Practice Manager Jobs in Missouri

Practice Manager jobs in Missouri are concentrated in Kansas City, St. Louis, and Springfield, where large health systems and multispecialty groups drive steady demand for experienced practice leaders at every level from single-site supervisor to regional director. Employers like BJC HealthCare, Saint Luke's Health System, and CoxHealth maintain consistent openings, particularly in medical group management, behavioral health, and outpatient specialty practices. Missouri's growing ambulatory care sector keeps demand for practice managers among the most active in the Midwest. Find a role that fits below and apply directly.

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Overview

Open roles22
Top employerMercy
Top citySt. Louis, MO
Cities hiring13
Work type100% Hybrid
Top credentialHigh school diploma or GED

Showing 4 of 22+ Practice Manager jobs

Practice Manager - Fertility & Reproductive Medicine
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Added 3d ago
Practice Manager - Fertility & Reproductive Medicine
Washington University in St. Louis
St. Louis, Missouri
Healthcare Administration
Human Resources
Nursing
Patient Services & Wellbeing
$71k - $110k/yr
Bachelor's degree
10,000+

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Practice Manager - Orthopedics - Mercy Jefferson
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Added 6d ago
Practice Manager - Orthopedics - Mercy Jefferson
Mercy
Festus, Missouri
Business Operations
Human Resources
Project Management
High school diploma or GED
10,000+

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Senior Practice Manager - Ear, Nose and Throat Surgery Clinic - FT
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Added 6d ago
Senior Practice Manager - Ear, Nose and Throat Surgery Clinic - FT
Mercy
Springfield, Missouri
Business Strategy
Project Management
Strategy & Corporate Development
High school diploma or GED
10,000+

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Practice Manager - Neosho
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Added 1w ago
Practice Manager - Neosho
Mercy
Neosho, Missouri
Clinical Support
Healthcare Administration
Human Resources
High school diploma or GED
10,000+

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See All 22 Practice Manager Jobs in Missouri

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Practice Manager Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
5 jobs
Kansas City
4 jobs
Springfield
3 jobs
Union
1 job
Festus
1 job
Neosho
1 job
Clinton
1 job
Columbia
1 job
Farmington
1 job

Practice Manager Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

Mercy5 open roles
NKC Health2 open roles
Heartland Dental2 open roles

What Missouri Employers Look For

The qualifications that appear most often in practice manager jobs across Missouri.

  • Bachelor's degree in healthcare administration, business, or a related field required
  • Two or more years of experience managing a medical or clinical practice setting
  • Demonstrated knowledge of medical billing, coding, and revenue cycle processes
  • Proficiency with electronic health record systems such as Epic or Cerner
  • Strong working knowledge of HIPAA compliance and healthcare regulatory standards
  • Certification from the Medical Group Management Association such as CMPE or FACMPE preferred

Practice Manager Jobs in Missouri: Frequently Asked Questions

How do you become a practice manager in Missouri?

Most Missouri employers require a bachelor's degree in healthcare administration, business administration, or a closely related field as the baseline for a practice manager role. Missouri does not require a state-issued license specific to practice management, but earning a credential through the Medical Group Management Association, such as the Certified Medical Practice Executive designation, strengthens candidacy considerably. Employers at major Missouri health systems typically expect clinical office or administrative management experience before hiring into the role.

Which companies hire practice managers in Missouri?

Missouri practice manager roles are posted by Mercy, NKC Health, and Heartland Dental and others right now, based on current listings on Migrate Mate as of October 2026. Missouri's large integrated health systems and independent multispecialty groups account for the majority of posted openings, with particularly consistent hiring in the Kansas City and St. Louis metro areas.

Which Missouri cities have the most practice manager jobs?

St. Louis, Kansas City, and Springfield lead Missouri for practice manager openings. Kansas City's concentration of hospital systems and outpatient campuses drives the largest share of postings, while St. Louis benefits from major academic medical centers and multispecialty groups anchored by employers like Barnes-Jewish and SSM Health, and Springfield's rapidly expanding CoxHealth and Mercy networks have made it one of the state's fastest-growing markets for clinical management roles.

Are there remote practice manager jobs in Missouri?

Yes, but they're rare. Practice management is largely an on-site role because it involves direct oversight of staff, patient flow, and facility operations. About 100% of practice manager openings tied to Missouri are remote or hybrid as of October 2026, and those tend to be concentrated in administrative functions such as revenue cycle management, credentialing oversight, or multi-site reporting roles that don't require a daily physical presence.

How can I get hired as a practice manager in Missouri with little or no experience?

The most realistic entry path is moving up from an established administrative role within a clinical setting, such as medical receptionist, billing specialist, or patient services coordinator at a Missouri health system. BJC HealthCare, Mercy, and SSM Health all run structured supervisor development tracks that allow high-performing administrative staff to transition into assistant or associate practice manager positions. Earning the MGMA's CMPE credential while still in a support role signals readiness and gives candidates a concrete edge over peers without formal management experience.

Where can I find and apply to practice manager jobs in Missouri?

You can find and apply to practice manager jobs in Missouri on Migrate Mate, which lists current Missouri openings across health systems, specialty groups, and outpatient practices throughout the state. Search the listings, find roles that match your experience and preferred location, and apply directly to the employers posting them.

See All 22 Practice Manager Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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