Chief Of Staff Jobs in Massachusetts

Chief Of Staff jobs in Massachusetts are in strong demand, concentrated in technology, life sciences, financial services, and higher education, with openings at every level from early-career chiefs supporting founding teams to senior chiefs embedded with C-suite executives at established enterprises. Boston, Cambridge, and Waltham are the primary hiring centers, where organizations like Massachusetts General Hospital, Fidelity Investments, and HubSpot regularly bring on chiefs of staff to drive operational alignment and strategic execution. The most sought-after specialties in Massachusetts listings include technology operations, healthcare strategy, and venture-backed startup leadership. Find a role that fits below and apply directly.

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Overview

Open roles20
Top employerTetraScience
Top cityBoston, MA
Cities hiring6
Work type90% Hybrid
Top industryTechnology

Showing 5 of 20+ Chief Of Staff jobs

Counsel & Chief of Staff
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Added 4d ago
Counsel & Chief of Staff
Harvard University
Cambridge, Massachusetts
Biotech & Life Sciences
Clinical Trials & Medical Research
Research & Academia
Hybrid
1,001-5,000

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Staff Physician, Chief Health Office
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Added 5d ago
Staff Physician, Chief Health Office
Boston University
Boston, Massachusetts
Biotech & Life Sciences
Clinical Trials
Healthcare Administration
10,000+

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Chief of Staff
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Added 1w ago
Chief of Staff
Reframe Systems
Billerica, Massachusetts
Brand Marketing
Growth Marketing
Marketing

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Chief of Staff to the CEO
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Added 1w ago
Chief of Staff to the CEO
ServiceNet
Northampton, Massachusetts
Program Management
Project & Program Management
Project Management
$60k - $80k/yr
Bachelor's degree in social work
1,001-5,000

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Chief of Staff - Revenue
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Added 1w ago
Chief of Staff - Revenue
Nexthink
Boston, Massachusetts
Business Operations
Revenue Operations & Enablement
Sales
$140k - $1900k/yr
Hybrid
501-1,000

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See All 20 Chief Of Staff Jobs in Massachusetts

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Chief Of Staff Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Boston
13 jobs
Cambridge
3 jobs
Billerica
1 job
Pittsfield
1 job
Somerville
1 job
Northampton
1 job

Chief Of Staff Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

TetraScience2 open roles
Boston Medical Center2 open roles
RTX1 open role

Top Industries Hiring

  • Technology & Software

What Massachusetts Employers Look For

The qualifications that appear most often in chief of staff jobs across Massachusetts.

  • Bachelor's degree in business, public policy, or a related field required
  • Five or more years of experience in operations, strategy, or executive support roles
  • Demonstrated ability to manage cross-functional projects and senior stakeholder relationships
  • Strong written and verbal communication skills for board-level and executive audiences
  • Experience in life sciences, technology, or financial services preferred for Massachusetts roles
  • Proficiency with project management tools and comfort working in fast-moving organizational environments

Chief Of Staff Jobs in Massachusetts: Frequently Asked Questions

How do you become a chief of staff in Massachusetts?

There is no state-issued license or certification required to work as a chief of staff in Massachusetts. Most employers look for a bachelor's degree in business, public policy, or a related field, with a graduate degree increasingly common at larger institutions. The typical path runs through roles in strategy, operations, or executive coordination, often within Massachusetts's dominant sectors of life sciences, technology, or financial services, before stepping into a chief of staff position.

Which companies hire chief of staffs in Massachusetts?

Employers hiring chief of staffs in Massachusetts right now include TetraScience, Boston Medical Center, and RTX, based on current listings on Migrate Mate as of November 2026. Massachusetts's concentration of venture-backed startups, major hospital systems, and global financial firms means openings appear across a wide range of organization sizes and industries throughout the year.

Which Massachusetts cities have the most chief of staff jobs?

Boston, Cambridge, and Billerica are the Massachusetts cities with the most chief of staff openings. Boston anchors the market because it is home to major hospital systems, asset management firms, and a dense cluster of technology companies, while Cambridge draws demand from life sciences and university-affiliated organizations, and Waltham and the Route 128 corridor add volume from established technology and professional services employers.

Are there remote chief of staff jobs in Massachusetts?

Yes, but they are less common than in fully desk-based roles, since most chiefs of staff are expected to be present for executive meetings, board interactions, and operational decisions. About 90% of chief of staff openings tied to Massachusetts are remote or hybrid as of November 2026, with hybrid arrangements more prevalent than fully remote. The strategic planning and project coordination parts of the role are most likely to be performed off-site.

How can I get hired as a chief of staff in Massachusetts with little or no experience?

The most realistic entry path is through a chief of staff associate or junior chief of staff program, which organizations including major Boston-area hospital networks and venture-backed technology companies use to develop early-career candidates. Roles such as executive coordinator, strategy analyst, or operations associate at Massachusetts employers in life sciences or financial services are the most common lateral moves into a first chief of staff position. A graduate degree in business or public policy from one of Massachusetts's universities strengthens a candidate's profile considerably.

Where can I find and apply to chief of staff jobs in Massachusetts?

You can find and apply to chief of staff jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings across industries and experience levels. Search the listings for roles that match your background and apply directly to the ones that fit.

See All 20 Chief Of Staff Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

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