Public Relations Manager Jobs in San Francisco, CA
Public Relations Manager jobs in San Francisco are concentrated in the Financial District, SoMa, and Mission Bay, with strong demand from tech companies, healthcare systems, and consumer brands headquartered in the city. Employers hiring right now include Anthropic, Okta, and OpenAI. Find a role that fits below and apply directly.
Find Public Relations Manager JobsOverview
Showing 5 of 67+ Public Relations Manager jobs











The Position
Senior Manager, Product Public Relations
Why Genentech
From the beginning, Genentech has been a team of highly dedicated, passionate individuals. We are a place where people are united around a single purpose and an ambitious vision. Together, we aspire to deliver ever better health outcomes for patients while lowering overall healthcare costs. Our goal is to compel the customer to act on behalf of their patients while showing great commitment to the rare disease community, whose support is key. Utilizing innovative methods to identify patients who may benefit from treatment, we must take a highly strategic approach to patient access while assisting patients and their caregivers to navigate the healthcare system.
The Opportunity
This role is accountable for development and execution of communications and public relations strategies that are integrated with Commercial, Public Affairs & Access, U.S. Medical Affairs, cross-functional Global colleagues and other internal stakeholders. The candidate for this role will have an understanding of the communications and campaign requirements for reaching a wide range of audiences, including media, healthcare professionals, patients and policy makers.
Key Accountabilities
- Develop and execute insights-driven, high impact and integrated U.S. communications and public relations strategies in support of assigned therapy area and/or medicine(s), ensuring alignment with business objectives.
- Proactively engage media and influencers (traditional and social) around data and regulatory milestones and opportune media moments.
- Serve as media relations expert by maintaining relationships with key reporters, developing pitch angles with the goal of delivering thoughtful, positive news coverage.
- Support issues preparedness. Anticipate emerging issues and develop mitigation plans, including scenario planning, timely internal stakeholder alignment, message development, training for key internal stakeholders and issues supervising.
- Work closely with Legal, Regulatory, Medical and other key internal stakeholders on the review and approval of multiple materials/assets.
- Effectively manage agency relationship and budget to ensure delivery of their support through clear objectives, KPIs, continued drive for excellence and innovation.
Qualifications
- 8+ years of experience and established track-record of delivering impactful, strategic and content-rich communications programs, and proactive stakeholder management with demonstrable measures of success.
- Solid understanding of clinical data and regulatory milestones. Experience in translating scientific/technical content for a broad range of audiences.
- Experience in crafting consumer- and HCP-facing campaigns supporting brand strategic objectives; ability to apply patient journey and other audience insights to develop programming effecting behavior change.
- Ability to combine strategic thinking with hands-on-delivery.
- Ability to work independently, but knows when to flag potential issues to manager and leadership in a timely manner.
- Outstanding writing skills and proven media relations and digital communications skills.
- Strong oral and presentation skills; ability to negotiate and persuade.
- Significant experience in leading issues preparedness and issues management in a similar environment.
- Proven capability to influence and counsel senior leaders and teams across functions and geographical boundaries.
- Ability to work on multiple projects simultaneously and deal with rapidly changing priorities.
- Excellent interpersonal skills; hardworking team player and self-starter.
- Ability to work in a global environment including understanding of cultural differences.
- Requires about 25 to 35% domestic travel.
Location
- This position will be based in South San Francisco
- Relocation Benefits are not available for this role
Roche Operating Principles
- Put Patients First: I always act as if patients I know are in the room and do what’s best for them
- Follow the science: I seek answers through experiments, data and debate, and act on facts
- Act as one team: I care, collaborate and commit without boundaries, and trust others to do their part
- Embrace differences: I seek diverse perspectives, invite opposing views, and challenge myself and others
- Accelerate learning: I push to learn new things even if difficult, and openly share my successes and failures
- Simplify radically: I eliminate complexity, reuse with pride, and accomplish more with less
- Make impact now: I take accountability to do what’s right, deliver value fast, and don’t wait for certainty
- Think long term: I choose actions today that benefit future generations
The expected salary range for this position based on the primary location of California is $141,700.00 – $263,100.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position is eligible to earn incentive compensation that is calculated and paid in accordance with the applicable Incentive Compensation Plan for the role. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
See All 67 Public Relations Manager Jobs in San Francisco
Find roles in San Francisco that match your experience and apply in just a few clicks.
Find Public Relations Manager JobsPublic Relations Manager Job Market in San Francisco
Who's Hiring
- Anthropic7

- Okta4

- OpenAI3

- Flexport3

- Genentech3

Top Industries Hiring
- Technology & Software22
- Science & Research11
- Education4
- Transportation & Logistics3
- Consulting & Professional Services3
Public Relations Manager Jobs in San Francisco: Frequently Asked Questions
How do I get a public relations manager job in San Francisco?
The strongest path is targeting San Francisco's dominant hiring sectors: enterprise tech, biotech and life sciences, financial services, and consumer brand companies clustered in SoMa and the Financial District. Candidates with experience managing media relations in fast-moving environments, crisis communications, or product launch campaigns stand out here. Tailoring your portfolio to show Bay Area media relationships and tech or biotech fluency gives you a clear edge over generalist applicants.
Which companies hire public relations managers in San Francisco?
San Francisco public relations manager roles are posted by Anthropic, Okta, and OpenAI and others right now, based on current listings on Migrate Mate as of June 2026. The city's employer base skews toward publicly traded tech firms, venture-backed startups, major healthcare systems, and global financial institutions, all of which maintain active in-house communications teams.
Are there remote public relations manager jobs in San Francisco?
Yes, though with limits. Public relations manager work is moderately remote-friendly, since media outreach, writing, and strategy can be done off-site, while press events, executive prep, and stakeholder meetings typically require in-person presence. About 23% of public relations manager openings tied to San Francisco are remote or hybrid as of June 2026, with fully remote roles most common at tech companies and hybrid arrangements most common at financial and healthcare employers.
How can I get a public relations manager job in San Francisco with little or no experience?
The most realistic entry path is starting in a coordinator or specialist role at a San Francisco PR agency, tech startup, or nonprofit, where smaller teams let you take on broader responsibilities faster. Many Bay Area companies also hire communications associates who work alongside senior managers on product launches and media relations. Building local media contacts and contributing to open-source or community-facing communications projects strengthens your case significantly in this market.
Which industries hire the most public relations managers in San Francisco?
Most public relations manager openings in San Francisco sit in Technology & Software, Science & Research, and Education, per current listings on Migrate Mate as of June 2026. San Francisco's concentration of publicly traded tech companies, major biotech campuses in Mission Bay, and global financial institutions creates consistent demand for communications professionals who can manage complex stakeholder narratives and high-visibility media environments.
Related Jobs in California
See All 67 Public Relations Manager Jobs in San Francisco
Find roles in San Francisco that match your experience and apply in just a few clicks.
Find Public Relations Manager Jobs