H-1B Visa Senior Statistical Programmer Jobs
Senior Statistical Programmer roles sit squarely within H-1B visa specialty occupation territory, requiring a bachelor's degree or higher in statistics, biostatistics, or a related quantitative field. Pharma, biotech, and CRO employers file LCAs through DOL before sponsoring, and most treat H-1B fees as a standard cost of hiring specialized clinical trial talent.
Find H-1B Visa Senior Statistical Programmer JobsOverview
Showing 5 of 35+ Senior Statistical Programmer jobs
Have you applied for this role?
Have you applied for this role?
Have you applied for this role?
Have you applied for this role?
Have you applied for this role?
See all 35+ Senior Statistical Programmer Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Senior Statistical Programmer roles.
Get Access To All JobsJob Description:
We are seeking a highly motivated and qualified individual to join our Clinical Department as a Senior Statistical Programmer and work as part of a team to drive success. Ideal candidates will be self-motivated, independent, committed to the generation of high-quality data within a fast-paced and innovative research team. The Senior Statistical Programmer will serve as the lead statistical programmer and is responsible for statistical programming activities such as designing, developing, validating, updating, and documenting SAS programs to generate analysis datasets, data listings, summary tables, and statistical graphs supporting statistical analyses. This position requires close collaboration with cross-functional teams to ensure the integrity and accuracy of clinical data used in regulatory filings and internal reporting.
Responsibilities:
- Independently develop, validate, document and troubleshoot SAS programs for the preparation of periodic internal reports, regulatory submissions, and ad hoc analyses.
- Create and maintain analysis and submission datasets (ADaM, SDTM) in compliance with CDISC standards and regulatory guidance.
- Design, develop, validate, update, and document SAS programs to generate analysis datasets, data listings, tables, and graphs of high quality in a timely manner.
- Support submission activities including preparation of data packages, eCTD deliverables, and responses to regulatory agencies.
- Communicate with team members about statistical programming related to trial timelines, data quality, and results interpretation.
- Develop software tools, SAS macros and utilities to automate programming activities and improve programming efficiency and quality.
- Create SAS macros or other tools to enhance the efficient delivery of statistical services, providing associated documentation and staff training as needed.
- Program quality checks for clinical study raw data and report findings.
- Review or author SDTM and ADaM specifications and datasets.
- Manage CROs, including reviewing or validating statistical deliverables of vendors.
- Provides input in the design and development of case report forms.
- Contribute to the preparation of research reports and presentations for internal project teams, leadership team, and external audience.
- Establish and maintain excellent working relationships with critical collaborative partners throughout the company.
Requirements
- Bachelor's degree in Biostatistics, Mathematics, Statistics, Computer Science, or related field
- Minimum 6 years' experience in bio-pharma statistical programming
- Advanced SAS programming skills in SAS/Base, SAS/Macro, SAS/STAT, SAS/Graph, and SAS/SQL with a demonstrated mastery of SAS/STAT procedures
- Strong expertise in CDISC including SDTM, ADaM, and CDASH
- Extensive experience in SAS macro functions and dynamic code generations
- Experience in regulatory submissions (e.g., NDAs and DSURs)
- High attention to detail, with a focus on quality and traceability in all deliverables
- Strong interpersonal and teamwork skills with a collaborative mindset and the ability to manage multiple priorities in a fast-paced and dynamic environment with shifting timelines and evolving needs
- Take initiatives to solve problems proactively and think critically
- Willing to adapt to changing business needs, able to pivot between tasks
- Able to make complex programming and data-related decisions independently
- Comprehensive knowledge and deep understanding of statistical programming environments, processes, procedures, and roles for clinical development from Phase 1 through regulatory submission
- Up to date with CDISC standards, industry trends, best practices, and statistical programming methodology.
Job Description:
We are seeking a highly motivated and qualified individual to join our Clinical Department as a Senior Statistical Programmer and work as part of a team to drive success. Ideal candidates will be self-motivated, independent, committed to the generation of high-quality data within a fast-paced and innovative research team. The Senior Statistical Programmer will serve as the lead statistical programmer and is responsible for statistical programming activities such as designing, developing, validating, updating, and documenting SAS programs to generate analysis datasets, data listings, summary tables, and statistical graphs supporting statistical analyses. This position requires close collaboration with cross-functional teams to ensure the integrity and accuracy of clinical data used in regulatory filings and internal reporting.
Responsibilities:
- Independently develop, validate, document and troubleshoot SAS programs for the preparation of periodic internal reports, regulatory submissions, and ad hoc analyses.
- Create and maintain analysis and submission datasets (ADaM, SDTM) in compliance with CDISC standards and regulatory guidance.
- Design, develop, validate, update, and document SAS programs to generate analysis datasets, data listings, tables, and graphs of high quality in a timely manner.
- Support submission activities including preparation of data packages, eCTD deliverables, and responses to regulatory agencies.
- Communicate with team members about statistical programming related to trial timelines, data quality, and results interpretation.
- Develop software tools, SAS macros and utilities to automate programming activities and improve programming efficiency and quality.
- Create SAS macros or other tools to enhance the efficient delivery of statistical services, providing associated documentation and staff training as needed.
- Program quality checks for clinical study raw data and report findings.
- Review or author SDTM and ADaM specifications and datasets.
- Manage CROs, including reviewing or validating statistical deliverables of vendors.
- Provides input in the design and development of case report forms.
- Contribute to the preparation of research reports and presentations for internal project teams, leadership team, and external audience.
- Establish and maintain excellent working relationships with critical collaborative partners throughout the company.
Requirements
- Bachelor's degree in Biostatistics, Mathematics, Statistics, Computer Science, or related field
- Minimum 6 years' experience in bio-pharma statistical programming
- Advanced SAS programming skills in SAS/Base, SAS/Macro, SAS/STAT, SAS/Graph, and SAS/SQL with a demonstrated mastery of SAS/STAT procedures
- Strong expertise in CDISC including SDTM, ADaM, and CDASH
- Extensive experience in SAS macro functions and dynamic code generations
- Experience in regulatory submissions (e.g., NDAs and DSURs)
- High attention to detail, with a focus on quality and traceability in all deliverables
- Strong interpersonal and teamwork skills with a collaborative mindset and the ability to manage multiple priorities in a fast-paced and dynamic environment with shifting timelines and evolving needs
- Take initiatives to solve problems proactively and think critically
- Willing to adapt to changing business needs, able to pivot between tasks
- Able to make complex programming and data-related decisions independently
- Comprehensive knowledge and deep understanding of statistical programming environments, processes, procedures, and roles for clinical development from Phase 1 through regulatory submission
- Up to date with CDISC standards, industry trends, best practices, and statistical programming methodology.
See all 35+ H-1B Visa Senior Statistical Programmer Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new H-1B Visa Senior Statistical Programmer Jobs.
Get Access To All JobsTips for Finding H-1B Visa Sponsorship in Senior Statistical Programmer
Align your degree to SOC codes
USCIS evaluates specialty occupation fit by matching your degree field to the role's SOC code. For Senior Statistical Programmers, confirm your transcript reflects statistics, biostatistics, mathematics, or computer science before any employer files your petition.
Target employers with active LCA filings
Use Migrate Mate to filter Senior Statistical Programmer roles by verified DOL LCA history. Employers with recent filings in this occupation have already cleared the prevailing wage certification step, signaling a practiced H-1B sponsorship process.
Request SAS and CDISC credentials before applying
Pharma and CRO sponsors frequently specify CDISC SDTM and ADaM standards alongside SAS certification in LCA job descriptions. Holding documented credentials strengthens the specialty occupation argument USCIS reviews when adjudicating your I-129.
Verify the prevailing wage before negotiating
Run your target job title and work location through the OFLC Wage Search before entering salary discussions. Your employer must pay at least the DOL prevailing wage, and knowing the Level II or III threshold prevents offers that would fail LCA certification.
Confirm cap-exempt status for academic medical centers
Universities, nonprofit research organizations, and affiliated teaching hospitals are cap-exempt employers. If you're pursuing a Senior Statistical Programmer role at an academic medical center, H-1B sponsorship isn't subject to the annual 85,000-slot lottery and can start any time of year.
Use the 60-day grace period strategically
If your current H-1B ends due to a layoff, USCIS allows a 60-day grace period to secure a new sponsoring employer. Prioritize pharma and biotech companies actively filing LCAs so your next employer can submit an I-129 transfer petition before the window closes.
H-1B Visa Senior Statistical Programmer: Frequently Asked Questions
Does a Senior Statistical Programmer role qualify as a specialty occupation for H-1B purposes?
Yes. USCIS classifies Senior Statistical Programmer positions as specialty occupations because the role normally requires at least a bachelor's degree in statistics, biostatistics, mathematics, or a closely related field. The O*NET profile for this occupation confirms the degree requirement, which is a primary factor in USCIS's specialty occupation determination during I-129 adjudication.
Which industries sponsor H-1B visas most often for this role?
Pharmaceutical companies, contract research organizations, and biotech firms account for the large majority of H-1B LCA filings for Senior Statistical Programmer positions. Academic medical centers and government-affiliated research institutions also sponsor but are often cap-exempt, meaning they can file year-round without lottery selection. You can browse employers with verified filing histories on Migrate Mate.
How does the H-1B prevailing wage requirement affect Senior Statistical Programmer offers?
Before filing your LCA, your employer must certify to DOL that your offered wage meets or exceeds the prevailing wage for your job title and work location. For Senior Statistical Programmer roles, the wage level depends on experience and geographic market. You can verify applicable wage levels using the OFLC Wage Search before accepting or negotiating any offer.
Can a Senior Statistical Programmer transfer their H-1B to a new employer mid-project?
Yes. H-1B portability under AC21 lets you start working for a new sponsoring employer as soon as they file an I-129 transfer petition, without waiting for approval, provided your current H-1B is valid and you've maintained status. Clinical trial timelines don't pause H-1B transfers, so coordinating the petition timing around project milestones is straightforward.
What documents should a Senior Statistical Programmer prepare before an employer files the H-1B petition?
You'll need official transcripts showing a qualifying degree, a current resume mapping your programming experience to the specific role, and documentation of any relevant certifications such as SAS or CDISC credentials. If your degree is from outside the U.S., a credential evaluation from a NACES-member organization strengthens the specialty occupation argument USCIS reviews when adjudicating the I-129.