Practice Assistant Jobs in North Carolina
Practice assistant jobs in North Carolina are concentrated in healthcare and legal settings, with steady demand from entry-level through senior administrative roles across a competitive mid-Atlantic job market. Charlotte, Raleigh, and Durham are the highest-volume hiring areas, where employers such as Atrium Health, Duke Health, and UNC Health maintain consistent openings. The most in-demand specialties are medical practice support, legal practice assistance, and outpatient clinic coordination. Scan the live roles below and apply to whichever ones fit.
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Job description
Physician Assistants/Nurse Practitioners-are you ready for a change? Don't miss this terrific opportunity to work with an underserved patient population in one of the beautiful communities in the U.S.!
Appalachian Mountain Health ("AMH"), a Federally Qualified Health Center network based in Asheville, NC, is hiring a Physician Assistant or Nurse Practitioner to join our exceptional clinical team. This position will be delivering quality-focused primary care services for patients in Black Mountain.
AMH provides comprehensive, accessible, patient-centered primary care to all, including low-income, medically underserved and uninsured populations, at six locations throughout Western North Carolina.
Our NP/PAs work closely with physicians, other advanced practitioners, behavioral health clinicians, and clinical and administrative support staff in a team-based approach to patient care.
Requirements:Required qualifications include:
- Physician Assistant /Nurse Practitioner degree from an accredited institution.
- Current North Carolina PA-C or NP license.
- CAQ.
- CPR certification.
- At least one year of experience in a primary care setting functioning at the full extent of training and licensure
- Strong commitment to practicing in a community health setting.
- Excellent interpersonal skills, as well as critical thinking skills, the ability to handle stressful situations and the capacity to function independently.
- High degree of initiative, judgment, discretion and decision-making to achieve AMH's mission.
In return, AMH offers an excellent compensation and benefits package, including medical, dental, vision, life, long-term and short-term disability insurance, relocation package, NHSC Loan Repayment, Continuing Medical Education allowance, Flexible Savings Account, 403(b) with match, generous PTO and Holiday policies and so much more!
AMH’s mission - to provide culturally competent, high-quality healthcare to the medically vulnerable population in western North Carolina - is rooted in a primary care and preventive services medical home model with fees for services adjusted on the basis of a patient’s ability to pay. AMH is an equal opportunity employer. We value a diverse workforce and encourage applications from all qualified individuals without regard to race, color, age, sex, gender identity or expression, sexual orientation, religion, marital status, citizenship, disability or veteran status.
To apply, please access the link to provide a resume and cover letter, including salary expectations. EOE. No Recruiters please.
Job Type: Full-time
Benefits:
- 401(k)
- 401(k) matching
- Dental insurance
- Employee assistance program
- Flexible spending account
- Health insurance
- Life insurance
- Paid time off
- Relocation assistance
- Retirement plan
- Tuition reimbursement
- Vision insurance
Medical Specialty:
- Primary Care
Schedule:
- 8-hour shift
- Day shift
- Monday to Friday
License/Certification:
- Physician Assistant or Nurse Practitioner License (Required)
Ability to Relocate: Relocate before starting work (Required)
Work Location: In person
See All 20 Practice Assistant Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find Practice Assistant JobsPractice Assistant Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Practice Assistant Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring


Top Industries Hiring
- Education
- Healthcare & Medical Services
What North Carolina Employers Look For
The qualifications that appear most often in practice assistant jobs across North Carolina.
- Active North Carolina Medical Board registration or recognized credentialing for clinical practice assistant roles
- Associate or bachelor's degree in healthcare administration, business, or a related field
- Proficiency with electronic health record systems such as Epic or Cerner
- One or more years of administrative or clinical support experience in a practice setting
- Strong written and verbal communication skills for patient or client-facing work
- Ability to manage scheduling, billing records, and provider coordination simultaneously
Practice Assistant Jobs in North Carolina: Frequently Asked Questions
How do you become a practice assistant in North Carolina?
The path depends on the setting. For medical practice assistant roles, North Carolina employers typically require at minimum a postsecondary certificate or associate degree in medical assisting or healthcare administration, and many prefer candidates who hold a Certified Medical Assistant credential recognized by the North Carolina Medical Board's credentialing standards. Legal practice assistant roles require no state license but usually expect a paralegal certificate or relevant degree. Starting at a clinic, physician group, or law firm in an administrative support role is the most common entry point.
Which companies hire practice assistants in North Carolina?
Employers hiring practice assistants in North Carolina right now include UNC Health, Western Carolina University, and Carolina Dentistry & Dentures, based on current listings on Migrate Mate as of August 2026. North Carolina's large integrated health systems and growing network of outpatient specialty clinics account for a significant share of ongoing openings across the state.
Which North Carolina cities have the most practice assistant jobs?
Charlotte, Monroe, and Cullowhee have the most practice assistant openings in North Carolina. Charlotte leads because of its concentration of large hospital systems and corporate healthcare offices, while Raleigh and Durham benefit from the Research Triangle's dense cluster of academic medical centers, specialty practices, and health-focused employers that consistently need administrative and clinical support staff.
Are there remote practice assistant jobs in North Carolina?
Yes, but they're rare. Practice assistant work is largely hands-on and tied to a physical office, clinic, or courtroom, which limits remote availability. About 18% of practice assistant openings tied to North Carolina are remote or hybrid as of August 2026, and those positions tend to involve billing, prior authorization, or administrative coordination tasks that don't require an on-site presence.
How can I get hired as a practice assistant in North Carolina with little or no experience?
The most realistic entry path is applying directly to entry-level medical or administrative assistant roles at North Carolina's large outpatient clinic networks or physician group practices, many of which offer on-the-job training. Atrium Health and UNC Health both run new graduate and associate-level support programs that bring in candidates without prior clinical experience. A Certified Medical Administrative Assistant credential gives candidates a clear edge, and lateral moves from front desk, patient services, or legal secretary roles are common ways to step into the title.
Where can I find and apply to practice assistant jobs in North Carolina?
You can find and apply to practice assistant jobs in North Carolina on Migrate Mate, which lists current openings from employers actively hiring across the state. Search the roles that match your background and experience level, then apply directly to the ones that fit your situation.
See All 20 Practice Assistant Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
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