Clinical Operations Director Jobs in USA with Visa Sponsorship

Clinical Operations Director roles qualify for H-1B visa sponsorship as a specialty occupation requiring a directly related bachelor's degree or higher. Employers filing an LCA must meet DOL prevailing wage requirements, and most large health systems and CROs have active sponsorship history for this title. For detailed occupation requirements, see the O*NET profile.

Find Clinical Operations Director Jobs

Overview

Open Jobs8,054+
Top Visa TypeH-1B
Work Type86% On-site
Top LocationRemote
Most JobsOptum

Showing 5 of 8,054+ Clinical Operations Director jobs

Director Clinical Operations
We won't show you this job again
Added 1d ago
Director Clinical Operations
WVU Medicine
Morgantown, West Virginia
Healthcare Administration
Human Resources
Project & Program Management
Customer Service & Support
Customer Service
On-Site
Bachelor's
10,000+

Have you applied for this role?

Senior Director, DOM AMC Clinical Operations
We won't show you this job again
Added 1d ago
Senior Director, DOM AMC Clinical Operations
Mass General Brigham
Boston, Massachusetts
Healthcare Administration
Project & Program Management
Human Resources
Business Operations
$124k - $181k/yr
Hybrid
Bachelor's
10,000+

Have you applied for this role?

Director, Clinical Operations
We won't show you this job again
Added 1d ago
Director, Clinical Operations
Relay Therapeutics
Cambridge, Massachusetts
Healthcare Administration
Project & Program Management
Project Management
On-Site
Bachelor's
201-500

Have you applied for this role?

Director of Clinical Operations
We won't show you this job again
Added 2d ago
Director of Clinical Operations
Monogram Health
Remote
Project & Program Management
Healthcare Administration
Project Management
Program Management
$136k - $169k/yr
Remote (US)
Bachelor's
1,001-5,000

Have you applied for this role?

Executive Director, Clinical Operations
We won't show you this job again
Added 2d ago
Executive Director, Clinical Operations
Fate Therapeutics Inc.
San Diego, California
Project & Program Management
Healthcare Administration
Project Management
$300k/yr
On-Site
Bachelor's

Have you applied for this role?

See all 8,054+ Clinical Operations Director Jobs

Sign up for free to unlock all listings, filter by visa type, and get alerts for new Clinical Operations Director roles.

Get Access To All Jobs

See all 8,054+ Clinical Operations Director Jobs

Sign up for free to unlock all listings, filter by visa type, and get alerts for new Clinical Operations Director roles.

Get Access To All Jobs

Tips for Finding Clinical Operations Director Jobs

Align your degree to the role

USCIS requires your degree to be in a field directly related to clinical operations, such as healthcare administration, life sciences, or nursing. A general business degree alone may trigger an RFE, so document any graduate coursework that bridges the gap.

Target CROs and health systems first

Contract research organizations and large integrated health systems file LCAs for Clinical Operations Directors most consistently. These employers have established immigration counsel and are more likely to run a full sponsorship process than mid-size specialty clinics or startups.

Search verified sponsors on Migrate Mate

Use Migrate Mate to find employers with confirmed LCA filing history for clinical operations roles, searchable by city and seniority. This cuts the time you'd otherwise spend manually filtering OFLC public disclosure data.

Check prevailing wage before salary talks

Your employer's LCA must certify a wage at or above the DOL prevailing wage for your location and role level. Run the OFLC Wage Search before negotiations so you know the floor, and flag any offer that sits below it as a sponsorship risk.

Expect PERM if you're pursuing a green card

Most EB-2 and EB-3 green card paths for this role require PERM labor certification, where DOL audits the employer's recruitment process. Directors with niche therapeutic area expertise sometimes qualify for EB-2 National Interest Waiver, which skips PERM entirely.

Review the O*NET profile before interviews

The O*NET occupation profile for Medical and Health Services Managers defines the core duties USCIS uses to evaluate specialty occupation eligibility. Make sure your resume and job description language matches those defined duties to reduce RFE risk.

Frequently Asked Questions

Does a Clinical Operations Director role qualify as a specialty occupation for H-1B purposes?

Yes, provided the employer documents that the role requires a bachelor's degree or higher in a directly related field such as healthcare administration, clinical sciences, or a related discipline. USCIS scrutinizes director-level titles more closely when duties overlap with general management, so the job description needs to emphasize clinical and regulatory expertise, not just supervisory responsibilities.

Which visa types are realistic for a Clinical Operations Director seeking sponsorship?

H-1B is the most common path for this role, covering initial status of up to three years and extendable to six. Australian citizens can apply for an E-3 visa without entering the lottery. Canadian and Mexican nationals may qualify under TN visa if the role maps to an eligible USMCA profession. For longer-term options, EB-2 or EB-3 green card sponsorship through PERM is available from employers willing to commit to the process.

How do I find employers who actively sponsor Clinical Operations Directors?

Migrate Mate lists U.S. employers with verified LCA filing history for clinical operations roles, searchable by location and role type. This is the most direct way to identify which health systems, CROs, and biopharma companies have sponsored this title rather than relying on job postings that may not reflect actual sponsorship willingness.

Will my overseas clinical operations experience count toward H-1B eligibility?

USCIS accepts foreign work experience as a substitute for formal education under the three-for-one rule: three years of progressively responsible experience in clinical operations can substitute for one year of a bachelor's degree. If your degree is in an unrelated field, you'll need a detailed credentials evaluation and experience letters from former employers to build the specialty occupation case.

Does the H-1B cap and lottery apply to Clinical Operations Director roles?

H-1B is subject to an annual cap and selection process, and the selection rules have changed recently. However, cap-exempt employers, including certain nonprofit hospitals, university medical centers, and research institutions affiliated with higher education, can file H-1B petitions outside the cap at any time of year, which is worth confirming directly with potential employers in those categories.

What is the prevailing wage requirement for sponsored Clinical Operations Director jobs?

U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.