Chief Of Staff Jobs in Massachusetts

Chief Of Staff jobs in Massachusetts are in strong demand, concentrated in technology, life sciences, financial services, and higher education, with openings at every level from early-career chiefs supporting founding teams to senior chiefs embedded with C-suite executives at established enterprises. Boston, Cambridge, and Waltham are the primary hiring centers, where organizations like Massachusetts General Hospital, Fidelity Investments, and HubSpot regularly bring on chiefs of staff to drive operational alignment and strategic execution. The most sought-after specialties in Massachusetts listings include technology operations, healthcare strategy, and venture-backed startup leadership. Find a role that fits below and apply directly.

Find Chief Of Staff Jobs

Overview

Open roles25
Top employerVetcor
Top cityBoston, MA
Cities hiring9
Work type58% Hybrid
Top industryTechnology

Showing 5 of 25+ Chief Of Staff jobs

Vetcor
Chief of Staff Veterinarian - Burlington, MA
We won't show you this job again
Vetcor
Added 2d ago
Chief of Staff Veterinarian - Burlington, MA
Vetcor
Burlington, Massachusetts
Healthcare Administration
Patient Services & Wellbeing
Public Health
$165k - $180k/yr
5,001-10,000

Have you applied for this role?

Vetcor
Chief of Staff - Ashland, MA
We won't show you this job again
Vetcor
Added 2d ago
Chief of Staff - Ashland, MA
Vetcor
Ashland, Massachusetts
Healthcare Administration
Patient Services & Wellbeing
Public Health
$180k - $220k/yr
5,001-10,000

Have you applied for this role?

Autodesk
Chief of Staff
We won't show you this job again
Autodesk
Added 1w ago
Chief of Staff
Autodesk
Massachusetts
Business Operations
Compensation & Benefits
Human Resources (HR) — Generalist
$124k - $223k/yr
Remote (US)
Bachelor's degree in communications
10,000+

Have you applied for this role?

Boston Medical Center
Chief of Staff, System Pharmacy
We won't show you this job again
Boston Medical Center
Added 1w ago
Chief of Staff, System Pharmacy
Boston Medical Center
Boston, Massachusetts
Business Operations
Compensation & Benefits
Human Resources (HR) — Generalist
$141k - $204k/yr
Bachelor's degree in finance
5,001-10,000

Have you applied for this role?

UMass Memorial Health
Senior Executive Assistant, Chief of Staff Office and CEO Office
We won't show you this job again
UMass Memorial Health
Added 1w ago
Senior Executive Assistant, Chief of Staff Office and CEO Office
UMass Memorial Health
Worcester, Massachusetts
Executive Leadership & C-Suite
Program Management
Project Management
$29.81 - $53.67/hr
Associate's degree
10,000+

Have you applied for this role?

See All 25 Chief Of Staff Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Chief Of Staff Jobs

Chief Of Staff Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Boston
11 jobs
Cambridge
5 jobs
Burlington
2 jobs
Ashland
1 job
Waltham
1 job
Lexington
1 job
Worcester
1 job
Somerville
1 job
North Adams
1 job

Chief Of Staff Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

Vetcor
Vetcor2 open roles
TetraScience
TetraScience2 open roles
Lila Sciences
Lila Sciences2 open roles

Top Industries Hiring

  • Technology & Software
  • Biotechnology & Pharmaceuticals

What Massachusetts Employers Look For

The qualifications that appear most often in chief of staff jobs across Massachusetts.

  • Bachelor's degree in business, public policy, or a related field required
  • Five or more years of experience in operations, strategy, or executive support roles
  • Demonstrated ability to manage cross-functional projects and senior stakeholder relationships
  • Strong written and verbal communication skills for board-level and executive audiences
  • Experience in life sciences, technology, or financial services preferred for Massachusetts roles
  • Proficiency with project management tools and comfort working in fast-moving organizational environments

Chief Of Staff Jobs in Massachusetts: Frequently Asked Questions

How do you become a chief of staff in Massachusetts?

There is no state-issued license or certification required to work as a chief of staff in Massachusetts. Most employers look for a bachelor's degree in business, public policy, or a related field, with a graduate degree increasingly common at larger institutions. The typical path runs through roles in strategy, operations, or executive coordination, often within Massachusetts's dominant sectors of life sciences, technology, or financial services, before stepping into a chief of staff position.

Which companies hire chief of staffs in Massachusetts?

Employers hiring chief of staffs in Massachusetts right now include Vetcor, TetraScience, and Lila Sciences, based on current listings on Migrate Mate as of September 2026. Massachusetts's concentration of venture-backed startups, major hospital systems, and global financial firms means openings appear across a wide range of organization sizes and industries throughout the year.

Which Massachusetts cities have the most chief of staff jobs?

Boston, Cambridge, and Burlington are the Massachusetts cities with the most chief of staff openings. Boston anchors the market because it is home to major hospital systems, asset management firms, and a dense cluster of technology companies, while Cambridge draws demand from life sciences and university-affiliated organizations, and Waltham and the Route 128 corridor add volume from established technology and professional services employers.

Are there remote chief of staff jobs in Massachusetts?

Yes, but they are less common than in fully desk-based roles, since most chiefs of staff are expected to be present for executive meetings, board interactions, and operational decisions. About 75% of chief of staff openings tied to Massachusetts are remote or hybrid as of September 2026, with hybrid arrangements more prevalent than fully remote. The strategic planning and project coordination parts of the role are most likely to be performed off-site.

How can I get hired as a chief of staff in Massachusetts with little or no experience?

The most realistic entry path is through a chief of staff associate or junior chief of staff program, which organizations including major Boston-area hospital networks and venture-backed technology companies use to develop early-career candidates. Roles such as executive coordinator, strategy analyst, or operations associate at Massachusetts employers in life sciences or financial services are the most common lateral moves into a first chief of staff position. A graduate degree in business or public policy from one of Massachusetts's universities strengthens a candidate's profile considerably.

Where can I find and apply to chief of staff jobs in Massachusetts?

You can find and apply to chief of staff jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings across industries and experience levels. Search the listings for roles that match your background and apply directly to the ones that fit.

See All 25 Chief Of Staff Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Chief Of Staff Jobs