Biotech & Pharma Green Card Sponsorship Jobs in South Dakota
South Dakota's biotech and pharma sector is anchored by employers such as Sanford Health and South Dakota State University's research programs, with Sioux Falls and Brookings as the primary hiring centers. Green Card sponsorship in this field typically follows the PERM labor certification route for research scientists, regulatory affairs specialists, and biomanufacturing roles requiring advanced degrees.
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We are seeking a highly motivated Principal Scientist I with extensive AAV gene therapy manufacturing experience to develop state-of-the-art downstream purification processes for next-generation AAV gene therapy. This role is also responsible for executing early-stage process development with the focus on developability of AAV gene therapy lead candidates as well as new platform process development for existing and novel AAV capsids and cargo vectors.
About The Role
Internal Job Title: Principal Scientist I/II
Position Location: Onsite, San Diego, CA
Key Responsibilities
- Lead and manage a 3-5 person downstream process team and provide technical support, training, and SME knowledge to assist with the professional development of direct reports.
- Coordinate activities with associates across upstream process and analytical teams.
- Develop strategies in collaboration with Disease Areas and partner with various line functions to support early drug discovery from target selection and validation through lead compound selection and developability assessment.
- Serve as a subject matter expert to transfer manufacturing process knowledge to Technical Research & Development team and advance pipeline programs into clinical phases.
- Lead effort and work collaboratively with Technical Research & Development to develop innovative and cost-effective downstream processes for next-generation AAV.
- Manage multiple project workflow to ensure timely delivery.
- Prepare written reports conforming to defined documentation practices including electronic lab notebook.
- Other related duties as assigned.
Essential Requirements
- PhD in bioprocessing, biochemical engineering, gene therapy or a related field with 3+ years of relevant process development experience in biotechnology/pharmaceutical environment.
- Experience in people management.
- Knowledge of downstream purification processes including affinity and ion-exchange chromatography with hands-on experience with AKTA purification systems.
- Technical proficiency, creativity, and independent thoughts.
- Effective communication skills to convey scientific concepts to research scientists and cross-functional collaborators.
- Strong organization and problem-solving skills with attention to details.
- Ability to work in a fast-paced and matrix environment.
Desired Requirements
- Experiences in AAV gene therapy.
- Experience with viral gene therapy.
The salary for this position is expected to range between $108,500 and $201,500 per year for Principal Scientist I, and between $119,700 and $222,300 per year for Principal Scientist II. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
To learn more about the culture, rewards and benefits we offer our people click here.
Why Novartis:
Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?
Benefits and Rewards:
Learn about all the ways we’ll help you thrive personally and professionally. Read our handbook (PDF 30 MB)
EEO Statement
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Summary
We are seeking a highly motivated Principal Scientist I with extensive AAV gene therapy manufacturing experience to develop state-of-the-art downstream purification processes for next-generation AAV gene therapy. This role is also responsible for executing early-stage process development with the focus on developability of AAV gene therapy lead candidates as well as new platform process development for existing and novel AAV capsids and cargo vectors.
About The Role
Internal Job Title: Principal Scientist I/II
Position Location: Onsite, San Diego, CA
Key Responsibilities
- Lead and manage a 3-5 person downstream process team and provide technical support, training, and SME knowledge to assist with the professional development of direct reports.
- Coordinate activities with associates across upstream process and analytical teams.
- Develop strategies in collaboration with Disease Areas and partner with various line functions to support early drug discovery from target selection and validation through lead compound selection and developability assessment.
- Serve as a subject matter expert to transfer manufacturing process knowledge to Technical Research & Development team and advance pipeline programs into clinical phases.
- Lead effort and work collaboratively with Technical Research & Development to develop innovative and cost-effective downstream processes for next-generation AAV.
- Manage multiple project workflow to ensure timely delivery.
- Prepare written reports conforming to defined documentation practices including electronic lab notebook.
- Other related duties as assigned.
Essential Requirements
- PhD in bioprocessing, biochemical engineering, gene therapy or a related field with 3+ years of relevant process development experience in biotechnology/pharmaceutical environment.
- Experience in people management.
- Knowledge of downstream purification processes including affinity and ion-exchange chromatography with hands-on experience with AKTA purification systems.
- Technical proficiency, creativity, and independent thoughts.
- Effective communication skills to convey scientific concepts to research scientists and cross-functional collaborators.
- Strong organization and problem-solving skills with attention to details.
- Ability to work in a fast-paced and matrix environment.
Desired Requirements
- Experiences in AAV gene therapy.
- Experience with viral gene therapy.
The salary for this position is expected to range between $108,500 and $201,500 per year for Principal Scientist I, and between $119,700 and $222,300 per year for Principal Scientist II. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
To learn more about the culture, rewards and benefits we offer our people click here.
Why Novartis:
Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?
Benefits and Rewards:
Learn about all the ways we’ll help you thrive personally and professionally. Read our handbook (PDF 30 MB)
EEO Statement
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Green Card Biotech & Pharma Job Roles in South Dakota
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Search Biotech & Pharma Jobs in South DakotaBiotech & Pharma Green Card Sponsorship Jobs in South Dakota: Frequently Asked Questions
Which biotech & pharma companies sponsor Green Card visas in South Dakota?
Sanford Health, one of the largest health systems in the region, has sponsored Green Cards for research and clinical positions. Pharmaceutical distribution and specialty biotech firms operating in Sioux Falls and Rapid City also appear in PERM labor certification filings. Because South Dakota's biotech sector is smaller than coastal hubs, sponsored roles tend to concentrate in research institutions, hospital-affiliated labs, and medical device manufacturers rather than large standalone pharma corporations.
Which cities in South Dakota have the most biotech & pharma Green Card sponsorship jobs?
Sioux Falls accounts for the largest share of biotech and pharma employment in South Dakota, driven by Sanford Health's research operations and a growing cluster of life sciences suppliers. Brookings is the second-most active city, anchored by South Dakota State University's agricultural biotechnology and pharmaceutical sciences programs. Rapid City has a smaller but present medical and biotech employer base, particularly in diagnostics and healthcare technology.
What types of biotech & pharma roles typically qualify for Green Card sponsorship in South Dakota?
Roles requiring a master's degree or doctorate in life sciences, biochemistry, pharmaceutical sciences, or biomedical engineering are the most common Green Card-sponsored positions. Research scientists, principal investigators, regulatory affairs managers, quality assurance specialists, and bioinformatics analysts typically qualify under EB-2 or EB-3 classifications. Positions with highly specialized requirements and limited domestic applicant pools are more likely to proceed through PERM labor certification, the standard pathway for employer-sponsored permanent residence.
How do I find biotech & pharma Green Card sponsorship jobs in South Dakota?
Migrate Mate lets you filter specifically for biotech and pharma roles in South Dakota that include Green Card sponsorship, drawing on DOL labor certification data to surface employers with verified sponsorship history. This is more targeted than a general job search because it filters out positions where sponsorship is unlikely. You can narrow results by city, role type, and degree requirement to match South Dakota employers actively filing PERM applications in the life sciences sector.
Are there state-specific considerations for Green Card sponsorship in South Dakota's biotech sector?
South Dakota has no state income tax, which affects total compensation calculations that employers use when benchmarking against DOL prevailing wage requirements under PERM. The state's relatively small biotech footprint means fewer competing PERM filings per occupation, but it also means fewer employers with established sponsorship infrastructure. Candidates targeting research-intensive roles should review prevailing wage levels for their specific Standard Occupational Classification code using the OFLC Wage Search to understand what certified wage offers in South Dakota look like before applying.
What is the prevailing wage for Green Card biotech & pharma jobs in South Dakota?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.