Advanced Practice Registered Nurse Aprn Jobs

Advanced Practice Registered Nurse Aprn jobs are open across hospitals, outpatient clinics, and community health settings, at every level from new-graduate to lead clinician, with common specializations in family practice, acute care, and psychiatric-mental health. Find a role that fits from the openings below and apply directly.

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Overview

Open roles13+
Top stateIllinois
Top cityHouston, TX
Work type85% On-site
Top industryHealthcare

Showing 5 of 13+ Advanced Practice Registered Nurse Aprn jobs

MD Anderson Cancer Center
Advanced Practice Registered Nurse (APRN or PA) General Oncology
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MD Anderson Cancer Center
Added 5d ago
Advanced Practice Registered Nurse (APRN or PA) General Oncology
MD Anderson Cancer Center
Houston, Texas
Nursing
Healthcare Administration
Patient Services & Wellbeing
$118k - $177k/yr
Hybrid
Master's
10,000+

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MD Anderson Cancer Center
Advanced Practice Registered Nurse (APRN or PA) General Oncology
We won't show you this job again
MD Anderson Cancer Center
Added 2w ago
Advanced Practice Registered Nurse (APRN or PA) General Oncology
MD Anderson Cancer Center
Houston, Texas
Nursing
Healthcare Administration
Patient Services & Wellbeing
$118k - $177k/yr
Hybrid
Master's
10,000+

Have you applied for this role?

Hospital Sisters Health System
Advanced Practice Registered Nurse (APRN) / Physician Assistant (PA)
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Hospital Sisters Health System
Added 2w ago
Advanced Practice Registered Nurse (APRN) / Physician Assistant (PA)
Hospital Sisters Health System
O'Fallon, Illinois
Nursing
Healthcare Administration
Patient Services & Wellbeing
$63.69/hr
On-Site
Master's

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Hospital Sisters Health System
Advanced Practice Registered Nurse (APRN) / Physician Assistant (PA)
We won't show you this job again
Hospital Sisters Health System
Added 2w ago
Advanced Practice Registered Nurse (APRN) / Physician Assistant (PA)
Hospital Sisters Health System
Decatur, Illinois
Nursing
Healthcare Administration
Patient Services & Wellbeing
$132k/yr
On-Site
Master's

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Hospital Sisters Health System
Advanced Practice Registered Nurse (APRN) / Physician Assistant (PA)
We won't show you this job again
Hospital Sisters Health System
Added 2w ago
Advanced Practice Registered Nurse (APRN) / Physician Assistant (PA)
Hospital Sisters Health System
O'Fallon, Illinois
Nursing
Healthcare Administration
Patient Services & Wellbeing
$128k/yr
On-Site
Master's

Have you applied for this role?

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Advanced Practice Registered Nurse Aprn Job Market

A snapshot from current openings nationwide, updated as new roles post.

Who's Hiring

  • Hospital Sisters Health System
    Hospital Sisters Health System3
  • MD Anderson Cancer Center
    MD Anderson Cancer Center3
  • Hshs Medical
    Hshs Medical2
  • Morehouse School of Medicine
    Morehouse School of Medicine1
  • Norton Healthcare
    Norton Healthcare1

Top Industries Hiring

  • Healthcare & Medical Services8
  • Education4
  • Government & Public Sector1
  • Transportation & Logistics1

What Employers Look For

The qualifications that appear most often in advanced practice registered nurse aprn jobs.

  • Active APRN license and national certification from ANCC or AANP
  • Master of Science in Nursing or Doctor of Nursing Practice degree
  • Minimum two years of clinical experience in a relevant specialty area
  • Current DEA registration and state prescriptive authority for controlled substances
  • BLS and ACLS certification current at time of hire
  • Experience with electronic health record systems such as Epic or Cerner

Tips for Your Advanced Practice Registered Nurse Aprn Job Search

Tailor your resume to your specialty

Generic nursing resumes get passed over fast. Highlight your specific APRN population focus, prescriptive authority state, and clinical hours by setting. Recruiters screening for a family nurse practitioner read differently than those hiring for an acute care NP.

Verify your license before you apply

Many postings require a compact state license or a specific state's APRN authorization before an offer is extended. Confirm your licensure status and any pending endorsements match the state listed in the opening before you submit an application.

Apply early to roles that fit

Migrate Mate lists advanced practice registered nurse aprn openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Highlight DEA registration if applicable

Roles with full prescriptive authority often screen for active DEA registration separately from your APRN license. List it explicitly on your resume and note your Schedule II-V authority. Leaving it out can disqualify you even when you're otherwise a strong fit.

Prepare protocol and scope questions for interviews

Interviewers at physician-led practices often probe how you navigate collaborative agreement requirements. Know your state's supervision rules cold and come ready to describe a specific case where you escalated appropriately within a collaborative framework.

Negotiate your signing bonus and CME allowance

APRN offers frequently include continuing medical education allowances and malpractice tail coverage that are negotiable but rarely advertised. Ask for the full benefits breakdown before you accept, and compare CME amounts and license reimbursement across competing offers.

Advanced Practice Registered Nurse Aprn Jobs: Frequently Asked Questions

Which companies are hiring the most advanced practice registered nurse aprns?

The companies hiring the most advanced practice registered nurse aprns right now include Hospital Sisters Health System, MD Anderson Cancer Center, and Hshs Medical, with the largest share of openings in Illinois, Texas, and Kentucky, based on current listings on Migrate Mate as of June 2026. Large health systems and federally qualified health centers consistently post high volumes of APRN roles across primary care and specialty settings.

How many advanced practice registered nurse aprn jobs are remote?

About 15% of advanced practice registered nurse aprn openings are fully remote or hybrid as of June 2026, with telehealth platforms and behavioral health practices accounting for the largest share of those remote positions. Acute care, procedural, and hospital-based APRN roles remain almost entirely in person.

How do you become an advanced practice registered nurse aprn?

You start by earning a registered nurse license, then complete a graduate-level nursing program at the master's or doctoral level with a defined population focus such as family, adult-gerontology, or psychiatric-mental health. After graduation you sit for a national certification exam through ANCC or AANP, then apply for state APRN licensure and, where required, prescriptive authority.

Can you get hired as an advanced practice registered nurse aprn with limited experience?

New-graduate APRNs do get hired, but competition is stiff for the most independent roles. Targeting residency or fellowship programs designed specifically for new APRNs, applying to federally qualified health centers that have structured onboarding, and emphasizing your graduate clinical hours in your application all meaningfully improve your chances without fabricating experience you don't have.

What does the advanced practice registered nurse aprn interview process look like?

Most APRN hiring processes include an initial phone screen with a recruiter, followed by a clinical panel interview with a medical director or supervising physician and a nurse leader. You're likely to face scenario-based questions about patient management and prescribing decisions. Some employers add a credentialing review or reference check before extending an offer, which can add time to the process.

Where can I find and apply to advanced practice registered nurse aprn jobs?

You can find and apply to advanced practice registered nurse aprn jobs on Migrate Mate, which lists current openings from across the United States in one place. Search the listings for roles that match your specialty, state licensure, and practice setting, then apply directly to each opening that fits.

See All Advanced Practice Registered Nurse Aprn Jobs

Jump back to the full list of openings and apply to any advanced practice registered nurse aprn role that fits.

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