Advanced Practice Registered Nurse Aprn Jobs in Illinois
Advanced Practice Registered Nurse Aprn jobs in Illinois are among the most active in the Midwest, with strong demand from hospital systems, federally qualified health centers, and multispecialty outpatient groups at every level from new graduate to senior clinician. Chicago, Peoria, and Rockford anchor the largest hiring volumes, where established employers like Northwestern Medicine, Advocate Health Care, and OSF HealthCare consistently staff advanced practice roles. The most in-demand specialties include acute care, family practice, and psychiatric mental health. Find a role that fits below and apply directly.
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HSHS Medical Group is seeking a Board-Certified/Board-Eligible Nurse Practitioner or Physician Assistant to join our growing Gastroenterology team in O’Fallon, Illinois. This role primarily focuses on outpatient clinic responsibilities with occasional hospital rounding as needed.
You’ll be part of a well-established and expanding practice within the Hospital Sisters Health System, working closely with a multidisciplinary team to deliver high-quality patient care.
Practice Highlights:
- Well established, growing practice.
- No holidays or weekends
- No required call
- EPIC EMR
- Clinics are within the hospitals, providing access to all imaging, labs, scans, etc. needed.
- Ample training time provided with GI team.
Position Requirements:
- Unrestricted Illinois license and DEA prior to start
- Board Certified
- 2+ years of provider work experience is strongly preferred.
- Experience in GI is preferred, but experience in other specialties will also be
Compensation & Benefits Package:
- Base Salary: $128,153 With Bonus Earning Potential
- Paid time off with holidays accrued bi-weekly
- CME reimbursement + days available per fiscal year
- Opportunities to earn productivity and patient outcome/patient satisfaction
- Sign on bonus and relocation assistance both available
Core Function: Provider
Education Qualifications
- Master’s degree in Nursing is required.
- Bachelor’s Degree in Nursing PLUS 5 years relevant experience may be considered in lieu of degree.
- Doctoral degree in Nursing is preferred.
- Experience in management of patients across the care continuum preferred.
- Licensed in the state of practice as Advanced Practice Registered Nurse is required.
- Wisconsin Department of Safety and Professional Services (WDSPS) or
- Illinois Department of Financial and Professional Regulation (IDFPR)
- Basic Life Support (BLS) certification is required.
- Board certification from the National Certification Corporation is preferred.
- Controlled Substance license in state of practice is preferred.
- Federal DEA license is preferred.
- Neonatal Resuscitation Program (NRP) certification is preferred.
Throughout communities in Illinois and Wisconsin, 13 hospitals, numerous community-based health centers and clinics, our 13,000+ colleagues have built a culture based on our solid core values of respect, care, competence, and joy. These are the ideals we believe in, work by, and live each day.
Built upon more than 145 years of service to the communities we serve, we now look to the future and our place in it as a healthcare system that strives to continually improve processes, procedures, and outcomes with the latest and most advanced technologies and treatments.
Regardless of how far our passion for excellence carries us, our focus will always remain on the most important person in our entire organization: The patient.
HSHS requires COVID-19 vaccines or an approved medical or religious exemption for all colleagues.
HSHS and affiliates is an Equal Opportunity Employer (EOE).
HSHS is proud to be an equal opportunity workplace dedicated to pursuing and hiring a diverse workforce.
Benefits: HSHS provides a benefits package designed to support the overall well-being of our colleagues including their physical, emotional, financial, spiritual, and work health. Colleagues budgeted to work at least 32 hours per pay period are eligible for HSHS benefits.
- Comprehensive and affordable health coverage includes medical, prescription, dental and vision coverage for full-time and part-time colleagues.
- Retirement benefits including HSHS contributions.
- Education Assistance benefits include up to $5,250 of educational assistance each calendar year and tuition discounts to select colleges with no waiting period
- Adoption Assistance provides financial support up to $7,500 for colleagues growing their families through adoption to reimburse application and legal fees, transportation, and more!
- Other benefits include: Wellness program with incentives, employer-paid life insurance and short-term and long-term disability coverage, flexible spending accounts, employee assistance program, ID theft coverage, colleague rewards and recognition program, discount program, and more!
A successful candidate's actual pay rate will be based on several factors including relevant experience, skills, training, certifications and education.
Notice Regarding Potential Use of Artificial Intelligence in the Hiring Process
Hospital Sisters may use automated tools, including artificial intelligence or machine-learning technologies, to assist with certain administrative aspects of the recruitment process. These tools may help our recruiting team organize applications, search for resumes, identify qualifications reflected in application materials, and facilitate communications or scheduling with applicants.
Information used by these tools may include materials you provide during the application process, such as your resume, work history, education, qualifications, and responses to application questions.
These tools are used only to support our recruiting process. Hiring decisions are made by HSHS personnel, and automated tools do not make employment decisions on behalf of HSHS.
Applicants who have questions about this notice or who require a reasonable accommodation or alternative evaluation method may contact HSHS Human Resources at Contact@hshs.org
See All 17 Advanced Practice Registered Nurse Aprn Jobs in Illinois
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Find JobsAdvanced Practice Registered Nurse Aprn Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Advanced Practice Registered Nurse Aprn Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
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What Illinois Employers Look For
The qualifications that appear most often in advanced practice registered nurse aprn jobs across Illinois.
- Active Illinois advanced practice registered nurse license issued by the Illinois Department of Financial and Professional Regulation
- Current national certification from ANCC, AANP, or an equivalent accredited certifying body
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- Active, unrestricted Illinois collaborating physician agreement where required by practice setting
- Current DEA registration for schedules II through V where prescriptive authority is exercised
- Minimum one to three years of clinical experience in a relevant specialty or patient population
Advanced Practice Registered Nurse Aprn Jobs in Illinois: Frequently Asked Questions
How do you become a advanced practice registered nurse aprn in Illinois?
You must earn a graduate nursing degree, complete national certification in your specialty, and obtain an advanced practice registered nurse license through the Illinois Department of Financial and Professional Regulation. The IDPR issues APRN licenses in four roles: nurse practitioner, certified nurse midwife, certified registered nurse anesthetist, and clinical nurse specialist. You will also need an active registered nurse license in Illinois before the APRN credential is granted.
How much do advanced practice registered nurse aprns make in Illinois?
Advanced practice registered nurse aprns in Illinois earn a median of about $130,680 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $102,440 for the lowest 10% to over $161,470 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire advanced practice registered nurse aprns in Illinois?
Employers hiring advanced practice registered nurse aprns in Illinois right now include Advocate Aurora Health, Endeavor Health, and Lake County, IL, based on current listings on Migrate Mate as of October 2026. Illinois's density of large academic medical centers, regional health systems, and community health networks means consistent openings across a wide range of specialties and practice settings statewide.
Which Illinois cities have the most advanced practice registered nurse aprn jobs?
Chicago, Oak Lawn, and Park Ridge have the most advanced practice registered nurse aprn openings in Illinois. Chicago drives the highest volume by far because of its concentration of academic medical centers, large multispecialty groups, and federally qualified health centers, while Peoria and Rockford support strong regional markets anchored by OSF HealthCare and Mercyhealth respectively.
Are there remote advanced practice registered nurse aprn jobs in Illinois?
Yes, but they're rare. Advanced practice registered nurse aprn work is fundamentally hands-on, and most roles require direct patient contact in a clinic, hospital, or home setting. About 50% of advanced practice registered nurse aprn openings tied to Illinois are remote or hybrid as of October 2026, and those positions are concentrated in telehealth urgent care and behavioral health, where asynchronous or video-based care is clinically appropriate.
How can I get hired as a advanced practice registered nurse aprn in Illinois with little or no experience?
The most realistic entry path is a new-graduate nurse practitioner residency or fellowship, and Northwestern Medicine, Advocate Health Care, and the University of Illinois Health all run structured programs designed for clinicians without post-certification experience. Candidates who transition from roles as registered nurses, nurse case managers, or clinical nurse specialists have the strongest advantage because of their existing patient care foundation. Holding your Illinois APRN license, a current BLS and ACLS certification, and a letter of collaboration secured before you apply meaningfully shortens the hiring timeline.
Where can I find and apply to advanced practice registered nurse aprn jobs in Illinois?
You can find and apply to advanced practice registered nurse aprn jobs in Illinois on Migrate Mate, which lists current Illinois openings across hospital systems, outpatient groups, and community health settings. Find the roles that fit your specialty and experience and apply directly from the listing.
See All 17 Advanced Practice Registered Nurse Aprn Jobs in Illinois
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