Clinical Project Manager Jobs in Pennsylvania
Clinical Project Manager jobs in Pennsylvania are in strong demand, with activity concentrated in pharmaceutical research, academic medical centers, contract research organizations, and health system operations across seniority levels from coordinator-track to senior program lead. The heaviest hiring is in Philadelphia, Pittsburgh, and the Greater Delaware Valley corridor, where anchors like Penn Medicine, UPMC, and Johnson & Johnson's domestic operations maintain consistent clinical operations teams. Oncology trial management, regulatory submissions oversight, and site management are the most in-demand specialties for the role in Pennsylvania right now. Find a role that fits below and apply directly.
Find Clinical Project Manager JobsOverview
Showing 5 of 9+ Clinical Project Manager jobs









Purpose:
UPMC Hillman Cancer Center is internationally recognized for its leadership in the prevention, detection, diagnosis, and treatment of cancer and is the region's only comprehensive cancer center designated by the National Cancer Institute. As the preeminent institution in western Pennsylvania for the delivery of cancer care, the performance of basic, translational, and clinical research, and the education of the next generation of cancer researchers and physicians, UPMC Hillman Cancer Center is exceptionally well-positioned to contribute to the global effort to reduce the burden of cancer.
UPMC Hillman Cancer Center is currently hiring a regular full-time Clinical Research Project Analyst to help support the Oncology Clinical Research Services team located at the Hillman Cancer Center in Shadyside/Pittsburgh, PA. This role will support the Financial Compliance Analysis and Budgets teams. It will be working Monday through Friday daylight hours with a remote schedule.
The Project Analyst will function as an integral member of the Hillman Cancer Center Clinical Trials Coverage Analysis and Budget team, supporting the operational and financial management of clinical research studies. This role is responsible for managing and triaging service center email accounts, ensuring timely and accurate responses to inquiries from internal and external stakeholders. The Project Analyst will develop, maintain, and enhance workflow dashboards and reporting tools to support team productivity, monitor key performance metrics, and identify opportunities for process improvement. Additional responsibilities include coordinating and managing relationships with external vendors, overseeing associated workflows to ensure compliance with established timelines and requirements, and serving as a resource for troubleshooting OnCore calendar and billing concerns. The individual will collaborate closely with clinical research, finance, and operational teams to support study start-up activities, facilitate efficient workflow processes, and contribute to the successful execution of clinical trial budgeting and coverage analysis activities.
The Clinical Research Services (CRS) team is made up of nearly 200 staff members who facilitate the development, implementation, coordination, internal data monitoring, and completion of oncology-focused trials at Hillman. These trials include institutional (investigator-initiated), multi-center cooperative group/National Clinical Trial Network (NCTN), consortium, and industry-sponsored trials. Using a disease-specific centers model for conducting clinical trials, CRS provides study development and implementation assistance, submissions to the FDA, IRB processing, patient recruitment, study coordination, study-specific training, data collection, and specimen collection and processing.
Responsibilities:
- Assist Management in defining and documenting tasks and duties within department.
- Identifies trends and process improvement opportunities across departments within operations.
- Process report requests as needed by Manager and Directors.
- Monitors operating performance against regional and national benchmarks.
- Perform complex project and data analysis as needed by Management.
- Develops cross-functional, change management and implementation strategies, ensuring that all of the participating parties have committed to effective implementation of the processes and procedures.
- Assist with achieving Operations division strategic goals as well as organizational goals
- Recommend and implement process improvement initiatives within the department as well as implementing process improvement initiatives based on management decision.
- Provide concise and timely status reporting as required
- Develop and maintain detailed project plans, this includes utilizing standard project documentation and methodology and project tracking and reporting procedures.
- Works with other managers to achieve efficiencies across integration of projects.
- Assists team members in resolving project problems, escalates issues when necessary, and facilities decision-making.
- Develops and implements key metrics to measure and report on progress of initiatives.
- Performs cost/benefit analysis
- Assures quality of information through business case and application level testing; validates test results to initial business needs.
Bachelor’s degree and 2 years’ experience or High School degree plus 5 years of experience.
Knowledge of clinical research protocol and budgeting preferred
Oncology experience preferred
Clinical Research/Trials experience strongly preferred
Prior work experience as a Project Coordinator highly preferred.
Excellent knowledge of spreadsheet and database software.
Must be very organized and deadline conscious.
Project Management knowledge and ability to manage multiple, complex, large-scale projects.
Minimum of four (4) years of experience in operations preferred.
Experience in health care insurance or health care industry preferred.
Excellent computer skills required, including Access, Excel, Microsoft Project, and other pertinent computer software packages.
Strong management, problem solving, organizational, and communication skills (oral and written).
This position requires effective planning and organizational skills.
This person must have the ability to perform planning for large initiatives/projects, managing all tasks required to providing services to meet client and business needs within budget and targeted deadlines.
Licensure, Certifications, and Clearances:
UPMC is an Equal Opportunity Employer/Disability/Veteran
See All 9 Clinical Project Manager Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Clinical Project Manager JobsClinical Project Manager Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Clinical Project Manager Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring


Top Industries Hiring
- Healthcare & Medical Services
What Pennsylvania Employers Look For
The qualifications that appear most often in clinical project manager jobs across Pennsylvania.
- Bachelor's degree in life sciences, nursing, or a related clinical field required
- Minimum two to five years of clinical trial or research operations experience
- PMP or CAPM certification preferred by most Pennsylvania research employers
- Demonstrated familiarity with FDA regulations, ICH-GCP guidelines, and IRB processes
- Proficiency with clinical trial management systems such as Medidata Rave or Veeva Vault
- Strong cross-functional communication skills for coordinating sites, sponsors, and CROs
Clinical Project Manager Jobs in Pennsylvania: Frequently Asked Questions
How do you become a clinical project manager in Pennsylvania?
The most direct path in Pennsylvania is a bachelor's degree in a life science, nursing, or health administration field followed by hands-on clinical trial experience as a clinical research coordinator or research associate. Pennsylvania does not require a state-issued license specifically for clinical project managers, but employers across Philadelphia and Pittsburgh strongly favor candidates who hold the Project Management Professional credential or the ACRP Certified Clinical Research Professional designation before advancing to a management title.
How much do clinical project managers make in Pennsylvania?
Clinical project managers in Pennsylvania earn a median of about $100,150 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $61,600 for the lowest 10% to over $160,560 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinical project managers in Pennsylvania?
Employers hiring clinical project managers in Pennsylvania right now include University of Pennsylvania, UPMC, and ICON, based on current listings on Migrate Mate as of September 2026. Pennsylvania's dense concentration of academic health systems, specialty CROs, and pharmaceutical manufacturers along the I-95 corridor makes it one of the more active states for this role year-round.
Which Pennsylvania cities have the most clinical project manager jobs?
The Pennsylvania cities with the most clinical project manager openings are Philadelphia, Pennsylvania, and Bethlehem. Philadelphia drives the largest share of postings because of its cluster of major health systems, pharmaceutical headquarters, and CRO regional offices, while Pittsburgh contributes consistently through UPMC's sprawling clinical research enterprise and Carnegie Mellon's affiliated health technology initiatives.
Are there remote clinical project manager jobs in Pennsylvania?
Yes, and more than most clinical roles, because clinical project management is largely coordination, documentation, and oversight work that does not require a physical bedside presence. About 67% of clinical project manager openings tied to Pennsylvania are remote or hybrid as of September 2026, reflecting how broadly sponsors and CROs have embraced distributed trial management teams. Study startup, vendor oversight, and reporting functions are the tasks most commonly performed fully remotely.
How can I get hired as a clinical project manager in Pennsylvania with little or no experience?
The most realistic entry path is starting as a clinical research coordinator or research associate at a Pennsylvania academic medical center or hospital, then building toward a project management title internally. UPMC, Penn Medicine, and Jefferson Health all run structured clinical research associate programs and regularly post coordinator-level openings that serve as a pipeline into project management. Earning the ACRP Clinical Research Associate credential while in a coordinator role signals readiness to move up and gives Pennsylvania candidates a concrete edge in a competitive applicant pool.
Where can I find and apply to clinical project manager jobs in Pennsylvania?
You can find and apply to clinical project manager jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings from employers actively hiring for the role. Search the listings, find roles that match your experience and location, and apply directly to the ones that fit.
See All 9 Clinical Project Manager Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Clinical Project Manager Jobs