from email addresses ending in @triveni.bio or @hire.lever.co. Please disregard any other communications that do not originate from these domain names. If you receive any suspicious requests or communications, please verify their authenticity before responding.
H-1B Technology Job Roles in Massachusetts
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Search Technology Jobs in MassachusettsTechnology H-1B Sponsorship Jobs in Massachusetts: Frequently Asked Questions
Which technology companies sponsor H-1B visas in Massachusetts?
Massachusetts has a deep pool of H-1B visa technology sponsors. Large employers with consistent filings include Amazon, Microsoft, Google, IBM, Oracle, and Wayfair. Mid-size and growth-stage companies in Kendall Square and along the Route 128 corridor, including many enterprise software and cybersecurity firms, also file regularly. Biotech-adjacent technology roles at companies like Moderna and Biogen are another source of H-1B filings in the state.
Which cities in Massachusetts have the most technology H-1B sponsorship jobs?
Greater Boston, particularly Cambridge, is the primary hub, with Kendall Square hosting a high concentration of software, AI, and cloud companies. Boston itself, Waltham, Burlington, and Woburn along the Route 128 tech corridor are also strong markets. Worcester has a growing technology sector, and Springfield-area employers contribute a smaller share of H-1B technology filings.
What types of technology roles typically qualify for H-1B sponsorship?
Roles that commonly meet the H-1B specialty occupation requirement in technology include software engineers, data scientists, machine learning engineers, DevOps and cloud infrastructure engineers, cybersecurity analysts, and product managers with a technical degree requirement. The role must require at least a bachelor's degree in a specific technical field as a minimum entry requirement. Generalist roles where any degree suffices are less likely to qualify.
How do I find technology H-1B sponsorship jobs in Massachusetts?
Migrate Mate filters job listings specifically by visa sponsorship type and state, making it straightforward to browse technology H-1B roles in Massachusetts without sifting through positions that don't sponsor. You can narrow results by city, role type, and company. Because Massachusetts has one of the highest concentrations of H-1B technology employers in the country, there are consistently active listings across software, data, and infrastructure specializations.
Are there any state-specific considerations for H-1B technology workers in Massachusetts?
Massachusetts does not have state-level visa or work authorization requirements beyond federal H-1B rules, but a few practical points matter. The state has a non-compete law that limits enforcement of non-compete agreements, which is relevant for technology workers moving between employers. Massachusetts also taxes H-1B holders as residents if they meet the 183-day presence threshold, so understanding state income tax obligations from day one is worthwhile.
What is the prevailing wage for H-1B technology jobs in Massachusetts?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.