BillionToOne H-1B Visa Sponsorship Jobs USA
BillionToOne sponsors H-1B visas for roles in its medical diagnostics and genomics work, particularly in engineering, bioinformatics, and scientific research. The company has an established sponsorship track record, making it a viable target for H-1B visa candidates with specialized backgrounds in medical device development and life sciences.
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Get Access To All JobsReady to redefine what's possible in molecular diagnostics?
Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
We are seeking a highly driven leader for one of the most critical and high-impact roles at BillionToOne: the Senior Director of Product Management, Oncology. In this role, you will essentially act as the General Manager for the entire oncology product line, owning the product roadmap for Northstar, our liquid biopsy product for therapy selection and monitoring. This is a unique opportunity for a GM-like product leader with strong end-to-end ownership, exceptional people management skills, and the ability to be both strategic and hands-on.
The ideal candidate is entrepreneurial, thrives in a fast-paced, dynamic environment, and can navigate the complexities of scaling innovative products in a competitive market. You will lead new assay development, drive product enhancements, and collaborate with diverse teams, including R&D, clinical, and engineering. You'll be responsible for ensuring our oncology products not only meet market demands but set the standard in the industry.
This role is a hybrid (onsite 3 days/week) position and reports directly to the Chief Product Officer.
Responsibilities:
- GM Ownership: Own the oncology product line from top to bottom, ensuring long-term strategic success while handling day-to-day tactical responsibilities.
- Market Expert & Product Visionary: Be the company's leading expert on user needs, market trends, and how BillionToOne's technology can solve critical problems in oncology diagnostics.
- Product Launch & Execution: Lead product launch strategies, overseeing every element from assay development to software apps, regulatory constraints, and customer experience.
- People Leadership: Manage and inspire a cross-functional team of R&D, clinical, engineering, and commercial experts, aligning their efforts towards the product's success.
- User Experience Champion: Design and deliver a seamless user experience across the entire testing process, in collaboration with UX designers and stakeholders.
- Drive Continuous Improvement: Monitor product performance, user feedback, and market shifts, making data-driven decisions to enhance product offerings and maintain leadership in the market.
Qualifications
- 5-10 years of product management experience with demonstrated end-to-end ownership of complex product lines
- Proven experience launching diagnostic testing products (oncology or NGS-based diagnostics preferred)
- GM-like mindset with strategic vision and hands-on execution skills
- Excellent people management and leadership capabilities across cross-functional teams
- Strong background in product launch strategy, go-to-market execution, and program management
- On-site position (relocation to SF Bay Area required)
Nice-To-Haves:
- Another advanced degree (Masters/PhD) in molecular biology, bioengineering, medicine, chemical biology, or a related field is strongly preferred
- Experience with launching and managing NGS-based diagnostic testing assays is a strong plus
Benefits And Perks:
- Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousands patients
- Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
- Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
- Supplemental fertility benefits coverage
- Retirement savings program including a 4% Company match
- Increase paid time off with increased tenure
- Latest and greatest hardware (laptop, lab equipment, facilities)
- Free daily on-site lunches provided from top eateries
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).
For this position, we offer a total compensation package of $474,416 per year, including a base pay range of $257,243 - $278,680 per year.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
For more information about how we protect your information, we encourage you to review our Privacy Policy.
BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA, a breakthrough that has already transformed the lives of over half a million patients worldwide.
Our Impact
Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth
From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding, including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition
Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Our Future
Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.
Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com
Ready to redefine what's possible in molecular diagnostics?
Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
We are seeking a highly driven leader for one of the most critical and high-impact roles at BillionToOne: the Senior Director of Product Management, Oncology. In this role, you will essentially act as the General Manager for the entire oncology product line, owning the product roadmap for Northstar, our liquid biopsy product for therapy selection and monitoring. This is a unique opportunity for a GM-like product leader with strong end-to-end ownership, exceptional people management skills, and the ability to be both strategic and hands-on.
The ideal candidate is entrepreneurial, thrives in a fast-paced, dynamic environment, and can navigate the complexities of scaling innovative products in a competitive market. You will lead new assay development, drive product enhancements, and collaborate with diverse teams, including R&D, clinical, and engineering. You'll be responsible for ensuring our oncology products not only meet market demands but set the standard in the industry.
This role is a hybrid (onsite 3 days/week) position and reports directly to the Chief Product Officer.
Responsibilities:
- GM Ownership: Own the oncology product line from top to bottom, ensuring long-term strategic success while handling day-to-day tactical responsibilities.
- Market Expert & Product Visionary: Be the company's leading expert on user needs, market trends, and how BillionToOne's technology can solve critical problems in oncology diagnostics.
- Product Launch & Execution: Lead product launch strategies, overseeing every element from assay development to software apps, regulatory constraints, and customer experience.
- People Leadership: Manage and inspire a cross-functional team of R&D, clinical, engineering, and commercial experts, aligning their efforts towards the product's success.
- User Experience Champion: Design and deliver a seamless user experience across the entire testing process, in collaboration with UX designers and stakeholders.
- Drive Continuous Improvement: Monitor product performance, user feedback, and market shifts, making data-driven decisions to enhance product offerings and maintain leadership in the market.
Qualifications
- 5-10 years of product management experience with demonstrated end-to-end ownership of complex product lines
- Proven experience launching diagnostic testing products (oncology or NGS-based diagnostics preferred)
- GM-like mindset with strategic vision and hands-on execution skills
- Excellent people management and leadership capabilities across cross-functional teams
- Strong background in product launch strategy, go-to-market execution, and program management
- On-site position (relocation to SF Bay Area required)
Nice-To-Haves:
- Another advanced degree (Masters/PhD) in molecular biology, bioengineering, medicine, chemical biology, or a related field is strongly preferred
- Experience with launching and managing NGS-based diagnostic testing assays is a strong plus
Benefits And Perks:
- Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousands patients
- Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
- Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
- Supplemental fertility benefits coverage
- Retirement savings program including a 4% Company match
- Increase paid time off with increased tenure
- Latest and greatest hardware (laptop, lab equipment, facilities)
- Free daily on-site lunches provided from top eateries
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).
For this position, we offer a total compensation package of $474,416 per year, including a base pay range of $257,243 - $278,680 per year.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
For more information about how we protect your information, we encourage you to review our Privacy Policy.
BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA, a breakthrough that has already transformed the lives of over half a million patients worldwide.
Our Impact
Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth
From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding, including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition
Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Our Future
Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.
Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com
Job Roles at BillionToOne
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Get Access To All JobsTips for Finding BillionToOne H-1B Jobs
Target roles that match H-1B specialty occupation criteria
BillionToOne's strongest H-1B candidates come from engineering, computational biology, and clinical science backgrounds. Focus your application on roles where your degree field directly aligns with the job requirements, this is what makes an H-1B petition approvable.
Confirm sponsorship willingness early in the process
Not every open role at BillionToOne will include H-1B sponsorship. Bring it up after an initial recruiter screen, once you've established interest on both sides. Asking before any conversation risks a premature rejection.
Understand where BillionToOne sits in the H-1B lottery cycle
For most candidates, H-1B sponsorship at BillionToOne means entering the annual April lottery. If you're on F-1 OPT, confirm your OPT expiration lines up with the October 1 start date, cap-gap rules may bridge any gap.
Use Migrate Mate to verify BillionToOne's sponsorship history
Migrate Mate surfaces verified H-1B sponsors so you can filter by real sponsorship history before applying. Checking BillionToOne's actual filing record gives you more confidence going into the interview process than relying on job posting language alone.
Prepare for a technically rigorous interview process
BillionToOne operates in a highly specialized area of medical diagnostics. Interviewers will probe depth of knowledge in your field. The stronger your technical case, the stronger the underlying H-1B petition your employer files with USCIS.
Ask about premium processing availability
If your start date is time-sensitive, ask BillionToOne's HR team whether they use USCIS premium processing for H-1B petitions. Premium processing reduces the adjudication window significantly and can matter if OPT is expiring close to your target start date.
BillionToOne H-1B Visa Sponsorship: Frequently Asked Questions
Does BillionToOne sponsor H-1B visas?
Yes, BillionToOne sponsors H-1B visas. The company has an active sponsorship history, particularly for technical and scientific roles in its medical diagnostics and genomics work. Sponsorship is not guaranteed for every open position, so confirming H-1B support directly with the recruiter early in the process is the right approach.
Which roles at BillionToOne are most likely to receive H-1B sponsorship?
H-1B sponsorship at BillionToOne is most common in roles that clearly meet USCIS specialty occupation standards. Engineering, bioinformatics, software development, clinical science, and research positions are the strongest candidates. Roles requiring a specific degree in a technical or scientific field are better positioned for approval than generalist positions.
How do I navigate the H-1B application process at BillionToOne?
Once BillionToOne extends an offer and confirms H-1B sponsorship, the company works with an immigration attorney to file a Labor Condition Application with the Department of Labor, followed by the H-1B petition with USCIS. Your role is to provide documentation of your degree, transcripts, and employment history. The process is employer-driven, but staying responsive to document requests keeps it on track.
How long does H-1B sponsorship take at BillionToOne?
For cap-subject H-1B petitions, the timeline is tied to the annual lottery, with employment starting no earlier than October 1. From lottery selection to approval typically runs several months under standard processing. If BillionToOne uses premium processing, USCIS adjudicates the petition significantly faster. Cap-exempt scenarios, such as transfers from another H-1B employer, move on a different and generally shorter timeline.
How do I find H-1B jobs at BillionToOne as an international candidate?
Migrate Mate lists verified H-1B sponsors and lets you filter by company and sponsorship history, which makes it straightforward to identify open roles at BillionToOne that are realistically accessible to international candidates. Beyond the job search, tailor your application to the specific technical requirements of each role and be prepared to discuss your visa status clearly during the recruiter screen.
What is the prevailing wage for H-1B jobs at BillionToOne?
H-1B employers must pay at least the prevailing wage, which is determined when they file the Labor Condition Application with the Department of Labor. The rate is based on the role, location, and experience level, and ensures international hires are paid comparably to U.S. workers in the same position. You can look up prevailing wage rates for any occupation and location using the DOL's OFLC Wage Search tool.