Nurse Practitioner Jobs in Iowa
Nurse Practitioner jobs in Iowa are concentrated in Des Moines, Cedar Rapids, and Iowa City, where systems like UnityPoint Health, MercyOne, and the University of Iowa Health Care are among the most consistent hirers. Family practice, urgent care, and psychiatric mental health are the specialties drawing the most demand statewide, with openings at every level from new graduates to experienced independent practitioners. Iowa's NP market is active across both urban health systems and rural critical access hospitals, which face ongoing staffing needs in underserved areas. Find a role that fits below and apply directly.
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Be Part of Something Radically Different
At Holon Health, we’re not just tweaking the system—we’re rebuilding it for the people it’s failed. We provide whole-person care to justice-involved individuals living with Substance Use Disorder (SUD)—care that meets people where they are, sees their full humanity, and builds pathways to long-term recovery, not short-term fixes.
Everything we do is designed to deviate from the status quo—from the way we treat our clients to the way we care for our team. We know that meaningful work can’t happen without flexibility, trust, and self-care, so we lead with a culture of compassion, inclusion, and respect. If you’re ready to join a team that’s rewriting the rules and centering people at every turn, read on.
Position Summary
Holon Health is seeking an experienced and compassionate Nurse Practitioner licensed in Iowa to support individuals with SUD through collaborative, integrated care. In this role, you’ll work closely with Care Navigators, Recovery Coaches, Case Managers, judicial partners, and community-based organizations to deliver care that addresses the full scope of a client’s mental, emotional, and physical needs.
This position offers remote flexibility and can be structured as either full-time (40 hours/week) or part-time (20 hours/week) depending on your availability and interest. You’ll provide telehealth-based assessments, medication management, and care coordination to support clients on their recovery journey—and be part of a forward-thinking team breaking down barriers to behavioral healthcare.
Essential Duties and Responsibilities
- Conduct health evaluations to assess substance use, co-occurring conditions, and overall functioning
- Diagnose health conditions and create individualized treatment plans
- Prescribe and manage medications, monitor for side effects, and adjust treatment as needed
- Collaborate with the Holon care team and external providers to deliver coordinated, whole-person care
- Serve as a clinical consultant on complex or high-need cases
- Educate clients and families on treatment plans, medications, and recovery support strategies
- Maintain accurate and timely documentation in compliance with ethical, legal, and medical standards
- Participate in team meetings, professional development, and continuous training
Who You Are
- A licensed and experienced Nurse Practitioner
- Deeply compassionate toward individuals living with SUD and mental health challenges
- Experienced in addiction medicine or psychiatry, with a commitment to person-centered care
- A strong collaborator who thrives in integrated and team-based care models
- Organized, flexible, and capable of navigating complex systems
- Clear and confident in virtual communication with both clients and team members
Education & Experience
- Active and unrestricted NP license in Iowa (multiple and additional state licenses are a plus)
- Active DEA license (and CDS where applicable)
- Several years of experience in behavioral health, addiction medicine, or psychiatry
- Board certification in specialty preferred
- Strong documentation skills and proficiency in EHR platforms
The Holon Way
We’re building a workplace that works for real life—because we know that when our people are well, they can do their best work. We offer:
- Competitive hourly compensation plus quarterly incentive
- Unlimited PTO
- Health, dental, vision, life and disability insurance for full-time team members
- 401(k) with company match for all
- A flexible schedule and room to grow
Our Commitment to DE&I
Diversity, equity, and inclusion aren’t just values at Holon—they’re the foundation of everything we do. We welcome people of all backgrounds, identities, and lived experiences, and we believe our team is stronger when it reflects the communities we serve. We’re proud to be an equal opportunity employer and we encourage candidates from underrepresented backgrounds to apply—even if you don’t meet every qualification.
See All 35 Nurse Practitioner Jobs in Iowa
Find roles in Iowa that match your experience and apply in just a few clicks.
Find Nurse Practitioner JobsNurse Practitioner Jobs by City in Iowa
Where Iowa roles are concentrated, by current openings.
Nurse Practitioner Job Market in Iowa
A snapshot from current Iowa openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Education
What Iowa Employers Look For
The qualifications that appear most often in nurse practitioner jobs across Iowa.
- Active Iowa nurse practitioner license issued by the Iowa Board of Nursing
- Master's or doctoral degree in nursing from an accredited NP program
- Current national board certification such as AANP or ANCC credentials
- Valid DEA registration for prescribing controlled substances in Iowa
- Two or more years of clinical NP or advanced practice nursing experience
- Current BLS and ACLS certifications required at time of hire
Nurse Practitioner Jobs in Iowa: Frequently Asked Questions
How do you become a nurse practitioner in Iowa?
You become a nurse practitioner in Iowa by completing an accredited master's or doctoral NP program, passing a national board certification exam through AANP or ANCC, and applying for an advanced registered nurse practitioner license through the Iowa Board of Nursing. Iowa requires you to submit proof of education, certification, and a supervising collaborating physician agreement if you practice in certain settings. The Iowa Board of Nursing processes applications and issues the ARNP designation.
How much do nurse practitioners make in Iowa?
Nurse practitioners in Iowa earn a median of about $130,160 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $107,990 for the lowest 10% to over $167,590 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire nurse practitioners in Iowa?
Iowa nurse practitioner roles are posted by US Department of Veterans Affairs, The University of Iowa, and Marathon Health and others right now, based on current listings on Migrate Mate as of August 2026. Large integrated health systems and federally qualified health centers across rural Iowa are particularly active, given the state's ongoing need for advanced practice providers in underserved communities.
Which Iowa cities have the most nurse practitioner jobs?
Des Moines, Council Bluffs, and Davenport are the Iowa cities with the most nurse practitioner openings. Des Moines leads because it anchors the state's largest health systems and corporate headquarters, while Iowa City's concentration around the University of Iowa Health Care and its academic medical center drives consistent demand, and Cedar Rapids supports a strong regional hospital market serving eastern Iowa.
Are there remote nurse practitioner jobs in Iowa?
Yes, but they're rare. About 18% of nurse practitioner openings tied to Iowa are remote or hybrid as of August 2026, reflecting that most NP work requires in-person patient care. The roles most likely to be remote are telehealth psychiatric mental health positions, where Iowa has seen growing demand tied to rural behavioral health access programs.
How can I get hired as a nurse practitioner in Iowa with little or no experience?
The most realistic entry path is applying to new-graduate NP residency or fellowship programs at large Iowa systems such as UnityPoint Health and University of Iowa Health Care, both of which have structured programs designed for new advanced practice providers. Candidates coming from RN or registered nurse roles in emergency, ICU, or primary care have the strongest footing for lateral movement. Completing your Iowa ARNP licensure and national board certification before applying, along with any rural health experience, gives you a measurable edge with critical access hospitals across the state.
Where can I find and apply to nurse practitioner jobs in Iowa?
You can find and apply to nurse practitioner jobs in Iowa on Migrate Mate, which lists current Iowa openings across health systems, clinics, and critical access hospitals. Find the roles that fit your specialty and experience level below and apply directly.
See All 35 Nurse Practitioner Jobs in Iowa
Find roles in Iowa that match your experience and apply in just a few clicks.
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