Demand Generation Manager Jobs in USA with Visa Sponsorship
Demand Generation Managers typically qualify for H-1B visa or O-1 visa sponsorship, as the role meets specialty occupation requirements through its requirement for a bachelor's degree in marketing, business, or a related field. Employers in tech and SaaS sponsor this role regularly. For detailed occupation requirements, see the O*NET profile.
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Get Access To All JobsINTRODUCTION
Sapient is a fast-growing early-stage biotech company headquartered in San Diego, CA. Our focus is on delivering multi-omics services to accelerate drug development and transform personalized medicine. Combining state-of-the-art mass spectrometry technology with advanced biocomputational services and multifaceted human health data, we enable biomarker discovery at unprecedented speed and scale to provide a deeper understanding of human biology and effectively align biological targets, patients, and drug therapies. We are a highly collaborative team of passionate scientists, clinicians, and engineers with expertise in various disciplines, committed to making innovations with scientific rigor. Ultimately, our platform technology enhances the precision and efficacy of treatments, touching and enhancing countless lives.
ABOUT THE ROLE
We are seeking a motivated and detail-oriented AI Demand Generation & Outreach Specialist to join our growing commercial team. This position offers an excellent opportunity to develop diverse skills in marketing and sales development within the life sciences industry as part of an innovative company “going beyond the genome” to advance precision medicine and ultimately improve patients’ lives. As a rapidly growing start-up, we value team members who can function highly in a fast-paced environment and who think and work well independently. Exceptional opportunity to work closely with top commercial and scientific personnel with high opportunity for career development and growth. This position is remote.
JOB DESCRIPTION
- Build and run AI-assisted outbound campaigns that generate qualified meetings for the CSO and business development team across Sapient's discovery proteomics, metabolomics, targeted protein assay and FFPE tumor proteomics services.
- Map each service line to the right scientific personas and develop clear, specific messaging that earns replies from translational medicine, biomarker, clinical development and target discovery leaders at pharma and biotech companies.
- Build targeted prospect lists for conferences and campaigns from speaker programs, exhibitor lists, attendee data and professional networks, screening each list against CRM history and do-not-contact lists.
- Write and edit outreach copy, web content and case studies, partnering with the science team to ensure every technical claim is accurate and supported.
- Quality-control every campaign before launch and manage sequences, schedules, sender mailboxes and test sends in our sending platform.
- Own campaign responses: qualify replies, answer straightforward questions, book meetings and follow through until each conversation lands.
- Improve how Sapient is found online through search optimization, structured and machine-readable content, and generative engine optimization so AI assistants surface and accurately describe our services.
- Set up tracking and attribution before launch, publish the monthly outreach performance dashboard and maintain the campaign calendar.
- Test subject lines, messaging angles, sequence length and send timing, and turn results into recommendations on who and how we target next.
- Support conference and trade show presence and event follow-up campaigns, keeping brand messaging consistent across email, decks and web.
- Maintain accurate records of contacts, responses and qualified leads within our CRM system (Dynamics).
- Contribute improvements to the outreach pipeline, including script, prompt and documentation updates, and document lessons learned as repeatable practices.
REQUIREMENTS
- BS or BA in a life science field (biology, biochemistry, bioengineering or similar), or equivalent practical exposure to the life science industry.
- 1 to 3 years' experience in marketing, sales development, communications or another commercial role in life sciences.
- Fluent, daily use of AI assistants such as Claude or ChatGPT, with the discipline to verify output against the source.
- Comfortable with technology, including running scripts, editing CSV and configuration files, and using git and GitHub. Formal software engineering experience is not required.
- Working knowledge of how drug development is organized and what translational and biomarker teams care about.
- Strong marketing and commercial instinct: able to judge why a message lands and whether a prospect has a real need, budget and reason to engage.
- Clear, concise writing and confidence communicating with senior scientists by email and phone.
- Highly detail oriented with strong follow-through; checks rather than assumes.
- Resilient, self-motivated and comfortable with ambiguity in a fast-paced environment.
- Sound judgment handling confidential prospect data, CRM exports and executive sending accounts.
- Spreadsheet fluency (Excel or Google Sheets) and working knowledge of SEO fundamentals. Interest in generative engine optimization is a plus.
- Experience with campaign or prospecting platforms (e.g., HubSpot, Smartlead, Apollo, Clay, LinkedIn Sales Navigator), analytics tools, a CMS, a CRM or Python is preferred but not required.
POSITION DETAILS
- Position Type: Full-time.
- Compensation: $70,000 to $95,000 base depending on experience, plus a $10,000 variable component tied to qualified meetings created.
Sapient is an equal opportunity employer. We value diversity, inclusivity and belonging of all people from different cultures and socioeconomic backgrounds. We do not discriminate based on race, ethnicity, gender, age, sex, disability or any other secondary biases.
The pay range for this role is:
70,000 - 95,000 USD per year (Remote (United States))
INTRODUCTION
Sapient is a fast-growing early-stage biotech company headquartered in San Diego, CA. Our focus is on delivering multi-omics services to accelerate drug development and transform personalized medicine. Combining state-of-the-art mass spectrometry technology with advanced biocomputational services and multifaceted human health data, we enable biomarker discovery at unprecedented speed and scale to provide a deeper understanding of human biology and effectively align biological targets, patients, and drug therapies. We are a highly collaborative team of passionate scientists, clinicians, and engineers with expertise in various disciplines, committed to making innovations with scientific rigor. Ultimately, our platform technology enhances the precision and efficacy of treatments, touching and enhancing countless lives.
ABOUT THE ROLE
We are seeking a motivated and detail-oriented AI Demand Generation & Outreach Specialist to join our growing commercial team. This position offers an excellent opportunity to develop diverse skills in marketing and sales development within the life sciences industry as part of an innovative company “going beyond the genome” to advance precision medicine and ultimately improve patients’ lives. As a rapidly growing start-up, we value team members who can function highly in a fast-paced environment and who think and work well independently. Exceptional opportunity to work closely with top commercial and scientific personnel with high opportunity for career development and growth. This position is remote.
JOB DESCRIPTION
- Build and run AI-assisted outbound campaigns that generate qualified meetings for the CSO and business development team across Sapient's discovery proteomics, metabolomics, targeted protein assay and FFPE tumor proteomics services.
- Map each service line to the right scientific personas and develop clear, specific messaging that earns replies from translational medicine, biomarker, clinical development and target discovery leaders at pharma and biotech companies.
- Build targeted prospect lists for conferences and campaigns from speaker programs, exhibitor lists, attendee data and professional networks, screening each list against CRM history and do-not-contact lists.
- Write and edit outreach copy, web content and case studies, partnering with the science team to ensure every technical claim is accurate and supported.
- Quality-control every campaign before launch and manage sequences, schedules, sender mailboxes and test sends in our sending platform.
- Own campaign responses: qualify replies, answer straightforward questions, book meetings and follow through until each conversation lands.
- Improve how Sapient is found online through search optimization, structured and machine-readable content, and generative engine optimization so AI assistants surface and accurately describe our services.
- Set up tracking and attribution before launch, publish the monthly outreach performance dashboard and maintain the campaign calendar.
- Test subject lines, messaging angles, sequence length and send timing, and turn results into recommendations on who and how we target next.
- Support conference and trade show presence and event follow-up campaigns, keeping brand messaging consistent across email, decks and web.
- Maintain accurate records of contacts, responses and qualified leads within our CRM system (Dynamics).
- Contribute improvements to the outreach pipeline, including script, prompt and documentation updates, and document lessons learned as repeatable practices.
REQUIREMENTS
- BS or BA in a life science field (biology, biochemistry, bioengineering or similar), or equivalent practical exposure to the life science industry.
- 1 to 3 years' experience in marketing, sales development, communications or another commercial role in life sciences.
- Fluent, daily use of AI assistants such as Claude or ChatGPT, with the discipline to verify output against the source.
- Comfortable with technology, including running scripts, editing CSV and configuration files, and using git and GitHub. Formal software engineering experience is not required.
- Working knowledge of how drug development is organized and what translational and biomarker teams care about.
- Strong marketing and commercial instinct: able to judge why a message lands and whether a prospect has a real need, budget and reason to engage.
- Clear, concise writing and confidence communicating with senior scientists by email and phone.
- Highly detail oriented with strong follow-through; checks rather than assumes.
- Resilient, self-motivated and comfortable with ambiguity in a fast-paced environment.
- Sound judgment handling confidential prospect data, CRM exports and executive sending accounts.
- Spreadsheet fluency (Excel or Google Sheets) and working knowledge of SEO fundamentals. Interest in generative engine optimization is a plus.
- Experience with campaign or prospecting platforms (e.g., HubSpot, Smartlead, Apollo, Clay, LinkedIn Sales Navigator), analytics tools, a CMS, a CRM or Python is preferred but not required.
POSITION DETAILS
- Position Type: Full-time.
- Compensation: $70,000 to $95,000 base depending on experience, plus a $10,000 variable component tied to qualified meetings created.
Sapient is an equal opportunity employer. We value diversity, inclusivity and belonging of all people from different cultures and socioeconomic backgrounds. We do not discriminate based on race, ethnicity, gender, age, sex, disability or any other secondary biases.
The pay range for this role is:
70,000 - 95,000 USD per year (Remote (United States))
See all 1,691+ Demand Generation Manager Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Demand Generation Manager roles.
Get Access To All JobsTips for Finding Visa Sponsorship as a Demand Generation Manager
Target companies with an H-1B filing history
SaaS, fintech, and enterprise tech companies file H-1B petitions for Demand Generation Managers consistently. Searching OFLC disclosure data by job title confirms which employers have sponsored this role before, reducing the risk of approaching companies that won't.
Frame your degree as a specialty occupation match
USCIS requires a specific bachelor's degree for H-1B eligibility. Marketing, business administration, communications, or data analytics degrees map cleanly to this role. A misaligned degree raises a Request for Evidence, so address the connection explicitly in your application materials.
Quantify pipeline and revenue impact in your resume
Sponsoring employers want proof that you generate measurable business outcomes. Highlight metrics like qualified pipeline generated, cost per lead, and marketing-attributed revenue. Concrete numbers differentiate you from candidates with identical titles but weaker evidence of impact.
Prepare your employer for the LCA process
Many smaller companies are unfamiliar with the Labor Condition Application requirement. Explaining that the employer files the LCA with the Department of Labor before the visa petition, and that it confirms prevailing wage compliance, removes a common blocker for first-time sponsors.
Australians should prioritize the E-3 pathway
The E-3 visa has no lottery, processes within weeks, and renews indefinitely. For Australian Demand Generation Managers, it is a faster and more predictable path than H-1B. Employers unfamiliar with the E-3 often agree once they understand there is no cap risk.
Demonstrate cross-functional collaboration in interviews
Demand Generation Managers work closely with sales, product, and analytics teams. Employers evaluating whether to sponsor often weigh role criticality heavily. Showing deep cross-functional ownership signals that the position is specialized enough to justify the sponsorship investment and petition cost.
Frequently Asked Questions
Does a Demand Generation Manager role qualify for H-1B sponsorship?
Yes, Demand Generation Manager typically qualifies as a specialty occupation under H-1B visa because the role normally requires a bachelor's degree in marketing, business, communications, or a related field. USCIS has approved this title under H-1B petitions, though a Request for Evidence is more likely if the job description is broad or if the employer cannot demonstrate that a specific degree is always required for the position.
What degree do I need for a sponsored Demand Generation Manager position?
Most H-1B petitions for this role are supported by a bachelor's degree in marketing, business administration, communications, data analytics, or a closely related field. A general management or unrelated degree can complicate the specialty occupation argument. If your degree is not an exact match, three years of specialized work experience can substitute for one year of education under USCIS equivalency rules.
Which types of employers sponsor Demand Generation Managers?
SaaS companies, fintech firms, and enterprise technology companies are the most consistent sponsors for this role, as they typically have established immigration programs and recurring demand for pipeline-focused marketers. Mid-stage startups with Series B funding and beyond also sponsor regularly. You can browse verified sponsoring employers hiring for this role directly on Migrate Mate.
How does the H-1B lottery affect my chances as a Demand Generation Manager?
The H-1B regular cap includes an 85,000-slot annual allocation, of which 20,000 are reserved for U.S. master's degree holders. In recent years USCIS has received over 400,000 registrations, resulting in a selection rate around 20 to 25 percent. Australian citizens can bypass the lottery entirely through the E-3 visa, which has a 10,500 annual cap that has never been fully utilized.
Can a Demand Generation Manager role support an O-1A petition?
It depends on your career record. The O-1A requires evidence of extraordinary ability across criteria such as awards, high salary relative to peers, critical roles at distinguished organizations, or published contributions in the field. Senior demand generation professionals who have led large-scale campaigns, spoken at industry conferences, or been recognized by professional organizations may meet the threshold. It is not a standard path for early-career candidates.
What is the prevailing wage requirement for sponsored Demand Generation Manager jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.