Clinical Project Manager Jobs in South Dakota

Clinical Project Manager jobs in South Dakota are concentrated in Sioux Falls, Rapid City, and Aberdeen, where organizations like Sanford Health, Avera Health, and Monument Health anchor the state's clinical research and trial management activity. Demand is strongest in oncology, cardiovascular research, and multi-site trial coordination, with openings ranging from entry-level coordinators stepping into project oversight to senior managers leading regulatory submissions. South Dakota's mid-sized health systems run lean teams, so clinical project managers here tend to carry broader portfolios than counterparts at larger coastal institutions. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles72
Top employerMonument Health
Top citySioux Falls, SD
Cities hiring15
Work type88% On-site
Top industryHealthcare

Showing 5 of 72+ Clinical Project Manager jobs

CVS Health
Clinical Pharmacist, UM Development
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CVS Health
New 1m ago
Clinical Pharmacist, UM Development
CVS Health
South Dakota
Clinical Support
Healthcare Administration
Medical Specialists
Bachelor of Science
10,000+

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Thermo Fisher Scientific
Clinical Research Associate II - US Central - Multiple Therapeutic Areas Available
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Thermo Fisher Scientific
New 1m ago
Clinical Research Associate II - US Central - Multiple Therapeutic Areas Available
Thermo Fisher Scientific
South Dakota
Clinical Support
Healthcare Administration
Medical Specialists
On-Site
Bachelor's degree
10,000+

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US Department of Veterans Affairs
Lead Medical Support Assistant-Surgical Care
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US Department of Veterans Affairs
New 1m ago
Lead Medical Support Assistant-Surgical Care
US Department of Veterans Affairs
Fort Meade, South Dakota
Clinical Support
Healthcare Administration
Medical Specialists
On-Site
High school
10,000+

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Atrium Hospitality
PM Maintenance Technician
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Atrium Hospitality
New 1m ago
PM Maintenance Technician
Atrium Hospitality
Sioux Falls, South Dakota
Health & Safety
Maintenance & Repair
Skilled Trades
HVAC Certification
1,001-5,000

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LifeScape
Complex Pediatric Clinical Psychologist
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LifeScape
New 1m ago
Complex Pediatric Clinical Psychologist
LifeScape
Sioux Falls, South Dakota
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
Doctoral degree in clinical psychology
1,001-5,000

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Clinical Project Manager Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Sioux Falls
30 jobs
Rapid City
16 jobs
Pierre
7 jobs
Custer
3 jobs
Spearfish
3 jobs
Lead
1 job
Canton
1 job
Eureka
1 job
Winner
1 job

Clinical Project Manager Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

  • Monument Health
    Monument Health16
  • Sanford Health
    Sanford Health11
  • CVS Health
    CVS Health4
  • Sanford Bismarck
    Sanford Bismarck2
  • The Bancorp
    The Bancorp2

Top Industries Hiring

  • Healthcare & Medical Services28
  • Consulting & Professional Services3
  • Banking & Financial Services2
  • Science & Research1
  • Agriculture & Farming1

What South Dakota Employers Look For

The qualifications that appear most often in clinical project manager jobs across South Dakota.

  • Bachelor's degree in life sciences, nursing, or a related clinical field required
  • PMP or CAPM certification strongly preferred by South Dakota health system employers
  • Minimum two to five years of clinical trial or research coordination experience
  • Familiarity with ICH-GCP guidelines and FDA regulatory requirements for clinical studies
  • Proficiency with clinical trial management systems such as Medidata or Oracle
  • Strong cross-functional communication skills for coordinating investigators, sponsors, and sites

Clinical Project Manager Jobs in South Dakota: Frequently Asked Questions

How do you become a clinical project manager in South Dakota?

Most clinical project managers in South Dakota start with a bachelor's degree in a life science, nursing, or public health field and build experience as a clinical research coordinator or trial administrator. South Dakota does not require a state-issued license specific to this role, but earning a PMP credential through the Project Management Institute or a CCRC through the Association of Clinical Research Professionals strengthens applications at Sanford Health, Avera Health, and similar regional employers. Hands-on trial experience is the most consistent hiring requirement.

How much do clinical project managers make in South Dakota?

Clinical project managers in South Dakota earn a median of about $82,250 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $58,000 for the lowest 10% to over $130,400 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical project managers in South Dakota?

Employers hiring clinical project managers in South Dakota right now include Monument Health, Sanford Health, and CVS Health, based on current listings on Migrate Mate as of July 2026. Sanford Health and Avera Health are the state's largest and most consistent sources of clinical project management openings, with activity in Sioux Falls driving the majority of postings.

Which South Dakota cities have the most clinical project manager jobs?

Sioux Falls, Rapid City, and Pierre are the South Dakota cities with the most clinical project manager openings. Sioux Falls dominates because Sanford Health and Avera Health both operate major research and clinical operations hubs there, while Rapid City draws activity from Monument Health's growing trial program, and Aberdeen sees openings tied to regional Avera facilities and community health initiatives.

Are there remote clinical project manager jobs in South Dakota?

Yes, and more than many clinical roles, because clinical project management is largely desk-based work involving data oversight, vendor communication, and regulatory documentation rather than direct patient care. About 12% of clinical project manager openings tied to South Dakota are remote or hybrid as of July 2026, reflecting sponsors and contract research organizations listing positions without a required site presence. Startup-phase and sponsor-side roles tend to be the most fully remote.

How can I get hired as a clinical project manager in South Dakota with little or no experience?

The most realistic entry path is a clinical research coordinator role at Sanford Health or Avera Health, both of which hire coordinators without prior project management titles and promote internally into oversight positions. Lateral moves from regulatory affairs, data management, or quality assurance within a health system are common stepping stones. Completing a CCRC or earning a PMP while coordinating trials gives candidates a concrete credential edge, and Avera's research administration team in Sioux Falls is particularly known for developing coordinators into project managers over two to three years.

Where can I find and apply to clinical project manager jobs in South Dakota?

You can find and apply to clinical project manager jobs in South Dakota on Migrate Mate, which lists current openings from employers across the state. Search the roles available, find the ones that match your experience and location, and apply directly to the ones that fit.

See All 72 Clinical Project Manager Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

Find Clinical Project Manager Jobs