Clinical Trial Manager Jobs in Boston, MA
Clinical Trial Manager jobs in Boston are concentrated in the Longwood Medical Area, Kendall Square, and the Seaport District, with demand driven by biopharma, academic medical centers, and CROs. Leading employers right now include Centessa Pharmaceuticals, Rapport Therapeutics, and IQVIA. See the openings below and apply to the ones that match your experience.
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Showing 5 of 32+ Clinical Trial Manager jobs
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
Does this position require Patient Care?
No
Essential Functions
- Identify and initiate communications with sites to obtain all relevant documents for project/trial.
- Collect and review the site’s essential regulatory documents for completeness prior to submitting to Regulatory for final review and/or approval.
- Advise research sites on protocol conduct, interpretation of protocol, and ensure resolution of issues.
- Update and maintain internal databases, tracking systems, project plans, and study files.
- Prepare presentation materials for internal and external meetings.
- Draft meeting agendas and minutes.
- Work with Project Manager to support trial processes and distribution of information and reports to monitors.
- Facilitate the implementation and ongoing process improvement of established policies and procedures for department/project/trial.
- Comply with applicable SOPs.
Qualifications
Bachelor's Degree Related Field of Study required
Can this role accept experience in lieu of a degree?
No
Licenses and Credentials
Experience
Research Related Experience 1-2 years required or Familiarity with EDC and CTMS systems 2-3 years preferred
Knowledge, Skills and Abilities
- Excellent Organizational Skills.
- Solid written and verbal communication skills.
- Strong sense of accountability, the ability to work autonomously.
- Ability to communicate effectively in a matrix environment.
- Ability to manage multiple tasks concurrently and to prioritize work appropriately.
Additional Job Details (if applicable)
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
Pay Range
Grade
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
Does this position require Patient Care?
No
Essential Functions
- Identify and initiate communications with sites to obtain all relevant documents for project/trial.
- Collect and review the site’s essential regulatory documents for completeness prior to submitting to Regulatory for final review and/or approval.
- Advise research sites on protocol conduct, interpretation of protocol, and ensure resolution of issues.
- Update and maintain internal databases, tracking systems, project plans, and study files.
- Prepare presentation materials for internal and external meetings.
- Draft meeting agendas and minutes.
- Work with Project Manager to support trial processes and distribution of information and reports to monitors.
- Facilitate the implementation and ongoing process improvement of established policies and procedures for department/project/trial.
- Comply with applicable SOPs.
Qualifications
Bachelor's Degree Related Field of Study required
Can this role accept experience in lieu of a degree?
No
Licenses and Credentials
Experience
Research Related Experience 1-2 years required or Familiarity with EDC and CTMS systems 2-3 years preferred
Knowledge, Skills and Abilities
- Excellent Organizational Skills.
- Solid written and verbal communication skills.
- Strong sense of accountability, the ability to work autonomously.
- Ability to communicate effectively in a matrix environment.
- Ability to manage multiple tasks concurrently and to prioritize work appropriately.
Additional Job Details (if applicable)
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
Pay Range
Grade
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
See All 32 Clinical Trial Manager Jobs in Boston
Find roles in Boston that match your experience and apply in just a few clicks.
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Who's Hiring
Clinical Trial Manager Jobs in Boston: Frequently Asked Questions
How do I get a clinical trial manager job in Boston?
Focus your search on the Longwood Medical Area, Kendall Square, and the Seaport District, where biopharma companies, CROs, and academic medical centers do most of their hiring. Candidates with therapeutic area depth, particularly in oncology, rare disease, or neurology, stand out in Boston's competitive market. Hands-on protocol management experience and familiarity with FDA regulatory requirements give you a clear edge over generalist applicants here.
Which companies hire clinical trial managers in Boston?
Boston clinical trial manager roles are posted by Centessa Pharmaceuticals, Rapport Therapeutics, and IQVIA and others right now, based on current listings on Migrate Mate as of October 2026. Boston's hiring mix is unusually diverse, ranging from global biopharma headquarters and mid-size biotech spinouts to contract research organizations and teaching hospitals affiliated with Harvard Medical School and Boston University.
Are there remote clinical trial manager jobs in Boston?
Yes, though remotely is limited given the role's on-site monitoring and site visit requirements. About 100% of clinical trial manager openings tied to Boston are remote or hybrid as of October 2026, mostly covering sponsor-side oversight and data management functions. Roles based at Kendall Square and Seaport biopharma firms are most likely to offer hybrid schedules for non-monitoring duties.
How can I get a clinical trial manager job in Boston with little or no experience?
The most realistic entry path in Boston is moving up from a clinical research coordinator role at one of the city's major academic medical centers, such as Mass General Brigham or Beth Israel Deaconess. Boston's concentration of phase I and II oncology trials creates genuine demand for coordinators ready to step into management. Pursuing an ACRP or SOCRA certification while coordinating active trials significantly strengthens a promotion case locally.
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See All 32 Clinical Trial Manager Jobs in Boston
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