Operations Director Jobs in Waltham, MA

Operations Director jobs in Waltham are in strong demand, concentrated in the Waltham Watch Factory district, Prospect Hill, and the Route 128 corridor, across life sciences, technology services, and professional services. Employers hiring right now include Ardelyx, Cogent Biosciences, and Alkermes. Find a role that fits below and apply directly.

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Overview

Open roles196+
Top employerArdelyx
Work type66% Hybrid
Top credentialBachelor's degree in engineering
Companies hiring7

Showing 5 of 196+ Operations Director jobs

Wolters Kluwer
Director, GTM Operations
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Wolters Kluwer
Added 3d ago
Director, GTM Operations
Wolters Kluwer
Waltham, Massachusetts
Business Strategy
Corporate Development & M&A
Growth Marketing
$165k - $296k/yr
10,000+

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Alkermes, Inc.
Director, Clinical Operations
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Alkermes, Inc.
Added 1w ago
Director, Clinical Operations
Alkermes, Inc.
Waltham, Massachusetts
Business Development
Events & Tourism
Executive Leadership & C-Suite
Project Management
Hybrid
Bachelor's degree
1,001-5,000

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Ardelyx
Associate Director, QMS Operations
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Ardelyx
Added 1w ago
Associate Director, QMS Operations
Ardelyx
Waltham, Massachusetts
Business Operations
Program Management
Project Management
$176k - $215k/yr
Hybrid
Bachelor's degree in engineering
201-500

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Ardelyx
Executive Director, External Operations Quality
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Ardelyx
Added 1w ago
Executive Director, External Operations Quality
Ardelyx
Waltham, Massachusetts
Business Operations
Program Management
Project Management
$267k - $327k/yr
Hybrid
Bachelor's degree in engineering
201-500

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Thermo Fisher Scientific
Director, Customer Operations & Support
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Thermo Fisher Scientific
Added 2w ago
Director, Customer Operations & Support
Thermo Fisher Scientific
Waltham, Massachusetts
Business Development
Corporate Development & M&A
Executive Leadership & C-Suite
$140k - $180k/yr
Six Sigma Certification
10,000+

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See All 196+ Operations Director Jobs in Waltham

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Operations Director Job Market in Waltham

Who's Hiring

  • Ardelyx
    Ardelyx44
  • Cogent Biosciences
    Cogent Biosciences44
  • Alkermes
    Alkermes22
  • Wolters Kluwer
    Wolters Kluwer22
  • Dyne Therapeutics
    Dyne Therapeutics22

Top Industries Hiring

  • Biotechnology & Pharmaceuticals

Operations Director Jobs in Waltham: Frequently Asked Questions

How do I get a operations director job in Waltham?

The strongest path into an operations director role in Waltham is through the city's dense life sciences and technology services clusters along the Route 128 corridor. Employers in biotech, contract research, and SaaS tend to hire operations leaders who have managed multi-site teams or scaled processes in regulated environments. Candidates who can demonstrate experience with vendor management, compliance workflows, or operational systems integrations stand out in this market.

Which companies hire operations directors in Waltham?

Employers hiring operations directors in Waltham right now include Ardelyx, Cogent Biosciences, and Alkermes, based on current listings on Migrate Mate as of September 2026. Waltham's employer base skews toward mid-size to large firms in life sciences, technology, and professional services, many of which maintain regional headquarters or U.S. operations centers in the city.

Are there remote operations director jobs in Waltham?

Yes, though operations director roles are less remote-friendly than purely analytical positions since many involve managing facilities, vendor relationships, or on-site teams. About 66% of operations director openings tied to Waltham are remote or hybrid as of September 2026, with the hybrid share concentrated at technology and professional services firms rather than life sciences companies requiring regular on-site presence.

How can I get a operations director job in Waltham with little or no experience?

The most realistic entry path in Waltham is moving up through an operations manager or senior operations analyst role at one of the city's mid-size biotech or SaaS companies, many of which promote from within. Contract research organizations and technology services firms in the Route 128 corridor regularly hire operations coordinators and project leads as stepping stones. Building familiarity with quality management systems or ERP platforms common in these industries strengthens a candidate's case significantly.

Which industries hire the most operations directors in Waltham?

Most operations director openings in Waltham sit in Biotechnology & Pharmaceuticals, per current listings on Migrate Mate as of September 2026. Waltham's concentration of biotech firms, technology services companies, and professional services organizations along the Route 128 corridor drives consistent demand for operations leadership at the director level.

See All 196+ Operations Director Jobs in Waltham

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