Commercial Excellence Manager Jobs in USA with Visa Sponsorship
Commercial Excellence Manager roles attract H-1B sponsorship from large multinationals in consumer goods, pharma, and technology. Most employers require a bachelor's degree in business or a related field, and many treat this as a specialty occupation with strong approval rates. For detailed occupation requirements, see the O*NET profile.
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Work Schedule
Standard (Mon-Fri)
Environmental Conditions
Office
Job Description
As part of the Thermo Fisher Scientific team, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. The Senior Manager, Commercial Excellence will partner with the VP, Commercial and Regional Commercial leaders across the globe to ensure the successful implementation of a best-in-class commercial ecosystem and operating model. You will work collaboratively with various departments to deploy commercial operating models and processes that align with the Clinical Next-Generation Sequencing Division's strategic objectives, driving a continuous improvement in culture across the commercial teams.
Key Responsibilities
- Serve as a strategic thought partner to VP of Commercial of CSD translating regional growth priorities into actionable sales operations strategies that drive revenue acceleration, operational rigor, and predictable execution.
- Enable decision-making for regional sales leaders through proactive insights, delivering forward-looking analytics, performance narratives, and scenario modeling that support territory optimization, pipeline health, and investment prioritization.
- Partner with our COE's and Marketing Teams to implement and deploy process excellence in commercial execution and channel customer engagement.
- Partner with the Sales Training team to ensure they provide training and ongoing support to ensure successful adoption of new commercial excellence tools and establish certified practitioners.
- Drive commercial initiatives across the division to ensure projects meet business objectives and are accomplished on time and within budget.
- Track performance, find opportunities for continuous improvement, and implement changes to enhance the operating model. Maintain detailed documentation of commercial excellence tools and changes made.
- Support the commercial teams in solving critical problems, using problem-solving and kaizen methodology.
- Lead the sales force effectiveness initiatives to ensure global visibility to actionable data for the sales organization.
- Optimize and manage effective and efficient operating mechanisms for the Commercial leadership team to establish a scalable operations platform to ensure aggressive execution, efficiency, profitability, and compliance across the division.
- Launch and lead a pricing committee globally for CSD while developing standard practices, KPI dashboard, and guidelines to be implemented across the regions.
- Serve as a thought partner in commercial excellence tools, supporting the adoption and deployment of Thermo Fisher Scientific tools and demeanor across the regions.
- Willingness to travel 25%-50% domestically and internationally as required.
Qualifications
Education
- Bachelor's degree required with a focus in Business or a related field preferred. MBA degree is preferred.
- Certification as a trainer or facilitator and certified practitioner in lean tools is highly preferred.
Experience
- 12 plus years of relatable experience.
- 4+ years of commercial experience with a consistent track record of driving processes to achieve results required, ideally with experience as a sales representative or sales leader in a regulatory environment within Healthcare, Med Tech, Pharma, or Life Sciences.
- 3+ years confirmed experience with the core tools of visual management, problem solving, and kaizen at a company focused on continuous improvement required.
- Experience with demand forecasting is preferred.
- Extensive experience with Salesforce.com, Seibel, and CRM (funnel management, dashboards) required.
- Strong analytical and problem-solving skills with experience using tools such as MS Excel and Power BI to visualize sales data required. SAP knowledge preferred.
- Demonstrated ability to work cross-functionally in a large and complex organization in a biotech or clinical healthcare industry preferred.
- Excellent interpersonal skills with the ability to navigate a sophisticated, matrix organization, optimally convey new concepts, tools and strategies, and tailor communications according to the audience is required.
- Capacity to navigate ambiguity and uncertainty, consistently demonstrating a growth mindset and resilience in the face of obstacles is required.
- Shown success in driving business impact through continuous improvement and Kaizen initiatives, particularly in commercial organizations and in a fast-changing environment is required.
Compensation
The salary range estimated for this position based in California is $130,000.00-$175,000.00.
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

Work Schedule
Standard (Mon-Fri)
Environmental Conditions
Office
Job Description
As part of the Thermo Fisher Scientific team, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. The Senior Manager, Commercial Excellence will partner with the VP, Commercial and Regional Commercial leaders across the globe to ensure the successful implementation of a best-in-class commercial ecosystem and operating model. You will work collaboratively with various departments to deploy commercial operating models and processes that align with the Clinical Next-Generation Sequencing Division's strategic objectives, driving a continuous improvement in culture across the commercial teams.
Key Responsibilities
- Serve as a strategic thought partner to VP of Commercial of CSD translating regional growth priorities into actionable sales operations strategies that drive revenue acceleration, operational rigor, and predictable execution.
- Enable decision-making for regional sales leaders through proactive insights, delivering forward-looking analytics, performance narratives, and scenario modeling that support territory optimization, pipeline health, and investment prioritization.
- Partner with our COE's and Marketing Teams to implement and deploy process excellence in commercial execution and channel customer engagement.
- Partner with the Sales Training team to ensure they provide training and ongoing support to ensure successful adoption of new commercial excellence tools and establish certified practitioners.
- Drive commercial initiatives across the division to ensure projects meet business objectives and are accomplished on time and within budget.
- Track performance, find opportunities for continuous improvement, and implement changes to enhance the operating model. Maintain detailed documentation of commercial excellence tools and changes made.
- Support the commercial teams in solving critical problems, using problem-solving and kaizen methodology.
- Lead the sales force effectiveness initiatives to ensure global visibility to actionable data for the sales organization.
- Optimize and manage effective and efficient operating mechanisms for the Commercial leadership team to establish a scalable operations platform to ensure aggressive execution, efficiency, profitability, and compliance across the division.
- Launch and lead a pricing committee globally for CSD while developing standard practices, KPI dashboard, and guidelines to be implemented across the regions.
- Serve as a thought partner in commercial excellence tools, supporting the adoption and deployment of Thermo Fisher Scientific tools and demeanor across the regions.
- Willingness to travel 25%-50% domestically and internationally as required.
Qualifications
Education
- Bachelor's degree required with a focus in Business or a related field preferred. MBA degree is preferred.
- Certification as a trainer or facilitator and certified practitioner in lean tools is highly preferred.
Experience
- 12 plus years of relatable experience.
- 4+ years of commercial experience with a consistent track record of driving processes to achieve results required, ideally with experience as a sales representative or sales leader in a regulatory environment within Healthcare, Med Tech, Pharma, or Life Sciences.
- 3+ years confirmed experience with the core tools of visual management, problem solving, and kaizen at a company focused on continuous improvement required.
- Experience with demand forecasting is preferred.
- Extensive experience with Salesforce.com, Seibel, and CRM (funnel management, dashboards) required.
- Strong analytical and problem-solving skills with experience using tools such as MS Excel and Power BI to visualize sales data required. SAP knowledge preferred.
- Demonstrated ability to work cross-functionally in a large and complex organization in a biotech or clinical healthcare industry preferred.
- Excellent interpersonal skills with the ability to navigate a sophisticated, matrix organization, optimally convey new concepts, tools and strategies, and tailor communications according to the audience is required.
- Capacity to navigate ambiguity and uncertainty, consistently demonstrating a growth mindset and resilience in the face of obstacles is required.
- Shown success in driving business impact through continuous improvement and Kaizen initiatives, particularly in commercial organizations and in a fast-changing environment is required.
Compensation
The salary range estimated for this position based in California is $130,000.00-$175,000.00.
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
How to Get Visa Sponsorship as a Commercial Excellence Manager
Target multinational employers with established sponsorship programs
Large consumer goods, pharmaceutical, and technology companies sponsor Commercial Excellence Managers regularly. These employers have dedicated immigration teams, making the H-1B process faster and more predictable than working with smaller firms unfamiliar with sponsorship.
Emphasize the specialized nature of your role
USCIS approvals hinge on proving the job requires a specific bachelor's degree. Frame your work around revenue strategy, commercial analytics, or pricing optimization, disciplines with clear degree requirements, rather than general business operations or management.
Align your degree to the commercial function, not just business broadly
Degrees in business administration, economics, marketing, or finance support this role. If your degree is in an adjacent field, document how your coursework directly supports commercial strategy work to strengthen the specialty occupation argument.
Prepare for the prevailing wage determination early
Your employer files a Labor Condition Application before your H-1B petition. Commercial Excellence roles vary significantly by industry and seniority, so understanding where your offered compensation sits relative to prevailing wage levels helps avoid LCA complications.
Document cross-functional impact in your resume and petition
Commercial Excellence roles often span sales, marketing, and finance. Make your degree-to-role connection explicit in petition support letters. Show how your specialized training directly informs pricing, go-to-market strategy, or commercial capability building.
Ask about cap-exempt opportunities if you're already on OPT or CPT
Universities and qualifying nonprofit research organizations are cap-exempt, meaning they can file H-1B petitions year-round without lottery entry. Some commercial excellence functions exist within these institutions, so they are worth exploring.
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Get Access To All JobsFrequently Asked Questions
Do Commercial Excellence Manager roles qualify for H-1B sponsorship?
Yes, most do. The role typically requires a bachelor's degree in business, economics, marketing, or finance, which satisfies the specialty occupation standard. Employers in consumer goods, pharma, and technology sponsor this title regularly. Approval rates are strong when the petition clearly documents the degree-to-role connection and the employer has prior sponsorship experience.
What degree do I need for an employer to sponsor me as a Commercial Excellence Manager?
A bachelor's degree in business administration, economics, marketing, finance, or a closely related field is standard. Some employers also accept degrees in data science or operations management if the role has a strong analytics component. The key is that your degree maps directly to the commercial discipline the job requires, not just business broadly.
Which industries are most likely to sponsor this role?
Consumer packaged goods companies, pharmaceutical and life sciences firms, and enterprise technology companies sponsor Commercial Excellence Managers most frequently. These industries have mature commercial functions and established immigration programs. You can browse open roles with visa sponsorship on Migrate Mate, where listings are filtered specifically for employers willing to sponsor.
Can I transfer my H-1B to a new Commercial Excellence Manager role?
Yes. H-1B portability allows you to change employers once your transfer petition is filed, without waiting for approval, as long as you have been in valid H-1B status for at least 180 days. The new employer files a fresh I-129. Because Commercial Excellence is a recognizable specialty occupation, transfers are generally straightforward when both roles share similar duties and degree requirements.
Is Commercial Excellence Manager a common target for H-1B RFEs or denials?
It can attract a Request for Evidence if the petition describes duties that sound like general management rather than a specialized commercial function. USCIS looks for evidence that a specific degree is both required and used in daily work. Petitions that clearly articulate revenue strategy, commercial capability, or pricing analytics disciplines, backed by the job description and a strong support letter, significantly reduce RFE risk.
What is the prevailing wage requirement for sponsored Commercial Excellence Manager jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.
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