Clinical Informatics Specialist Jobs in Massachusetts
Clinical Informatics Specialist jobs in Massachusetts are among the most active in the country, concentrated in academic medical centers, integrated health systems, and life sciences organizations, with openings at every level from early-career analysts through senior implementation leads. Boston, Worcester, and Burlington anchor the bulk of hiring, where employers like Mass General Brigham, UMass Memorial Health, and Lahey Health maintain large informatics teams. The most in-demand specialties are EHR optimization, clinical decision support, and interoperability and data governance. Find a role that fits below and apply directly.
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JOB SUMMARY:
The Clinical Systems Informatics Analyst serves as a key liaison between clinical operations and Information Technology, combining clinical workflow expertise with application analysis, design, build, implementation, and optimization.
This position works closely with clinicians, operational leaders, providers, and IT teams to translate clinical needs into effective technology solutions within the electronic health record (EHR) and other clinical applications. The analyst evaluates workflows, identifies opportunities for improvement, supports system configuration and implementation, and helps optimize clinical systems to improve patient care, safety, efficiency, and the user experience.
The ideal candidate has direct clinical experience, a strong understanding of healthcare workflows, strong analytical and technical aptitude, and an interest in using technology to improve clinical care. Previous EHR or clinical application experience is preferred but not required. A nursing background may be beneficial but is not required.
DUTIES AND RESPONSIBILITIES:
- Serves as a liaison between clinicians, providers, operational leaders, Information Technology, and vendors to identify needs and develop effective clinical technology solutions.
- Applies clinical workflow knowledge to the design, configuration, build, implementation, support, and optimization of the EHR and other clinical applications.
- Analyzes clinical and operational workflows and recommends opportunities for standardization, improved efficiency, patient safety, usability, and automation.
- Gathers and translates clinical and operational requirements into system configuration, application design, and workflow solutions.
- Performs or supports application configuration, build, testing, validation, implementation, upgrades, enhancements, and integrations for assigned clinical systems.
- Troubleshoots application and workflow issues, identifies root causes, coordinates resolution, and documents system changes and decisions.
- Partners with clinical leaders and frontline staff to evaluate system performance, identify optimization opportunities, and support adoption of new technology and workflows.
- Provides education, coaching, at-the-elbow support, and guidance to users and super users as needed.
- Participates in application governance, change control, project activities, system upgrades, and new clinical service or departmental implementations.
- Maintains knowledge of assigned applications, clinical informatics practices, regulatory requirements, patient safety principles, and emerging healthcare technology.
- Participates in an on-call support rotation and provides after-hours support for critical clinical applications and operational issues as required.
- Performs other duties and responsibilities as assigned.
EDUCATION AND RELATED EXPERIENCE:
Required:
- Bachelor’s degree in nursing, allied health, healthcare administration, health informatics, information systems, or a related field, or an equivalent combination of education and relevant experience.
- Minimum of three years (3) of healthcare experience with a strong understanding of clinical operations and workflows.
- Minimum of three years (3) of Direct clinical experience in an acute care, ambulatory, ancillary, or other patient-care environment.
- Demonstrated ability to analyze clinical workflows, identify problems, and develop practical solutions.
- Strong technical aptitude and demonstrated ability to learn new systems and technologies.
- Strong analytical, organizational, communication, and problem-solving skills.
- Ability to effectively collaborate with clinical, operational, and technical stakeholders.
Preferred:
- Experience working with an electronic health record or other clinical information system.
- Experience configuring, building, implementing, supporting, or optimizing an EHR or clinical application.
- Experience with MEDITECH Expanse or another enterprise EHR platform.
- Experience participating in clinical application implementations, upgrades, testing, workflow design, or optimization initiatives.
- Clinical licensure or certification in nursing, respiratory therapy, pharmacy, laboratory, radiology, rehabilitation, or another healthcare discipline.
- Informatics, healthcare technology, project management, or related professional certification.
Location: Merrimack Health · Information Systems
Schedule: 8:30am - 5:00pm, 40
See All 7 Clinical Informatics Specialist Jobs in Massachusetts
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Find JobsClinical Informatics Specialist Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Clinical Informatics Specialist Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring


Top Industries Hiring
- Technology & Software
- Biotechnology & Pharmaceuticals
What Massachusetts Employers Look For
The qualifications that appear most often in clinical informatics specialist jobs across Massachusetts.
- Bachelor's degree in health informatics, nursing, clinical sciences, or a related field
- Experience with Epic, Cerner, or another major EHR platform in a clinical setting
- Familiarity with HL7, FHIR, and health data interoperability standards
- Clinical background as a nurse, pharmacist, or allied health professional preferred
- AMIA or AHIMA informatics certification such as RHIA, CHDA, or NI-BC valued
- Ability to translate clinical workflows into system requirements and training materials
Clinical Informatics Specialist Jobs in Massachusetts: Frequently Asked Questions
How do you become a clinical informatics specialist in Massachusetts?
Most clinical informatics specialists in Massachusetts enter the field with a bachelor's degree in health informatics, nursing, or a clinical discipline, often paired with direct patient care or health IT experience. Massachusetts does not require a state-issued informatics license, but employers consistently value certifications such as the ANCC Nursing Informatics certification (NI-BC) or AHIMA credentials. Large academic medical centers in the Boston area frequently prefer candidates with both a clinical background and demonstrated EHR project experience.
Which companies hire clinical informatics specialists in Massachusetts?
Employers hiring clinical informatics specialists in Massachusetts right now include CVS Health, InterSystems, and Merrimack Health, based on current listings on Migrate Mate as of October 2026. Massachusetts's density of academic medical centers and integrated health systems means demand is spread across both large hospital networks and mid-size regional health organizations throughout the state.
Which Massachusetts cities have the most clinical informatics specialist jobs?
Boston, Massachusetts, and Salem account for the most clinical informatics specialist openings in Massachusetts. Boston drives the largest share because of its concentration of academic medical centers and large integrated systems, while Worcester reflects the growth of UMass Memorial Health and regional community health networks, and Burlington serves as a hub for Lahey Health and health IT vendors operating north of Boston.
Are there remote clinical informatics specialist jobs in Massachusetts?
Yes, and more than most healthcare roles, because the work centers on system configuration, data analysis, and training rather than direct patient care. About 50% of clinical informatics specialist openings tied to Massachusetts are remote or hybrid as of October 2026, reflecting the desk-based and analytical nature of the position. Roles focused on EHR reporting, interoperability project management, and clinical decision support are the most likely to offer remote flexibility.
How can I get hired as a clinical informatics specialist in Massachusetts with little or no experience?
The most realistic entry path is transitioning from a clinical role such as registered nurse, medical coder, or clinical analyst, where you already work inside EHR systems daily. Mass General Brigham and UMass Memorial Health both run structured onboarding programs that bring clinical staff into informatics support roles. Earning an Epic or Cerner end-user certification, or completing a graduate certificate in health informatics through a Massachusetts institution, gives candidates without project experience a concrete credential that opens doors to junior analyst and implementation support positions.
Where can I find and apply to clinical informatics specialist jobs in Massachusetts?
You can find and apply to clinical informatics specialist jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings. Find roles that fit your experience and apply directly to the employers posting them.
See All 7 Clinical Informatics Specialist Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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