E-3 Visa Biomedical Engineer Jobs
Biomedical Engineer roles qualify as E-3 visa specialty occupations under the visa's degree requirement, making E-3 sponsorship accessible at medical device firms, hospital systems, and research institutions across the U.S. Unlike the H-1B visa, there's no lottery and no annual cap, so Australian engineers can apply as soon as they have a qualifying job offer.
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BSD MED - General Internal Medicine
About the Department
The Precision Health Informatics Lab (PHIL), led by Dr. Joshua Denny, MD, MS, develops and applies computational and informatics methods to translate large-scale genomic and clinical data into actionable insights about human health and disease. The lab's work sits at the intersection of genomics, electronic health record (EHR) data, and population-scale biobank research, with a focus on discovering gene-disease relationships, characterizing the clinical effects of genetic variation, and enabling precision medicine applications. A growing part of this work involves machine learning, large language models, and generative AI, which the lab uses to extract identify patterns across heterogeneous data sources and accelerate the pace of genomic discovery.
A central focus of the lab is phenomics, the integrative use of EHR-derived and survey-based phenotype data to power genetic and multiomic discovery. The lab develops and applies methods such as phenome-wide association studies (PheWAS), which test genetic variants against the full breadth of clinical phenotypes captured in health records, as well as traditional genome-wide association study (GWAS) approaches on complex phenotypes. PHIL builds and maintains computable phenotype algorithms, reproducible, data-driven definitions of disease states, drug effects, and other clinical conditions, that integrate EHR data, survey responses, and other health data sources.
We also seek to use large scale biobank data to uncover novel gene functions and previously unrecognized genetic diseases, an undertaking that depends on integrating genomic data with clinical, phenotypic, and knowledge-base resources at scale. PHIL collaborates broadly with clinical, genomic, and computational investigators to support biobank-scale studies, and is building a team of programmers, analysts, and scientists to sustain and expand this work.
Job Summary
The Senior Biomedical Informatics Programmer is integral to the ongoing operations of the Precision Health Informatics Lab (PHIL), providing critical scientific and bioinformatics programming support to enable large-scale biobank studies. This role will design, optimize, and maintain production-grade pipelines that connect genomic, phenotypic, and clinical data to support gene-disease discovery at scale, including studies using deep clinical characterization of individuals with rare genetic variants to uncover novel gene functions and genetic diseases.
Responsibilities
- Optimize and maintain best-practice pipelines for gene-disease association analyses, including genome-wide association studies (GWAS) and phenome-wide association studies (PheWAS).
- Build and refine computable phenotype algorithms for diseases, drug effects, and other clinical conditions by integrating EHR data with survey-based data sources.
- Develop scripts, pipelines, and software to analyze diverse health-related datasets, combining data across orthogonal sources — including EHR data, environmental exposures, and taxonomic/knowledge resources such as OMIM, the Human Phenotype Ontology, and DrugBank — to support genomic analyses.
- Provide broad-based programming and analytic support across a range of informatics and genomics research projects, including custom script development for analysis of public datasets and lab-generated data.
- Support the computational infrastructure underlying studies of rare genetic variants, helping enable discovery of novel gene functions and genetic diseases through clinical characterization.
- Collaborate with scientists, clinicians, and analysts to ensure pipelines are reliable, reproducible, and scalable for biobank-level data volumes.
- Generate public use resources.
- Leads implementation or modification of existing web-based bioinformatics tools.
- Provides expertise to biomedical informatics related concepts, applications, and tools.
- Performs other related work as needed.
Minimum Qualifications
Education:
Minimum requirements include a college or university degree in related field.
Work Experience:
Minimum requirements include knowledge and skills developed through 7+ years of work experience in a related job discipline.
Certifications:
Preferred Qualifications
Education:
- Advanced degree (MS or PhD preferred) in bioinformatics, computer science, computational biology, or related field.
Experience:
- Strong programming skills (e.g., Python, R, or similar) and experience building production data pipelines.
- Experience with genomic and/or EHR data formats and analysis (e.g., VCF, FHIR/OMOP, PheWAS/GWAS methods).
- Familiarity with biomedical ontologies and knowledge bases (OMIM, HPO, DrugBank).
- Experience working with large-scale biobank or clinical datasets.
Preferred Competencies
- Excellent verbal and written communication skills.
- Excellent interpersonal and customer service skills.
- Excellent organizational skills, ability to maintain files.
- Proficiency with word processing applications, preparing presentations, spreadsheets and databases.
- Ability to maintain calm and courteous demeanor and to work productively despite heavy workload, competing priorities, complex problems, and tight deadlines.
- Ability to exercise sound judgment and excellent problem-solving skills.
- Ability to exercise flexibility and contribute to the overall work of the team.
- Considerable skill in working both independently and as a team member.
- Ability to take initiative.
Application Documents
- Resume/CV (required)
- Cover Letter (required)
The University of Chicago uses AI-assisted tools to streamline and augment some recruitment processes; however, AI is not used to make hiring decisions.
When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.
Job Family
Research
Role Impact
Individual Contributor
Scheduled Weekly Hours
40
Drug Test Required
No
Health Screen Required
No
Motor Vehicle Record Inquiry Required
No
Pay Rate Type
Salary
FLSA Status
Exempt
Pay Range
$100,000.00 - $150,000.00
The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.
Benefits Eligible
Yes
The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.
Posting Statement
The University of Chicago is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.
Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.
All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.
The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: http://securityreport.uchicago.edu. Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.
Department
BSD MED - General Internal Medicine
About the Department
The Precision Health Informatics Lab (PHIL), led by Dr. Joshua Denny, MD, MS, develops and applies computational and informatics methods to translate large-scale genomic and clinical data into actionable insights about human health and disease. The lab's work sits at the intersection of genomics, electronic health record (EHR) data, and population-scale biobank research, with a focus on discovering gene-disease relationships, characterizing the clinical effects of genetic variation, and enabling precision medicine applications. A growing part of this work involves machine learning, large language models, and generative AI, which the lab uses to extract identify patterns across heterogeneous data sources and accelerate the pace of genomic discovery.
A central focus of the lab is phenomics, the integrative use of EHR-derived and survey-based phenotype data to power genetic and multiomic discovery. The lab develops and applies methods such as phenome-wide association studies (PheWAS), which test genetic variants against the full breadth of clinical phenotypes captured in health records, as well as traditional genome-wide association study (GWAS) approaches on complex phenotypes. PHIL builds and maintains computable phenotype algorithms, reproducible, data-driven definitions of disease states, drug effects, and other clinical conditions, that integrate EHR data, survey responses, and other health data sources.
We also seek to use large scale biobank data to uncover novel gene functions and previously unrecognized genetic diseases, an undertaking that depends on integrating genomic data with clinical, phenotypic, and knowledge-base resources at scale. PHIL collaborates broadly with clinical, genomic, and computational investigators to support biobank-scale studies, and is building a team of programmers, analysts, and scientists to sustain and expand this work.
Job Summary
The Senior Biomedical Informatics Programmer is integral to the ongoing operations of the Precision Health Informatics Lab (PHIL), providing critical scientific and bioinformatics programming support to enable large-scale biobank studies. This role will design, optimize, and maintain production-grade pipelines that connect genomic, phenotypic, and clinical data to support gene-disease discovery at scale, including studies using deep clinical characterization of individuals with rare genetic variants to uncover novel gene functions and genetic diseases.
Responsibilities
- Optimize and maintain best-practice pipelines for gene-disease association analyses, including genome-wide association studies (GWAS) and phenome-wide association studies (PheWAS).
- Build and refine computable phenotype algorithms for diseases, drug effects, and other clinical conditions by integrating EHR data with survey-based data sources.
- Develop scripts, pipelines, and software to analyze diverse health-related datasets, combining data across orthogonal sources — including EHR data, environmental exposures, and taxonomic/knowledge resources such as OMIM, the Human Phenotype Ontology, and DrugBank — to support genomic analyses.
- Provide broad-based programming and analytic support across a range of informatics and genomics research projects, including custom script development for analysis of public datasets and lab-generated data.
- Support the computational infrastructure underlying studies of rare genetic variants, helping enable discovery of novel gene functions and genetic diseases through clinical characterization.
- Collaborate with scientists, clinicians, and analysts to ensure pipelines are reliable, reproducible, and scalable for biobank-level data volumes.
- Generate public use resources.
- Leads implementation or modification of existing web-based bioinformatics tools.
- Provides expertise to biomedical informatics related concepts, applications, and tools.
- Performs other related work as needed.
Minimum Qualifications
Education:
Minimum requirements include a college or university degree in related field.
Work Experience:
Minimum requirements include knowledge and skills developed through 7+ years of work experience in a related job discipline.
Certifications:
Preferred Qualifications
Education:
- Advanced degree (MS or PhD preferred) in bioinformatics, computer science, computational biology, or related field.
Experience:
- Strong programming skills (e.g., Python, R, or similar) and experience building production data pipelines.
- Experience with genomic and/or EHR data formats and analysis (e.g., VCF, FHIR/OMOP, PheWAS/GWAS methods).
- Familiarity with biomedical ontologies and knowledge bases (OMIM, HPO, DrugBank).
- Experience working with large-scale biobank or clinical datasets.
Preferred Competencies
- Excellent verbal and written communication skills.
- Excellent interpersonal and customer service skills.
- Excellent organizational skills, ability to maintain files.
- Proficiency with word processing applications, preparing presentations, spreadsheets and databases.
- Ability to maintain calm and courteous demeanor and to work productively despite heavy workload, competing priorities, complex problems, and tight deadlines.
- Ability to exercise sound judgment and excellent problem-solving skills.
- Ability to exercise flexibility and contribute to the overall work of the team.
- Considerable skill in working both independently and as a team member.
- Ability to take initiative.
Application Documents
- Resume/CV (required)
- Cover Letter (required)
The University of Chicago uses AI-assisted tools to streamline and augment some recruitment processes; however, AI is not used to make hiring decisions.
When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.
Job Family
Research
Role Impact
Individual Contributor
Scheduled Weekly Hours
40
Drug Test Required
No
Health Screen Required
No
Motor Vehicle Record Inquiry Required
No
Pay Rate Type
Salary
FLSA Status
Exempt
Pay Range
$100,000.00 - $150,000.00
The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.
Benefits Eligible
Yes
The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.
Posting Statement
The University of Chicago is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.
Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.
All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.
The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: http://securityreport.uchicago.edu. Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.
See all 38+ E-3 Visa Biomedical Engineer Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new E-3 Visa Biomedical Engineer Jobs.
Get Access To All JobsTips for Finding E-3 Visa Sponsorship as a Biomedical Engineer
Verify your degree meets specialty occupation standards
Australian three-year biomedical engineering degrees are generally accepted as equivalent to a U.S. four-year bachelor's for E-3 purposes, but have your credentials evaluated before applying so your employer can confirm the match in their LCA filing.
Target employers with active DOL LCA histories
Search the DOL's Foreign Labor Certification disclosure data to identify hospitals, medical device manufacturers, and university research labs that have certified LCAs for biomedical engineers before. These employers already understand the sponsorship process and won't need educating.
Clarify your employment structure before the offer stage
Contract staffing arrangements and third-party client sites complicate E-3 LCA filings for biomedical engineers. Confirm with your prospective employer whether you'll be a direct hire, since staffing agency placements require the agency, not the end client, to be the E-3 petitioner.
Use Migrate Mate's E-3 filing service for the LCA and consulate prep
Once you have a job offer, use Migrate Mate's E-3 filing service to handle your LCA submission to DOL and prepare your consulate packet. The service manages prevailing wage documentation and DS-160 preparation, reducing the back-and-forth between you and your employer.
Frame your role around specialty occupation criteria in job offers
Ask your employer to confirm the offer letter specifies a bachelor's degree in biomedical engineering or a related engineering discipline as a minimum requirement. A letter that says 'degree preferred' rather than 'required' can create problems at the consulate interview.
Account for USCIS LCA certification timing in your start date negotiation
DOL typically certifies LCAs within seven business days, but your employer needs to post the LCA notice at the worksite for ten business days before filing. Build at least three weeks of lead time into your negotiated start date to avoid certification delays affecting your consulate appointment.
E-3 Visa Biomedical Engineer: Frequently Asked Questions
How do I find Biomedical Engineer jobs with E-3 sponsorship?
Migrate Mate lets you search specifically for Biomedical Engineer roles where employers are open to E-3 sponsorship, filtering out positions that won't support Australian visa applicants. Because the E-3 has no lottery and no annual cap, employers don't face the same uncertainty they do with H-1B, which often makes them more willing to sponsor qualified candidates.
How much does it cost to get an E-3 visa?
Migrate Mate's E-3 filing service covers the entire process for $499, including the Labor Condition Application, visa document preparation, and consulate appointment guidance. Traditional immigration lawyers charge $2,000–$5,000+ for the same work. The E-3 has less paperwork than most work visas, so paying thousands for legal help is usually unnecessary.
Does Biomedical Engineering qualify as a specialty occupation for the E-3 visa?
Yes. Biomedical engineering meets the E-3 specialty occupation definition because the role theoretically and practically requires at least a bachelor's degree in biomedical engineering, mechanical engineering, or a closely related discipline. Roles involving device design, clinical systems, or regulatory compliance at hospitals and medical device companies consistently satisfy this standard. Your employer documents this requirement in the LCA they file with DOL.
How does the E-3 compare to the H-1B for Biomedical Engineers?
The E-3 is significantly more accessible for Australian biomedical engineers because it carries a 10,500 annual allocation that has never been fully used, and there's no lottery. The H-1B runs an oversubscribed lottery each April, meaning qualified engineers are often denied the chance to apply at all. Both visas require a specialty occupation showing and an employer-sponsored LCA, but the E-3 allows you to apply as soon as you have an offer.
Can I switch Biomedical Engineer employers while on an E-3?
Yes, but each employer change requires a new LCA and a new E-3 visa stamp from an Australian consulate. Unlike the H-1B, the E-3 doesn't support portability after an I-129 transfer, so you'll need to complete the full filing process with your new employer before starting work. Plan for at least two to four weeks of LCA certification and consulate scheduling lead time.