Clinical Trial Manager Jobs in USA with Visa Sponsorship
Clinical Trial Managers are in high demand across U.S. biotech, pharma, and CROs, and most employers in this space have established H-1B visa and E-3 visa sponsorship pipelines. A master's degree or bachelor's in life sciences with several years of CRA experience is the typical qualifying profile. For detailed occupation requirements, see the O*NET profile.
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BSD ALL - Research
About the Department
The Alliance for Clinical Trials in Oncology (Alliance) is a National Cancer Institute (NCI) sponsored research organization with over 100 member networks (over 1200 research sites). The Alliance for Clinical Trials in Oncology at the University of Chicago serves as the office for scientific protocol, administrative, regulatory and pharmaceutical affairs operations of the Alliance.
Job Summary
The Clinical Trials Manager will manage and coordinate a variety of complex and independent activities involved with planning and conducting multiple research studies for the Alliance. The Central Protocol Operations Program is a program within the Alliance for Clinical Trials in Oncology, a national cooperative group sponsored by the National Cancer Institute. The Clinical Trials Manager serves as an in-house manager who oversees protocol coordinators who are responsible for developing research protocols in a timely and efficient manner.
Responsibilities
- Assist the Director of Protocol Operations in assessing overall workload and assigning committee and study responsibilities.
- Train, direct and monitor the work of protocol coordinators to ensure accuracy and adherence to external and internal timelines.
- Conduct meetings with assigned protocol coordinators, and, on occasion, senior protocol coordinators, to implement and ensure compliance with standard operating procedures.
- Manage vacation, sick leave, and other absences, as well as annual employee evaluation process for assigned protocol coordinators with oversight from Director of Protocol Operations. Assist the Director of Protocol Operations in the selection of candidates and in hiring process for new protocol coordinators.
- Assist the Director of Protocol Operations in the development and implementation of relevant policies, procedures, and guidelines for protocol operations.
- Assist the Director of Protocol Operations in the execution of the Central Protocol Operation Program’s mission statement, as well as the Alliance’s overall strategic plan.
- Manage committee activities and committee study teams in the development and implementation of Alliance protocols.
- Draft protocol and consent documents, model protocol templates, ensuring compliance with federal guidelines, the Alliance model protocol, and current Alliance policy and procedures.
- Format, proofread, and edit protocols for designated committee assignments.
- Distribute protocol drafts for review, integrate technical and scientific information from multiple sources and incorporate necessary revisions under the supervision of Alliance Executive Officers and other senior leadership, as necessary.
- Work with Alliance Executive Officers and other senior leadership, as necessary, to identify and resolve impediments to protocol development process.
- Act as liaison to funding agencies (NCI CTEP and DCP staff), the Cancer Trials Support Unit (CTSU), and the NCI Central Institutional Review Board (CIRB), regarding studies in development or undergoing revision, and monitor progress of review performed by these organizations. Identify and seek resolution of issues raised during the course of review by these agencies.
- In collaboration with study team, prepare response to reviews, make all necessary revisions to the protocol document, and submit all necessary supporting documentation.
- In conjunction with Executive Officer and Director of Pharmaceutical and Regulatory Affairs, ensure that protocols meet pharmaceutical collaborator requirements.
- Prepare amendments for active protocols as necessary.
- Obtain necessary approvals, including submission, if necessary to the Alliance Data and Safety Monitoring Board, other Alliance committees charged with oversight and approval, the CIRB, and NCI CTEP/DCP.
- Prepare and distribute amendments to the group membership.
- Identify emergent issues arising during development and implementation of studies and seek resolution of such issues. Implement emergency procedures, as required, in conjunction with Executive Officers, Director of Protocol Operations, Director of Pharmaceutical and Regulatory Affairs, etc.
- Field telephone and email inquiries regarding study conduct from clinical research and health-related professionals, including data managers, nurses, and physicians.
- Attend group meetings, core committee meetings and other meetings as assigned.
- Report at meetings, as necessary, the status of protocols under development or in progress.
- Provide information and assistance regarding protocol development procedures.
- Coordinates events, researches logistics, assists with planning and preparing presentations, event outreach, and post-event write ups.
- Assists with other administrative projects as needed and acquire higher level guidance and skills.
- Performs other related work as needed.
Minimum Qualifications
Education:
Minimum requirements include a college or university degree in related field.
Work Experience:
Minimum requirements include knowledge and skills developed through 2-5 years of work experience in a related job discipline.
Certifications:
Preferred Qualifications
Education:
- Master’s degree in biology, public health or in another scientific or health-related field is strongly preferred.
- Bachelor’s degree will be considered if accompanied by a minimum of 4 years of experience in oncology clinical trials in an academic or community medical center or pharmaceutical industry.
Experience:
- Experience in research or scientific writing.
- Experience with clinical trials research.
Preferred Competencies
- Must have the ability to communicate well with group members, as well as representatives from industry and federal agencies.
- Must have excellent verbal and written communication skills demonstrated in a research or scientific setting.
- Must have the ability to handle multiple tasks and assignments simultaneously.
- Must have excellent organizational and leadership skills.
Working Conditions
- Must be willing to travel approximately 5% of the year.
Application Documents
- Resume (required)
When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.
Job Family
Administration & Management
Role Impact
Individual Contributor
Scheduled Weekly Hours
40
Drug Test Required
No
Health Screen Required
No
Motor Vehicle Record Inquiry Required
No
Pay Rate Type
Salary
FLSA Status
Exempt
Pay Range
$60,000.00 - $85,000.00
The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.
Benefits Eligible
Yes
The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.
The University of Chicago is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.
Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.
All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.
The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: http://securityreport.uchicago.edu. Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.
Department
BSD ALL - Research
About the Department
The Alliance for Clinical Trials in Oncology (Alliance) is a National Cancer Institute (NCI) sponsored research organization with over 100 member networks (over 1200 research sites). The Alliance for Clinical Trials in Oncology at the University of Chicago serves as the office for scientific protocol, administrative, regulatory and pharmaceutical affairs operations of the Alliance.
Job Summary
The Clinical Trials Manager will manage and coordinate a variety of complex and independent activities involved with planning and conducting multiple research studies for the Alliance. The Central Protocol Operations Program is a program within the Alliance for Clinical Trials in Oncology, a national cooperative group sponsored by the National Cancer Institute. The Clinical Trials Manager serves as an in-house manager who oversees protocol coordinators who are responsible for developing research protocols in a timely and efficient manner.
Responsibilities
- Assist the Director of Protocol Operations in assessing overall workload and assigning committee and study responsibilities.
- Train, direct and monitor the work of protocol coordinators to ensure accuracy and adherence to external and internal timelines.
- Conduct meetings with assigned protocol coordinators, and, on occasion, senior protocol coordinators, to implement and ensure compliance with standard operating procedures.
- Manage vacation, sick leave, and other absences, as well as annual employee evaluation process for assigned protocol coordinators with oversight from Director of Protocol Operations. Assist the Director of Protocol Operations in the selection of candidates and in hiring process for new protocol coordinators.
- Assist the Director of Protocol Operations in the development and implementation of relevant policies, procedures, and guidelines for protocol operations.
- Assist the Director of Protocol Operations in the execution of the Central Protocol Operation Program’s mission statement, as well as the Alliance’s overall strategic plan.
- Manage committee activities and committee study teams in the development and implementation of Alliance protocols.
- Draft protocol and consent documents, model protocol templates, ensuring compliance with federal guidelines, the Alliance model protocol, and current Alliance policy and procedures.
- Format, proofread, and edit protocols for designated committee assignments.
- Distribute protocol drafts for review, integrate technical and scientific information from multiple sources and incorporate necessary revisions under the supervision of Alliance Executive Officers and other senior leadership, as necessary.
- Work with Alliance Executive Officers and other senior leadership, as necessary, to identify and resolve impediments to protocol development process.
- Act as liaison to funding agencies (NCI CTEP and DCP staff), the Cancer Trials Support Unit (CTSU), and the NCI Central Institutional Review Board (CIRB), regarding studies in development or undergoing revision, and monitor progress of review performed by these organizations. Identify and seek resolution of issues raised during the course of review by these agencies.
- In collaboration with study team, prepare response to reviews, make all necessary revisions to the protocol document, and submit all necessary supporting documentation.
- In conjunction with Executive Officer and Director of Pharmaceutical and Regulatory Affairs, ensure that protocols meet pharmaceutical collaborator requirements.
- Prepare amendments for active protocols as necessary.
- Obtain necessary approvals, including submission, if necessary to the Alliance Data and Safety Monitoring Board, other Alliance committees charged with oversight and approval, the CIRB, and NCI CTEP/DCP.
- Prepare and distribute amendments to the group membership.
- Identify emergent issues arising during development and implementation of studies and seek resolution of such issues. Implement emergency procedures, as required, in conjunction with Executive Officers, Director of Protocol Operations, Director of Pharmaceutical and Regulatory Affairs, etc.
- Field telephone and email inquiries regarding study conduct from clinical research and health-related professionals, including data managers, nurses, and physicians.
- Attend group meetings, core committee meetings and other meetings as assigned.
- Report at meetings, as necessary, the status of protocols under development or in progress.
- Provide information and assistance regarding protocol development procedures.
- Coordinates events, researches logistics, assists with planning and preparing presentations, event outreach, and post-event write ups.
- Assists with other administrative projects as needed and acquire higher level guidance and skills.
- Performs other related work as needed.
Minimum Qualifications
Education:
Minimum requirements include a college or university degree in related field.
Work Experience:
Minimum requirements include knowledge and skills developed through 2-5 years of work experience in a related job discipline.
Certifications:
Preferred Qualifications
Education:
- Master’s degree in biology, public health or in another scientific or health-related field is strongly preferred.
- Bachelor’s degree will be considered if accompanied by a minimum of 4 years of experience in oncology clinical trials in an academic or community medical center or pharmaceutical industry.
Experience:
- Experience in research or scientific writing.
- Experience with clinical trials research.
Preferred Competencies
- Must have the ability to communicate well with group members, as well as representatives from industry and federal agencies.
- Must have excellent verbal and written communication skills demonstrated in a research or scientific setting.
- Must have the ability to handle multiple tasks and assignments simultaneously.
- Must have excellent organizational and leadership skills.
Working Conditions
- Must be willing to travel approximately 5% of the year.
Application Documents
- Resume (required)
When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.
Job Family
Administration & Management
Role Impact
Individual Contributor
Scheduled Weekly Hours
40
Drug Test Required
No
Health Screen Required
No
Motor Vehicle Record Inquiry Required
No
Pay Rate Type
Salary
FLSA Status
Exempt
Pay Range
$60,000.00 - $85,000.00
The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.
Benefits Eligible
Yes
The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.
The University of Chicago is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.
Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.
All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.
The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: http://securityreport.uchicago.edu. Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.
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Get Access To All JobsTips for Finding Visa Sponsorship as a Clinical Trial Manager
Target CROs and large pharma first
Contract research organizations like ICON, Syneos, and Medpace file H-1B petitions at scale every year. Their established legal infrastructure makes sponsorship smoother and faster than pursuing smaller biotech startups with no prior sponsorship history.
Confirm your degree field matches the role
USCIS treats CTM roles as specialty occupations requiring a degree in life sciences, nursing, pharmacy, or a closely related field. A general business or unrelated science degree may not satisfy the specialty occupation requirement without additional documentation.
Get your GCP and ICH certifications current
Good Clinical Practice certification is a baseline expectation for CTM roles in the U.S. Having current, verifiable GCP training signals readiness to start quickly and reduces employer hesitation around the time and cost of sponsorship.
Raise sponsorship after demonstrating therapeutic fit
Employers weigh therapeutic area experience heavily for CTM roles. Leading with your oncology, neurology, or rare disease background before the sponsorship conversation shifts the focus to your value, making cost and visa complexity feel secondary.
Understand the LCA wage requirement upfront
Every H-1B petition requires a Labor Condition Application certifying the offered wage meets the prevailing wage for the role and location. Knowing this process reassures employers that sponsorship has clear legal guardrails and is not an open-ended financial commitment.
Use Migrate Mate to find sponsorship-open roles
Most job postings don't advertise visa sponsorship directly. Migrate Mate filters specifically for employers willing to sponsor, so you're not wasting applications on companies that won't engage with international candidates at the offer stage.
Clinical Trial Manager jobs are hiring across the US. Find yours.
Find Clinical Trial Manager JobsFrequently Asked Questions
Do Clinical Trial Manager roles typically qualify for H-1B sponsorship?
Yes. CTM positions qualify as specialty occupations under the H-1B because they require at minimum a bachelor's degree in a specific field such as life sciences, pharmacy, or nursing. USCIS has consistently approved H-1B petitions for this title, particularly when the job description includes protocol oversight, site management, and clinical data responsibilities tied to a relevant degree.
What degree do I need for an employer to sponsor my visa as a CTM?
A bachelor's degree in life sciences, nursing, pharmacy, public health, or a closely related field is the baseline. Many employers and USCIS adjudicators look for degrees in biology, biochemistry, or clinical research specifically. A degree in a loosely related field may require a credential evaluation or supporting documentation to establish the degree-to-job connection required for specialty occupation approval.
Are Australian Clinical Trial Managers eligible for the E-3 visa?
Yes. Australian citizens with a qualifying degree and a U.S. employer willing to file a Labor Condition Application can apply for the E-3 visa, which has no annual lottery. CTM roles meet the specialty occupation standard the E-3 requires. The E-3 is issued in two-year increments and can be renewed indefinitely, making it a stable long-term option for Australians working in clinical operations.
How competitive is it to get H-1B sponsorship as a Clinical Trial Manager?
CTMs with three or more years of CRA or site management experience and a relevant life sciences degree are competitive candidates for sponsorship. CROs and mid-to-large pharma companies sponsor H-1B workers regularly for this role. The main constraint is the annual H-1B lottery, not employer willingness. Australians can sidestep the lottery entirely with the E-3 visa. Browse open roles on Migrate Mate to see which employers are actively sponsoring.
Can I transfer my H-1B to a new CTM employer mid-study?
Yes. H-1B portability allows you to change employers once your new employer files a transfer petition, even before it's approved, as long as your current H-1B was properly approved and you've maintained valid status. For CTMs mid-trial, timing matters since your name may be on regulatory documents. Coordinate with both employers and an immigration attorney before making the move.
What is the prevailing wage requirement for sponsored Clinical Trial Manager jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.
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